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Volumn , Issue , 2010, Pages 61-70

Androgen receptor biology in prostate cancer

Author keywords

Androgen; Androgen receptor; Beta catenin; Coactivator; Mutation; p160; Prostate cancer

Indexed keywords


EID: 84855835884     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-60327-829-4_5     Document Type: Chapter
Times cited : (2)

References (134)
  • 1
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310(5748):644-648.
    • (2005) Science , vol.310 , Issue.5748 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 2
    • 39049150843 scopus 로고    scopus 로고
    • Role of the TMPRSS2-ERG gene fusion in prostate cancer
    • Tomlins SA, Laxman B, Varambally S et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008; 10(2):177-188.
    • (2008) Neoplasia , vol.10 , Issue.2 , pp. 177-188
    • Tomlins, S.A.1    Laxman, B.2    Varambally, S.3
  • 3
    • 0001189211 scopus 로고
    • Studies on prostatic cancer II. The effect of castration on clinical patients with carcinoma of the prostate
    • Huggins C, Stevens RE, Hodges CL. Studies on prostatic cancer II. The effect of castration on clinical patients with carcinoma of the prostate. Arch Surg 1941; 43:209.
    • (1941) Arch Surg , vol.43 , pp. 209
    • Huggins, C.1    Stevens, R.E.2    Hodges, C.L.3
  • 4
    • 84928580276 scopus 로고
    • Studies on prostatic cancer; Effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C, Hodges C V. Studies on prostatic cancer; effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1941; 1:293-297.
    • (1941) Cancer Res , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 5
    • 0025819482 scopus 로고
    • Immunohistochemical study of androgen receptors in metastatic prostate cancer. Comparison of receptor content and response to hormonal therapy
    • Sadi MV, Walsh PC, Barrack ER. Immunohistochemical study of androgen receptors in metastatic prostate cancer. Comparison of receptor content and response to hormonal therapy. Cancer 1991; 67:3057-3064.
    • (1991) Cancer , vol.67 , pp. 3057-3064
    • Sadi, M.V.1    Walsh, P.C.2    Barrack, E.R.3
  • 6
    • 0020048598 scopus 로고
    • Correlation of prostatic nuclear androgen receptor content with duration of response and survival following hormonal therapy in advanced prostatic cancer
    • Trachtenberg J, Walsh PC. Correlation of prostatic nuclear androgen receptor content with duration of response and survival following hormonal therapy in advanced prostatic cancer. J Urol 1982; 127(3):466-471.
    • (1982) J Urol , vol.127 , Issue.3 , pp. 466-471
    • Trachtenberg, J.1    Walsh, P.C.2
  • 7
    • 0021251553 scopus 로고
    • Relationship between concentrations of extractable and matrix-bound nuclear androgen receptor and clinical response to endocrine therapy for prostatic adenocarcinoma
    • Gonor SE, Lakey WH, McBlain WA. Relationship between concentrations of extractable and matrix-bound nuclear androgen receptor and clinical response to endocrine therapy for prostatic adenocarcinoma. J Urol 1984; 131(6):1196-1201.
    • (1984) J Urol , vol.131 , Issue.6 , pp. 1196-1201
    • Gonor, S.E.1    Lakey, W.H.2    McBlain, W.A.3
  • 8
    • 0023219065 scopus 로고
    • Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy
    • Benson RC, Jr., Gorman PA, O'Brien PC, Holicky EL, Veneziale CM. Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy. Cancer 1987; 59(9): 1599-1606.
    • (1987) Cancer , vol.59 , Issue.9 , pp. 1599-1606
    • Benson Jr., R.C.1    Gorman, P.A.2    O'Brien, P.C.3    Holicky, E.L.4    Veneziale, C.M.5
  • 9
    • 0024274789 scopus 로고
    • Relationship of androgen receptors to the growth and regression of the prostate
    • Rennie PS, Bruchovsky N, Goldenberg SL. Relationship of androgen receptors to the growth and regression of the prostate. Am J Clin Oncol 1988; 11:S13.
    • (1988) Am J Clin Oncol , vol.11
    • Rennie, P.S.1    Bruchovsky, N.2    Goldenberg, S.L.3
  • 10
    • 0020052983 scopus 로고
    • Predicting response of prostatic carcinoma to endocrine therapy
    • Castellanos JM, Galan A, Calvo MA, Schwartz S. Predicting response of prostatic carcinoma to endocrine therapy. Lancet 1982; 1(8269):448.
    • (1982) Lancet , vol.1 , Issue.8269 , pp. 448
    • Castellanos, J.M.1    Galan, A.2    Calvo, M.A.3    Schwartz, S.4
  • 11
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen CD, Welsbie DS, Tran C et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004; 10(1):33-39.
    • (2004) Nat Med , vol.10 , Issue.1 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 12
    • 77956684050 scopus 로고    scopus 로고
    • Regulation of andro-gen action
    • Roy AK, Lavrovsky Y, Song CS et al. Regulation of andro-gen action. Vitam Horm 1999; 55:309-352.
    • (1999) Vitam Horm , vol.55 , pp. 309-352
    • Roy, A.K.1    Lavrovsky, Y.2    Song, C.S.3
  • 13
    • 0030347316 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Gelmann EP. Androgen receptor mutations in prostate cancer. Cancer Treat Res 1996; 87:285-302.
    • (1996) Cancer Treat Res , vol.87 , pp. 285-302
    • Gelmann, E.P.1
  • 18
    • 0033857624 scopus 로고    scopus 로고
    • Androgen-receptor-interacting nuclear proteins
    • Janne OA, Moilanen AM, Poukka H et al. Androgen-receptor-interacting nuclear proteins. Biochem Soc Trans 2000; 28(4):401-405.
    • (2000) Biochem Soc Trans , vol.28 , Issue.4 , pp. 401-405
    • Janne, O.A.1    Moilanen, A.M.2    Poukka, H.3
  • 19
    • 0034880266 scopus 로고    scopus 로고
    • Clinical review 134: The endocrinology of prostate cancer
    • Taplin ME, Ho SM. Clinical review 134: the endocrinology of prostate cancer. J Clin Endocrinol Metab 2001; 86(8): 3467-3477.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.8 , pp. 3467-3477
    • Taplin, M.E.1    Ho, S.M.2
  • 20
    • 0029802619 scopus 로고    scopus 로고
    • Androgen receptors in prostate cancer
    • Bentel JM, Tilley WD. Androgen receptors in prostate cancer. J Endocrinol 1996; 151(1):1-11.
    • (1996) J Endocrinol , vol.151 , Issue.1 , pp. 1-11
    • Bentel, J.M.1    Tilley, W.D.2
  • 21
    • 0023910355 scopus 로고
    • Cloning of human androgen receptor complementary DNA and localization to the X chromosome
    • Lubahn DB, Joseph DR, Sullivan PM, Willard HF, French FS, Wilson EM. Cloning of human androgen receptor complementary DNA and localization to the X chromosome. Science 1988; 240(4850):327-330.
