-
1
-
-
0026619273
-
Deviant energetic metabolism of glycolytic cancer cells
-
Baggetto LG: Deviant energetic metabolism of glycolytic cancer cells. Biochimie 74: 959-974, 1992.
-
(1992)
Biochimie
, vol.74
, pp. 959-974
-
-
Baggetto, L.G.1
-
2
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
DOI 10.1074/jbc.C000023200
-
Osthus RC, Shim H, Kim S, Li Q, Reddy R, Mukherjee M, Xu Y, Wonsey D, Lee LA and Dang CV: Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J Biol Chem 275: 21797-21800, 2000. (Pubitemid 30621745)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
Li, Q.4
Reddy, R.5
Mukherjee, M.6
Xu, Y.7
Wonsey, D.8
Lee, L.A.9
Dang, C.V.10
-
3
-
-
0017841405
-
Tumor mitochondria and the bioenergetics of cancer cells
-
Pedersen PL: Tumor mitochondria and the bioenergetics of cancer cells. Prog Exp Tumor Res 22: 190-274, 1978.
-
(1978)
Prog Exp Tumor Res
, vol.22
, pp. 190-274
-
-
Pedersen, P.L.1
-
4
-
-
0032539534
-
A unique glucose-dependent apoptotic pathway induced by c-Myc
-
DOI 10.1073/pnas.95.4.1511
-
Shim H, Chun YS, Lewis BC and Dang CV: A unique glucose-dependent apoptotic pathway induced by c-Myc. Proc Natl Acad Sci USA 95: 1511-1516, 1998. (Pubitemid 28103423)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.4
, pp. 1511-1516
-
-
Shim, H.1
Chun, Y.S.2
Lewis, B.C.3
Dang, C.V.4
-
5
-
-
0032945925
-
Modulation of oxygen consumption rate and vascular endothelial growth factor mRNA expression in human malignant glioma cells by hypoxia
-
lalunis-Turner MJ, Franko AJ and Parliament MB: Modulation of oxygen consumption rate and vascular endothelial growth factor mRNA expression in human malignant glioma cells by hypoxia. Br J Cancer 80: 104-109, 1999.
-
(1999)
Br J Cancer
, vol.80
, pp. 104-109
-
-
Lalunis-Turner, M.J.1
Franko, A.J.2
Parliament, M.B.3
-
6
-
-
0031731106
-
Variable presence of hypoxia in M006 human glioma spheroids and in spheroids and xenografts of clonally derived sublines
-
Franko AJ, Parliament MB, lalunis-Turner MJ and Wolokoff BG: Variable presence of hypoxia in M006 human glioma spheroids and in spheroids and xenografts of clonally derived sublines. Br J Cancer 78: 1261-1268, 1998. (Pubitemid 28495235)
-
(1998)
British Journal of Cancer
, vol.78
, Issue.10
, pp. 1261-1268
-
-
Franko, A.J.1
Parliament, M.B.2
Allalunis-Turner, M.J.3
Wolokoff, B.G.4
-
7
-
-
1442332088
-
Erythropoietin to treat anaemia in patients with head and neck cancer
-
Kaanders JH and van der Kogel AJ: Erythropoietin to treat anaemia in patients with head and neck cancer. Lancet 363: 78-79, 2004.
-
(2004)
Lancet
, vol.363
, pp. 78-79
-
-
Kaanders, J.H.1
Van Der Kogel, A.J.2
-
8
-
-
3142587028
-
Tumor microenvironmental physiology and its implications for radiation oncology
-
Vaupel P: Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol 14: 198-206, 2004.
