Comparison of LC and LC/MS Methods for Quantifying N-Glycosylation in Recombinant IgGs

Journal of the American Society for Mass Spectrometry

Volumn 19, Issue 11, 2008, Pages 1643-1654

  Sinha, Sandipan ^a   Pipes, Gary ^b   Topp, Elizabeth M ^a   Bondarenko, Pavel V ^c   Treuheit, Michael J ^b   Gadgil, Himanshu S ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b AMGEN INC   (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; ESTERIFICATION; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY;

EXTRACTED ION CHROMATOGRAMS; FC FRAGMENTS; GLYCANS; GLYCOFORMS; GLYCOSYLATED; HEAVY CHAINS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIES; HPLC ANALYSES; LIMITED PROTEOLYSES; MS ANALYSES; NORMAL PHASE; SAMPLE PREPARATIONS; TIME OF FLIGHTS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

GLYCOPEPTIDASE; IMMUNOGLOBULIN G;

ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION PAIR CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN DEGRADATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; POLYSACCHARIDES; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPSIN;

EID: 55149085231     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.07.004     Document Type: Article

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