    • (1988) Science , vol.240 , Issue.4850 , pp. 327-330
    • Lubahn, D.B.1    Joseph, D.R.2    Sullivan, P.M.3    Willard, H.F.4    French, F.S.5    Wilson, E.M.6
  • 22
    • 0024555077 scopus 로고
    • Androgen receptor locus on the human X chromosome: Regional localization to Xq11-12 and description of a DNA polymorphism
    • Brown CJ, Goss SJ, Lubahn DB et al. Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism. Am J Hum Genet 1989; 44(2):264-269.
    • (1989) Am J Hum Genet , vol.44 , Issue.2 , pp. 264-269
    • Brown, C.J.1    Goss, S.J.2    Lubahn, D.B.3
  • 23
    • 0034457325 scopus 로고    scopus 로고
    • Complete androgen insensitivity syndrome: Long-term medical, surgical, and psychosexual outcome
    • Wisniewski AB, Migeon CJ, Meyer-Bahlburg HF et al. Complete androgen insensitivity syndrome: long-term medical, surgical, and psychosexual outcome. J Clin Endocrinol Metab 2000; 85(8):2664-2669.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.8 , pp. 2664-2669
    • Wisniewski, A.B.1    Migeon, C.J.2    Meyer-Bahlburg, H.F.3
  • 24
    • 0024306555 scopus 로고
    • Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identifcation of a point mutation in a family with complete androgen insensitivity
    • Lubahn DB, Brown TR, Simental JA et al. Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identifcation of a point mutation in a family with complete androgen insensitivity. Proc Natl Acad Sci USA 1989; 86(23):9534-9538.
    • (1989) Proc Natl Acad Sci USA , vol.86 , Issue.23 , pp. 9534-9538
    • Lubahn, D.B.1    Brown, T.R.2    Simental, J.A.3
  • 25
    • 0024600723 scopus 로고
    • Structural organization of the human androgen receptor gene
    • Kuiper GG, Faber PW, van Rooij HC et al. Structural organization of the human androgen receptor gene. J Mol Endocrinol 1989; 2(3):R1-R4.
    • (1989) J Mol Endocrinol , vol.2 , Issue.3
    • Kuiper, G.G.1    Faber, P.W.2    Van Rooij, H.C.3
  • 26
    • 0027238681 scopus 로고
    • Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1
    • Faber PW, van Rooij HC, Schipper HJ, Brinkmann AO, Trapman J. Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1. J Biol Chem 1993; 268(13):9296-9301.
    • (1993) J Biol Chem , vol.268 , Issue.13 , pp. 9296-9301
    • Faber, P.W.1    Van Rooij, H.C.2    Schipper, H.J.3    Brinkmann, A.O.4    Trapman, J.5
  • 27
    • 1842318283 scopus 로고
    • Characterization and expression of a cDNA encoding the human androgen receptor
    • Tilley WD, Marcelli M, Wilson JD, McPhaul MJ. Characterization and expression of a cDNA encoding the human androgen receptor. Proc Natl Acad Sci USA 1989; 86:327-331.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 327-331
    • Tilley, W.D.1    Marcelli, M.2    Wilson, J.D.3    McPhaul, M.J.4
  • 28
    • 0026399701 scopus 로고
    • The androgen receptor gene is located on a highly conserved region of the X chromosomes of marsupial and monotreme as well as eutherian mammals
    • Spencer JA, Watson JM, Lubahn DB et al. The androgen receptor gene is located on a highly conserved region of the X chromosomes of marsupial and monotreme as well as eutherian mammals. J Hered 1991; 82(2):134-139.
    • (1991) J Hered , vol.82 , Issue.2 , pp. 134-139
    • Spencer, J.A.1    Watson, J.M.2    Lubahn, D.B.3
  • 29
    • 0031662137 scopus 로고    scopus 로고
    • Evolution of the primate androgen receptor: A structural basis for disease
    • Choong CS, Kemppainen JA, Wilson EM. Evolution of the primate androgen receptor: a structural basis for disease. J Mol Evol 1998; 47(3):334-342.
    • (1998) J Mol Evol , vol.47 , Issue.3 , pp. 334-342
    • Choong, C.S.1    Kemppainen, J.A.2    Wilson, E.M.3
  • 30
    • 0034714276 scopus 로고    scopus 로고
    • Structural evidence for ligand specifcity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations
    • Matias PM, Donner P, Coelho R et al. Structural evidence for ligand specifcity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J Biol Chem 2000; 275(34):26164-26171.
    • (2000) J Biol Chem , vol.275 , Issue.34 , pp. 26164-26171
    • Matias, P.M.1    Donner, P.2    Coelho, R.3
  • 31
    • 0035942197 scopus 로고    scopus 로고
    • Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
    • Sack JS, Kish KF, Wang C et al. Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone. Proc Natl Acad Sci USA 2001; 98(9): 4904-4909.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.9 , pp. 4904-4909
    • Sack, J.S.1    Kish, K.F.2    Wang, C.3
  • 32
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau AK, Barstad D, Loria PM et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998; 95(7):927-937.
    • (1998) Cell , vol.95 , Issue.7 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3
  • 33
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski AM, Pike AC, Dauter Z et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997; 389(6652):753-758.
    • (1997) Nature , vol.389 , Issue.6652 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3
  • 34
    • 0032568527 scopus 로고    scopus 로고
    • Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains
    • Tanenbaum DM, Wang Y, Williams SP, Sigler PB. Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci USA 1998; 95(11):5998-6003.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.11 , pp. 5998-6003
    • Tanenbaum, D.M.1    Wang, Y.2    Williams, S.P.3    Sigler, P.B.4
  • 35
    • 0032505096 scopus 로고    scopus 로고
    • Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
    • Nolte RT, Wisely GB, Westin S et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature 1998; 395(6698):137-143.
    • (1998) Nature , vol.395 , Issue.6698 , pp. 137-143
    • Nolte, R.T.1    Wisely, G.B.2    Westin, S.3
  • 36
    • 0027161982 scopus 로고
    • Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains
    • Wong CI, Zhou ZX, Sar M, Wilson EM. Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains. J Biol Chem 1993; 268(25):19004-19012.
    • (1993) J Biol Chem , vol.268 , Issue.25 , pp. 19004-19012
    • Wong, C.I.1    Zhou, Z.X.2    Sar, M.3    Wilson, E.M.4
  • 37
    • 0029560494 scopus 로고
    • Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer
    • Langley E, Zhou ZX, Wilson EM. Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer. J Biol Chem 1995; 270(50):29983-29990.
    • (1995) J Biol Chem , vol.270 , Issue.50 , pp. 29983-29990
    • Langley, E.1    Zhou, Z.X.2    Wilson, E.M.3
  • 38
    • 0033609474 scopus 로고    scopus 로고
    • Redox-dependent DNA binding of the purifed androgen receptor: Evidence for disulfde-linked androgen receptor dimers
    • Liao M, Zhou Z, Wilson EM. Redox-dependent DNA binding of the purifed androgen receptor: evidence for disulfde-linked androgen receptor dimers. Biochemistry 1999; 38(30):9718-9727.
