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Volumn 49, Issue 2, 2011, Pages 198-208

G-quadruplexes: From guanine gels to chemotherapeutics

Author keywords

G quadruplex; G quartet; Guanosine; Telomerase; Telomere

Indexed keywords

G-QUADRUPLEXES; G-QUARTET; GUANOSINES; TELOMERASE; TELOMERES;

EID: 84855996113     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-011-9395-5     Document Type: Review
Times cited : (72)

References (138)
  • 1
    • 1042274320 scopus 로고
    • Untersuchungen über die Guanylsäure
    • Bang, I. (1910). Untersuchungen über die Guanylsäure. Biochemische Zeitschrift, 26, 293-311.
    • (1910) Biochemische Zeitschrift , vol.26 , pp. 293-311
    • Bang, I.1
  • 5
    • 0023663911 scopus 로고
    • Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs
    • Henderson, E., Hardin, C. C., Walk, S. K., Tinoco, I., Jr., & Blackburn, E. H. (1987). Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs. Cell, 51, 899-908.
    • (1987) Cell , vol.51 , pp. 899-908
    • Henderson, E.1    Hardin, C.C.2    Walk, S.K.3    Tinoco Jr., I.4    Blackburn, E.H.5
  • 6
    • 0023788886 scopus 로고
    • Formation of parallel fourstranded complexes by guanine-rich motifs in DNA and its implications for meiosis
    • Sen, D., & Gilbert, W. (1988). Formation of parallel fourstranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature, 334, 364-366.
    • (1988) Nature , vol.334 , pp. 364-366
    • Sen, D.1    Gilbert, W.2
  • 7
    • 0024843757 scopus 로고
    • Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
    • DOI 10.1038/342825a0
    • Sundquist, W. I., & Klug, A. (1989). Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature, 342, 825-829. (Pubitemid 20023821)
    • (1989) Nature , vol.342 , Issue.6251 , pp. 825-829
    • Sundquist, W.I.1    Klug, A.2
  • 8
    • 0024787884 scopus 로고
    • Monovalent cation-induced structure of telomeric DNA: The G-quartet model
    • DOI 10.1016/0092-8674(89)90610-7
    • Williamson, J. R., Raghuraman, M. K., & Cech, T. R. (1989). Monovalent cation-induced structure of telomeric DNA: The G-quartet model. Cell, 59, 871-880. (Pubitemid 20022377)
    • (1989) Cell , vol.59 , Issue.5 , pp. 871-880
    • Williamson, J.R.1    Raghuraman, M.K.2    Cech, T.R.3
  • 9
    • 0004497012 scopus 로고
    • Physicochemical properties of nucleosides 3. Gel formation by 8-bromoguanosine
    • Chantot, J., & Guschlbauer, W. (1969). Physicochemical properties of nucleosides 3. Gel formation by 8-bromoguanosine. FEBS Letter, 4, 173-176.
    • (1969) FEBS Letter , vol.4 , pp. 173-176
    • Chantot, J.1    Guschlbauer, W.2
  • 11
    • 0029071176 scopus 로고
    • A phase diagram for sodium and potassium ion control of polymorphism in telomeric DNA
    • Miura, T., Benevides, J. M., & Thomas, G. J., Jr. (1995). A phase diagram for sodium and potassium ion control of polymorphism in telomeric DNA. Journal of Molecular Biology, 248, 233-238.
    • (1995) Journal of Molecular Biology , vol.248 , pp. 233-238
    • Miura, T.1    Benevides, J.M.2    Thomas Jr., G.J.3
  • 13
    • 33644865847 scopus 로고    scopus 로고
    • Extension of G-quadruplex DNA by ciliate telomerase
    • DOI 10.1038/sj.emboj.7601006, PII 7601006
    • Oganesian, L., Moon, I. K., Bryan, T. M., & Jarstfer, M. B. (2006). Extension of G-quadruplex DNA by ciliate telomerase. EMBO Journal, 25, 1148-1159. (Pubitemid 43372127)
    • (2006) EMBO Journal , vol.25 , Issue.5 , pp. 1148-1159
    • Oganesian, L.1    Moon, I.K.2    Bryan, T.M.3    Jarstfer, M.B.4
  • 14
    • 0345098322 scopus 로고    scopus 로고
    • Two-Repeat Human Telomeric d(TAGGGTTAGGGT) Sequence Forms Interconverting Parallel and Antiparallel G-Quadruplexes in Solution: Distinct Topologies, Thermodynamic Properties, and Folding/Unfolding Kinetics
    • DOI 10.1021/ja037616j
    • Phan, A. T., & Patel, D. J. (2003). Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: Distinct topologies, thermodynamic properties, and folding/unfolding kinetics. Journal of the American Chemical Society, 125, 15021-15027. (Pubitemid 37509665)
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.49 , pp. 15021-15027
    • Phan, A.T.1    Patel, D.J.2
  • 15
    • 0028773155 scopus 로고
    • Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG)
    • Schultze, P., Smith, F. W., & Feigon, J. (1994). Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG). Structure, 2, 221-233.
    • (1994) Structure , vol.2 , pp. 221-233
    • Schultze, P.1    Smith, F.W.2    Feigon, J.3
  • 17
    • 0344304471 scopus 로고    scopus 로고
    • Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer
    • DOI 10.1073/pnas.2433350100
    • Ying, L., Green, J. J., Li, H., Klenerman, D., & Balasubramanian, S. (2003). Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proceedings of National Academy of Science of the United States of America, 100, 14629-14634. (Pubitemid 37517941)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.25 , pp. 14629-14634
    • Ying, L.1    Green, J.J.2    Li, H.3    Klenerman, D.4    Balasubramanian, S.5
  • 18
    • 77955834763 scopus 로고    scopus 로고
    • Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence
    • Dailey, M. M., Miller, M. C., Bates, P. J., Lane, A. N., & Trent, J. O. (2010). Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence. Nucleic Acids Research, 38, 4877-4888.
    • (2010) Nucleic Acids Research , vol.38 , pp. 4877-4888
    • Dailey, M.M.1    Miller, M.C.2    Bates, P.J.3    Lane, A.N.4    Trent, J.O.5
  • 19
    • 0001505226 scopus 로고    scopus 로고
    • Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids
    • DOI 10.1002/1097-0282(2000/2001)56:3<147::AID-BIP10011>3.0.CO;2-N
    • Hardin, C. C., Perry, A. G., & White, K. (2000). Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids. Biopolymers, 56, 147-194. (Pubitemid 33115750)
    • (2000) Biopolymers , vol.56 , Issue.3 , pp. 147-194
    • Hardin, C.C.1    Perry, A.G.2    White, K.3
  • 20
    • 38849085810 scopus 로고    scopus 로고
    • A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadraplexes
    • DOI 10.1021/bi701873c
    • Bugaut, A., & Balasubramanian, S. (2008). A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry, 47, 689-697. (Pubitemid 351195440)
    • (2008) Biochemistry , vol.47 , Issue.2 , pp. 689-697
    • Bugaut, A.1    Balasubramanian, S.2
  • 21
    • 78649850820 scopus 로고    scopus 로고
    • How long is too long? Effects of loop size on G-quadruplex stability
    • Guedin, A., Gros, J., Alberti, P., & Mergny, J. L. (2010). How long is too long? Effects of loop size on G-quadruplex stability. Nucleic Acids Research, 38, 7858-7868.
