Analysis of glycoforms on the glycosylation site and the glycans in monoclonal antibody biopharmaceuticals

Journal of Separation Science

Volumn 35, Issue 3, 2012, Pages 341-350

  Uçaktürk, Ebru ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Glycan analysis; Glycoform analysis; Monoclonal antibody biopharmaceuticals

Indexed keywords

ANALYTICAL METHOD; BIOLOGICAL ACTIVITIES; BIOPHARMACEUTICALS; CARDIO-VASCULAR DISEASE; CHROMATOGRAPHIC METHODS; GLYCAN ANALYSIS; GLYCANS; GLYCOFORM ANALYSIS; GLYCOFORMS; HUMAN USE; POST-TRANSLATIONAL MODIFICATIONS; THERAPEUTIC MONOCLONAL ANTIBODIES;

CHROMATOGRAPHIC ANALYSIS; DISEASES; ESTERIFICATION; MONOCLONAL ANTIBODIES;

GLYCOSYLATION;

ABATACEPT; ABCIXIMAB; ADALIMUMAB; ALEFACEPT; ALEMTUZUMAB; BASILIXIMAB; BEVACIZUMAB; CERTOLIZUMAB PEGOL; CETUXIMAB; DACLIZUMAB; ECULIZUMAB; EDRECOLOMAB; EFALIZUMAB; ETANERCEPT; GEMTUZUMAB OZOGAMICIN; GLYCAN; GLYCOPROTEIN; HERCEPTINE; IBRITUMOMAB TIUXETAN; IMMUNOGLOBULIN; INFLIXIMAB; MONOCLONAL ANTIBODY; NATALIZUMAB; NIMOTUZUMAB; OKT 3; OMALIZUMAB; PALIVIZUMAB; PANITUMUMAB; RANIBIZUMAB; RILONACEPT; RITUXIMAB; ROMIPLOSTIM; TOSITUMOMAB I 131; UNCLASSIFIED DRUG; UNINDEXED DRUG; VECTIBIS;

ANALYTIC METHOD; CARDIOVASCULAR DISEASE; GLYCOSYLATION; HEALTH CARE QUALITY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; QUALITY CONTROL; REPRODUCIBILITY; REVIEW;

ANTIBODIES, MONOCLONAL; BINDING SITES; BIOPHARMACEUTICS; CARBOHYDRATE CONFORMATION; CHROMATOGRAPHY; GLYCOSYLATION; HUMANS; IMMUNOGLOBULINS; POLYSACCHARIDES;

EID: 84856103054     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100684     Document Type: Review

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