-
1
-
-
33751020853
-
Quadruplex DNA: Sequence, topology and structure
-
S. Burge, G.N. Parkinson, P. Hazel, A.K. Todd, and S. Neidle Quadruplex DNA: sequence, topology and structure Nucleic Acids Res. 34 2006 5402 5415
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 5402-5415
-
-
Burge, S.1
Parkinson, G.N.2
Hazel, P.3
Todd, A.K.4
Neidle, S.5
-
2
-
-
76349122184
-
Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer
-
S. Neidle Human telomeric G-quadruplex: the current status of telomeric G-quadruplexes as therapeutic targets in human cancer FEBS J. 277 2010 1118 1125
-
(2010)
FEBS J.
, vol.277
, pp. 1118-1125
-
-
Neidle, S.1
-
3
-
-
76349097100
-
Human telomeric G-quadruplex: Structures of DNA and RNA sequences
-
A.T. Phan Human telomeric G-quadruplex: structures of DNA and RNA sequences FEBS J. 277 2010 1107 1117
-
(2010)
FEBS J.
, vol.277
, pp. 1107-1117
-
-
Phan, A.T.1
-
4
-
-
68549136741
-
G-quadruplex structures: In vivo evidence and function
-
H.J. Lipps, and D. Rhodes G-quadruplex structures: in vivo evidence and function Trends Cell Biol. 19 2009 414 422
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 414-422
-
-
Lipps, H.J.1
Rhodes, D.2
-
5
-
-
78049298053
-
G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae
-
J.A. Capra, K. Paeschke, M. Singh, and V.A. Zakian G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae PLoS Comput. Biol. 6 2010 e1000861
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. 1000861
-
-
Capra, J.A.1
Paeschke, K.2
Singh, M.3
Zakian, V.A.4
-
6
-
-
55249100310
-
Design of selective G-quadruplex ligands as potential anticancer agents
-
J.H. Tan, L.Q. Gu, and J.Y. Wu Design of selective G-quadruplex ligands as potential anticancer agents Mini Rev. Med. Chem. 8 2008 1163 1178
-
(2008)
Mini Rev. Med. Chem.
, vol.8
, pp. 1163-1178
-
-
Tan, J.H.1
Gu, L.Q.2
Wu, J.Y.3
-
7
-
-
0038150335
-
The design of G-quadruplex ligands as telomerase inhibitors
-
J. Cuesta, M.A. Read, and S. Neidle The design of G-quadruplex ligands as telomerase inhibitors Mini Rev. Med. Chem. 3 2003 11 21
-
(2003)
Mini Rev. Med. Chem.
, vol.3
, pp. 11-21
-
-
Cuesta, J.1
Read, M.A.2
Neidle, S.3
-
8
-
-
40749091190
-
The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase
-
M. Franceschin, C.M. Lombardo, E. Pascucci, D. D'Ambrosio, E. Micheli, A. Bianco, G. Ortaggi, and M. Savino The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase Bioorg. Med. Chem. 16 2008 2292 2304
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 2292-2304
-
-
Franceschin, M.1
Lombardo, C.M.2
Pascucci, E.3
D'Ambrosio, D.4
Micheli, E.5
Bianco, A.6
Ortaggi, G.7
Savino, M.8
-
9
-
-
67649647842
-
Selective G-quadruplex ligands: The significant role of side chain charge density in a series of perylene derivatives
-
E. Micheli, C.M. Lombardo, D. D'Ambrosio, M. Franceschin, S. Neidle, and M. Savino Selective G-quadruplex ligands: the significant role of side chain charge density in a series of perylene derivatives Bioorg. Med. Chem. Lett. 19 2009 3903 3908
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 3903-3908
-
-
Micheli, E.1
Lombardo, C.M.2
D'Ambrosio, D.3
Franceschin, M.4
Neidle, S.5
Savino, M.6
-
10
-
-
77949884776
-
Water soluble cationic perylene derivatives as possible telomerase inhibitors: The search for selective G-quadruplex targeting
-
E. Micheli, D. D'Ambrosio, M. Franceschin, and M. Savino Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting Mini Rev. Med. Chem. 9 2009 1622 1632
-
(2009)
Mini Rev. Med. Chem.
