메뉴 건너뛰기




Volumn 62, Issue 3, 2012, Pages 1182-1190

Selective phosphodiesterase inhibitors improve performance on the ED/ID cognitive task in rats

Author keywords

Attention; Cognition; Executive function; Frontal cortex; Learning; Set shifting

Indexed keywords

BAY 60 7550; ESTERASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PAPAVERINE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM; SILDENAFIL; UNCLASSIFIED DRUG;

EID: 84856078086     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.08.008     Document Type: Article
Times cited : (63)

References (97)
  • 2
    • 0036667081 scopus 로고    scopus 로고
    • Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats
    • DOI 10.1101/lm.48602
    • M.D. Barense, M.T. Fox, and M.G. Baxter Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats Learn. Mem. 9 4 2002 191 201 (Pubitemid 36240691)
    • (2002) Learning and Memory , vol.9 , Issue.4 , pp. 191-201
    • Barense, M.D.1    Fox, M.T.2    Baxter, M.G.3
  • 4
    • 36248972246 scopus 로고    scopus 로고
    • Phosphodiesterase inhibitors-Are they potential neuroleptic drugs?
    • DOI 10.1016/j.bbr.2007.08.002, PII S0166432807004020
    • A. Becker, and G. Grecksch Phosphodiesterase inhibitors - are they potential neuroleptic drugs? Behav. Brain Res. 186 2008 155 160 (Pubitemid 350122747)
    • (2008) Behavioural Brain Research , vol.186 , Issue.2 , pp. 155-160
    • Becker, A.1    Grecksch, G.2
  • 5
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • J.M. Birrell, and V.J. Brown Medial frontal cortex mediates perceptual attentional set shifting in the rat J. Neurosci. 20 11 2000 4320 4324 (Pubitemid 30365702)
    • (2000) Journal of Neuroscience , vol.20 , Issue.11 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 6
    • 3342991544 scopus 로고    scopus 로고
    • Potency, selectivity, and consequences of nonselectivity of PDE inhibition
    • E. Bischoff Potency, selectivity, and consequences of nonselectivity of PDE inhibition Int. J. Impot Res. 16 Suppl. 1 2004 Jun S11 S14
    • (2004) Int. J. Impot Res. , vol.16 , Issue.SUPPL. 1
    • Bischoff, E.1
  • 8
    • 0034660569 scopus 로고    scopus 로고
    • The neurodevelopmental frontostriatal disorders: Evolutionary adaptiveness and anomalous lateralization
    • DOI 10.1006/brln.2000.2308
    • J.L. Bradshaw, and D.M. Sheppard The neurodevelopmental frontostriatal disorders: evolutionary adaptiveness and anomalous lateralization Brain Lang. 73 2 2000 297 320 (Pubitemid 30408053)
    • (2000) Brain and Language , vol.73 , Issue.2 , pp. 297-320
    • Bradshaw, J.L.1    Sheppard, D.M.2
  • 9
    • 37349069210 scopus 로고    scopus 로고
    • Expression of phosphodiesterase 4 is altered in the brains of subjects with autism
    • DOI 10.1097/WNR.0b013e3282f16dca, PII 0000175620071119000018
    • N.N. Braun, T.J. Reutiman, S. Lee, T.D. Folsom, and S.H. Fatemi Expression of phosphodiesterase 4 is altered in the brains of subjects with autism Neuroreport 18 17 2007 Nov 19 1841 1844 (Pubitemid 350303763)
    • (2007) NeuroReport , vol.18 , Issue.17 , pp. 1841-1844
    • Braun, N.N.1    Reutiman, T.J.2    Lee, S.3    Folsom, T.D.4    Fatemi, S.H.5
  • 10
    • 0031795737 scopus 로고    scopus 로고
    • Hepatotoxicity related to intracavernous pharmacotherapy with papaverine
    • DOI 10.1016/S0090-4295(98)00290-8, PII S0090429598002908
    • S.L. Brown, C.A. Haas, M. Koehler, D.R. Bodner, and A.D. Seftel Hepatotoxicity related to intracavernous pharmacotherapy with papaverine Urology 52 5 1998 844 847 (Pubitemid 28489715)
    • (1998) Urology , vol.52 , Issue.5 , pp. 844-847
    • Brown, S.L.1    Haas, C.A.2    Koehler, M.3    Bodner, D.R.4    Seftel, A.D.5
  • 11
    • 4344701960 scopus 로고    scopus 로고
    • Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set-shifting
    • DOI 10.1111/j.1460-9568.2004.03548.x
    • K.C. Chen, M.G. Baxter, and J.S. Rodefer Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set-shifting Eur. J. Neurosci. 20 4 2004 1081 1088 (Pubitemid 39141315)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.4 , pp. 1081-1088
    • Chen, K.C.1    Baxter, M.G.2    Rodefer, J.S.3
  • 12
    • 0019516961 scopus 로고
    • Testing cyclic AMP mediation of memory: Reversal of α-methyl-p- tyrosine-induced amnesia
    • DOI 10.1007/BF00432678
    • D.L. Chutae, J.W. Villiger, and N.F. Kirton Testing cyclic AMP mediation of memory: reversal of alpha-methyl-p-tyrosine-induced amnesia Psychopharmacology (Berl.) 74 2 1981 129 131 (Pubitemid 11126540)
    • (1981) Psychopharmacology , vol.74 , Issue.2 , pp. 129-131
    • Chute, D.L.1    Villiger, J.W.2    Kirton, N.F.3
  • 13
    • 0016698821 scopus 로고
    • Electroencephalographic and behavioral changes associated with papaverine administration in healthy geriatric subjects
