Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 31, 2005, Pages 10864-10869

  Zaug, Arthur J ^a   Podell, Elaine R ^a   Cech, Thomas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

DNA protein complex; G quartet; OB fold; Replication; Telomere

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CELL PROTEIN; PROTEIN POT1; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA STRUCTURE; ENZYME ANALYSIS; EQUILIBRIUM CONSTANT; GENE DISRUPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; STOICHIOMETRY; STRUCTURE ANALYSIS; TELOMERE; YEAST;

BASE SEQUENCE; DNA; DNA PRIMERS; DNA-BINDING PROTEINS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; NUCLEIC ACID CONFORMATION; RECOMBINANT PROTEINS; TELOMERASE; TELOMERE; TELOMERE-BINDING PROTEINS;

EUKARYOTA; SCHIZOSACCHAROMYCES POMBE;

EID: 23344451160     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504744102     Document Type: Article

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