The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging

Brain Research

Volumn 1216, Issue , 2008, Pages 68-77

  Domek Lopacinska K ^a   Strosznajder, J B ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Cyclic; GMP; Learning; Memory; Nitric; oxide synthase; Phosphodiesterases

Indexed keywords

BAYER 607750; CYCLIC GMP PHOSPHODIESTERASE; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE V; SPLEEN EXONUCLEASE; ZAPRINAST; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 2; NOOTROPIC AGENT; PURINE DERIVATIVE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; LEARNING; LOCOMOTION; MALE; MEMORY; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RADIOCHEMISTRY; RAT; RECOGNITION; ANIMAL; BRAIN; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EXPLORATORY BEHAVIOR; METABOLISM; MOTOR ACTIVITY; NEOSTRIATUM; PHYSIOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

AGING; ANIMALS; BRAIN; CEREBRAL CORTEX; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 5; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; MALE; MOTOR ACTIVITY; NEOSTRIATUM; NITRIC OXIDE SYNTHASE; NOOTROPIC AGENTS; PHOSPHODIESTERASE INHIBITORS; PURINONES; RATS; RATS, WISTAR; RECOGNITION (PSYCHOLOGY);

EID: 46549084175     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.02.108     Document Type: Article

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