    • J.O. Cole, R.J. Branconnier, and G.F. Martin Electroencephalographic and behavioral changes associated with papaverine administration in healthy geriatric subjects J. Am. Geriatr. Soc. 23 7 1975 295 300
    • (1975) J. Am. Geriatr. Soc. , vol.23 , Issue.7 , pp. 295-300
    • Cole, J.O.1    Branconnier, R.J.2    Martin, G.F.3
  • 15
    • 33646366904 scopus 로고    scopus 로고
    • The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord
    • DOI 10.1016/j.jchemneu.2006.02.006, PII S0891061806000226
    • J. de Vente, M. Markerink-van Ittersum, and J.S. Vles The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord J. Chem. Neuroanat. 31 4 2006 Jun 275 303 (Epub 2006 Apr 18) (Pubitemid 43668706)
    • (2006) Journal of Chemical Neuroanatomy , vol.31 , Issue.4 , pp. 275-303
    • De Vente, J.1    Markerink-van Ittersum, M.2    Vles, J.S.H.3
  • 16
    • 28344453810 scopus 로고    scopus 로고
    • Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition
    • DOI 10.1007/s00213-005-0232-z
    • B.D. Devan, J.L. Bowker, K.B. Duffy, I.S. Bharati, M. Jimenez, D. Sierra-Mercado Jr.; C.M. Nelson, E.L. Spangler, and D.K. Ingram Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition Psychopharmacology (Berl.) 183 4 2006 Jan 439 445 (Pubitemid 41721145)
    • (2006) Psychopharmacology , vol.183 , Issue.4 , pp. 439-445
    • Devan, B.D.1    Bowker, J.L.2    Duffy, K.B.3    Bharati, I.S.4    Jimenez, M.5    Sierra-Mercado Jr., D.6    Nelson, C.M.7    Spangler, E.L.8    Ingram, D.K.9
  • 17
    • 0029967425 scopus 로고    scopus 로고
    • Dissociation in prefrontal cortex of affective and attentional shifts
    • DOI 10.1038/380069a0
    • R. Dias, T.W. Robbins, and A.C. Roberts Dissociation in prefrontal cortex of affective and attentional shifts Nature 380 6569 1996 69 72 (Pubitemid 26076238)
    • (1996) Nature , vol.380 , Issue.6569 , pp. 69-72
    • Dias, R.1    Robbins, T.W.2    Roberts, A.C.3
  • 18
    • 0030698098 scopus 로고    scopus 로고
    • Dissociable forms of inhibitory control within prefrontal cortex with an analog of the wisconsin card sort test: Restriction to novel situations and independence from 'on-line' processing
    • R. Dias, T.W. Robbins, and A.C. Roberts Dissociable forms of inhibitory control within prefrontal cortex with an analog of the Wisconsin Card Sort Test: restriction to novel situations and independence from "on-line" processing J. Neurosci. 17 23 1997 9285 9297 (Pubitemid 27498455)
    • (1997) Journal of Neuroscience , vol.17 , Issue.23 , pp. 9285-9297
    • Dias, R.1    Robbins, T.W.2    Roberts, A.C.3
  • 19
    • 46549084175 scopus 로고    scopus 로고
    • The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging
    • K. Domek-Łopacińska, and J.B. Strosznajder The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging Brain Res. 1216 2008 Jun 24 68 77
    • (2008) Brain Res. , vol.1216 , pp. 68-77
    • Domek-ŁOpacińska, K.1    Strosznajder, J.B.2
  • 20
    • 0031451614 scopus 로고    scopus 로고
    • Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats
    • T. Egawa, K. Mishima, Y. Matsumoto, K. Iwasaki, K. Iwasaki, and M. Fujiwara Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats Jpn. J. Pharmacol. 75 3 1997 275 281 (Pubitemid 28000172)
    • (1997) Japanese Journal of Pharmacology , vol.75 , Issue.3 , pp. 275-281
    • Egawa, T.1    Mishima, K.2    Matsumoto, Y.3    Iwasaki, K.4    Iwasaki, K.5    Fujiwara, M.6
  • 21
    • 0030913737 scopus 로고    scopus 로고
    • Assessment of the dysexecutive syndrome in schizophrenia
    • DOI 10.1017/S0033291797004790
    • J.J. Evans, S.E. Chua, P.J. McKenna, and B.A. Wilson Assessment of the dysexecutive syndrome in schizophrenia Psychol. Med. 27 3 1997 May 635 646 (Pubitemid 27216189)
    • (1997) Psychological Medicine , vol.27 , Issue.3 , pp. 635-646
    • Evans, J.J.1    Chua, S.E.2    Mckenna, P.J.3    Wilson, B.A.4
  • 22
    • 30944469609 scopus 로고    scopus 로고
    • Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting
    • DOI 10.1038/sj.npp.1300825, PII 1300825
    • S.B. Floresco, O. Magyar, S. Ghods-Sharifi, C. Vexelman, and M.T. Tse Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting Neuropsychopharmacology 31 2 2006 Feb 297 309 (Pubitemid 43113395)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.2 , pp. 297-309
    • Floresco, S.B.1    Magyar, O.2    Ghods-Sharifi, S.3    Vexelman, C.4    Tse, M.T.L.5
  • 23
    • 0037439912 scopus 로고    scopus 로고
    • Perceptual attentional set-shifting is impaired in rats with neurotoxic lesions of posterior parietal cortex
    • M.T. Fox, M.D. Barense, and M.G. Baxter Perceptual attentional set-shifting is impaired in rats with neurotoxic lesions of posterior parietal cortex J. Neurosci. 23 2 2003 676 681 (Pubitemid 36139566)