    • (2010) Nucleic Acids Research , vol.38 , pp. 7858-7868
    • Guedin, A.1    Gros, J.2    Alberti, P.3    Mergny, J.L.4
  • 23
    • 34547117416 scopus 로고    scopus 로고
    • 4 sequence with complementary strand in close vicinity under molecularly crowded condition
    • DOI 10.1093/nar/gkm203
    • Kan, Z. Y., Lin, Y., Wang, F., Zhuang, X. Y., Zhao, Y., Pang, D. W., et al. (2007). G-quadruplex formation in human telomeric (TTAGGG)4 sequence with complementary strand in close vicinity under molecularly crowded condition. Nucleic Acids Research, 35, 3646-3653. (Pubitemid 47244659)
    • (2007) Nucleic Acids Research , vol.35 , Issue.11 , pp. 3646-3653
    • Kan, Z.-Y.1    Lin, Y.2    Wang, F.3    Zhuang, X.-Y.4    Zhao, Y.5    Pang, D.-W.6    Hao, Y.-H.7    Tan, Z.8
  • 26
    • 0027750779 scopus 로고
    • Solution structure of a parallel-stranded G-quadruplex DNA
    • DOI 10.1006/jmbi.1993.1668
    • Wang, Y., & Patel, D. J. (1993). Solution structure of a parallelstranded G-quadruplex DNA. Journal of Molecular Biology, 234, 1171-1183. (Pubitemid 24027245)
    • (1993) Journal of Molecular Biology , vol.234 , Issue.4 , pp. 1171-1183
    • Wang, Y.1    Patel, D.J.2
  • 27
    • 0037142071 scopus 로고    scopus 로고
    • Crystal structure of parallel quadruplexes from human telomeric DNA
    • DOI 10.1038/nature755
    • Parkinson, G. N., Lee, M. P., & Neidle, S. (2002). Crystal structure of parallel quadruplexes from human telomeric DNA. Nature, 417, 876-880. (Pubitemid 34670337)
    • (2002) Nature , vol.417 , Issue.6891 , pp. 876-880
    • Parkinson, G.N.1    Lee, M.P.H.2    Neidle, S.3
  • 28
    • 33646943863 scopus 로고    scopus 로고
    • Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
    • DOI 10.1093/nar/gkl348
    • Ambrus, A., Chen, D., Dai, J., Bialis, T., Jones, R. A., & Yang, D. (2006). Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/ antiparallel strands in potassium solution. Nucleic Acids Research, 34, 2723-2735. (Pubitemid 43985634)
    • (2006) Nucleic Acids Research , vol.34 , Issue.9 , pp. 2723-2735
    • Ambrus, A.1    Chen, D.2    Dai, J.3    Bialis, T.4    Jones, R.A.5    Yang, D.6
  • 29
    • 33746600695 scopus 로고    scopus 로고
    • + solution: An intramolecular (3 + 1) G-quadruplex scaffold
    • DOI 10.1021/ja062791w
    • Luu, K. N., Phan, A. T., Kuryavyi, V., Lacroix, L., & Patel, D. J. (2006). Structure of the human telomere in K+ solution: An intramolecular (3 + 1) G-quadruplex scaffold. Journal of the American Chemical Society, 128, 9963-9970. (Pubitemid 44147983)
    • (2006) Journal of the American Chemical Society , vol.128 , Issue.30 , pp. 9963-9970
    • Luu, K.N.1    Phan, A.T.2    Kuryavyi, V.3    Lacroix, L.4    Patel, D.J.5
  • 30
    • 33750970018 scopus 로고    scopus 로고
    • + solution
    • DOI 10.1093/nar/gkl726
    • Phan, A. T., Luu, K. N., & Patel, D. J. (2006). Different loop arrangements of intramolecular human telomeric (3 + 1) G-quadruplexes in K+ solution. Nucleic Acids Research, 34, 5715-5719. (Pubitemid 44742458)
    • (2006) Nucleic Acids Research , vol.34 , Issue.19 , pp. 5715-5719
    • Phan, A.T.1    Luu, K.N.2    Patel, D.J.3
  • 31
    • 33745612968 scopus 로고    scopus 로고
    • + solution
    • DOI 10.1016/j.bmc.2006.04.033, PII S0968089606003002
    • Xu, Y., Noguchi, Y., & Sugiyama, H. (2006). The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution. Bioorganic and Medicinal Chemistry, 14, 5584-5591. (Pubitemid 43994462)
    • (2006) Bioorganic and Medicinal Chemistry , vol.14 , Issue.16 , pp. 5584-5591
    • Xu, Y.1    Noguchi, Y.2    Sugiyama, H.3
  • 32
    • 34548550548 scopus 로고    scopus 로고
    • + solution: Insights into structure polymorphism of the human telomeric sequence
    • DOI 10.1093/nar/gkm522
    • Dai, J., Carver, M., Punchihewa, C., Jones, R. A., & Yang, D. (2007). Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: Insights into structure polymorphism of the human telomeric sequence. Nucleic Acids Research, 35, 4927-4940. (Pubitemid 47394180)
    • (2007) Nucleic Acids Research , vol.35 , Issue.15 , pp. 4927-4940
    • Dai, J.1    Carver, M.2    Punchihewa, C.3    Jones, R.A.4    Yang, D.5
  • 33
    • 36148991081 scopus 로고    scopus 로고
    • + solution
    • DOI 10.1093/nar/gkm706
    • Phan, A. T., Kuryavyi, V., Luu, K. N., & Patel, D. J. (2007). Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Research, 35, 6517-6525. (Pubitemid 350111619)
    • (2007) Nucleic Acids Research , vol.35 , Issue.19 , pp. 6517-6525
    • Phan, A.T.1    Kuryavyi, V.2    Luu, K.N.3    Patel, D.J.4
  • 34
    • 67749124298 scopus 로고    scopus 로고
    • + solution: A stable basket-type G-quadruplex with only two G-tetrad layers
    • Lim, K. W., Amrane, S., Bouaziz, S., Xu, W., Mu, Y., Patel, D. J., et al. (2009). Structure of the human telomere in K+ solution: A stable basket-type G-quadruplex with only two G-tetrad layers. Journal of the American Chemical Society, 131, 4301-4309.