, vol.9
, pp. 1622-1632
-
-
Micheli, E.1
D'Ambrosio, D.2
Franceschin, M.3
Savino, M.4
-
11
-
-
20144364292
-
Prevalence of quadruplexes in the human genome
-
J.L. Huppert, and S. Balasubramanian Prevalence of quadruplexes in the human genome Nucleic Acids Res. 33 2005 2908 2916
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 2908-2916
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
12
-
-
47849105417
-
Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions
-
Y. Qin, and L.H. Hurley Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions Biochimie 90 2008 1149 1171
-
(2008)
Biochimie
, vol.90
, pp. 1149-1171
-
-
Qin, Y.1
Hurley, L.H.2
-
13
-
-
0037015078
-
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
-
A. Siddiqui-Jain, C.L. Grand, D.J. Bearss, and L.H. Hurley Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription Proc. Natl Acad. Sci. USA 99 2002 11593 11598
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 11593-11598
-
-
Siddiqui-Jain, A.1
Grand, C.L.2
Bearss, D.J.3
Hurley, L.H.4
-
15
-
-
68249156463
-
Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands
-
S.L. Palumbo, S.W. Ebbinghaus, and L.H. Hurley Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands J. Am. Chem. Soc. 131 2009 10878 10891
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 10878-10891
-
-
Palumbo, S.L.1
Ebbinghaus, S.W.2
Hurley, L.H.3
-
16
-
-
77956252000
-
Coexistence of two distinct G-quadruplex conformations in the hTERT promoter
-
K.W. Lim, L. Lacroix, D.J. Yue, J.K. Lim, J.M. Lim, and A.T. Phan Coexistence of two distinct G-quadruplex conformations in the hTERT promoter J. Am. Chem. Soc. 132 2010 12331 12342
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 12331-12342
-
-
Lim, K.W.1
Lacroix, L.2
Yue, D.J.3
Lim, J.K.4
Lim, J.M.5
Phan, A.T.6
-
17
-
-
73149092074
-
Telomeres and telomerase: From discovery to clinical trials
-
D.R. Corey Telomeres and telomerase: from discovery to clinical trials Chem. Biol. 16 2009 1219 1223
-
(2009)
Chem. Biol.
, vol.16
, pp. 1219-1223
-
-
Corey, D.R.1
-
18
-
-
14344265993
-
Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells
-
M. Folini, C. Brambilla, R. Villa, P. Gandellini, S. Vignati, F. Paduano, M.G. Daidone, and N. Zaffaroni Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells Eur. J. Cancer 41 2005 624 634
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 624-634
-
-
Folini, M.1
Brambilla, C.2
Villa, R.3
Gandellini, P.4
Vignati, S.5
Paduano, F.6
Daidone, M.G.7
Zaffaroni, N.8
-
19
-
-
0029872174
-
Telomerase activity in human germline and embryonic tissues and cells
-
W.E. Wright, M.A. Piatyszek, W.E. Rainey, W. Byrd, and J.W. Shay Telomerase activity in human germline and embryonic tissues and cells Dev. Genet. 18 1996 173 179
-
(1996)
Dev. Genet.
, vol.18
, pp. 173-179
-
-
Wright, W.E.1
Piatyszek, M.A.2
Rainey, W.E.3
Byrd, W.4
Shay, J.W.5
-
20
-
-
34347214448
-
A model for triple helix formation on human telomerase reverse transcriptase (hTERT) promoter and stabilization by specific interactions with the water soluble perylene derivative, DAPER
-
L. Rossetti, G. D'Isa, C. Mauriello, M. Varra, P. De Santis, L. Mayol, and M. Savino A model for triple helix formation on human telomerase reverse transcriptase (hTERT) promoter and stabilization by specific interactions with the water soluble perylene derivative, DAPER Biophys. Chem. 129 2007 70 81
-
(2007)
Biophys. Chem.
, vol.129
, pp. 70-81
-
-
Rossetti, L.1
D'Isa, G.2
Mauriello, C.3
Varra, M.4
De Santis, P.5
Mayol, L.6
Savino, M.7
-
21
-
-
46149122709
-
Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter
-
S. Pisano, M. Varra, E. Micheli, T. Coppola, P. De Santis, L. Mayol, and M. Savino Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter Biophys. Chem. 136 2008 159 163
-
(2008)
Biophys. Chem.