    • (2003) Journal of Neuroscience , vol.23 , Issue.2 , pp. 676-681
    • Fox, M.T.1    Barense, M.D.2    Baxter, M.G.3
  • 24
    • 0027203084 scopus 로고
    • Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons
    • U. Frey, Y.Y. Huang, and E.R. Kandel Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons Science 260 5114 1993 Jun 11 1661 1664 (Pubitemid 23247151)
    • (1993) Science , vol.260 , Issue.5114 , pp. 1661-1664
    • Frey, U.1    Huang, Y.-Y.2    Kandel, E.R.3
  • 26
    • 0030894408 scopus 로고    scopus 로고
    • Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture
    • DOI 10.1016/S0006-8993(97)00093-0, PII S0006899397000930
    • K. Goto, H. Mochizuki, T. Hattori, N. Nakamura, and Y. Mizuno Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture Brain Res. 754 1-2 1997 260 268 (Pubitemid 27170275)
    • (1997) Brain Research , vol.754 , Issue.1-2 , pp. 260-268
    • Goto, K.1    Mochizuki, H.2    Hattori, T.3    Nakamura, N.4    Mizuno, Y.5
  • 28
    • 0034644113 scopus 로고    scopus 로고
    • The basal ganglia
    • A.M. Graybiel The basal ganglia Curr. Biol. 10 14 2000 R509 R511
    • (2000) Curr. Biol. , vol.10 , Issue.14
    • Graybiel, A.M.1
  • 29
    • 0029918481 scopus 로고    scopus 로고
    • What are the functional consequences of neurocognitive deficits in schizophrenia?
    • M.F. Green What are the functional consequences of neurocognitive deficits in schizophrenia? Am. J. Psychiatry 153 1996 321 330 (Pubitemid 26074706)
    • (1996) American Journal of Psychiatry , vol.153 , Issue.3 , pp. 321-330
    • Green, M.F.1
  • 30
    • 34547217870 scopus 로고    scopus 로고
    • Cognition, drug treatment, and functional outcome in schizophrenia: A tale of two transitions
    • M.E. Green Cognition, drug treatment, and functional outcome in schizophrenia: a tale of two transitions Am. J. Psychiatry 164 2007 992 994
    • (2007) Am. J. Psychiatry , vol.164 , pp. 992-994
    • Green, M.E.1
  • 31
    • 45749156388 scopus 로고    scopus 로고
    • Antipsychotic-like properties of phosphodiesterase 4 inhibitors: Evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle
    • DOI 10.1124/jpet.108.138586
    • T.B. Halene, and S.J. Siegel Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2- imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle J. Pharmacol. Exp. Ther. 326 1 2008 Jul 230 239 (Epub 2008 Apr 17) (Pubitemid 351872113)
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.326 , Issue.1 , pp. 230-239
    • Halene, T.B.1    Siegel, S.J.2
  • 32
    • 40749161505 scopus 로고    scopus 로고
    • Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice
    • DOI 10.1016/j.euroneuro.2007.08.002, PII S0924977X07001721
    • A.L.O. Hebb, H.A. Robertson, and E.M. Denovan-Wright Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice Eur. Neuropsychopharmacol. 18 2008 339 363 (Pubitemid 351381352)
    • (2008) European Neuropsychopharmacology , vol.18 , Issue.5 , pp. 339-363
    • Hebb, A.L.O.1    Robertson, H.A.2    Denovan-Wright, E.M.3
  • 33
    • 0031048406 scopus 로고    scopus 로고
    • Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents
    • DOI 10.1016/S0014-2999(96)00969-7, PII S0014299996009697
    • T. Imanishi, A. Sawa, Y. Ichimaru, M. Miyashiro, S. Kato, T. Yamamoto, and S. Ueki Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents Eur. J. Pharmacol. 321 3 1997 Mar 5 273 278 (Pubitemid 27105928)
    • (1997) European Journal of Pharmacology , vol.321 , Issue.3 , pp. 273-278
    • Imanishi, T.1    Sawa, A.2    Ichimaru, Y.3    Miyashiro, M.4    Kato, S.5    Yamamoto, T.6    Ueki, S.7
  • 34
    • 0032903301 scopus 로고    scopus 로고
    • The neuropsychopharmacology of phencyclidine: From NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia
    • DOI 10.1016/S0893-133X(98)00060-8, PII S0893133X98000608
    • J.D. Jentsch, and R.H. Roth The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia Neuropsychopharmacology 20 3 1999 Mar 201 225 (Pubitemid 29067401)
    • (1999) Neuropsychopharmacology , vol.20 , Issue.3 , pp. 201-225
    • Jentsch, J.D.1    Roth, R.H.2
  • 35
    • 0035205333 scopus 로고    scopus 로고
    • Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats
    • J.D. Jentsch, and J.R. Taylor Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats Neuropsychopharmacology 24 1 2001 Jan 66 74
    • (2001) Neuropsychopharmacology , vol.24 , Issue.1 , pp. 66-74
    • Jentsch, J.D.1    Taylor, J.R.2
  • 36
    • 0030862672 scopus 로고    scopus 로고
    • Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine
    • DOI 10.1126/science.277.5328.953