-
(2004)
Semin Radiat Oncol
, vol.14
, pp. 198-206
-
-
Vaupel, P.1
-
9
-
-
50149097983
-
Hypoxia, HIF1 and glucose metabolism in the solid tumour
-
Denko NC: Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer 8: 705-713, 2008.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 705-713
-
-
Denko, N.C.1
-
10
-
-
34250788809
-
AKT/PKB Signaling: Navigating Downstream
-
DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
-
Manning BD and Cantley LC: AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274, 2007. (Pubitemid 46962095)
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
11
-
-
27944500725
-
Histology-based expression profiling yields novel prognostic markers in human glioblastoma
-
Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH and Louis DN: Histology-based expression profiling yields novel prognostic markers in human glioblastoma. J Neuropathol Exp Neurol 64: 948-955, 2005. (Pubitemid 41668924)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.11
, pp. 948-955
-
-
Dong, S.1
Nutt, C.L.2
Betensky, R.A.3
Stemmer-Rachamimov, A.O.4
Denko, N.C.5
Ligon, K.L.6
Rowitch, D.H.7
Louis, D.N.8
-
12
-
-
79958015593
-
Targeting metabolic remodeling in glioblastoma multiforme
-
Wolf A, Agnihotri S and Guha A: Targeting metabolic remodeling in glioblastoma multiforme. Oncotarget 1: 552-562, 2010.
-
(2010)
Oncotarget
, vol.1
, pp. 552-562
-
-
Wolf, A.1
Agnihotri, S.2
Guha, A.3
-
13
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL and Mischel PS: Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 353: 2012-2024, 2005. (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh, R.P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
14
-
-
9744221185
-
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
-
DOI 10.1016/j.molcel.2004.11.014, PII S1097276504006781
-
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB and Hay N: Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol Cell 16: 819-830, 2004. (Pubitemid 39586539)
-
(2004)
Molecular Cell
, vol.16
, Issue.5
, pp. 819-830
-
-
Majewski, N.1
Nogueira, V.2
Bhaskar, P.3
Coy, P.E.4
Skeen, J.E.5
Gottlob, K.6
Chandel, N.S.7
Thompson, C.B.8
Robey, R.B.9
Hay, N.10
-
15
-
-
0036510541
-
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
-
DOI 10.1074/jbc.M109950200
-
Pastorino JG, Shulga N and Hoek JB: Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J Biol Chem 277: 7610-7618, 2002. (Pubitemid 34953160)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.9
, pp. 7610-7618
-
-
Pastorino, J.G.1
Shulga, N.2
Hoek, J.B.3
-
16
-
-
0027081550
-
Brown adipose tissue: Magnetic resonance imaging and ultrastructural studies after transplantation in syngeneic rats
-
Dellagiacoma G, Sbarbati A, Rossi M, Zancanaro C, Benati D, Merigo F, Baldassarri A and Boicelli A: Brown adipose tissue: magnetic resonance imaging and ultrastructural studies after transplantation in syngeneic rats. Transplant Proc 24: 2986, 1992. (Pubitemid 23011792)
-
(1992)
Transplantation Proceedings
, vol.24
, Issue.6
, pp. 2986
-
-
Dellagiacoma, G.1
Sbarbati, A.2
Rossi, M.3
Zancanaro, C.4
Benati, D.5
Merigo, F.6
Baldassarri, A.7
Boicelli, A.8
-
17
-
-
84855653234
-
Mitochondrial DNA mutations
-
Springer, New York, NY
-
Singh KK: Mitochondrial DNA mutations. In: Aging, Disease and Cancer. Springer, New York, NY, 1998.
-
(1998)
Aging, Disease and Cancer
-
-
Singh, K.K.1
-
18
-
-
0024148694
-
Mitochondrial membrane potential in living cells
-
Chen LB: Mitochondrial membrane potential in living cells. Annu Rev Cell Biol 4: 155-181, 1988.
