A comparison of three techniques for quantitative carbohydrate analysis used in characterization of therapeutic antibodies

Carbohydrate Research

Volumn 341, Issue 3, 2006, Pages 410-419

  Siemiatkoski, Joseph ^a   Lyubarskaya, Yelena ^a   Houde, Damian ^a   Tep, Samnang ^a   Mhatre, Rohin ^a  

^a BIOGEN   (United States)

Author keywords

2 AA ESIMS; Galactosylation; Immunoglobulin; MALDI TOF MS

Indexed keywords

ALKYLATION; ANTIBODIES; ASSAYS; CORRELATION METHODS; ENZYMES; SENSITIVITY ANALYSIS;

2-AA/ESIMS; GALACTOSYLATION; IMMUNOGLOBULIN; MALDI-TOF MS;

CARBOHYDRATES;

ANTHRANILIC ACID; CARBOHYDRATE; FLUORESCENT DYE; IMMUNOGLOBULIN G; PARAPROTEIN; RECOMBINANT PROTEIN;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CARBOHYDRATE ANALYSIS; ELECTROSPRAY MASS SPECTROMETRY; IN VITRO STUDY; INTERMETHOD COMPARISON; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS;

ANTIBODIES, MONOCLONAL; CARBOHYDRATE SEQUENCE; CARBOHYDRATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; FLUORESCENCE; GLYCOSYLATION; IMMUNOGLOBULINS; MOLECULAR SEQUENCE DATA; N-ACETYLLACTOSAMINE SYNTHASE; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STREPTOCOCCUS PNEUMONIAE;

EID: 30744447269     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2005.11.024     Document Type: Article

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