Molecular basis for triclosan activity involves a flipping loop in the active site

Protein Science

Volumn 8, Issue 11, 1999, Pages 2529-2532

  Qiu, Xiayang ^a   Janson, Cheryl A ^a   Court, Robert I ^a   Smyth, Martin G ^a   Payne, David J ^a   Abdel Meguid, Sherin S ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Antibiotics; Crystal structure; Enoyl reductase; Fatty acid biosynthesis; NAD+; Triclosan

Indexed keywords

ANTIINFECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE; TRICLOSAN;

ARTICLE; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032721424     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.11.2529     Document Type: Article

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