    • (2009) Journal of the American Chemical Society , vol.131 , pp. 4301-4309
    • Lim, K.W.1    Amrane, S.2    Bouaziz, S.3    Xu, W.4    Mu, Y.5    Patel, D.J.6
  • 36
    • 34548762534 scopus 로고    scopus 로고
    • + solution under molecular crowding condition
    • DOI 10.1021/ja0730462
    • Xue, Y., Kan, Z. Y., Wang, Q., Yao, Y., Liu, J., Hao, Y. H., et al. (2007). Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition. Journal of the American Chemical Society, 129, 11185-11191. (Pubitemid 47435722)
    • (2007) Journal of the American Chemical Society , vol.129 , Issue.36 , pp. 11185-11191
    • Xue, Y.1    Kan, Z.-Y.2    Wang, Q.3    Yao, Y.4    Liu, J.5    Hao, Y.-H.6    Tan, Z.7
  • 37
    • 46049096922 scopus 로고    scopus 로고
    • The structural transition and compaction of human telomeric G-quadruplex induced by excluded volume effect under cation-deficient conditions
    • Zhou, J., Wei, C., Jia, G., Wang, X., Tang, Q., Feng, Z., et al. (2008). The structural transition and compaction of human telomeric G-quadruplex induced by excluded volume effect under cation-deficient conditions. Biophysical Chemistry, 136, 124-127.
    • (2008) Biophysical Chemistry , vol.136 , pp. 124-127
    • Zhou, J.1    Wei, C.2    Jia, G.3    Wang, X.4    Tang, Q.5    Feng, Z.6
  • 38
    • 78650109518 scopus 로고    scopus 로고
    • Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 30 sequence of d(AG 3(TTAG3)3)
    • Miller, M. C., Buscaglia, R., Chaires, J. B., Lane, A. N., & Trent, J. O. (2010). Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 30 sequence of d(AG 3(TTAG3)3). Journal of the American Chemical Society, 132, 17105-17107.
    • (2010) Journal of the American Chemical Society , vol.132 , pp. 17105-17107
    • Miller, M.C.1    Buscaglia, R.2    Chaires, J.B.3    Lane, A.N.4    Trent, J.O.5
  • 39
    • 31544466516 scopus 로고    scopus 로고
    • Human telomeres have different overhang sizes at leading versus lagging strands
    • DOI 10.1016/j.molcel.2005.12.004, PII S1097276505018460
    • Chai, W., Du, Q., Shay, J. W., & Wright, W. E. (2006). Human telomeres have different overhang sizes at leading versus lagging strands. Molecular Cell, 21, 427-435. (Pubitemid 43163537)
    • (2006) Molecular Cell , vol.21 , Issue.3 , pp. 427-435
    • Chai, W.1    Du, Q.2    Shay, J.W.3    Wright, W.E.4
  • 40
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • DOI 10.1016/S0092-8674(00)81908-X
    • Makarov, V. L., Hirose, Y., & Langmore, J. P. (1997). Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88, 657-666. (Pubitemid 27152408)
    • (1997) Cell , vol.88 , Issue.5 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 41
    • 0030982721 scopus 로고    scopus 로고
    • The terminal DNA structure of mammalian chromosomes
    • DOI 10.1093/emboj/16.12.3705
    • McElligott, R., & Wellinger, R. J. (1997). The terminal DNA structure of mammalian chromosomes. EMBO Journal, 16, 3705-3714. (Pubitemid 27250063)
    • (1997) EMBO Journal , vol.16 , Issue.12 , pp. 3705-3714
    • McElligott, R.1    Wellinger, R.J.2
  • 42
    • 0030731928 scopus 로고    scopus 로고
    • Normal human chromosomes have long G-rich telomeric overhangs at one end
    • Wright, W. E., Tesmer, V. M., Huffman, K. E., Levene, S. D., & Shay, J. W. (1997). Normal human chromosomes have long G-rich telomeric overhangs at one end. Genes and Development, 11, 2801-2809. (Pubitemid 27481681)
    • (1997) Genes and Development , vol.11 , Issue.21 , pp. 2801-2809
    • Wright, W.E.1    Tesmer, V.M.2    Huffman, K.E.3    Levene, S.D.4    Shay, J.W.5
  • 43
    • 33845294453 scopus 로고    scopus 로고
    • Characterization of structure and stability of long telomeric DNA G-quadruplexes
    • DOI 10.1021/ja064536h
    • Yu, H. Q., Miyoshi, D., & Sugimoto, N. (2006). Characterization of structure and stability of long telomeric DNA G-quadruplexes. Journal of the American Chemical Society, 128, 15461-15468. (Pubitemid 44876022)
    • (2006) Journal of the American Chemical Society , vol.128 , Issue.48 , pp. 15461-15468
    • Yu, H.-Q.1    Miyoshi, D.2    Sugimoto, N.3
  • 44
    • 70349661733 scopus 로고    scopus 로고
    • Consecutive formation of G-quadruplexes in human telomeric- overhang DNA: A protective capping structure for telomere ends
    • Xu, Y., Ishizuka, T., Kurabayashi, K., & Komiyama, M. (2009). Consecutive formation of G-quadruplexes in human telomeric- overhang DNA: A protective capping structure for telomere ends. Angewandte Chemie, 48, 7833-7836.
    • (2009) Angewandte Chemie , vol.48 , pp. 7833-7836
    • Xu, Y.1    Ishizuka, T.2    Kurabayashi, K.3    Komiyama, M.4
  • 46
    • 20144364292 scopus 로고    scopus 로고
    • Prevalence of quadruplexes in the human genome
    • DOI 10.1093/nar/gki609
    • Huppert, J. L., & Balasubramanian, S. (2005). Prevalence of quadruplexes in the human genome. Nucleic Acids Research, 33, 2908-2916. (Pubitemid 41511230)
    • (2005) Nucleic Acids Research , vol.33 , Issue.9 , pp. 2908-2916
    • Huppert, J.L.1    Balasubramanian, S.2
  • 47
    • 20144369806 scopus 로고    scopus 로고
    • Highly prevalent putative quadruplex sequence motifs in human DNA
    • DOI 10.1093/nar/gki553
    • Todd, A. K., Johnston, M., & Neidle, S. (2005). Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Research, 33, 2901-2907. (Pubitemid 41511229)
    • (2005) Nucleic Acids Research , vol.33 , Issue.9 , pp. 2901-2907
    • Todd, A.K.1    Johnston, M.2    Neidle, S.3
  • 48
    • 3042671689 scopus 로고    scopus 로고
    • Influence of loop size on the stability of intramolecular DNA quadruplexes
    • DOI 10.1093/nar/gkh598
    • Risitano, A., & Fox, K. R. (2004). Influence of loop size on the stability of intramolecular DNA quadruplexes. Nucleic Acids Research, 32, 2598-2606. (Pubitemid 38854813)
    • (2004) Nucleic Acids Research , vol.32 , Issue.8 , pp. 2598-2606
    • Risitano, A.1    Fox, K.R.2
  • 49
    • 33748519569 scopus 로고    scopus 로고
    • Gene function correlates with potential for G4 DNA formation in the human genome
    • DOI 10.1093/nar/gkl529
    • Eddy, J., & Maizels, N. (2006). Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Research, 34, 3887-3896. (Pubitemid 44391004)
    • (2006) Nucleic Acids Research , vol.34 , Issue.14 , pp. 3887-3896
    • Eddy, J.1    Maizels, N.2
  • 50
    • 33846928449 scopus 로고    scopus 로고
    • G-quadruplexes in promoters throughout the human genome
    • DOI 10.1093/nar/gkl1057
    • Huppert, J. L., & Balasubramanian, S. (2007). G-quadruplexes in promoters throughout the human genome. Nucleic Acids Research, 35, 406-413. (Pubitemid 46232058)
    • (2007) Nucleic Acids Research , vol.35 , Issue.2 , pp. 406-413
    • Huppert, J.L.1    Balasubramanian, S.2
  • 51
    • 40249084264 scopus 로고    scopus 로고
    • Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes
    • DOI 10.1093/nar/gkm1138
    • Eddy, J.,&Maizels, N. (2008). Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Research, 36, 1321-1333. (Pubitemid 351330947)
    • (2008) Nucleic Acids Research , vol.36 , Issue.4 , pp. 1321-1333
    • Eddy, J.1    Maizels, N.2
  • 52
    • 0037015078 scopus 로고    scopus 로고
    • Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
    • DOI 10.1073/pnas.182256799
    • Siddiqui-Jain, A., Grand, C. L., Bearss, D. J., & Hurley, L. H. (2002). Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proceedings of National Academy of Science of the United States of America, 99, 11593-11598. (Pubitemid 34994444)
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , Issue.18 , pp. 11593-11598
    • Siddiqui-Jain, A.1    Grand, C.L.2    Bearss, D.J.3    Hurley, L.H.4
  • 53
    • 69949144600 scopus 로고    scopus 로고
    • Identification and characterization of nucleolin as a c-myc G-quadruplex- binding protein
    • Gonzalez, V., Guo, K., Hurley, L., & Sun, D. (2009). Identification and characterization of nucleolin as a c-myc G-quadruplex- binding protein. The Journal of Biological Chemistry, 284, 23622-23635.
