Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase

Biochemical and Biophysical Research Communications

Volumn 323, Issue 3, 2004, Pages 802-808

  Lemarteleur, Thibault ^a   Gomez, Dennis ^a   Paterski, Rajaa ^a   Mandine, Eliane ^b   Mailliet, Patrick ^b   Riou, Jean François ^a  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b SANOFI   (France)

Author keywords

c myc; G quadruplex; PCR stop assay; Telomerase inhibitor

Indexed keywords

AMIDE; DICARBOXYLIC ACID; GUANINE; LIGAND; OLIGONUCLEOTIDE; PROTEIN; PYRIDINE; TELOMERASE INHIBITOR; TELOMESTATIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DEGRADATION; ENZYME SPECIFICITY; ENZYME STABILITY; GENE MUTATION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NUCLEOTIDE REPEAT; ONCOGENE C MYC; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; TELOMERE; TRANSCRIPTION INITIATION;

BINDING SITES; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME STABILITY; LIGANDS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; QUINOLINIUM COMPOUNDS; TELOMERASE; TRANSCRIPTION FACTORS; TRIAZINES;

EID: 4544261025     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.150     Document Type: Article

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