    • (1999) Biochemistry , vol.38 , Issue.30 , pp. 9718-9727
    • Liao, M.1    Zhou, Z.2    Wilson, E.M.3
  • 39
    • 0025957233 scopus 로고
    • Transcriptional activation and nuclear targeting signals of the human androgen receptor
    • Simental JA, Sar M, Lane MV, French FS, Wilson EM. Transcriptional activation and nuclear targeting signals of the human androgen receptor. J Biol Chem 1991; 266(1):510-518.
    • (1991) J Biol Chem , vol.266 , Issue.1 , pp. 510-518
    • Simental, J.A.1    Sar, M.2    Lane, M.V.3    French, F.S.4    Wilson, E.M.5
  • 40
    • 0025800526 scopus 로고
    • Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
    • La Spada AR, Wilson EM, Lubahn DB, Harding AE, Fischbeck KH. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 1991; 352(6330):77-79.
    • (1991) Nature , vol.352 , Issue.6330 , pp. 77-79
    • La Spada, A.R.1    Wilson, E.M.2    Lubahn, D.B.3    Harding, A.E.4    Fischbeck, K.H.5
  • 41
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev 2004; 25(2):276-308.
    • (2004) Endocr Rev , vol.25 , Issue.2 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 42
    • 0033575213 scopus 로고    scopus 로고
    • The linkage of Kennedy's neuron disease to ARA24, the frst identifed androgen receptor polyglutamine region-associated coacti-vator
    • Hsiao PW, Lin DL, Nakao R, Chang C. The linkage of Kennedy's neuron disease to ARA24, the frst identifed androgen receptor polyglutamine region-associated coacti-vator. J Biol Chem 1999; 274(29):20229-20234.
    • (1999) J Biol Chem , vol.274 , Issue.29 , pp. 20229-20234
    • Hsiao, P.W.1    Lin, D.L.2    Nakao, R.3    Chang, C.4
  • 43
    • 0033978514 scopus 로고    scopus 로고
    • Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length
    • Irvine RA, Ma H, Yu MC, Ross RK, Stallcup MR, Coetzee GA. Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length. Hum Mol Genet 2000; 9(2):267-274.
    • (2000) Hum Mol Genet , vol.9 , Issue.2 , pp. 267-274
    • Irvine, R.A.1    Ma, H.2    Yu, M.C.3    Ross, R.K.4    Stallcup, M.R.5    Coetzee, G.A.6
  • 44
    • 0032918844 scopus 로고    scopus 로고
    • Androgen receptor gene CAG repeat length varies in a race-specifc fashion in men without prostate cancer
    • Sartor O, Zheng Q, Eastham JA. Androgen receptor gene CAG repeat length varies in a race-specifc fashion in men without prostate cancer. Urology 1999; 53(2):378-380.
    • (1999) Urology , vol.53 , Issue.2 , pp. 378-380
    • Sartor, O.1    Zheng, Q.2    Eastham, J.A.3
  • 45
    • 33750075191 scopus 로고    scopus 로고
    • Androgen receptor and vitamin D receptor gene polymorphisms and prostate cancer risk
    • Andersson P, Varenhorst E, Soderkvist P. Androgen receptor and vitamin D receptor gene polymorphisms and prostate cancer risk. Eur J Cancer 2006; 42(16):2833-2837.
    • (2006) Eur J Cancer , vol.42 , Issue.16 , pp. 2833-2837
    • Andersson, P.1    Varenhorst, E.2    Soderkvist, P.3
  • 46
    • 37849017532 scopus 로고    scopus 로고
    • Polymorphic CAG and GGC repeat lengths in the androgen receptor gene and prostate cancer risk: Analysis of a Brazilian population
    • Silva NB, Koff WJ, Biolchi V et al. Polymorphic CAG and GGC repeat lengths in the androgen receptor gene and prostate cancer risk: analysis of a Brazilian population. Cancer Invest 2008; 26(1):74-80.
    • (2008) Cancer Invest , vol.26 , Issue.1 , pp. 74-80
    • Silva, N.B.1    Koff, W.J.2    Biolchi, V.3
  • 47
    • 40449086461 scopus 로고    scopus 로고
    • Role of an androgen receptor gene polymorphism in development of hormone refractory prostate cancer in Indian population
    • Mittal RD, Mishra D, Mandhani AK. Role of an androgen receptor gene polymorphism in development of hormone refractory prostate cancer in Indian population. Asian Pac J Cancer Prev 2007; 8(2):275-278.
    • (2007) Asian Pac J Cancer Prev , vol.8 , Issue.2 , pp. 275-278
    • Mittal, R.D.1    Mishra, D.2    Mandhani, A.K.3
  • 48
    • 34249000980 scopus 로고    scopus 로고
    • Association between polymorphisms of the androgen and vitamin D receptor genes with prostate cancer risk in a Mexican population
    • Patino-Garcia B, Arroyo C, Rangel-Villalobos H et al. Association between polymorphisms of the androgen and vitamin D receptor genes with prostate cancer risk in a Mexican population. Rev Invest Clin 2007; 59(1):25-31.
    • (2007) Rev Invest Clin , vol.59 , Issue.1 , pp. 25-31
    • Patino-Garcia, B.1    Arroyo, C.2    Rangel-Villalobos, H.3
  • 49
    • 33645232165 scopus 로고    scopus 로고
    • South Indian men with reduced CAG repeat length in the androgen receptor gene have an increased risk of prostate cancer
    • Krishnaswamy V, Kumarasamy T, Venkatesan V, Shroff S, Jayanth VR, Paul SF. South Indian men with reduced CAG repeat length in the androgen receptor gene have an increased risk of prostate cancer. J Hum Genet 2006; 51(3): 254-257.
    • (2006) J Hum Genet , vol.51 , Issue.3 , pp. 254-257
    • Krishnaswamy, V.1    Kumarasamy, T.2    Venkatesan, V.3    Shroff, S.4    Jayanth, V.R.5    Paul, S.F.6
  • 50
    • 38049041605 scopus 로고    scopus 로고
    • Polymorphisms in genes regulating androgen activity among prostate cancer low-risk Inuit men and high-risk Scandinavians
    • Giwercman C, Giwercman A, Pedersen HS et al. Polymorphisms in genes regulating androgen activity among prostate cancer low-risk Inuit men and high-risk Scandinavians. Int J Androl 2008; 31(1):25-30.
    • (2008) Int J Androl , vol.31 , Issue.1 , pp. 25-30
    • Giwercman, C.1    Giwercman, A.2    Pedersen, H.S.3
  • 51
    • 4444288439 scopus 로고    scopus 로고
    • Structural and functional consequences of glutamine tract variation in the androgen receptor
    • Buchanan G, Yang M, Cheong A et al. Structural and functional consequences of glutamine tract variation in the androgen receptor. Hum Mol Genet 2004; 13(16): 1677-1692.
    • (2004) Hum Mol Genet , vol.13 , Issue.16 , pp. 1677-1692
    • Buchanan, G.1    Yang, M.2    Cheong, A.3
  • 52
    • 38749134831 scopus 로고    scopus 로고
    • Androgen receptor variants and prostate cancer in humanized AR mice
    • Robins DM, Albertelli MA, O'Mahony OA. Androgen receptor variants and prostate cancer in humanized AR mice. J Steroid Biochem Mol Biol 2008; 108(3-5): 230-236.