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 23622-23635
    • Gonzalez, V.1    Guo, K.2    Hurley, L.3    Sun, D.4
  • 54
    • 79952344184 scopus 로고    scopus 로고
    • Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene
    • Sun, D., Guo, K., & Shin, Y. J. (2010). Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene. Nucleic Acids Research, 39, 1256-1265.
    • (2010) Nucleic Acids Research , vol.39 , pp. 1256-1265
    • Sun, D.1    Guo, K.2    Shin, Y.J.3
  • 55
    • 0033617316 scopus 로고    scopus 로고
    • Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n
    • Fry, M., & Loeb, L. A. (1999). Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. The Journal of Biological Chemistry, 274, 12797-12802.
    • (1999) The Journal of Biological Chemistry , vol.274 , pp. 12797-12802
    • Fry, M.1    Loeb, L.A.2
  • 56
    • 0037106470 scopus 로고    scopus 로고
    • G4 DNA unwinding by BLM and Sgs1p: Substrate specificity and substrate- specific inhibition
    • Huber, M. D., Lee, D. C., & Maizels, N. (2002). G4 DNA unwinding by BLM and Sgs1p: Substrate specificity and substrate- specific inhibition. Nucleic Acids Research, 30, 3954-3961.
    • (2002) Nucleic Acids Research , vol.30 , pp. 3954-3961
    • Huber, M.D.1    Lee, D.C.2    Maizels, N.3
  • 57
    • 0035393720 scopus 로고    scopus 로고
    • The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
    • Mohaghegh, P., Karow, J. K., Brosh, R. M., Jr, Bohr, V. A., Jr., & Hickson, I. D. (2001). The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Research, 29, 2843-2849. (Pubitemid 32685049)
    • (2001) Nucleic Acids Research , vol.29 , Issue.13 , pp. 2843-2849
    • Mohaghegh, P.1    Karow, J.K.2    Brosh Jr., R.M.3    Bohr, V.A.4    Hickson, I.D.5
  • 58
    • 38349095525 scopus 로고    scopus 로고
    • Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae
    • Hershman, S. G., Chen, Q., Lee, J. Y., Kozak, M. L., Yue, P., Wang, L. S., et al. (2008). Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae. Nucleic Acids Research, 36, 144-156.
    • (2008) Nucleic Acids Research , vol.36 , pp. 144-156
    • Hershman, S.G.1    Chen, Q.2    Lee, J.Y.3    Kozak, M.L.4    Yue, P.5    Wang, L.S.6
  • 59
    • 77950353700 scopus 로고    scopus 로고
    • Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
    • Johnson, J. E., Cao, K., Ryvkin, P., Wang, L. S., & Johnson, F. B. (2010). Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential. Nucleic Acids Research, 38, 1114-1122.
    • (2010) Nucleic Acids Research , vol.38 , pp. 1114-1122
    • Johnson, J.E.1    Cao, K.2    Ryvkin, P.3    Wang, L.S.4    Johnson, F.B.5
  • 61
    • 78649738521 scopus 로고    scopus 로고
    • Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives
    • Micheli, E., Martufi, M., Cacchione, S., De Santis, P., & Savino, M. (2010). Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives. Biophysical Chemistry, 153, 43-53.
    • (2010) Biophysical Chemistry , vol.153 , pp. 43-53
    • Micheli, E.1    Martufi, M.2    Cacchione, S.3    De Santis, P.4    Savino, M.5
  • 62
    • 68249156463 scopus 로고    scopus 로고
    • Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands
    • Palumbo, S. L., Ebbinghaus, S. W., & Hurley, L. H. (2009). Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands. Journal of the American Chemical Society, 131, 10878-10891.