    • J.D. Jentsch, D.E. Redmond, J.D. Elsworth, J.R. Taylor, K.D. Youngren, and R.H. Roth Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine Science 277 1997 953 955 (Pubitemid 27366680)
    • (1997) Science , vol.277 , Issue.5328 , pp. 953-955
    • Jentsch, J.D.1    Redmond Jr., D.E.2    Elsworth, J.D.3    Taylor, J.R.4    Youngren, K.D.5    Roth, R.H.6
  • 37
    • 0031808409 scopus 로고    scopus 로고
    • Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant- induced hyperlocomotion
    • DOI 10.1016/S0893-133X(98)00004-9, PII S0893133X98000049
    • J.D. Jentsch, J.R. Taylor, and R.H. Roth Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion Neuropsychopharmacology 19 2 1998 Aug 105 113 (Pubitemid 28288436)
    • (1998) Neuropsychopharmacology , vol.19 , Issue.2 , pp. 105-113
    • Jentsch, J.D.1    Taylor, J.R.2    Roth, R.H.3
  • 38
    • 3342953638 scopus 로고    scopus 로고
    • Implications of PDE4 structure on inhibitor selectivity across PDE families
    • H. Ke Implications of PDE4 structure on inhibitor selectivity across PDE families Int. J. Impot Res. 16 Suppl. 1 2004 Jun S24 S27
    • (2004) Int. J. Impot Res. , vol.16 , Issue.SUPPL. 1
    • Ke, H.1
  • 39
    • 0034851624 scopus 로고    scopus 로고
    • Effects of ketamine in normal and schizophrenic volunteers
    • DOI 10.1016/S0893-133X(01)00243-3, PII S0893133X01002433
    • A.C. Lahti, M.A. Weiler, B.A. Tamara Michaelidis, A. Parwani, and C.A. Tamminga Effects of ketamine in normal and schizophrenic volunteers Neuropsychopharmacology 25 4 2001 Oct 455 467 (Pubitemid 32830950)
    • (2001) Neuropsychopharmacology , vol.25 , Issue.4 , pp. 455-467
    • Lahti, A.C.1    Weiler, M.A.2    Michaelidis, T.3    Parwani, A.4    Tamminga, C.A.5
  • 40
    • 77956925425 scopus 로고    scopus 로고
    • Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues
    • V. Lakics, E.H. Karran, and F.G. Boess Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues Neuropharmacology 59 6 2010 Nov 367 374
    • (2010) Neuropharmacology , vol.59 , Issue.6 , pp. 367-374
    • Lakics, V.1    Karran, E.H.2    Boess, F.G.3
  • 41
    • 59449090522 scopus 로고    scopus 로고
    • Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat
    • G. Levallet, M. Hotte, M. Boulouard, and F. Dauphin Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat Psychopharmacology (Berl.) 202 2009 125 139
    • (2009) Psychopharmacology (Berl.) , vol.202 , pp. 125-139
    • Levallet, G.1    Hotte, M.2    Boulouard, M.3    Dauphin, F.4
  • 43
    • 32044472303 scopus 로고    scopus 로고
    • Critical role of nitric oxide-cGMP cascade in the formation of cAMP-dependent long-term memory
    • DOI 10.1101/lm.130506
    • Y. Matsumoto, S. Unoki, H. Aonuma, and M. Mizunami Critical role of nitric oxide-cGMP cascade in the formation of cAMP-dependent long-term memory Learn. Mem. 13 1 2006 Jan-Feb 35 44 (Pubitemid 43200817)
    • (2006) Learning and Memory , vol.13 , Issue.1 , pp. 35-44
    • Matsumoto, Y.1    Unoki, S.2    Aonuma, H.3    Mizunami, M.4
  • 44
    • 5444251165 scopus 로고    scopus 로고
    • Phosphodiesterase inhibitors: A novel mechanism for receptor-independent antipsychotic medications
    • DOI 10.1016/j.neuroscience.2004.07.038, PII S0306452204006530
    • C.R. Maxwell, S.J. Kanes, T. Abel, and S.J. Siegel Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications Neuroscience 129 1 2004 101 107 (Pubitemid 39360946)
    • (2004) Neuroscience , vol.129 , Issue.1 , pp. 101-107
    • Maxwell, C.R.1    Kanes, S.J.2    Abel, T.3    Siegel, S.J.4
  • 45
    • 33947302705 scopus 로고    scopus 로고
    • Phosphodiesterase 10A inhibitors: A novel approach to the treatment of the symptoms of schizophrenia
    • F.S. Menniti, T.A. Chappie, J.M. Humphrey, and C.J. Schmidt Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia Curr. Opin. Investig. Drugs 8 1 2007 Jan 54 59 (Pubitemid 46438266)
    • (2007) Current Opinion in Investigational Drugs , vol.8 , Issue.1 , pp. 54-59
    • Menniti, F.S.1    Chappie, T.A.2    Humphrey, J.M.3    Schmidt, C.J.4
  • 46
    • 0017869566 scopus 로고
    • Guanylate cyclase: Activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin
    • F. Murad, C.K. Mittal, W.P. Arnold, S. Katsuki, and H. Kimura Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin Adv. Cyclic Nucleotide Res. 9 1978 145 158
    • (1978) Adv. Cyclic Nucleotide Res. , vol.9 , pp. 145-158
    • Murad, F.1    Mittal, C.K.2    Arnold, W.P.3    Katsuki, S.4    Kimura, H.5
  • 47
    • 0016608580 scopus 로고
    • Relieving select symptoms of the elderly
    • 142
    • J.J. Nelson Relieving select symptoms of the elderly Geriatrics 30 3 1975 133 139 142
    • (1975) Geriatrics , vol.30 , Issue.3 , pp. 133-139
    • Nelson, J.J.1
  • 48