    • (2008) J Steroid Biochem Mol Biol , vol.108 , Issue.3-5 , pp. 230-236
    • Robins, D.M.1    Albertelli, M.A.2    O'Mahony, O.A.3
  • 53
    • 0028944138 scopus 로고
    • In vivo amplif-cation of the androgen receptor gene and progression of human prostate cancer
    • Visakorpi T, Hyytinen E, Koivisto P et al. In vivo amplif-cation of the androgen receptor gene and progression of human prostate cancer. Nat Genet 1995; 9(4):401-406.
    • (1995) Nat Genet , vol.9 , Issue.4 , pp. 401-406
    • Visakorpi, T.1    Hyytinen, E.2    Koivisto, P.3
  • 54
    • 0030333504 scopus 로고    scopus 로고
    • Androgen receptor gene amplifcation: A novel molecular mechanism for endocrine therapy resistance in human prostate cancer
    • Koivisto P, Visakorpi T, Kallioniemi OP. Androgen receptor gene amplifcation: a novel molecular mechanism for endocrine therapy resistance in human prostate cancer. Scand J Clin Lab Invest Suppl 1996; 226:57-63.
    • (1996) Scand J Clin Lab Invest Suppl , vol.226 , pp. 57-63
    • Koivisto, P.1    Visakorpi, T.2    Kallioniemi, O.P.3
  • 55
    • 0034656678 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization evaluation of c-myc and androgen receptor gene amplifcation and chromosomal anomalies in prostate cancer in Japanese patients
    • Miyoshi Y, Uemura H, Fujinami K et al. Fluorescence in situ hybridization evaluation of c-myc and androgen receptor gene amplifcation and chromosomal anomalies in prostate cancer in Japanese patients. Prostate 2000; 43(3):225-232.
    • (2000) Prostate , vol.43 , Issue.3 , pp. 225-232
    • Miyoshi, Y.1    Uemura, H.2    Fujinami, K.3
  • 56
  • 57
    • 0031047767 scopus 로고    scopus 로고
    • Androgen receptor gene amplifcation in a recurrent prostate cancer after monotherapy with the nonsteroidal potent antiandrogen Casodex (bicalutamide) with a subsequent favorable response to maximal androgen blockade
    • Palmberg C, Koivisto P, Hyytinen E et al. Androgen receptor gene amplifcation in a recurrent prostate cancer after monotherapy with the nonsteroidal potent antiandrogen Casodex (bicalutamide) with a subsequent favorable response to maximal androgen blockade. Eur Urol 1997; 31(2):216-219.
    • (1997) Eur Urol , vol.31 , Issue.2 , pp. 216-219
    • Palmberg, C.1    Koivisto, P.2    Hyytinen, E.3
  • 58
    • 0029011116 scopus 로고
    • Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
    • Taplin ME, Bubley GJ, Shuster TD et al. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med 1995; 332(21):1393-1398.
    • (1995) N Engl J Med , vol.332 , Issue.21 , pp. 1393-1398
    • Taplin, M.E.1    Bubley, G.J.2    Shuster, T.D.3
  • 59
    • 0033152164 scopus 로고    scopus 로고
    • Selection for androgen receptor mutations in prostate cancers treated with andro-gen antagonist
    • Taplin ME, Bubley GJ, Ko YJ et al. Selection for androgen receptor mutations in prostate cancers treated with andro-gen antagonist. Cancer Res 1999; 59(11):2511-2515.
    • (1999) Cancer Res , vol.59 , Issue.11 , pp. 2511-2515
    • Taplin, M.E.1    Bubley, G.J.2    Ko, Y.J.3
  • 60
    • 0029915052 scopus 로고    scopus 로고
    • Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence
    • Tilley WD, Buchanan G, Hickey TE, Bentel JM. Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence. Clin Cancer Res 1996; 2(2):277-285.
    • (1996) Clin Cancer Res , vol.2 , Issue.2 , pp. 277-285
    • Tilley, W.D.1    Buchanan, G.2    Hickey, T.E.3    Bentel, J.M.4
  • 61
    • 8244262043 scopus 로고    scopus 로고
    • Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells
    • Tan J, Sharief Y, Hamil KG et al. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells. Mol Endocrinol 1997; 11(4): 450-459.
    • (1997) Mol Endocrinol , vol.11 , Issue.4 , pp. 450-459
    • Tan, J.1    Sharief, Y.2    Hamil, K.G.3
  • 62
    • 0034652723 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Marcelli M, Ittmann M, Mariani S et al. Androgen receptor mutations in prostate cancer. Cancer Res 2000; 60(4): 944-949.
    • (2000) Cancer Res , vol.60 , Issue.4 , pp. 944-949
    • Marcelli, M.1    Ittmann, M.2    Mariani, S.3
  • 63
    • 0030265868 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Barrack ER. Androgen receptor mutations in prostate cancer. Mt Sinai J Med 1996; 63(5-6):403-412.
    • (1996) Mt Sinai J Med , vol.63 , Issue.5-6 , pp. 403-412
    • Barrack, E.R.1
  • 64
    • 0031035330 scopus 로고    scopus 로고
    • Androgen receptor gene mutations in prostate cancer. Implications for disease progression and therapy
    • Culig Z, Hobisch A, Hittmair A et al. Androgen receptor gene mutations in prostate cancer. Implications for disease progression and therapy. Drugs Aging 1997; 10(1):50-58.
    • (1997) Drugs Aging , vol.10 , Issue.1 , pp. 50-58
    • Culig, Z.1    Hobisch, A.2    Hittmair, A.3
  • 65
    • 0030979519 scopus 로고    scopus 로고
    • Androgen receptor gene mutations in prostate cancer]
    • Wang C, Uchida T. [Androgen receptor gene mutations in prostate cancer]. Nippon Hinyokika Gakkai Zasshi 1997; 88(5):550-556.
    • (1997) Nippon Hinyokika Gakkai Zasshi , vol.88 , Issue.5 , pp. 550-556
    • Wang, C.1    Uchida, T.2
  • 67
    • 0026652555 scopus 로고
    • Androgen receptor gene mutations in human prostate cancer
    • Newmark JR, Hardy DO, Tonb DC et al. Androgen receptor gene mutations in human prostate cancer. Proc Natl Acad Sci USA 1992; 89(14):6319-6323.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.14 , pp. 6319-6323
    • Newmark, J.R.1    Hardy, D.O.2    Tonb, D.C.3
  • 68
    • 0032695582 scopus 로고    scopus 로고
    • Androgen receptor gene mutations in hormone-refractory prostate cancer
    • Wallen MJ, Linja M, Kaartinen K, Schleutker J, Visakorpi T. Androgen receptor gene mutations in hormone-refractory prostate cancer. J Pathol 1999; 189(4):559-563.