-
(1988)
Annu Rev Cell Biol
, vol.4
, pp. 155-181
-
-
Chen, L.B.1
-
19
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
DOI 10.1152/physrev.00013.2006
-
Kroemer G, Galluzzi L and Brenner C: Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163, 2007. (Pubitemid 46209992)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
20
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
DOI 10.1083/jcb.143.1.207
-
Goping IS, Gross A, Lavoie JN, Nguyen M, Jemmerson R, Roth K, Korsmeyer SJ and Shore GC: Regulated targeting of BAX to mitochondria. J Cell Biol 143: 207-215, 1998. (Pubitemid 28480529)
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.1
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
21
-
-
0032504575
-
Mitochondria as regulators of apoptosis: Doubt no more
-
DOI 10.1016/S0005-2728(98)00110-8, PII S0005272898001108
-
Susin SA, Zamzami N and Kroemer G: Mitochondria as regulators of apoptosis: doubt no more. Biochim Biophys Acta 1366: 151-165, 1998. (Pubitemid 28467029)
-
(1998)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1366
, Issue.1-2
, pp. 151-165
-
-
Susin, S.A.1
Zamzami, N.2
Kroemer, G.3
-
22
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
DOI 10.1038/nrc1478
-
Gatenby RA and Gillies RJ: Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899, 2004. (Pubitemid 39472955)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.11
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
23
-
-
34447547148
-
Regulation of tumor pH and the role of carbonic anhydrase 9
-
DOI 10.1007/s10555-007-9064-0, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
-
Swietach P, Vaughan-Jones RD and Harris AL: Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Rev 26: 299-310, 2007. (Pubitemid 47101667)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.2
, pp. 299-310
-
-
Swietach, P.1
Vaughan-Jones, R.D.2
Harris, A.L.3
-
24
-
-
33644870379
-
Oxidative phosphorylation dysfunction modulates expression of extracellular matrix - Remodeling genes and invasion
-
DOI 10.1093/carcin/bgi242
-
Van Waveren C, Sun Y, Cheung HS and Moraes CT: Oxidative phosphorylation dysfunction modulates expression of extracellular matrix-remodeling genes and invasion. Carcinogenesis 27: 409-418, 2006. (Pubitemid 43372870)
-
(2006)
Carcinogenesis
, vol.27
, Issue.3
, pp. 409-418
-
-
Van Waveren, C.1
Sun, Y.2
Cheung, H.S.3
Moraes, C.T.4
-
25
-
-
48549089006
-
The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function
-
Svineng G, Ravuri C, Rikardsen O, Huseby NE and Winberg JO: The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function. Connect. Tissue Res 49: 197-202, 2008.
-
(2008)
Connect. Tissue Res
, vol.49
, pp. 197-202
-
-
Svineng, G.1
Ravuri, C.2
Rikardsen, O.3
Huseby, N.E.4
Winberg, J.O.5
-
26
-
-
40949159866
-
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
-
DOI 10.1158/0008-5472.CAN-07-5259
-
Kumar B, Koul S, Khandrika L, Meacham RB and Koul HK: Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res 68: 1777-1785, 2008. (Pubitemid 351416563)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1777-1785
-
-
Kumar, B.1
Koul, S.2
Khandrika, L.3
Meacham, R.B.4
Koul, H.K.5
-
27
-
-
4043161974
-
Mitochondrial redox control of matrix metalloproteinases
-
DOI 10.1016/j.freeradbiomed.2004.06.008, PII S0891584904004617
-
Nelson KK and Melendez JA: Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med 37: 768-784, 2004. (Pubitemid 39078549)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.6
, pp. 768-784
-
-
Nelson, K.K.1
Melendez, J.A.2
-
28
-
-
77956597227
-
Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells
-
Chetty C, Lakka SS, Bhoopathi P, Gondi CS, Veeravalli KK, Fassett D, Klopfenstein JD, Dinh DH, Gujrati M and Rao JS: Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells. Mol Cancer Ther 9: 2605-2617, 2010.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2605-2617
-
-
Chetty, C.1
Lakka, S.S.2
Bhoopathi, P.3
Gondi, C.S.4
Veeravalli, K.K.5
Fassett, D.6
Klopfenstein, J.D.7
Dinh, D.H.8
Gujrati, M.9
Rao, J.S.10
-
29
-
-
77955374803
-
MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice
-