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • E.J. Nestler, and S.E. Hyman Animal models of neuropsychiatric disorders Nat. Neurosci. 13 10 2010 Oct 1161 1169
    • (2010) Nat. Neurosci. , vol.13 , Issue.10 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 49
    • 36048946601 scopus 로고    scopus 로고
    • Double dissociation of attentional resources: Prefrontal versus cingulate cortices
    • DOI 10.1523/JNEUROSCI.2745-07.2007
    • C. Ng, M.I. Noblejas, J.S. Rodefer, C. Smith, and A. Poremba Double dissociation of attentional resources: prefrontal versus cingulate cortices J. Neurosci. 27 45 2007 12123 12131 (Pubitemid 350085468)
    • (2007) Journal of Neuroscience , vol.27 , Issue.45 , pp. 12123-12131
    • Ng, C.-W.1    Noblejas, M.I.2    Rodefer, J.S.3    Smith, C.B.4    Poremba, A.5
  • 51
    • 0032694066 scopus 로고    scopus 로고
    • NMDA receptor hypofunction model of schizophrenia
    • J.W. Olney, J.W. Newcomer, and N.B. Farber NMDA receptor hypofunction model of schizophrenia J. Psychiatr. Res. 33 6 1999 Nov-Dec 523 533
    • (1999) J. Psychiatr. Res. , vol.33 , Issue.6 , pp. 523-533
    • Olney, J.W.1    Newcomer, J.W.2    Farber, N.B.3
  • 52
    • 0026005933 scopus 로고
    • Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man
    • A.M. Owen, A.C. Roberts, C.E. Polkey, B.J. Sahakian, and T.W. Robbins Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man Neuropsychologia 29 10 1991 993 1006
    • (1991) Neuropsychologia , vol.29 , Issue.10 , pp. 993-1006
    • Owen, A.M.1    Roberts, A.C.2    Polkey, C.E.3    Sahakian, B.J.4    Robbins, T.W.5
  • 53
    • 33746381229 scopus 로고    scopus 로고
    • Modulatory effect of sildenafil in diabetes and electroconvulsive shock-induced cognitive dysfunction in rats
    • C.S. Patil, V.P. Singh, and S.K. Kulkarni Modulatory effect of sildenafil in diabetes and electroconvulsive shock-induced cognitive dysfunction in rats Pharmacol. Rep. 58 3 2006 May-Jun 373 380 (Pubitemid 44111072)
    • (2006) Pharmacological Reports , vol.58 , Issue.3 , pp. 373-380
    • Patil, C.S.1    Singh, V.P.2    Kulkarni, S.K.3
  • 54
    • 0242460552 scopus 로고    scopus 로고
    • Dysregulation of protein kinase A signaling in the aged prefrontal cortex: New strategy for treating age-related cognitive decline
    • DOI 10.1016/S0896-6273(03)00694-9
    • B.P. Ramos, S.G. Birnbaum, I. Lindenmayer, S.S. Newton, R.S. Duman, and A.F. Arnsten Dysregulation of protein kinase a signaling in the aged prefrontal cortex: new strategy for treating age-related cognitive decline Neuron 40 4 2003 835 845 (Pubitemid 37431042)
    • (2003) Neuron , vol.40 , Issue.4 , pp. 835-845
    • Ramos, B.P.1    Birnbaum, S.G.2    Lindenmayer, I.3    Newton, S.S.4    Duman, R.S.5    Arnsten, A.F.T.6
  • 55
    • 33845299524 scopus 로고    scopus 로고
    • α2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals
    • DOI 10.1101/lm.298006
    • B.P. Ramos, D. Stark, L. Verduzco, C.H. van Dyck, and A.F. Arnsten Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals Learn. Mem. 13 6 2006 Nov-Dec 770 776 (Pubitemid 44871678)
    • (2006) Learning and Memory , vol.13 , Issue.6 , pp. 770-776
    • Ramos, B.P.1    Stark, D.2    Verduzco, L.3    Van Dyck, C.H.4    Arnsten, A.F.T.5
  • 58
    • 34249871389 scopus 로고    scopus 로고
    • Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains
    • DOI 10.1111/j.1460-9568.2007.05589.x
    • E. Reyes-Irisarri, M. Markerink-Van Ittersum, G. Mengod, and J. de Vente Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains Eur. J. Neurosci. 25 11 2007 Jun 3332 3338 (Pubitemid 46872773)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.11 , pp. 3332-3338
    • Reyes-Irisarri, E.1    Markerink-Van Ittersum, M.2    Mengod, G.3    De Vente, J.4
  • 59
    • 0031662243 scopus 로고    scopus 로고
    • A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: Implications for theories of executive functioning and cognitive aging
    • DOI 10.1017/S1355617798455073
    • T.W. Robbins, M. James, A.M. Owen, B.J. Sahakian, A.D. Lawrence, L. McInnes, and P.M. Rabbitt A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging. Cambridge Neuropsychological Test Automated Battery J. Int. Neuropsychol. Soc. 4 1998 474 490 (Pubitemid 28461619)
    • (1998) Journal of the International Neuropsychological Society , vol.4 , Issue.5 , pp. 474-490
    • Robbins, T.W.1    James, M.2    Owen, A.M.3    Sahakian, B.J.4    Lawrence, A.D.5    Mcinnes, L.6    Rabbitt, P.M.A.7
  • 60
    • 37549005095 scopus 로고    scopus 로고
    • Naltrexone reverses age-induced cognitive deficits in rats
    • J.S. Rodefer, and T.N. Nguyen Naltrexone reverses age-induced cognitive deficits in rats Neurobiol. Aging 29 2008 309 313
    • (2008) Neurobiol. Aging , vol.29 , pp. 309-313