    • (2009) Journal of the American Chemical Society , vol.131 , pp. 10878-10891
    • Palumbo, S.L.1    Ebbinghaus, S.W.2    Hurley, L.H.3
  • 63
    • 0018938790 scopus 로고
    • In vitro aggregation of the gene-sized DNA molecules of the ciliate Stylonychia mytilus
    • DOI 10.1073/pnas.77.7.4104
    • Lipps, H. J. (1980). In vitro aggregation of the gene-sized DNA molecules of the ciliate Stylonychia mytilus. Proceedings of National Academy of Science of the United States of America, 77, 4104-4107. (Pubitemid 10022557)
    • (1980) Proceedings of the National Academy of Sciences of the United States of America , vol.77 , Issue.7 , pp. 4104-4107
    • Lipps, H.J.1
  • 65
    • 4944226977 scopus 로고    scopus 로고
    • A bouquet of chromosomes
    • DOI 10.1242/jcs.01363
    • Harper, L., Golubovskaya, I., & Cande, W. Z. (2004). A bouquet of chromosomes. Journal of Cell Science, 117, 4025-4032. (Pubitemid 39328291)
    • (2004) Journal of Cell Science , vol.117 , Issue.18 , pp. 4025-4032
    • Harper, L.1    Golubovskaya, I.2    Cande, W.Z.3
  • 66
    • 2442506704 scopus 로고    scopus 로고
    • Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets
    • DOI 10.1093/nar/gkh559
    • Anuradha, S., & Muniyappa, K. (2004). Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets. Nucleic Acids Research, 32, 2378-2385. (Pubitemid 38854792)
    • (2004) Nucleic Acids Research , vol.32 , Issue.8 , pp. 2378-2385
    • Anuradha, S.1    Muniyappa, K.2
  • 67
    • 0028243751 scopus 로고
    • The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: Implication of in vivo functions for this novel DNA structure
    • DOI 10.1016/0092-8674(94)90447-2
    • Liu, Z., & Gilbert, W. (1994). The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: Implication of in vivo functions for this novel DNA structure. Cell, 77, 1083-1092. (Pubitemid 24208867)
    • (1994) Cell , vol.77 , Issue.7 , pp. 1083-1092
    • Liu, Z.1    Gilbert, W.2
  • 68
    • 0025877846 scopus 로고
    • Inhibition of telomerase by G-quartet DNA structures
    • Zahler, A. M., Williamson, J. R., Cech, T. R., & Prescott, D. M. (1991). Inhibition of telomerase by G-quartet DNA structures. Nature, 350, 718-720. (Pubitemid 21912306)
    • (1991) Nature , vol.350 , Issue.6320 , pp. 718-720
    • Zahler, A.M.1    Williamson, J.R.2    Cech, T.R.3    Prescott, D.M.4
  • 69
    • 34547120482 scopus 로고    scopus 로고
    • Protection of DNA ends by telomeric 3 G-tail sequences
    • DOI 10.1074/jbc.M702171200
    • Tsai, Y. C., Qi, H., & Liu, L. F. (2007). Protection of DNA ends by telomeric 3' G-tail sequences. The Journal of Biological Chemistry, 282, 18786-18792. (Pubitemid 47100131)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.26 , pp. 18786-18792
    • Tsai, Y.-C.1    Qi, H.2    Liu, L.F.3
  • 70
    • 14844353406 scopus 로고    scopus 로고
    • The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
    • DOI 10.1093/nar/gki257
    • Sacca, B., Lacroix, L., & Mergny, J. L. (2005). The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Research, 33, 1182-1192. (Pubitemid 41439911)
    • (2005) Nucleic Acids Research , vol.33 , Issue.4 , pp. 1182-1192
    • Sacca, B.1    Lacroix, L.2    Mergny, J.-L.3
  • 71
    • 33947310727 scopus 로고    scopus 로고
    • An RNA G-quadruplex in the 5 UTR of the NRAS proto-oncogene modulates translation
    • DOI 10.1038/nchembio864, PII NCHEMBIO864
    • Kumari, S., Bugaut, A., Huppert, J. L., & Balasubramanian, S. (2007). An RNA G-quadruplex in the 5' UTR of the NRAS protooncogene modulates translation. Nature Chemical Biology, 3, 218-221. (Pubitemid 46440536)
    • (2007) Nature Chemical Biology , vol.3 , Issue.4 , pp. 218-221
    • Kumari, S.1    Bugaut, A.2    Huppert, J.L.3    Balasubramanian, S.4
  • 72
    • 38549087401 scopus 로고    scopus 로고
    • GRSDB2 and GRS-UTRdb: Databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAs
    • DOI 10.1093/nar/gkm982
    • Kikin, O., Zappala, Z., D'Antonio, L., & Bagga, P. S. (2008). GRSDB2 and GRS-UTRdb: Databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAs. Nucleic Acids Research, 36, D141-D148. (Pubitemid 351149711)
    • (2008) Nucleic Acids Research , vol.36 , Issue.SUPPL. 1
    • Kikin, O.1    Zappala, Z.2    D'Antonio, L.3    Bagga, P.S.4
  • 73
    • 45749139174 scopus 로고    scopus 로고
    • Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif
    • DOI 10.1261/rna.1001708
    • Arora, A., Dutkiewicz, M., Scaria, V., Hariharan, M., Maiti, S., & Kurreck, J. (2008). Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA, 14, 1290-1296. (Pubitemid 351872187)
    • (2008) RNA , vol.14 , Issue.7 , pp. 1290-1296
    • Arora, A.1    Dutkiewicz, M.2    Scaria, V.3    Hariharan, M.4    Maiti, S.5    Kurreck, J.6
  • 74
    • 73149103952 scopus 로고    scopus 로고
    • Repression of translation of human estrogen receptor alpha by G-quadruplex formation
    • Balkwill, G. D., Derecka, K., Garner, T. P., Hodgman, C., Flint, A. P., & Searle, M. S. (2009). Repression of translation of human estrogen receptor alpha by G-quadruplex formation. Biochemistry, 48, 11487-11495.
    • (2009) Biochemistry , vol.48 , pp. 11487-11495
    • Balkwill, G.D.1    Derecka, K.2    Garner, T.P.3    Hodgman, C.4    Flint, A.P.5    Searle, M.S.6
  • 75
    • 77957058196 scopus 로고    scopus 로고
    • 5'-UTR G-quadruplex structures acting as translational repressors
    • Beaudoin, J. D., & Perreault, J. P. (2010). 5'-UTR G-quadruplex structures acting as translational repressors. Nucleic Acids Research, 38, 7022-7036.
    • (2010) Nucleic Acids Research , vol.38 , pp. 7022-7036
    • Beaudoin, J.D.1    Perreault, J.P.2
  • 76
    • 77957082956 scopus 로고    scopus 로고
    • A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells
    • Gomez, D., Guedin, A., Mergny, J. L., Salles, B., Riou, J. F., Teulade-Fichou, M. P., et al. (2010). A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Research, 38, 7187-7198.
    • (2010) Nucleic Acids Research , vol.38 , pp. 7187-7198
    • Gomez, D.1    Guedin, A.2    Mergny, J.L.3    Salles, B.4    Riou, J.F.5    Teulade-Fichou, M.P.6
  • 77
    • 67049134254 scopus 로고    scopus 로고
    • An unusually stable G-quadruplex within the 5'-UTR of the MT3 matrix metalloproteinase mRNA represses translation in eukaryotic cells
    • Morris, M. J., & Basu, S. (2009). An unusually stable G-quadruplex within the 5'-UTR of the MT3 matrix metalloproteinase mRNA represses translation in eukaryotic cells. Biochemistry, 48, 5313-5319.
    • (2009) Biochemistry , vol.48 , pp. 5313-5319
    • Morris, M.J.1    Basu, S.2
  • 78
    • 77957061503 scopus 로고    scopus 로고
    • The BCL-2 5' untranslated region contains an RNA G-quadruplexforming motif that modulates protein expression
    • Shahid, R., Bugaut, A., & Balasubramanian, S. (2010). The BCL-2 5' untranslated region contains an RNA G-quadruplexforming motif that modulates protein expression. Biochemistry, 49, 8300-8306.
