Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism

Neuropsychopharmacology

Volumn 23, Issue 2, 2000, Pages 198-204

  Zhang, Han Ting ^a   Crissman, Alicia M ^a   Dorairaj, Nandakumar R ^a   Chandler, L Judson ^b   O'Donnell, James M ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cyclic AMP; Memory; MK 801; NMDA receptor; Phosphodiesterase; Rolipram

Indexed keywords

CYCLIC AMP; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM;

AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; MAZE TEST; MEMORY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WORKING MEMORY;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; AVOIDANCE LEARNING; CELLS, CULTURED; CYCLIC AMP; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MAZE LEARNING; MEMORY DISORDERS; N-METHYLASPARTATE; NEURONS; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; ROLIPRAM;

EID: 0034051217     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(00)00108-1     Document Type: Article

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