    • (1999) J Pathol , vol.189 , Issue.4 , pp. 559-563
    • Wallen, M.J.1    Linja, M.2    Kaartinen, K.3    Schleutker, J.4    Visakorpi, T.5
  • 70
    • 0025347279 scopus 로고
    • Unusual specifcity of the androgen receptor in the human prostate tumor cell line LNCaP: High affnity for progestagenic and estrogenic steroids
    • Veldscholte J, Voorhorst-Ogink MM, Bolt-de Vries J, van Rooij HC, Trapman J, Mulder E. Unusual specifcity of the androgen receptor in the human prostate tumor cell line LNCaP: high affnity for progestagenic and estrogenic steroids. Biochim Biophys Acta 1990; 1052(1):187-194.
    • (1990) Biochim Biophys Acta , vol.1052 , Issue.1 , pp. 187-194
    • Veldscholte, J.1    Voorhorst-Ogink, M.M.2    Bolt-De Vries, J.3    Van Rooij, H.C.4    Trapman, J.5    Mulder, E.6
  • 71
    • 0026446137 scopus 로고
    • Single base mutations in the human androgen receptor gene causing complete androgen insensitivity: Rapid detection by a modifed denaturing gradient gel electrophoresis technique
    • De BA, Quigley CA, Cariello NF et al. Single base mutations in the human androgen receptor gene causing complete androgen insensitivity: rapid detection by a modifed denaturing gradient gel electrophoresis technique. Mol Endocrinol 1992; 6(11):1909-1920.
    • (1992) Mol Endocrinol , vol.6 , Issue.11 , pp. 1909-1920
    • De Ba Quigley, C.A.1    Cariello, N.F.2
  • 72
    • 0026499337 scopus 로고
    • Point mutation in the steroid-binding domain of the androgen receptor gene in a family with complete androgen insensitivity syndrome (CAIS)
    • Jakubiczka S, Werder EA, Wieacker P. Point mutation in the steroid-binding domain of the androgen receptor gene in a family with complete androgen insensitivity syndrome (CAIS). Hum Genet 1992; 90(3):311-312.
    • (1992) Hum Genet , vol.90 , Issue.3 , pp. 311-312
    • Jakubiczka, S.1    Werder, E.A.2    Wieacker, P.3
  • 73
    • 0034454581 scopus 로고    scopus 로고
    • Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome
    • Ahmed SF, Cheng A, Dovey L et al. Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome. J Clin Endocrinol Metab 2000; 85(2):658-665.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.2 , pp. 658-665
    • Ahmed, S.F.1    Cheng, A.2    Dovey, L.3
  • 74
    • 0242404297 scopus 로고    scopus 로고
    • Novel point mutations in complete androgen insensi-tivity syndrome with incomplete mullerian regression: Two Taiwanese patients
    • Van YH, Lin JL, Huang SF, Luo CC, Hwang CS, Lo FS. Novel point mutations in complete androgen insensi-tivity syndrome with incomplete mullerian regression: two Taiwanese patients. Eur J Pediatr 2003; 162(11): 781-784.
    • (2003) Eur J Pediatr , vol.162 , Issue.11 , pp. 781-784
    • Van Yh Lin, J.L.1    Huang, S.F.2    Luo, C.C.3    Hwang, C.S.4    Lo, F.S.5
  • 75
    • 0036149960 scopus 로고    scopus 로고
    • Postnatal changes of T, LH, and FSH in 46, XY infants with mutations in the AR gene
    • Bouvattier C, Carel JC, Lecointre C et al. Postnatal changes of T, LH, and FSH in 46, XY infants with mutations in the AR gene. J Clin Endocrinol Metab 2002; 87(1):29-32.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.1 , pp. 29-32
    • Bouvattier, C.1    Carel, J.C.2    Lecointre, C.3
  • 76
    • 0028948168 scopus 로고
    • Prevalence of androgen receptor gene mutations in latent prostatic carcinomas from Japanese men
    • Takahashi H, Furusato M, Allsbrook WC, Jr. et al. Prevalence of androgen receptor gene mutations in latent prostatic carcinomas from Japanese men. Cancer Res 1995; 55(8):1621-1624.
    • (1995) Cancer Res , vol.55 , Issue.8 , pp. 1621-1624
    • Takahashi, H.1    Furusato, M.2    Allsbrook Jr., W.C.3
  • 77
    • 0035212580 scopus 로고    scopus 로고
    • Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide
    • Haapala K, Hyytinen ER, Roiha M et al. Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide. Lab Invest 2001; 81(12):1647-1651.
    • (2001) Lab Invest , vol.81 , Issue.12 , pp. 1647-1651
    • Haapala, K.1    Hyytinen, E.R.2    Roiha, M.3
  • 78
    • 0035300409 scopus 로고    scopus 로고
    • Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
    • Gregory CW, Johnson RT, Jr., Mohler JL, French FS, Wilson EM. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res 2001; 61(7):2892-2898.
    • (2001) Cancer Res , vol.61 , Issue.7 , pp. 2892-2898
    • Gregory, C.W.1    Johnson Jr., R.T.2    Mohler, J.L.3    French, F.S.4    Wilson, E.M.5
  • 79
    • 18644372239 scopus 로고    scopus 로고
    • Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics
    • Chen G, Wang X, Zhang S et al. Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics. Prostate 2005; 63(4):395-406.
    • (2005) Prostate , vol.63 , Issue.4 , pp. 395-406
    • Chen, G.1    Wang, X.2    Zhang, S.3
  • 80
    • 34548057805 scopus 로고    scopus 로고
    • A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions
    • Jagla M, Feve M, Kessler P et al. A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions. Endocrinology 2007; 148(9):4334-4343
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4334-4343
    • Jagla, M.1    Feve, M.2    Kessler, P.3
  • 81
    • 17744378148 scopus 로고    scopus 로고
    • Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function
    • Buchanan G, Yang M, Harris JM et al. Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. Mol Endocrinol 2001; 15(1):46-56.
    • (2001) Mol Endocrinol , vol.15 , Issue.1 , pp. 46-56
    • Buchanan, G.1    Yang, M.2    Harris, J.M.3
  • 84
    • 0035831523 scopus 로고    scopus 로고
    • Ligand-and coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region
    • Wang Q, Lu J, Yong EL. Ligand-and coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region. J Biol Chem 2001; 276:7493-7499.
    • (2001) J Biol Chem , vol.276 , pp. 7493-7499
    • Wang, Q.1    Lu, J.2    Yong, E.L.3
  • 85
    • 0035834722 scopus 로고    scopus 로고
    • Androgen-induced NH2-and COOH-terminal Interaction Inhibits p160 coactivator recruitment by activation function 2
    • He B, Bowen NT, Minges JT, Wilson EM. Androgen-induced NH2-and COOH-terminal Interaction Inhibits p160 coactivator recruitment by activation function 2. J Biol Chem 2001; 276(45):42293-42301.
    • (2001) J Biol Chem , vol.276 , Issue.45 , pp. 42293-42301
    • He, B.1    Bowen, N.T.2    Minges, J.T.3    Wilson, E.M.4
  • 86
    • 1342325380 scopus 로고    scopus 로고
    • Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer
    • Gregory CW, Fei X, Ponguta LA et al. Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J Biol Chem 2004; 279(8): 7119-7130.