Veeravalli KK, Chetty C, Ponnala S, Gondi CS, Lakka SS, Fassett D, Klopfenstein JD, Dinh DH, Gujrati M and Rao JS: MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice. PLoS One 5: e11583, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Veeravalli, K.K.1
Chetty, C.2
Ponnala, S.3
Gondi, C.S.4
Lakka, S.S.5
Fassett, D.6
Klopfenstein, J.D.7
Dinh, D.H.8
Gujrati, M.9
Rao, J.S.10
-
30
-
-
17844399776
-
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme
-
DOI 10.1215/S1152851704000821
-
Giannini C, Sarkaria JN, Saito A, Uhm JH, Galanis E, Carlson BL, Schroeder MA and James CD: Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme. Neurooncology 7: 164-176, 2005. (Pubitemid 40590516)
-
(2005)
Neuro-Oncology
, vol.7
, Issue.2
, pp. 164-176
-
-
Giannini, C.1
Sarkaria, J.N.2
Saito, A.3
Uhm, J.H.4
Galanis, E.5
Carlson, B.L.6
Schroeder, M.A.7
James, C.D.8
-
31
-
-
33846199233
-
Hypoxia-inducible factors: central regulators of the tumor phenotype
-
DOI 10.1016/j.gde.2006.12.006, PII S0959437X06002401, Genetic and Cellular mechanisms of oncogenesis
-
Gordan JD and Simon MC: Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 17: 71-77, 2007. (Pubitemid 46109295)
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, Issue.1
, pp. 71-77
-
-
Gordan, J.D.1
Simon, M.C.2
-
32
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL: Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
33
-
-
33750220063
-
Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak
-
DOI 10.1093/jnci/djj395
-
Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y and Kitanaka C: Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak. J Natl Cancer Inst 98: 1462-1473, 2006. (Pubitemid 44605591)
-
(2006)
Journal of the National Cancer Institute
, vol.98
, Issue.20
, pp. 1462-1473
-
-
Tomiyama, A.1
Serizawa, S.2
Tachibana, K.3
Sakurada, K.4
Samejima, H.5
Kuchino, Y.6
Kitanaka, C.7
-
34
-
-
50649113948
-
Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy
-
Tabatabaei P, Bergstrom P, Henriksson R and Bergenheim AT: Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy. J Neurooncol 90: 35-39, 2008.
-
(2008)
J Neurooncol
, vol.90
, pp. 35-39
-
-
Tabatabaei, P.1
Bergstrom, P.2
Henriksson, R.3
Bergenheim, A.T.4
-
35
-
-
0025811821
-
Relationship of retinotopic ordering of axons in the optic pathway to the formation of visual maps in central targets
-
Simon DK and O'Leary DD: Relationship of retinotopic ordering of axons in the optic pathway to the formation of visual maps in central targets. J Comp Neurol 307: 393-404, 1991.
-
(1991)
J Comp Neurol
, vol.307
, pp. 393-404
-
-
Simon, D.K.1
O'Leary, D.D.2
-
36
-
-
20544449673
-
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
-
DOI 10.1038/sj.onc.1208622
-
Buzzai M, Bauer DE, Jones RG, Deberardinis RJ, Hatzivassiliou G, Elstrom RL and Thompson CB: The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene 24: 4165-4173, 2005. (Pubitemid 40961771)
-
(2005)
Oncogene
, vol.24
, Issue.26
, pp. 4165-4173
-
-
Buzzai, M.1
Bauer, D.E.2
Jones, R.G.3
DeBerardinis, R.J.4
Hatzivassiliou, G.5
Elstrom, R.L.6
Thompson, C.B.7
-
37
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
DOI 10.1158/0008-5472.CAN-03-2904
-
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM and Thompson CB: Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64: 3892-3899, 2004. (Pubitemid 38697301)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
Thompson, C.B.11
-
38
-
-
0037056002
-
Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
-
DOI 10.1016/S0005-2728(02)00248-7, PII S0005272802002487
-
Pedersen PL, Mathupala S, Rempel A, Geschwind JF and Ko YH: Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim Biophys Acta 1555: 14-20, 2002. (Pubitemid 35245999)
-
(2002)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1555
, Issue.1-3
, pp. 14-20
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
Geschwind, J.F.4
Ko, Y.H.5
-
39
-
-
79961127669
-
Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme
-
Wolf A, Agnihotri S, Munoz D and Guha A: Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme. Neurobiol Dis 44: 84-91, 2011.