    • Rodefer, J.S.1    Nguyen, T.N.2
  • 61
    • 16244376475 scopus 로고    scopus 로고
    • PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats
    • DOI 10.1111/j.1460-9568.2005.03937.x
    • J.S. Rodefer, E.R. Murphy, and M.G. Baxter PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats Eur. J. Neurosci. 21 4 2005 1070 1076 (Pubitemid 40461058)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.4 , pp. 1070-1076
    • Rodefer, J.S.1    Murphy, E.R.2    Baxter, M.G.3
  • 62
    • 51749091526 scopus 로고    scopus 로고
    • Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: Comparison among antipsychotics
    • J.S. Rodefer, T.N. Nguyen, J.J. Karlsson, and J. Arnt Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics Neuropsychopharmacology 33 11 2008 Oct 2657 2666
    • (2008) Neuropsychopharmacology , vol.33 , Issue.11 , pp. 2657-2666
    • Rodefer, J.S.1    Nguyen, T.N.2    Karlsson, J.J.3    Arnt, J.4
  • 63
    • 24944520099 scopus 로고    scopus 로고
    • Phosphodiesterase inhibitors for cognitive enhancement
    • DOI 10.2174/138161205774370799
    • G.M. Rose, A. Hopper, M. De Vivo, and A. Tehim Phosphodiesterase inhibitors for cognitive enhancement Curr. Pharm. Des. 11 26 2005 3329 3334 (Pubitemid 41300762)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.26 , pp. 3329-3334
    • Rose, G.M.1    Hopper, A.2    De Vivo, M.3    Tehim, A.4
  • 64
    • 24344434746 scopus 로고    scopus 로고
    • The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP Levels in hippocampal slices
    • DOI 10.1016/j.bbr.2005.04.021, PII S0166432805002378
    • K. Rutten, J.D. Vente, A. Sik, M.M. Ittersum, J. Prickaerts, and A. Blokland The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP levels in hippocampal slices Behav. Brain Res. 164 1 2005 Oct 14 11 16 (Pubitemid 41253727)
    • (2005) Behavioural Brain Research , vol.164 , Issue.1 , pp. 11-16
    • Rutten, K.1    De Vente, J.2    Sik, A.3    Markerink-Van Ittersum, M.4    Prickaerts, J.5    Blokland, A.6
  • 65
    • 33847305401 scopus 로고    scopus 로고
    • Time-dependent involvement of cAMP and cGMP in consolidation of object memory: Studies using selective phosphodiesterase type 2, 4 and 5 inhibitors
    • DOI 10.1016/j.ejphar.2006.11.041, PII S001429990601329X
    • K. Rutten, J. Prickaerts, M. Hendrix, F.J. van der Staay, A. Sik, and A. Blokland Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors Eur. J. Pharmacol. 558 1-3 2007 Mar 8 107 112 (Pubitemid 46328881)
    • (2007) European Journal of Pharmacology , vol.558 , Issue.1-3 , pp. 107-112
    • Rutten, K.1    Prickaerts, J.2    Hendrix, M.3    Van Der Staay, F.J.4    Sik, A.5    Blokland, A.6
  • 66
    • 34247596903 scopus 로고    scopus 로고
    • The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat
    • DOI 10.1007/s00213-006-0697-4
    • K. Rutten, C. Lieben, L. Smits, and A. Blokland The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat Psychopharmacology (Berl.) 192 2007 275 282 (Pubitemid 46669202)
    • (2007) Psychopharmacology , vol.192 , Issue.2 , pp. 275-282
    • Rutten, K.1    Lieben, C.2    Smits, L.3    Blokland, A.4
  • 67
    • 43049118254 scopus 로고    scopus 로고
    • Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques
    • K. Rutten, J.L. Basile, J. Prickaerts, A. Blokland, and J.A. Vivian Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques Psychopharmacology (Berl.) 196 2008 643 648
    • (2008) Psychopharmacology (Berl.) , vol.196 , pp. 643-648
    • Rutten, K.1    Basile, J.L.2    Prickaerts, J.3    Blokland, A.4    Vivian, J.A.5
  • 68
    • 51349119980 scopus 로고    scopus 로고
    • Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats
    • K. Rutten, J. Prickaerts, G. Schaenzle, H. Rosenbrock, and A. Blokland Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats Neurobiol. Learn. Mem. 90 2008 569 575
    • (2008) Neurobiol. Learn. Mem. , vol.90 , pp. 569-575
    • Rutten, K.1    Prickaerts, J.2    Schaenzle, G.3    Rosenbrock, H.4    Blokland, A.5
  • 70
    • 0031800004 scopus 로고    scopus 로고
    • Effects of continuous D-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats
    • DOI 10.1016/S0893-133X(97)00200-5, PII S0893133X97002005
    • F. Sams-Dodd Effects of continuous d-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats Neuropsychopharmacology 19 1 1998 Jul 18 25 (Pubitemid 28255210)
    • (1998) Neuropsychopharmacology , vol.19 , Issue.1 , pp. 18-25
    • Sams-Dodd, F.1
  • 72
    • 0035257844 scopus 로고    scopus 로고
    • Central effects of sildenafil (Viagra) on auditory selective attention and verbal recognition memory in humans: A study with event-related brain potentials