    • (2004) J Biol Chem , vol.279 , Issue.8 , pp. 7119-7130
    • Gregory, C.W.1    Fei, X.2    Ponguta, L.A.3
  • 87
    • 7944234374 scopus 로고    scopus 로고
    • HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
    • Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell 2004; 6(5):517-527.
    • (2004) Cancer Cell , vol.6 , Issue.5 , pp. 517-527
    • Mellinghoff, I.K.1    Vivanco, I.2    Kwon, A.3    Tran, C.4    Wongvipat, J.5    Sawyers, C.L.6
  • 88
    • 16344363218 scopus 로고    scopus 로고
    • Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth
    • Gregory CW, Whang YE, McCall W et al. Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. Clin Cancer Res 2005; 11(5): 1704-1712.
    • (2005) Clin Cancer Res , vol.11 , Issue.5 , pp. 1704-1712
    • Gregory, C.W.1    Whang, Y.E.2    McCall, W.3
  • 89
    • 17144400795 scopus 로고    scopus 로고
    • Inhibition of HER-2/neu kinase impairs androgen receptor recruitment to the androgen responsive enhancer
    • Liu Y, Majumder S, McCall W et al. Inhibition of HER-2/neu kinase impairs androgen receptor recruitment to the androgen responsive enhancer. Cancer Res 2005; 65(8): 3404-3409.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3404-3409
    • Liu, Y.1    Majumder, S.2    McCall, W.3
  • 90
    • 34347263425 scopus 로고    scopus 로고
    • Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation
    • Mahajan NP, Liu Y, Majumder S et al. Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation. Proc Natl Acad Sci USA 2007; 104(20):8438-8443.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.20 , pp. 8438-8443
    • Mahajan, N.P.1    Liu, Y.2    Majumder, S.3
  • 91
    • 51049107084 scopus 로고    scopus 로고
    • Site specifc androgen receptor serine phosphorylation linked to epidermal growth factor dependent growth of castration-recurrent prostate cancer
    • Ponguta LA, Gregory CW, French FS, Wilson EM. Site specifc androgen receptor serine phosphorylation linked to epidermal growth factor dependent growth of castration-recurrent prostate cancer. J Biol Chem 2008; 283(30): 20989-21001.
    • (2008) J Biol Chem , vol.283 , Issue.30 , pp. 20989-21001
    • Ponguta, L.A.1    Gregory, C.W.2    French, F.S.3    Wilson, E.M.4
  • 92
    • 0242290354 scopus 로고    scopus 로고
    • Activation of phosphati-dylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src
    • Sun M, Yang L, Feldman RI et al. Activation of phosphati-dylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src. J Biol Chem 2003; 278(44):42992-43000.
    • (2003) J Biol Chem , vol.278 , Issue.44 , pp. 42992-43000
    • Sun, M.1    Yang, L.2    Feldman, R.I.3
  • 93
    • 33749445413 scopus 로고    scopus 로고
    • Regulation of androgen receptor activity by tyrosine phosphorylation
    • Guo Z, Dai B, Jiang T et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell 2006; 10(4):309-319.
    • (2006) Cancer Cell , vol.10 , Issue.4 , pp. 309-319
    • Guo, Z.1    Dai, B.2    Jiang, T.3
  • 94
    • 48549089747 scopus 로고    scopus 로고
    • Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
    • Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008; 68(13):5469-5477.
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5469-5477
    • Dehm, S.M.1    Schmidt, L.J.2    Heemers, H.V.3    Vessella, R.L.4    Tindall, D.J.5
  • 95
    • 0842311632 scopus 로고    scopus 로고
    • The androgen axis in recurrent prostate cancer
    • Mohler JL, Gregory CW, Ford OH, III et al. The androgen axis in recurrent prostate cancer. Clin Cancer Res 2004; 10(2):440-448.
    • (2004) Clin Cancer Res , vol.10 , Issue.2 , pp. 440-448
    • Mohler, J.L.1    Gregory, C.W.2    Ford Iii., O.H.3
  • 96
    • 33645056171 scopus 로고    scopus 로고
    • Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
    • Stanbrough M, Bubley GJ, Ross K et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006; 66(5):2815-2825.
    • (2006) Cancer Res , vol.66 , Issue.5 , pp. 2815-2825
    • Stanbrough, M.1    Bubley, G.J.2    Ross, K.3
  • 97
    • 51049098138 scopus 로고    scopus 로고
    • Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
    • Locke JA, Guns ES, Lubik AA et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008; 68(15):6407-6415.
    • (2008) Cancer Res , vol.68 , Issue.15 , pp. 6407-6415
    • Locke, J.A.1    Guns, E.S.2    Lubik, A.A.3
  • 98
    • 0020577565 scopus 로고
    • Ketoconazole: A novel and rapid treatment for advanced prostatic cancer
    • Trachtenberg J, Halpern N, Pont A. Ketoconazole: a novel and rapid treatment for advanced prostatic cancer. J Urol 1983; 130(1):152-153.
    • (1983) J Urol , vol.130 , Issue.1 , pp. 152-153
    • Trachtenberg, J.1    Halpern, N.2    Pont, A.3
  • 99
    • 0021167082 scopus 로고
    • Ketoconazole therapy for advanced prostate cancer
    • Trachtenberg J, Pont A. Ketoconazole therapy for advanced prostate cancer. Lancet 1984; 2(8400):433-435.
    • (1984) Lancet , vol.2 , Issue.8400 , pp. 433-435
    • Trachtenberg, J.1    Pont, A.2
  • 100
    • 1842457650 scopus 로고    scopus 로고
    • Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase III trial (CALGB 9583)
    • Small EJ, Halabi S, Dawson NA et al. Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583). J Clin Oncol 2004; 22(6): 1025-1033.
    • (2004) J Clin Oncol , vol.22 , Issue.6 , pp. 1025-1033
    • Small, E.J.1    Halabi, S.2    Dawson, N.A.3
  • 101
    • 53749090666 scopus 로고    scopus 로고
    • Phase i Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone acetate, con-frms that castration-resistant prostate cancer commonly remains hormone driven
    • Attard G, Reid AH, Yap TA et al. Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone acetate, con-frms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol 2008; 26(28): 4563-4571.
    • (2008) J Clin Oncol , vol.26 , Issue.28 , pp. 4563-4571
    • Attard, G.1    Reid, A.H.2    Yap, T.A.3
  • 102
    • 3042784503 scopus 로고    scopus 로고
    • Hormonal impact of the 17alpha-hydroxylase/C(17, 20)-lyase inhibitor abi-raterone acetate (CB7630) in patients with prostate cancer
    • O'Donnell A, Judson I, Dowsett M et al. Hormonal impact of the 17alpha-hydroxylase/C(17, 20)-lyase inhibitor abi-raterone acetate (CB7630) in patients with prostate cancer. Br J Cancer 2004; 90(12):2317-2325.