, vol.136
, pp. 159-163
-
-
Pisano, S.1
Varra, M.2
Micheli, E.3
Coppola, T.4
De Santis, P.5
Mayol, L.6
Savino, M.7
-
22
-
-
1042267433
-
Dual role of sequence-dependent DNA curvature in nucleosome stability: The critical test of highly bent Crithidia fasciculata DNA tract
-
A. Scipioni, S. Pisano, C. Anselmi, M. Savino, and P. De Santis Dual role of sequence-dependent DNA curvature in nucleosome stability: the critical test of highly bent Crithidia fasciculata DNA tract Biophys. Chem. 107 2004 7 17
-
(2004)
Biophys. Chem.
, vol.107
, pp. 7-17
-
-
Scipioni, A.1
Pisano, S.2
Anselmi, C.3
Savino, M.4
De Santis, P.5
-
23
-
-
0037160543
-
From the sequence to the superstructural properties of DNAs
-
C. Anselmi, P. De Santis, R. Paparcone, M. Savino, and A. Scipioni From the sequence to the superstructural properties of DNAs Biophys. Chem. 95 2002 23 47
-
(2002)
Biophys. Chem.
, vol.95
, pp. 23-47
-
-
Anselmi, C.1
De Santis, P.2
Paparcone, R.3
Savino, M.4
Scipioni, A.5
-
25
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
K. Luger, A.W. Mader, R.K. Richmond, D.F. Sargent, and T.J. Richmond Crystal structure of the nucleosome core particle at 2.8 A resolution Nature 389 1997 251 260
-
(1997)
Nature
, vol.389
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
26
-
-
77953314889
-
Prediction of nucleosome positioning in genomes: Limits and perspectives of physical and bioinformatic approaches
-
P. De Santis, S. Morosetti, and A. Scipioni Prediction of nucleosome positioning in genomes: limits and perspectives of physical and bioinformatic approaches J. Biomol. Struct. Dyn. 27 2010 747 764
-
(2010)
J. Biomol. Struct. Dyn.
, vol.27
, pp. 747-764
-
-
De Santis, P.1
Morosetti, S.2
Scipioni, A.3
-
27
-
-
11244349707
-
The hTERT gene is embedded in a nuclease-resistant chromatin domain
-
S. Wang, and J. Zhu The hTERT gene is embedded in a nuclease-resistant chromatin domain J. Biol. Chem. 279 2004 55401 55410
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 55401-55410
-
-
Wang, S.1
Zhu, J.2
-
28
-
-
72949086633
-
Stable G-quadruplexes are found outside nucleosome-bound regions
-
H.M. Wong, and J.L. Huppert Stable G-quadruplexes are found outside nucleosome-bound regions Mol. Biosyst. 5 2009 1713 1719
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 1713-1719
-
-
Wong, H.M.1
Huppert, J.L.2
-
29
-
-
72449126172
-
Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes
-
L. Martino, B. Pagano, I. Fotticchia, S. Neidle, and C. Giancola Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes J. Phys. Chem. B 113 2009 14779 14786
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 14779-14786
-
-
Martino, L.1
Pagano, B.2
Fotticchia, I.3
Neidle, S.4
Giancola, C.5
-
30
-
-
78649735242
-
Evaluation of human telomeric G-quadruplexes: The influence of overhanging sequences on quadruplex stability and folding
-
V. Viglasky, L. Bauer, K. Tluckova, and P. Javorsky Evaluation of human telomeric G-quadruplexes: the influence of overhanging sequences on quadruplex stability and folding J. Nucleic Acids 2010 2010
-
(2010)
J. Nucleic Acids
, vol.2010
-
-
Viglasky, V.1
Bauer, L.2
Tluckova, K.3
Javorsky, P.4
-
31
-
-
0037119783
-
Perylene diimides with different side chains are selective in inducing different G-quadruplex DNA structures and in inhibiting telomerase
-
L. Rossetti, M. Franceschin, A. Bianco, G. Ortaggi, and M. Savino Perylene diimides with different side chains are selective in inducing different G-quadruplex DNA structures and in inhibiting telomerase Bioorg. Med. Chem. Lett. 12 2002 2527 2533
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2527-2533
-
-
Rossetti, L.1
Franceschin, M.2
Bianco, A.3
Ortaggi, G.4
Savino, M.5
-
32
-
-
0039129145
-
Accelerated assembly of G-quadruplex structures by a small molecule
-
H. Han, C.L. Cliff, and L.H. Hurley Accelerated assembly of G-quadruplex structures by a small molecule Biochemistry 38 1999 6981 6986
-
(1999)
Biochemistry
, vol.38
, pp. 6981-6986
-
-
Han, H.1
Cliff, C.L.2
Hurley, L.H.3
-
34
-
-
77953192496
-
A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures
-
S. Masiero, R. Trotta, S. Pieraccini, S. De Tito, R. Perone, A. Randazzo, and G.P. Spada A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures Org. Biomol. Chem. 8 2010 2683 2692
-
(2010)
Org. Biomol. Chem.
