Microemulsions for oral delivery of insulin: Design, development and evaluation in streptozotocin induced diabetic rats

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 2, 2010, Pages 159-169

  Sharma, G ^a   Wilson, K ^a   van der Walle, C F ^a   Sattar, N ^b   Petrie, J R ^b   Ravi Kumar, M N V ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Bioavailability; Insulin; Microemulsions; Oral delivery; Pharmacokinetics; Reverse micelles

Indexed keywords

DIDODECYLDIMETHYLAMMONIUM BROMIDE; GLUCOSE; INSULIN; PROPYLENE GLYCOL; SURFACTANT; TRIACETIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CONFORMATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG FORMULATION; FLUORESCENCE SPECTROSCOPY; IN VIVO STUDY; MALE; MICROEMULSION; NONHUMAN; PARTICLE SIZE; RAT; REVERSE MICELLE; SHEAR STRESS; STREPTOZOCIN DIABETES; TITRIMETRY; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; CIRCULAR DICHROISM; DIABETES MELLITUS, EXPERIMENTAL; EMULSIONS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; PROPYLENE GLYCOL; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, FLUORESCENCE; STREPTOZOCIN; TRIACETIN;

EID: 77957285711     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.07.002     Document Type: Article

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