-
(2011)
Neurobiol Dis
, vol.44
, pp. 84-91
-
-
Wolf, A.1
Agnihotri, S.2
Munoz, D.3
Guha, A.4
-
40
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
DOI 10.1101/gad.889901
-
Gottlob K, Majewski N, Kennedy S, Kandel E, Robey RB and Hay N: Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev 15: 1406-1418, 2001. (Pubitemid 32524647)
-
(2001)
Genes and Development
, vol.15
, Issue.11
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
41
-
-
0020517073
-
Diversity of metabolic patterns in human brain tumors: Enzymes of energy metabolism and related metabolites and cofactors
-
Lowry OH, Berger SJ, Carter JG, Chi MM, Manchester JK, Knor J and Pusateri ME: Diversity of metabolic patterns in human brain tumors: enzymes of energy metabolism and related metabolites and cofactors. J Neurochem 41: 994-1010, 1983. (Pubitemid 13018237)
-
(1983)
Journal of Neurochemistry
, vol.41
, Issue.4
, pp. 994-1010
-
-
Lowry, O.H.1
Berger, S.J.2
Carter, J.G.3
-
42
-
-
0022753696
-
Enzymes related to energy metabolism in human gliomas
-
Marzatico F, Curti D, Dagani F, Silvani V, Gaetani P, Butti G and Knerich R: Enzymes related to energy metabolism in human gliomas. J Neurosurg Sci 30: 129-132, 1986.
-
(1986)
J Neurosurg Sci
, vol.30
, pp. 129-132
-
-
Marzatico, F.1
Curti, D.2
Dagani, F.3
Silvani, V.4
Gaetani, P.5
Butti, G.6
Knerich, R.7
-
43
-
-
0029148289
-
Mitochondria-bound hexokinase as target for therapy of malignant gliomas
-
Oudard S, Poirson F, Miccoli L, Bourgeois Y, Vassault A, Poisson M, Magdelenat H, Dutrillaux B and Poupon MF: Mitochondria-bound hexokinase as target for therapy of malignant gliomas. Int J Cancer 62: 216-222, 1995.