    • (2010) Biochemistry , vol.49 , pp. 8300-8306
    • Shahid, R.1    Bugaut, A.2    Balasubramanian, S.3
  • 80
    • 0035900649 scopus 로고    scopus 로고
    • Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
    • DOI 10.1016/S0092-8674(01)00566-9
    • Darnell, J. C., Jensen, K. B., Jin, P., Brown, V., Warren, S. T., & Darnell, R. B. (2001). Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell, 107, 489-499. (Pubitemid 33152784)
    • (2001) Cell , vol.107 , Issue.4 , pp. 489-499
    • Darnell, J.C.1    Jensen, K.B.2    Jin, P.3    Brown, V.4    Warren, S.T.5    Darnell, R.B.6
  • 82
    • 1242342930 scopus 로고    scopus 로고
    • Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing
    • DOI 10.1093/nar/gkh181
    • Gomez, D., Lemarteleur, T., Lacroix, L., Mailliet, P., Mergny, J. L., & Riou, J. F. (2004). Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. Nucleic Acids Research, 32, 371-379. (Pubitemid 38228637)
    • (2004) Nucleic Acids Research , vol.32 , Issue.1 , pp. 371-379
    • Gomez, D.1    Lamarteleur, T.2    Lacroix, L.3    Mailliet, P.4    Mergny, J.-L.5    Riou, J.-F.6
  • 83
    • 79952299200 scopus 로고    scopus 로고
    • G-quadruplex structures in TP53 intron 3: Role in alternative splicing and in production of p53 mRNA isoforms
    • Marcel, V. et al. (2010). G-quadruplex structures in TP53 intron 3: Role in alternative splicing and in production of p53 mRNA isoforms. Carcinogenesis, 32, 271-278.
    • (2010) Carcinogenesis , vol.32 , pp. 271-278
    • Marcel, V.1
  • 84
    • 37349043972 scopus 로고    scopus 로고
    • Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends
    • DOI 10.1126/science.1147182
    • Azzalin, C. M., Reichenbach, P., Khoriauli, L., Giulotto, E., & Lingner, J. (2007). Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science, 318, 798-801. (Pubitemid 351411771)
    • (2007) Science , vol.318 , Issue.5851 , pp. 798-801
    • Azzalin, C.M.1    Reichenbach, P.2    Khoriauli, L.3    Giulotto, E.4    Lingner, J.5
  • 85
    • 77956539976 scopus 로고    scopus 로고
    • A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
    • Collie, G. W., Haider, S. M., Neidle, S., & Parkinson, G. N. (2010). A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex. Nucleic Acids Research, 38, 5569-5580.
    • (2010) Nucleic Acids Research , vol.38 , pp. 5569-5580
    • Collie, G.W.1    Haider, S.M.2    Neidle, S.3    Parkinson, G.N.4
  • 86
    • 67749143935 scopus 로고    scopus 로고
    • + solution
    • Martadinata, H.,&Phan, A. T. (2009). Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution. Journal of the American Chemical Society, 131, 2570-2579.
    • (2009) Journal of the American Chemical Society , vol.131 , pp. 2570-2579
    • Martadinata, H.1    Phan, A.T.2
  • 87
    • 50249134295 scopus 로고    scopus 로고
    • G-quadruplex formation by human telomeric repeats-containing RNA in Na + solution
    • Xu, Y., Kaminaga, K., & Komiyama, M. (2008). G-quadruplex formation by human telomeric repeats-containing RNA in Na + solution. Journal of the American Chemical Society, 130, 11179-11184.
    • (2008) Journal of the American Chemical Society , vol.130 , pp. 11179-11184
    • Xu, Y.1    Kaminaga, K.2    Komiyama, M.3
  • 88
    • 67651207528 scopus 로고    scopus 로고
    • Differential biophysical behavior of human telomeric RNA and DNA quadruplex
    • Arora, A., & Maiti, S. (2009). Differential biophysical behavior of human telomeric RNA and DNA quadruplex. Journal of Physical Chemistry B, 113, 10515-10520.
    • (2009) Journal of Physical Chemistry B , vol.113 , pp. 10515-10520
    • Arora, A.1    Maiti, S.2
  • 89
    • 69949186768 scopus 로고    scopus 로고
    • A comparison of DNA and RNA quadruplex structures and stabilities
    • Joachimi, A., Benz, A., & Hartig, J. S. (2009). A comparison of DNA and RNA quadruplex structures and stabilities. Bioorganic and Medicinal Chemistry, 17, 6811-6815.
    • (2009) Bioorganic and Medicinal Chemistry , vol.17 , pp. 6811-6815
    • Joachimi, A.1    Benz, A.2    Hartig, J.S.3
  • 91
    • 3042785608 scopus 로고    scopus 로고
    • Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
    • DOI 10.1101/gad.1200804
    • Duquette, M. L., Handa, P., Vincent, J. A., Taylor, A. F., & Maizels, N. (2004). Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes and Development, 18, 1618-1629. (Pubitemid 38868912)
    • (2004) Genes and Development , vol.18 , Issue.13 , pp. 1618-1629
    • Duquette, M.L.1    Handa, P.2    Vincent, J.A.3    Taylor, A.F.4    Maizels, N.5
  • 92
    • 77449156015 scopus 로고    scopus 로고
    • Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments
    • Schaffitzel, C., Postberg, J., Paeschke, K., & Lipps, H. J. (2010). Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments. Methods in Molecular Biology, 608, 159-181.
    • (2010) Methods in Molecular Biology , vol.608 , pp. 159-181
    • Schaffitzel, C.1    Postberg, J.2    Paeschke, K.3    Lipps, H.J.4
  • 93
    • 44849095213 scopus 로고    scopus 로고
    • Telomerase recruitment by the telomere end binding protein- facilitates G-quadruplex DNA unfolding in ciliates
    • DOI 10.1038/nsmb.1422, PII NSMB1422
    • Paeschke, K., Juranek, S., Simonsson, T., Hempel, A., Rhodes, D., &Lipps, H. J. (2008). Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates. Nature Structural and Molecular Biology, 15, 598-604. (Pubitemid 351799132)
    • (2008) Nature Structural and Molecular Biology , vol.15 , Issue.6 , pp. 598-604
    • Paeschke, K.1    Juranek, S.2    Simonsson, T.3    Hempel, A.4    Rhodes, D.5    Lipps, H.J.6
  • 94
    • 27144451010 scopus 로고    scopus 로고
    • Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
    • DOI 10.1038/nsmb982, PII N982
    • Paeschke, K., Simonsson, T., Postberg, J., Rhodes, D., & Lipps, H. J. (2005). Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nature Structural and Molecular Biology, 12, 847-854. (Pubitemid 41486707)
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.10 , pp. 847-854
    • Paeschke, K.1    Simonsson, T.2    Postberg, J.3    Rhodes, D.4    Lipps, H.J.5
  • 95
    • 37049004147 scopus 로고    scopus 로고
    • Targeting telomeres and telomerase
    • DOI 10.1016/j.biochi.2007.07.011, PII S0300908407001873, Telomeres and Telomerase: from Basic Research to Clinical Applications