    • (2004) Br J Cancer , vol.90 , Issue.12 , pp. 2317-2325
    • O'Donnell, A.1    Judson, I.2    Dowsett, M.3
  • 103
    • 0032784653 scopus 로고    scopus 로고
    • The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription
    • Alen P, Claessens F, Verhoeven G, Rombauts W, Peeters B. The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription. Mol Cell Biol 1999; 19(9):6085-6097.
    • (1999) Mol Cell Biol , vol.19 , Issue.9 , pp. 6085-6097
    • Alen, P.1    Claessens, F.2    Verhoeven, G.3    Rombauts, W.4    Peeters, B.5
  • 104
    • 33846603663 scopus 로고    scopus 로고
    • Androgen receptor coregulators and their involvement in the development and progression of prostate cancer
    • Chmelar R, Buchanan G, Need EF, Tilley W, Greenberg NM. Androgen receptor coregulators and their involvement in the development and progression of prostate cancer. Int J Cancer 2007; 120(4):719-733.
    • (2007) Int J Cancer , vol.120 , Issue.4 , pp. 719-733
    • Chmelar, R.1    Buchanan, G.2    Need, E.F.3    Tilley, W.4    Greenberg, N.M.5
  • 105
    • 0035361340 scopus 로고    scopus 로고
    • A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
    • Gregory CW, He B, Johnson RT et al. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 2001; 61(11):4315-4319.
    • (2001) Cancer Res , vol.61 , Issue.11 , pp. 4315-4319
    • Gregory, C.W.1    He, B.2    Johnson, R.T.3
  • 106
    • 24744442616 scopus 로고    scopus 로고
    • Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression
    • Agoulnik IU, Vaid A, Bingman WE, III et al. Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res 2005; 65(17):7959-7967.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7959-7967
    • Agoulnik, I.U.1    Vaid, A.2    Bingman Iii., W.E.3
  • 107
    • 0033512783 scopus 로고    scopus 로고
    • The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1
    • Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG. The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1. Mol Cell Biol 1999; 19(12):8383-8392.
    • (1999) Mol Cell Biol , vol.19 , Issue.12 , pp. 8383-8392
    • Bevan, C.L.1    Hoare, S.2    Claessens, F.3    Heery, D.M.4    Parker, M.G.5
  • 108
    • 33751304953 scopus 로고    scopus 로고
    • Androgens modulate expression of transcription intermediary factor 2, an andro-gen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer
    • Agoulnik IU, Vaid A, Nakka M et al. Androgens modulate expression of transcription intermediary factor 2, an andro-gen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. Cancer Res 2006; 66(21):10594-10602.
    • (2006) Cancer Res , vol.66 , Issue.21 , pp. 10594-10602
    • Agoulnik, I.U.1    Vaid, A.2    Nakka, M.3
  • 109
    • 24744440805 scopus 로고    scopus 로고
    • SRC-3 is required for prostate cancer cell proliferation and survival
    • Zhou HJ, Yan J, Luo W et al. SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res 2005; 65(17):7976-7983.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7976-7983
    • Zhou, H.J.1    Yan, J.2    Luo, W.3
  • 110
    • 0032560555 scopus 로고    scopus 로고
    • Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells
    • Miyamoto H, Yeh S, Wilding G, Chang C. Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells. Proc Natl Acad Sci USA 1998; 95(13):7379-7384.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.13 , pp. 7379-7384
    • Miyamoto, H.1    Yeh, S.2    Wilding, G.3    Chang, C.4
  • 111
    • 0037693192 scopus 로고    scopus 로고
    • Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development
    • Halkidou K, Gnanapragasam VJ, Mehta PB et al. Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development. Oncogene 2003; 22(16): 2466-2477.
    • (2003) Oncogene , vol.22 , Issue.16 , pp. 2466-2477
    • Halkidou, K.1    Gnanapragasam, V.J.2    Mehta, P.B.3
  • 112
    • 0037421958 scopus 로고    scopus 로고
    • Overexpression of Cdc25B an androgen receptor coactiva-tor in prostate cancer
    • Ngan ES, Hashimoto Y, Ma ZQ, Tsai MJ, Tsai SY. Overexpression of Cdc25B, an androgen receptor coactiva-tor, in prostate cancer. Oncogene 2003; 22(5):734-739.
    • (2003) Oncogene , vol.22 , Issue.5 , pp. 734-739
    • Ngan, E.S.1    Hashimoto, Y.2    Ma, Z.Q.3    Tsai, M.J.4    Tsai, S.Y.5
  • 113
    • 34248184635 scopus 로고    scopus 로고
    • Androgen deprivation increases p300 expression in prostate cancer cells
    • Heemers HV, Sebo TJ, Debes JD et al. Androgen deprivation increases p300 expression in prostate cancer cells. Cancer Res 2007; 67(7):3422-3430.
    • (2007) Cancer Res , vol.67 , Issue.7 , pp. 3422-3430
    • Heemers, H.V.1    Sebo, T.J.2    Debes, J.D.3
  • 114
    • 11144355585 scopus 로고    scopus 로고
    • ART-27, an androgen receptor coactivator regulated in prostate development and cancer
    • Taneja SS, Ha S, Swenson NK et al. ART-27, an androgen receptor coactivator regulated in prostate development and cancer. J Biol Chem 2004; 279(14):13944-13952.
    • (2004) J Biol Chem , vol.279 , Issue.14 , pp. 13944-13952
    • Taneja, S.S.1    Ha, S.2    Swenson, N.K.3
  • 115
    • 0033583033 scopus 로고    scopus 로고
    • Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate
    • Fujimoto N, Yeh S, Kang HY et al. Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate. J Biol Chem 1999; 274(12):8316-8321.
    • (1999) J Biol Chem , vol.274 , Issue.12 , pp. 8316-8321
    • Fujimoto, N.1    Yeh, S.2    Kang, H.Y.3
  • 116
    • 0037013312 scopus 로고    scopus 로고
    • Suppression of androgen receptor transactivation by Pyk2 via interaction and phos-phorylation of the ARA55 coregulator
    • Wang X, Yang Y, Guo X et al. Suppression of androgen receptor transactivation by Pyk2 via interaction and phos-phorylation of the ARA55 coregulator. J Biol Chem 2002; 277(18):15426-15431.
    • (2002) J Biol Chem , vol.277 , Issue.18 , pp. 15426-15431
    • Wang, X.1    Yang, Y.2    Guo, X.3
  • 117
    • 2642673582 scopus 로고    scopus 로고
    • Beta-catenin mutations in human prostate cancer
    • Voeller HJ, Truica CI, Gelmann EP. Beta-catenin mutations in human prostate cancer. Cancer Res 1998; 58(12): 2520-2523.
    • (1998) Cancer Res , vol.58 , Issue.12 , pp. 2520-2523
    • Voeller, H.J.1    Truica, C.I.2    Gelmann, E.P.3
  • 118
    • 0033663862 scopus 로고    scopus 로고
    • Detection and analysis of beta-catenin mutations in prostate cancer
    • Chesire DR, Ewing CM, Sauvageot J, Bova GS, Isaacs WB. Detection and analysis of beta-catenin mutations in prostate cancer. Prostate 2000; 45(4):323-334.