-
(1995)
Int J Cancer
, vol.62
, pp. 216-222
-
-
Oudard, S.1
Poirson, F.2
Miccoli, L.3
Bourgeois, Y.4
Vassault, A.5
Poisson, M.6
Magdelenat, H.7
Dutrillaux, B.8
Poupon, M.F.9
-
44
-
-
60749108379
-
Regulation of autophagy by reactive oxygen species (ROS): Implications for cancer progression and treatment
-
Azad MB, Chen Y and Gibson SB: Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxid Redox Signal 11: 777-790, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 777-790
-
-
Azad, M.B.1
Chen, Y.2
Gibson, S.B.3
-
45
-
-
0034468736
-
Role of reactive oxygen species (ROS) in apoptosis induction
-
DOI 10.1023/A:1009616228304
-
Simon HU, Haj-Yehia A and Levi-Schaffer F: Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5: 415-418, 2000. (Pubitemid 32162623)
-
(2000)
Apoptosis
, vol.5
, Issue.5
, pp. 415-418
-
-
Simon, H.-U.1
Haj-Yehia, A.2
Levi-Schaffer, F.3
-
46
-
-
33847679043
-
0 cells
-
DOI 10.1016/j.mito.2006.11.005, PII S156772490600225X, Mitochondria and Life
-
Wochna A, Niemczyk E, Kurono C, Masaoka M, Kedzior J, Slominska E, Lipinski M and Wakabayashi T: A possible role of oxidative stress in the switch mechanism of the cell death mode from apoptosis to necrosis-studies on rho0 cells. Mitochondrion 7: 119-124, 2007. (Pubitemid 46351960)
-
(2007)
Mitochondrion
, vol.7
, Issue.1-2
, pp. 119-124
-
-
Wochna, A.1
Niemczyk, E.2
Kurono, C.3
Masaoka, M.4
Kedzior, J.5
Slominska, E.6
Lipinski, M.7
Wakabayashi, T.8
-
47
-
-
0036724159
-
Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury
-
Ahmad A, Ahmad S, Schneider BK, Allen CB, Chang LY and White CW: Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury. Am J Physiol Lung Cell Mol Physiol 283: L573-L584, 2002.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Ahmad, A.1
Ahmad, S.2
Schneider, B.K.3
Allen, C.B.4
Chang, L.Y.5
White, C.W.6
-
48
-
-
0030945198
-
Aerobic glycolysis by proliferating cells: A protective strategy against reactive oxygen species
-
Brand KA and Hermfisse U: Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J 11: 388-395, 1997. (Pubitemid 27193945)
-
(1997)
FASEB Journal
, vol.11
, Issue.5
, pp. 388-395
-
-
Brand, K.A.1
Hermfisse, U.2
-
49
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL and Dang CV: HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3: 177-185, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
50
-
-
34247614521
-
HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
-
DOI 10.1016/j.ccr.2007.04.001, PII S1535610807001158
-
Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, Dang CV and Semenza GL: HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11: 407-420, 2007. (Pubitemid 46670080)
-
(2007)
Cancer Cell
, vol.11
, Issue.5
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
Dang, C.V.7
Semenza, G.L.8
-
51
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR and Reed JC: Mitochondria and apoptosis. Science 281: 1309-1312, 1998. (Pubitemid 28406816)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
52
-
-
18744390391
-
+-ATP- synthase, suppresses the TNF-induced apoptosis
-
DOI 10.1038/sj.onc.1206053
-
Shchepina LA, Pletjushkina OY, Avetisyan AV, Bakeeva LE, Fetisova EK, Izyumov DS, Saprunova VB, Vyssokikh MY, Chernyak BV and Skulachev VP: Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene 21: 8149-8157, 2002. (Pubitemid 35454417)
-
(2002)
Oncogene
, vol.21
, Issue.53
, pp. 8149-8157
-
-
Shchepina, L.A.1
Pletjushkina, O.Y.2
Avetisyan, A.V.3
Bakeeva, L.E.4
Fetisova, E.K.5
Izyumov, D.S.6
Saprunova, V.B.7
Vyssokikh, M.Y.8
Chernyak, B.V.9
Skulachev, V.P.10
-
53
-
-
0031993196
-
1-ATPase proton pump is required for function of the proapoptotic protein bax in yeast and mammalian cells
-
Matsuyama S, Xu Q, Velours J and Reed JC: The mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells. Mol Cell 1: 327-336, 1998. (Pubitemid 128378881)
-
(1998)
Molecular Cell
, vol.1
, Issue.3
, pp. 327-336
-
-
Matsuyama, S.1
Xu, Q.2
Velours, J.3
Reed, J.C.4
-
54
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi Y, Shimizu S and Tsujimoto Y: Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57: 1835-1840, 1997. (Pubitemid 27209706)
-
(1997)
Cancer Research
, vol.57
, Issue.10
, pp. 1835-1840
-
-
Eguchi, Y.1