    • De Cian, A., Lacroix, L., Douarre, C., Temime-Smaali, N., Trentesaux, C., Riou, J. F., et al. (2008). Targeting telomeres and telomerase. Biochimie, 90, 131-155. (Pubitemid 350245369)
    • (2008) Biochimie , vol.90 , Issue.1 , pp. 131-155
    • De Cian, A.1    Lacroix, L.2    Douarre, C.3    Temime-Smaali, N.4    Trentesaux, C.5    Riou, J.-F.6    Mergny, J.-L.7
  • 96
    • 39049147645 scopus 로고    scopus 로고
    • A hitchhiker's guide to G-quadruplex ligands
    • DOI 10.1039/b714772b
    • Monchaud, D., & Teulade-Fichou, M. P. (2008). A hitchhiker's guide to G-quadruplex ligands. Organic and Biomolecular Chemistry, 6, 627-636. (Pubitemid 351972601)
    • (2008) Organic and Biomolecular Chemistry , vol.6 , Issue.4 , pp. 627-636
    • Monchaud, D.1    Teulade-Fichou, M.-P.2
  • 98
    • 0032497405 scopus 로고    scopus 로고
    • NMR-based model of a telomerase-inhibiting compound bound to G- quadruplex DNA
    • DOI 10.1021/bi981330n
    • Fedoroff, O. Y., Salazar, M., Han, H., Chemeris, V. V., Kerwin, S. M., & Hurley, L. H. (1998). NMR-Based model of a telomerase- inhibiting compound bound to G-quadruplex DNA. Biochemistry, 37, 12367-12374. (Pubitemid 28427520)
    • (1998) Biochemistry , vol.37 , Issue.36 , pp. 12367-12374
    • Fedoroff, O.Yu.1    Salazar, M.2    Han, H.3    Chemeris, V.V.4    Kerwin, S.M.5    Hurley, L.H.6
  • 99
    • 0032495774 scopus 로고    scopus 로고
    • Cationic porphyrins as telomerase inhibitors: The interaction of tetra- (N-methyl-4-pyridyl)porphine with quadruplex DNA [1]
    • DOI 10.1021/ja973792e
    • Wheelhouse, R. T., Sun, D. K., Han, H. Y., Han, F. X., & Hurley, L. H. (1998). Cationic porphyrins as telomerase inhibitors: The interaction of tetra-(N-methyl-4-pyridyl)porphine with quadruplex DNA. Journal of the American Chemical Society, 120, 3261-3262. (Pubitemid 28204540)
    • (1998) Journal of the American Chemical Society , vol.120 , Issue.13 , pp. 3261-3262
    • Wheelhouse, R.T.1    Sun, D.2    Han, H.3    Han, F.X.4    Hurley, L.H.5
  • 105
    • 0037070575 scopus 로고    scopus 로고
    • Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G-quadruplex
    • DOI 10.1021/ja017308q
    • Kim, M. Y., Vankayalapati, H., Shin-Ya, K., Wierzba, K., & Hurley, L. H. (2002). Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. Journal of the American Chemical Society, 124, 2098-2099. (Pubitemid 34267081)
    • (2002) Journal of the American Chemical Society , vol.124 , Issue.10 , pp. 2098-2099
    • Kim, M.-Y.1    Vankayalapati, H.2    Shin-Ya, K.3    Wierzba, K.4    Hurley, L.H.5
  • 106
    • 21644460419 scopus 로고    scopus 로고
    • Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure
    • DOI 10.1021/ja0505088
    • Rezler, E. M., Seenisamy, J., Bashyam, S., Kim, M. Y., White, E., Wilson, W. D., et al. (2005). Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure. Journal of the American Chemical Society, 127, 9439-9447. (Pubitemid 40934756)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.26 , pp. 9439-9447
    • Rezler, E.M.1    Seenisamy, J.2    Bashyam, S.3    Kim, M.-Y.4    White, E.5    Wilson, W.D.6    Hurley, L.H.7
  • 108
    • 0037731436 scopus 로고    scopus 로고
    • The different biological effects of Telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures
    • Kim, M. Y., Gleason-Guzman, M., Izbicka, E., Nishioka, D., & Hurley, L. H. (2003). The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures. Cancer Research, 63, 3247-3256. (Pubitemid 36735879)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3247-3256
    • Kim, M.-Y.1    Gleason-Guzman, M.2    Izbicka, E.3    Nishioka, D.4    Hurley, L.H.5
  • 109
    • 0842289983 scopus 로고    scopus 로고
    • Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma
    • DOI 10.1158/1078-0432.CCR-0793-03
    • Shammas, M. A., Shmookler Reis, R. J., Li, C., Koley, H., Hurley, L. H., Anderson, K. C., et al. (2004). Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma. Clinical Cancer Research, 10, 770-776. (Pubitemid 38174015)
    • (2004) Clinical Cancer Research , vol.10 , Issue.2 , pp. 770-776
    • Shammas, M.A.1    Shmookler Reis, R.J.2    Li, C.3    Koley, H.4    Hurley, L.H.5    Anderson, K.C.6    Munshi, N.C.7
  • 110
    • 33645280314 scopus 로고    scopus 로고
    • G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells
    • Tahara, H., Shin-Ya, K., Seimiya, H., Yamada, H., Tsuruo, T., & Ide, T. (2006). G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells. Oncogene, 25, 1955-1966.
    • (2006) Oncogene , vol.25 , pp. 1955-1966
    • Tahara, H.1    Shin-Ya, K.2    Seimiya, H.3    Yamada, H.4    Tsuruo, T.5    Ide, T.6
  • 111
    • 0041353443 scopus 로고    scopus 로고
    • Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: Involvement of ATM-dependent DNA damage response pathways
    • DOI 10.1038/sj.onc.1206833
    • Tauchi, T., Shin-Ya, K., Sashida, G., Sumi, M., Nakajima, A., Shimamoto, T., et al. (2003). Activity of a novel G-quadruplexinteractive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: Involvement of ATM-dependent DNA damage response pathways. Oncogene, 22, 5338-5347. (Pubitemid 37056096)
    • (2003) Oncogene , vol.22 , Issue.34 , pp. 5338-5347
    • Tauchi, T.1    Shin-Ya, K.2    Sashida, G.3    Sumi, M.4    Nakajima, A.5    Shimamoto, T.6    Ohyashiki, J.H.7    Ohyashiki, K.8
  • 112
    • 33748701981 scopus 로고    scopus 로고
    • Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: In vitro and in vivo studies in acute leukemia
    • DOI 10.1038/sj.onc.1209577, PII 1209577
    • Tauchi, T., Shin-ya, K., Sashida, G., Sumi, M., Okabe, S., Ohyashiki, J. H., et al. (2006). Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: In vitro and in vivo studies in acute leukemia. Oncogene, 25, 5719-5725. (Pubitemid 44435249)
    • (2006) Oncogene , vol.25 , Issue.42 , pp. 5719-5725
    • Tauchi, T.1    Shin-Ya, K.2    Sashida, G.3    Sumi, M.4    Okabe, S.5    Ohyashiki, J.H.6    Ohyashiki, K.7
  • 115
    • 13944272246 scopus 로고    scopus 로고
    • The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function
    • DOI 10.1158/0008-5472.CAN-04-2910
    • Burger, A. M., Dai, F., Schultes, C. M., Reszka, A. P., Moore, M. J., Double, J. A., et al. (2005). The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function. Cancer Research, 65, 1489-1496. (Pubitemid 40270178)
