Oral delivery of insulin by using surface coating liposomes. Improvement of stability of insulin in GI tract

International Journal of Pharmaceutics

Volumn 157, Issue 1, 1997, Pages 73-80

  Iwanaga, Kazunori ^a   Ono, Satoshi ^a   Narioka, Kohji ^a   Morimoto, Kazuhiro ^a   Kakemi, Masawo ^a   Yamashita, Shinji ^b   Nango, Mamoru ^c   Oku, Naoto ^d  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

^d UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

GI tract; Insulin; Liposomes; Oral drug delivery; Stability; Surface coating

Indexed keywords

BOVINE INSULIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; LIPOSOME; MACROGOL; MUCIN; OCTADECYLAMINE; PEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; DRUG COATING; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; ENCAPSULATION; GLUCOSE BLOOD LEVEL; INTESTINE FLUID; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

EID: 0030801601     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00237-8     Document Type: Article

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