Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two 2-pyridone inhibitors

Structure

Volumn 20, Issue 1, 2012, Pages 89-100

  Hirschbeck, Maria W ^a   Kuper, Jochen ^a   Lu, Hao ^b   Liu, Nina ^b   Neckles, Carla ^b   Shah, Sonam ^b   Wagner, Steffen ^c   Sotriffer, Christoph A ^c   Tonge, Peter J ^b   Kisker, Caroline ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; FABV ENOYL ACP REDUCTASE; OXIDOREDUCTASE; PT 172; PT 173; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; COMPLEX FORMATION; DRUG TARGETING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME STRUCTURE; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN FOLDING; YERSINIA PESTIS;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NAD; PROTEIN BINDING; PROTEIN CONFORMATION; PYRIDONES; SEQUENCE ALIGNMENT; YERSINIA PESTIS;

BACTERIA (MICROORGANISMS); YERSINIA PESTIS;

EID: 84855818674     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.07.019     Document Type: Article

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