Shimizu, S.2
Tsujimoto, Y.3
-
55
-
-
0033781027
-
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
-
Goldstein JC, Waterhouse NJ, Juin P, Evan GI and Green DR: The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol 2: 156-162, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 156-162
-
-
Goldstein, J.C.1
Waterhouse, N.J.2
Juin, P.3
Evan, G.I.4
Green, D.R.5
-
56
-
-
0034024730
-
Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction
-
Ikemoto H, Tani E, Ozaki I, Kitagawa H and Arita N: Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction. Cell Death Differ 7: 511-520, 2000. (Pubitemid 30303606)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.6
, pp. 511-520
-
-
Ikemoto, H.1
Tani, E.2
Ozaki, I.3
Kitagawa, H.4
Arita, N.5
-
57
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
DOI 10.1084/jem.185.8.1481
-
Leist M, Single B, Castoldi AF, Kuhnle S and Nicotera P: Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med 185: 1481-1486, 1997. (Pubitemid 27187604)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.8
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
58
-
-
0942290437
-
In self-defence: Hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death
-
DOI 10.1042/BJ20031465
-
Azoulay-Zohar H, Israelson A, bu-Hamad S and Shoshan-Barmatz V: In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem J 377: 347-355, 2004. (Pubitemid 38142190)
-
(2004)
Biochemical Journal
, vol.377
, Issue.2
, pp. 347-355
-
-
Azoulay-Zohar, H.1
Israelson, A.2
Abu-Hamad, S.3
Shoshan-Barmatz, V.4
-
59
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
DOI 10.1038/sj.onc.1210220, PII 1210220
-
Adams JM and Cory S: The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337, 2007. (Pubitemid 46328466)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
60
-
-
34250760385
-
Selected technologies to control genes and their products for experimental and clinical purposes
-
DOI 10.1007/s00005-007-0025-7
-
Alexander HK, Booy EP, Xiao W, Ezzati P, Baust H and Los M: Selected technologies to control genes and their products for experimental and clinical purposes. Arch Immunol Ther Exp (Warsz.) 55: 139-149, 2007. (Pubitemid 46957404)
-
(2007)
Archivum Immunologiae et Therapiae Experimentalis
, vol.55
, Issue.3
, pp. 139-149
-
-
Alexander, H.K.1
Booy, E.P.2
Xiao, W.3
Ezzati, P.4
Baust, H.5
Los, M.6
-
61
-
-
33750619845
-
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
-
DOI 10.1016/j.ceb.2006.10.004, PII S0955067406001578
-
Antignani A and Youle RJ: How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr Opin Cell Biol 18: 685-689, 2006. (Pubitemid 44692478)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.6
, pp. 685-689
-
-
Antignani, A.1
Youle, R.J.2
-
62
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
DOI 10.1126/science.1059108
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ: Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730, 2001. (Pubitemid 32385543)
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.-Y.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
Macgregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
63
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
Wei MC, Lindsten T, Mootha VK, Weiler S, Gross A, Ashiya M, Thompson CB and Korsmeyer SJ: tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev 14: 2060-2071, 2000. (Pubitemid 30637355)
-
(2000)
Genes and Development
, vol.14
, Issue.16
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
64
-
-
33749543605
-
Non-irradiation-derived reactive oxygen species (ROS) and cancer: Therapeutic implications
-
DOI 10.1007/s00726-005-0271-8, Special issue: Focus on Neuropeptides in Anxiety and Depression
-
Agostinelli E and Seiler N: Non-irradiation-derived reactive oxygen species (ROS) and cancer: therapeutic implications. Amino Acids 31: 341-355, 2006. (Pubitemid 44537062)
-
(2006)
Amino Acids
, vol.31
, Issue.3
, pp. 341-355
-
-
Agostinelli, E.1
Seiler, N.2
-
65
-
-
77956186783
-
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
-
Hamanaka RB and Chandel NS: Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem Sci 35: 505-513, 2010.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 505-513
-
-
Hamanaka, R.B.1
Chandel, N.S.2
|