    • D. Schultheiss, S.V. Müller, W. Nager, C.G. Stief, N. Schlote, U. Jonas, C. Asvestis, S. Johannes, and T.F. Münte Central effects of sildenafil (Viagra) on auditory selective attention and verbal recognition memory in humans: a study with event-related brain potentials World J. Urol. 19 1 2001 Feb 46 50 (Pubitemid 33777032)
    • (2001) World Journal of Urology , vol.19 , Issue.1 , pp. 46-50
    • Schultheiss, D.1
  • 74
    • 0037403722 scopus 로고    scopus 로고
    • Postnatal phencyclidine-induced deficit in adult water maze performance is associated with N-methyl-D-aspartate receptor upregulation
    • DOI 10.1016/S0736-5748(03)00026-1
    • R. Sircar Postnatal phencyclidine-induced deficit in adult water maze performance is associated with N-methyl-d-aspartate receptor upregulation Int. J. Dev. Neurosci. 21 3 2003 May 159 167 (Pubitemid 36444541)
    • (2003) International Journal of Developmental Neuroscience , vol.21 , Issue.3 , pp. 159-167
    • Sircar, R.1
  • 77
    • 38149121389 scopus 로고    scopus 로고
    • Behavioral characterization of mice deficient in the phosphodiesterase- 10A (PDE10A) enzyme on a C57/Bl6N congenic background
    • J.A. Siuciak, S.A. McCarthy, D.S. Chapin, A.N. Martin, J.F. Harms, and C.J. Schmidt Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background Neuropharmacology 54 2008 417 427
    • (2008) Neuropharmacology , vol.54 , pp. 417-427
    • Siuciak, J.A.1    McCarthy, S.A.2    Chapin, D.S.3    Martin, A.N.4    Harms, J.F.5    Schmidt, C.J.6
  • 78
    • 0014336285 scopus 로고
    • A comparison of psychological and psychophysical test patterns before and after receiving papaverine HCL
    • W.L. Smith, M.J. Philippus, and J.B. Lowrey A comparison of psychological and psychophysical test patterns before and after receiving papaverine HCL Curr. Ther. Res. Clin. Exp. 10 9 1968 428 431
    • (1968) Curr. Ther. Res. Clin. Exp. , vol.10 , Issue.9 , pp. 428-431
    • Smith, W.L.1    Philippus, M.J.2    Lowrey, J.B.3
  • 79
    • 7644242976 scopus 로고    scopus 로고
    • Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
    • DOI 10.1161/01.STR.0000144682.00822.83
    • W.S. Smith, C.F. Dowd, S.C. Johnston, N.U. Ko, S.J. DeArmond, and W.P. Dillon Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage Stroke 35 11 2004 2518 2522 (Pubitemid 39458410)
    • (2004) Stroke , vol.35 , Issue.11 , pp. 2518-2522
    • Smith, W.S.1    Dowd, C.F.2    Johnston, S.C.3    Ko, N.U.4    DeArmond, S.J.5    Dillon, W.P.6    Setty, D.7    Lawton, M.T.8    Young, W.L.9    Higashida, R.T.10    Halbach, V.V.11
  • 80
    • 0034009080 scopus 로고    scopus 로고
    • Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
    • DOI 10.1016/S0955-0674(99)00073-3
    • S.H. Soderling, and J.A. Beavo Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions Curr. Opin. Cell Biol. 12 2 2000 174 179 (Pubitemid 30142563)
    • (2000) Current Opinion in Cell Biology , vol.12 , Issue.2 , pp. 174-179
    • Soderling, S.H.1    Beavo, J.A.2
  • 81
    • 0014807764 scopus 로고
    • Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride
    • F.H. Stern Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride J. Am. Geriatr. Soc. 18 6 1970 507 512
    • (1970) J. Am. Geriatr. Soc. , vol.18 , Issue.6 , pp. 507-512
    • Stern, F.H.1
  • 82
    • 18344395117 scopus 로고    scopus 로고
    • Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: Studies using heterologous expression systems of the dopamine transporter
    • DOI 10.1016/S0006-2952(01)00922-4, PII S0006295201009224
    • A. Storch, S. Ott, Y.I. Hwang, R. Ortmann, A. Hein, and S. Frenzel Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter Biochem. Pharmacol. 63 5 2002 909 920 (Pubitemid 34243004)
    • (2002) Biochemical Pharmacology , vol.63 , Issue.5 , pp. 909-920
    • Storch, A.1    Ott, S.2    Hwang, Y.-I.3    Ortmann, R.4    Hein, A.5    Frenzel, S.6    Matsubara, K.7    Ohta, S.8    Wolf, H.-U.9    Schwarz, J.10
  • 84
    • 34347381910 scopus 로고    scopus 로고
    • Differential course of executive control changes during normal aging
    • DOI 10.1080/13825580600678442, PII 779748552
    • F.H. Treitz, K. Heyder, and I. Daum Differential course of executive control changes during normal aging Neuropsychol. Dev. Cogn. B. Aging Neuropsychol. Cogn. 14 4 2007 370 393 (Pubitemid 47027108)
    • (2007) Aging, Neuropsychology, and Cognition , vol.14 , Issue.4 , pp. 370-393
    • Treitz, F.H.1    Heyder, K.2    Daum, I.3
  • 85
    • 0032100464 scopus 로고    scopus 로고
    • The delayed effects of phencyclidine (PCP) disrupt latent inhibition in a conditioned taste aversion paradigm
    • DOI 10.1016/S0091-3057(98)00026-4, PII S0091305798000264