    • (2005) Cancer Research , vol.65 , Issue.4 , pp. 1489-1496
    • Burger, A.M.1    Dai, F.2    Schultes, C.M.3    Reszka, A.P.4    Moore, M.J.5    Double, J.A.6    Neidle, S.7
  • 117
    • 34247208639 scopus 로고    scopus 로고
    • Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism
    • DOI 10.1038/sj.bjc.6603691, PII 6603691
    • Phatak, P., Cookson, J. C., Dai, F., Smith, V., Gartenhaus, R. B., Stevens, M. F., et al. (2007). Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism. British Journal of Cancer, 96, 1223-1233. (Pubitemid 46625068)
    • (2007) British Journal of Cancer , vol.96 , Issue.8 , pp. 1223-1233
    • Phatak, P.1    Cookson, J.C.2    Dai, F.3    Smith, V.4    Gartenhaus, R.B.5    Stevens, M.F.G.6    Burger, A.M.7
  • 119
    • 37349056426 scopus 로고    scopus 로고
    • Quadruplex-coupled kinetics distinguishes ligand binding between G4 DNA motifs
    • DOI 10.1021/bi701590z
    • Halder, K., & Chowdhury, S. (2007). Quadruplex-coupled kinetics distinguishes ligand binding between G4 DNA motifs. Biochemistry, 46, 14762-14770. (Pubitemid 350308868)
    • (2007) Biochemistry , vol.46 , Issue.51 , pp. 14762-14770
    • Halder, K.1    Chowdhury, S.2
  • 120
    • 4544261025 scopus 로고    scopus 로고
    • Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase
    • DOI 10.1016/j.bbrc.2004.08.150, PII S0006291X04019369
    • Lemarteleur, T., Gomez, D., Paterski, R., Mandine, E., Mailliet, P., & Riou, J. F. (2004). Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase. Biochemical and Biophysical Research Communications, 323, 802-808. (Pubitemid 39243390)
    • (2004) Biochemical and Biophysical Research Communications , vol.323 , Issue.3 , pp. 802-808
    • Lemarteleur, T.1    Gomez, D.2    Paterski, R.3    Mandine, E.4    Mailliet, P.5    Riou, J.-F.6
  • 121
    • 77449106454 scopus 로고    scopus 로고
    • Preparation of G-quartet structures and detection by native gel electrophoresis
    • Moon, I. K., & Jarstfer, M. B. (2010). Preparation of G-quartet structures and detection by native gel electrophoresis. Methods in Molecular Biology, 608, 51-63.
    • (2010) Methods in Molecular Biology , vol.608 , pp. 51-63
    • Moon, I.K.1    Jarstfer, M.B.2
  • 123
    • 0025896273 scopus 로고
    • Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates
    • Hardin, C. C., Henderson, E., Watson, T., & Prosser, J. K. (1991). Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates. Biochemistry, 30, 4460-4472.
    • (1991) Biochemistry , vol.30 , pp. 4460-4472
    • Hardin, C.C.1    Henderson, E.2    Watson, T.3    Prosser, J.K.4
  • 125
  • 126
    • 77449125296 scopus 로고    scopus 로고
    • Monitoring the temperature unfolding of G-quadruplexes by UV and circular dichroism spectroscopies and calorimetry techniques
    • Olsen, C. M., & Marky, L. A. (2010). Monitoring the temperature unfolding of G-quadruplexes by UV and circular dichroism spectroscopies and calorimetry techniques. Methods in Molecular Biology, 608, 147-158.
    • (2010) Methods in Molecular Biology , vol.608 , pp. 147-158
    • Olsen, C.M.1    Marky, L.A.2
  • 128
    • 77449111348 scopus 로고    scopus 로고
    • Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay
    • Sun, D., & Hurley, L. H. (2010). Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay. Methods in Molecular Biology, 608, 65-79.
    • (2010) Methods in Molecular Biology , vol.608 , pp. 65-79
    • Sun, D.1    Hurley, L.H.2
  • 129
    • 77449091090 scopus 로고    scopus 로고
    • Real-time observation of G-quadruplex dynamics using single-molecule FRET microscopy
    • Okumus, B., & Ha, T. (2010). Real-time observation of G-quadruplex dynamics using single-molecule FRET microscopy. Methods in Molecular Biology, 608, 81-96.
    • (2010) Methods in Molecular Biology , vol.608 , pp. 81-96
    • Okumus, B.1    Ha, T.2
  • 131
    • 0026554887 scopus 로고
    • Quadruplex structure of Oxytricha telomeric DNA oligonucleotides
    • Smith, F. W., & Feigon, J. (1992). Quadruplex structure of Oxytricha telomeric DNA oligonucleotides. Nature, 356, 164-168.
    • (1992) Nature , vol.356 , pp. 164-168
    • Smith, F.W.1    Feigon, J.2
  • 132
    • 0027240171 scopus 로고
    • 4) in solution
    • Smith, F. W., & Feigon, J. (1993). Strand orientation in the DNA quadruplex formed from the Oxytricha telomere repeat oligonucleotide d(G4T4G4) in solution. Biochemistry, 32, 8682-8692. (Pubitemid 23270456)
    • (1993) Biochemistry , vol.32 , Issue.33 , pp. 8682-8692
    • Smith, F.W.1    Feigon, J.2
  • 133
    • 0026687030 scopus 로고
    • Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution
    • Wang, Y., & Patel, D. J. (1992). Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution. Biochemistry, 31, 8112-8119.
    • (1992) Biochemistry , vol.31 , pp. 8112-8119
    • Wang, Y.1    Patel, D.J.2
  • 134
    • 0027918585 scopus 로고
    • Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex
    • DOI 10.1016/0969-2126(93)90015-9
    • Wang, Y., & Patel, D. J. (1993). Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure, 1, 263-282. (Pubitemid 2031126)
    • (1993) Structure , vol.1 , Issue.4 , pp. 263-282
    • Wang Yong1    Patel, D.J.2
  • 135
    • 0028774726 scopus 로고
    • 4 G-tetraplex
    • Wang, Y., & Patel, D. J. (1994). Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex. Structure, 2, 1141-1156. (Pubitemid 124001314)
    • (1994) Structure , vol.2 , Issue.12 , pp. 1141-1156
    • Wang, Y.1    Patel, D.J.2
  • 136
    • 0026591751 scopus 로고
    • Crystal structure of four-stranded Oxytricha telomeric DNA
    • Kang, C., Zhang, X., Ratliff, R., Moyzis, R., & Rich, A. (1992). Crystal structure of four-stranded Oxytricha telomeric DNA. Nature, 356, 126-131.
    • (1992) Nature , vol.356 , pp. 126-131
    • Kang, C.1    Zhang, X.2    Ratliff, R.3    Moyzis, R.4    Rich, A.5
  • 138
    • 84856253934 scopus 로고    scopus 로고
    • Cambridge: Lynne Cox, Royal Society of Chemistry
    • Bryan, T. (Ed.). (2009). Molecular Themes in DNA Replication (p. 264). Cambridge: Lynne Cox, Royal Society of Chemistry.
    • (2009) Molecular Themes in DNA Replication , pp. 264
    • Bryan, T.1


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