An enteric-coated dry emulsion formulation for oral insulin delivery

Journal of Controlled Release

Volumn 107, Issue 1, 2005, Pages 91-96

  Toorisaka, Eiichi ^a   Hashida, Masakazu ^b   Kamiya, Noriho ^b   Ono, Hiroshige ^c   Kokazu, Yuko ^b   Goto, Masahiro ^b,d  

^a OITA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c SHUJITSU UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Dry emulsion; Enteric coating; Microcapsule; Oral protein delivery; Protein pharmaceuticals

Indexed keywords

ACIDITY; COATED MATERIALS; EMULSIONS; INSULIN; PH EFFECTS; SOLUTIONS; SURFACE ACTIVE AGENTS; VEGETABLE OILS;

ENTERIC-COATING; MICROCAPSULE; ORAL PROTEIN DELIVERY; PROTEIN PHARMACEUTICALS;

DRUG PRODUCTS;

ER 290; FLUORESCEIN ISOTHIOCYANATE; GLYCEROL; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; INSULIN; REBAMIPIDE; RICINOMACROGOL; SOYBEAN OIL; SUCROSE ERUCIC ESTER; SURFACTANT; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; WATER OIL CREAM;

ACIDITY; AQUEOUS SOLUTION; ARTICLE; CHEMICAL ENVIRONMENT; COMPLEX FORMATION; DRUG DELIVERY SYSTEM; ENTERIC COATED TABLET; FREEZE DRYING; GASTROINTESTINAL TRACT; PH; PRIORITY JOURNAL; SIMULATION; SOLID; SUSPENSION; TABLET FORMULATION;

ADMINISTRATION, ORAL; CAPSULES; CHEMISTRY, PHARMACEUTICAL; EMULSIONS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; INSULIN; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; PLANT OILS; SOLUTIONS; SURFACE-ACTIVE AGENTS; WATER;

EID: 24344446947     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.05.022     Document Type: Article

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