    • (2000) Prostate , vol.45 , Issue.4 , pp. 323-334
    • Chesire, D.R.1    Ewing, C.M.2    Sauvageot, J.3    Bova, G.S.4    Isaacs, W.B.5
  • 119
    • 0030118622 scopus 로고    scopus 로고
    • APC gene mutations in human prostate cancer
    • Watanabe M, Kakiuchi H, Kato H et al. APC gene mutations in human prostate cancer. Jpn J Clin Oncol 1996; 26(2):77-81.
    • (1996) Jpn J Clin Oncol , vol.26 , Issue.2 , pp. 77-81
    • Watanabe, M.1    Kakiuchi, H.2    Kato, H.3
  • 120
    • 18344363708 scopus 로고    scopus 로고
    • APC/CTNNB1 (beta-catenin) pathway alterations in human prostate cancers
    • Gerstein AV, Almeida TA, Zhao G et al. APC/CTNNB1 (beta-catenin) pathway alterations in human prostate cancers. Genes Chromosomes Cancer 2002; 34(1):9-16.
    • (2002) Genes Chromosomes Cancer , vol.34 , Issue.1 , pp. 9-16
    • Gerstein, A.V.1    Almeida, T.A.2    Zhao, G.3
  • 121
    • 35948929442 scopus 로고    scopus 로고
    • High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients
    • Henrique R, Ribeiro FR, Fonseca D et al. High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients. Clin Cancer Res 2007; 13(20):6122-6129.
    • (2007) Clin Cancer Res , vol.13 , Issue.20 , pp. 6122-6129
    • Henrique, R.1    Ribeiro, F.R.2    Fonseca, D.3
  • 122
    • 30944461586 scopus 로고    scopus 로고
    • PTEN and GSK3beta: Key regulators of progression to androgen-independent prostate cancer
    • Mulholland DJ, Dedhar S, Wu H, Nelson CC. PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer. Oncogene 2006; 25(3): 329-337.
    • (2006) Oncogene , vol.25 , Issue.3 , pp. 329-337
    • Mulholland, D.J.1    Dedhar, S.2    Wu, H.3    Nelson, C.C.4
  • 123
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
    • Rubinfeld B, Albert I, Porfri E, Fiol C, Munemitsu S, Polakis P. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996; 272(5264):1023-1026.
    • (1996) Science , vol.272 , Issue.5264 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 124
    • 5644271513 scopus 로고    scopus 로고
    • Cleavage of beta-catenin by calpain in prostate and mammary tumor cells
    • Rios-Doria J, Kuefer R, Ethier SP, Day ML. Cleavage of beta-catenin by calpain in prostate and mammary tumor cells. Cancer Res 2004; 64(20):7237-7240.
    • (2004) Cancer Res , vol.64 , Issue.20 , pp. 7237-7240
    • Rios-Doria, J.1    Kuefer, R.2    Ethier, S.P.3    Day, M.L.4
  • 125
    • 0034283030 scopus 로고    scopus 로고
    • Beta-catenin affects androgen receptor transcriptional activity and ligand speci-fcity
    • Truica CI, Byers S, Gelmann EP. Beta-catenin affects androgen receptor transcriptional activity and ligand speci-fcity. Cancer Res 2000; 60(17):4709-4713.
    • (2000) Cancer Res , vol.60 , Issue.17 , pp. 4709-4713
    • Truica, C.I.1    Byers, S.2    Gelmann, E.P.3
  • 126
    • 0037192870 scopus 로고    scopus 로고
    • Linking beta-catenin to androgen-signaling pathway
    • Yang F, Li X, Sharma M et al. Linking beta-catenin to androgen-signaling pathway. J Biol Chem 2002; 277(13): 11336-11344.
    • (2002) J Biol Chem , vol.277 , Issue.13 , pp. 11336-11344
    • Yang, F.1    Li, X.2    Sharma, M.3
  • 127
    • 0037124062 scopus 로고    scopus 로고
    • The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli
    • Mulholland DJ, Cheng H, Reid K, Rennie PS, Nelson CC. The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli. J Biol Chem 2002; 277(20):17933-17943.
    • (2002) J Biol Chem , vol.277 , Issue.20 , pp. 17933-17943
    • Mulholland, D.J.1    Cheng, H.2    Reid, K.3    Rennie, P.S.4    Nelson, C.C.5
  • 128
    • 0037036393 scopus 로고    scopus 로고
    • Liganded androgen receptor interaction with beta-catenin: Nuclear co-localization and modulation of transcriptional activity in neuronal cells
    • Pawlowski JE, Ertel JR, Allen MP et al. Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem 2002; 277(23):20702-20710.
    • (2002) J Biol Chem , vol.277 , Issue.23 , pp. 20702-20710
    • Pawlowski, J.E.1    Ertel, J.R.2    Allen, M.P.3
  • 129
    • 0037369953 scopus 로고    scopus 로고
    • Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription
    • Song LN, Herrell R, Byers S, Shah S, Wilson EM, Gelmann EP. Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription. Mol Cell Biol 2003; 23(5):1674-1687.
    • (2003) Mol Cell Biol , vol.23 , Issue.5 , pp. 1674-1687
    • Song, L.N.1    Herrell, R.2    Byers, S.3    Shah, S.4    Wilson, E.M.5    Gelmann, E.P.6
  • 130
    • 27844519279 scopus 로고    scopus 로고
    • Interaction of {beta}-Catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor
    • Song LN, Gelmann EP. Interaction of {beta}-Catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor. J Biol Chem 2005; 280(45):37853-37867.
    • (2005) J Biol Chem , vol.280 , Issue.45 , pp. 37853-37867
    • Song, L.N.1    Gelmann, E.P.2
  • 131
    • 0038475953 scopus 로고    scopus 로고
    • Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT
    • Liao G, Chen LY, Zhang A et al. Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT. J Biol Chem 2003; 278(7):5052-5061.
    • (2003) J Biol Chem , vol.278 , Issue.7 , pp. 5052-5061
    • Liao, G.1    Chen, L.Y.2    Zhang, A.3
  • 132
    • 0346025352 scopus 로고    scopus 로고
    • Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor
    • Song LN, Coghlan M, Gelmann EP. Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor. Mol Endocrinol 2004; 18(1): 70-85.
    • (2004) Mol Endocrinol , vol.18 , Issue.1 , pp. 70-85
    • Song, L.N.1    Coghlan, M.2    Gelmann, E.P.3
  • 133
    • 5044238220 scopus 로고    scopus 로고
    • Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells
    • Masiello D, Chen S Y, Xu Y et al. Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells. Mol Endocrinol 2004; 18(10):2388-2401.
    • (2004) Mol Endocrinol , vol.18 , Issue.10 , pp. 2388-2401
    • Masiello, D.1    Chen, S.Y.2    Xu, Y.3
  • 134
    • 34548595236 scopus 로고    scopus 로고
    • Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors
    • Hodgson MC, Astapova I, Hollenberg AN, Balk SP. Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors. Cancer Res 2007; 67(17):8388-8395.
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 8388-8395
    • Hodgson, M.C.1    Astapova, I.2    Hollenberg, A.N.3    Balk, S.P.4


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