, vol.8
, pp. 2683-2692
-
-
Masiero, S.1
Trotta, R.2
Pieraccini, S.3
De Tito, S.4
Perone, R.5
Randazzo, A.6
Spada, G.P.7
-
35
-
-
0038476179
-
Biophysical and biological properties of quadruplex oligodeoxyribonucleotides
-
V. Dapic, V. Abdomerovic, R. Marrington, J. Peberdy, A. Rodger, J.O. Trent, and P.J. Bates Biophysical and biological properties of quadruplex oligodeoxyribonucleotides Nucleic Acids Res. 31 2003 2097 2107
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2097-2107
-
-
Dapic, V.1
Abdomerovic, V.2
Marrington, R.3
Peberdy, J.4
Rodger, A.5
Trent, J.O.6
Bates, P.J.7
-
36
-
-
0033556134
-
A DNA polymerase stop assay for G-quadruplex-interactive compounds
-
H. Han, L.H. Hurley, and M. Salazar A DNA polymerase stop assay for G-quadruplex-interactive compounds Nucleic Acids Res. 27 1999 537 542
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 537-542
-
-
Han, H.1
Hurley, L.H.2
Salazar, M.3
-
37
-
-
33947098453
-
Histone replacement marks the boundaries of cis-regulatory domains
-
Y. Mito, J.G. Henikoff, and S. Henikoff Histone replacement marks the boundaries of cis-regulatory domains Science 315 2007 1408 1411
-
(2007)
Science
, vol.315
, pp. 1408-1411
-
-
Mito, Y.1
Henikoff, J.G.2
Henikoff, S.3
-
38
-
-
72949109535
-
Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals
-
K. Halder, R. Halder, and S. Chowdhury Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals Mol. Biosyst. 5 2009 1703 1712
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 1703-1712
-
-
Halder, K.1
Halder, R.2
Chowdhury, S.3
-
39
-
-
48749113418
-
G-quadruplex DNA assemblies: Loop length, cation identity, and multimer formation
-
N. Smargiasso, F. Rosu, W. Hsia, P. Colson, E.S. Baker, M.T. Bowers, E. De Pauw, and V. Gabelica G-quadruplex DNA assemblies: loop length, cation identity, and multimer formation J. Am. Chem. Soc. 130 2008 10208 10216
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 10208-10216
-
-
Smargiasso, N.1
Rosu, F.2
Hsia, W.3
Colson, P.4
Baker, E.S.5
Bowers, M.T.6
De Pauw, E.7
Gabelica, V.8
-
40
-
-
33744472232
-
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription
-
S. Cogoi, and L.E. Xodo G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription Nucleic Acids Res. 34 2006 2536 2549
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 2536-2549
-
-
Cogoi, S.1
Xodo, L.E.2
-
41
-
-
38049017592
-
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4
-
Y. Qin, E.M. Rezler, V. Gokhale, D. Sun, and L.H. Hurley Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 Nucleic Acids Res. 35 2007 7698 7713
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7698-7713
-
-
Qin, Y.1
Rezler, E.M.2
Gokhale, V.3
Sun, D.4
Hurley, L.H.5
|