    • S.M. Turgeon, E.A. Auerbach, and M.A. Heller The delayed effects of phencyclidine (PCP) disrupt latent inhibition in a conditioned taste aversion paradigm Pharmacol. Biochem. Behav. 60 2 1998 Jun 553 558 (Pubitemid 28282698)
    • (1998) Pharmacology Biochemistry and Behavior , vol.60 , Issue.2 , pp. 553-558
    • Turgeon, S.M.1    Auerbach, E.A.2    Heller, M.A.3
  • 86
    • 2342630520 scopus 로고    scopus 로고
    • Species differences in the localization of cGMP-producing and NO-responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry
    • DOI 10.1111/j.0953-816X.2004.03327.x
    • W.C. van Staveren, H.W. Steinbusch, M. Markerink-van Ittersum, S. Behrends, and J. de Vente Species differences in the localization of cGMP-producing and NO-responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry Eur. J. Neurosci. 19 8 2004 Apr 2155 2168 (Pubitemid 38582204)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.8 , pp. 2155-2168
    • Van Staveren, W.C.G.1    Steinbusch, H.W.M.2    Markerink-van Ittersum, M.3    Behrends, S.4    De Vente, J.5
  • 87
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • O.V. Vitolo, A. Sant'Angelo, V. Costanzo, F. Battaglia, O. Arancio, and M. Shelanski Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling Proc. Natl. Acad. Sci. U S A 99 20 2002 13217 13221
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , Issue.20 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 89
    • 14544280630 scopus 로고    scopus 로고
    • High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients
    • DOI 10.1038/sj.ijir.3901283
    • J.L. Weeks, R. Zoraghi, A. Beasley, K.R. Sekhar, S.H. Francis, and J.D. Corbin High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients Int. J. Impot Res. 17 1 2005 Jan-Feb 5 9 (Pubitemid 40299987)
    • (2005) International Journal of Impotence Research , vol.17 , Issue.1 , pp. 5-9
    • Weeks II, J.L.1    Zoraghi, R.2    Beasley, A.3    Sekhar, K.R.4    Francis, S.H.5    Corbin, J.D.6
  • 92
    • 0033922848 scopus 로고    scopus 로고
    • Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats
    • DOI 10.1007/s002130000414
    • H.T. Zhang, and J.M. O'Donnell Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats Psychopharmacology (Berl.) 150 3 2000 Jun 311 316 (Pubitemid 30447851)
    • (2000) Psychopharmacology , vol.150 , Issue.3 , pp. 311-316
    • Zhang, H.-T.1    O'Donnell, J.M.2
  • 93
    • 0034051217 scopus 로고    scopus 로고
    • Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism
    • DOI 10.1016/S0893-133X(00)00108-1, PII S0893133X00001081
    • H.T. Zhang, A.M. Crissman, N.R. Dorairaj, L.J. Chandler, and J.M. O'Donnell Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism Neuropsychopharmacology 23 2 2000 Aug 198 204 (Pubitemid 30406904)
    • (2000) Neuropsychopharmacology , vol.23 , Issue.2 , pp. 198-204
    • Zhang, H.-T.1    Crissman, A.M.2    Dorairaj, N.R.3    Chandler, L.J.4    O'Donnell, J.M.5
  • 94
    • 3242758203 scopus 로고    scopus 로고
    • Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus
    • DOI 10.1038/sj.npp.1300440
    • H.T. Zhang, Y. Zhao, Y. Huang, N.R. Dorairaj, L.J. Chandler, and J.M. ODonnell Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus Neuropsychopharmacology 29 2004 1432 1439 (Pubitemid 38982235)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.8 , pp. 1432-1439
    • Zhang, H.-T.1    Zhao, Y.2    Huang, Y.3    Dorairaj, N.R.4    Chandler, L.J.5    O'Donnell, J.M.6
  • 95
    • 25844486653 scopus 로고    scopus 로고
    • Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats
    • DOI 10.1007/s00213-005-0055-y
    • H.T. Zhang, Y. Huang, K. Mishler, S.C. Roerig, and J.M. O'Donnell Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats Psychopharmacology (Berl.) 182 1 2005 Oct 104 115 (Pubitemid 41400867)
    • (2005) Psychopharmacology , vol.182 , Issue.1 , pp. 104-115
    • Zhang, H.-T.1    Huang, Y.2    Mishler, K.3    Roerig, S.C.4    O'Donnell, J.M.5
  • 96
    • 77749309302 scopus 로고    scopus 로고
    • Phosphodiesterase targets for cognitive dysfunction and schizophrenia-a New York Academy of Sciences Meeting
    • H.T. Zhang Phosphodiesterase targets for cognitive dysfunction and schizophrenia-a New York Academy of Sciences Meeting IDrugs 13 3 2010 Mar 166 168
    • (2010) IDrugs , vol.13 , Issue.3 , pp. 166-168
    • Zhang, H.T.1
  • 97
    • 0028275855 scopus 로고
    • Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
    • DOI 10.1038/368635a0
    • M. Zhuo, Y. Hu, C. Schultz, E.R. Kandel, and R.D. Hawkins Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation Nature 368 6472 1994 Apr 14 635 639 (Pubitemid 24153387)
    • (1994) Nature , vol.368 , Issue.6472 , pp. 635-639
    • Zhuo, M.1    Hu, Y.2    Schultz, C.3    Kandel, E.R.4    Hawkins, R.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.