Intestinal patches with an immobilized solid-in-oil formulation for oral protein delivery

Acta Biomaterialia

Volumn 8, Issue 2, 2012, Pages 653-658

  Toorisaka, Eiichi ^a   Watanabe, Kikumi ^a   Ono, Hiroshige ^b   Hirata, Makoto ^a   Kamiya, Noriho ^c   Goto, Masahiro ^c  

^a OITA UNIVERSITY   (Japan)

^b SHUJITSU UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Intestinal patch system; Mucoadhesive polymer; Oral protein delivery; Protein pharmaceutics

Indexed keywords

BIOMOLECULES; CONTROLLED DRUG DELIVERY; CYTOLOGY; INSULIN; SURFACE ACTIVE AGENTS; TARGETED DRUG DELIVERY;

BIO-MOLECULAR; INTESTINAL MEMBRANES; INTESTINAL MUCOSA; INTESTINAL PATCH SYSTEM; MUCOADHESIVE POLYMERS; OIL FORMULATIONS; ORAL ADMINISTRATION; ORAL DELIVERY; ORAL PROTEIN DELIVERY; PROTEIN PHARMACEUTIC;

PROTEINS;

CARBOMER; CARBOXYMETHYLCELLULOSE; CHITOSAN; ETHYL CELLULOSE; HYDROXYETHYLCELLULOSE; HYDROXYPROPYLCELLULOSE; INSULIN; OIL; SUCROSE ESTER DERIVATIVE; SURFACTANT;

ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENZYMATIC DEGRADATION; GASTROINTESTINAL TRACT; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SAFETY; SOLID;

EID: 84855470718     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.09.023     Document Type: Article

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