Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK)

Biochemical Journal

Volumn 370, Issue 3, 2003, Pages 1055-1062

  Marrakchi, Hedia ^a   DeWolf, Walter E ^b   Quinn, Chad ^b   West, Joshua ^b   Polizzi, Brian J ^b   So, Chi Y ^b   Holmes, David J ^b   Reed, Shannon L ^b   Heath, Richard J ^a   Payne, David J ^b   Rock, Charles O ^a,c   Wallis, Nicola G ^b,d  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b GLAXOSMITHKLINE   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^d ASTEX PHARMACEUTICALS   (United Kingdom)

Author keywords

FabI; Fatty acid biosynthesis; Flavoprotein

Indexed keywords

BACTERIA; BIOCHEMISTRY; CATALYST ACTIVITY; FATTY ACIDS; GENES; METABOLISM;

ANAEROBIC ENERGY METABOLISM;

ENZYME KINETICS;

ACYL CARRIER PROTEIN; AMMONIA; FATTY ACID; FATTY ACID SYNTHASE; FLAVOPROTEIN; MUTANT PROTEIN; OXIDOREDUCTASE; PROTEIN FABK; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANAEROBIC METABOLISM; ARTICLE; BACILLUS SUBTILIS; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PURIFICATION; GENE DELETION; GENE EXPRESSION; MASS SPECTROMETRY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SEQUENCE; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NAD; NADH, NADPH OXIDOREDUCTASES; OXIDOREDUCTASES; SEQUENCE ALIGNMENT; STREPTOCOCCUS PNEUMONIAE;

BACILLI; BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); LACTOBACILLUS; POSIBACTERIA; PROKARYOTA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 0037444822     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021699     Document Type: Article

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