-
1
-
-
33646176246
-
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex
-
Ali M.M., Roe S.M., Vaughan C.K., Meyer P., Panaretou B., Piper P.W., Prodromou C., and Pearl L.H. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Nature 440 (2006) 1013-1017
-
(2006)
Nature
, vol.440
, pp. 1013-1017
-
-
Ali, M.M.1
Roe, S.M.2
Vaughan, C.K.3
Meyer, P.4
Panaretou, B.5
Piper, P.W.6
Prodromou, C.7
Pearl, L.H.8
-
2
-
-
0028589101
-
A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90
-
Aligue R., Akhavan-Niak H., and Russell P. A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90. EMBO J. 13 (1994) 6099-6106
-
(1994)
EMBO J.
, vol.13
, pp. 6099-6106
-
-
Aligue, R.1
Akhavan-Niak, H.2
Russell, P.3
-
3
-
-
21844458914
-
Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast
-
Asano S., Park J.E., Sakchaisri K., Yu L.R., Song S., Supavilai P., Veenstra T.D., and Lee K.S. Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast. EMBO J. 24 (2005) 2194-2204
-
(2005)
EMBO J.
, vol.24
, pp. 2194-2204
-
-
Asano, S.1
Park, J.E.2
Sakchaisri, K.3
Yu, L.R.4
Song, S.5
Supavilai, P.6
Veenstra, T.D.7
Lee, K.S.8
-
4
-
-
0027326257
-
Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins
-
Booher R.N., Deshaies R.J., and Kirschner M.W. Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins. EMBO J. 12 (1993) 3417-3426
-
(1993)
EMBO J.
, vol.12
, pp. 3417-3426
-
-
Booher, R.N.1
Deshaies, R.J.2
Kirschner, M.W.3
-
5
-
-
0031013723
-
In vivo analysis of the Hsp90 cochaperone Sti1 (p60)
-
Chang H.C., Nathan D.F., and Lindquist S. In vivo analysis of the Hsp90 cochaperone Sti1 (p60). Mol. Cell. Biol. 17 (1997) 318-325
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 318-325
-
-
Chang, H.C.1
Nathan, D.F.2
Lindquist, S.3
-
6
-
-
51049093018
-
Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90
-
Cunningham C.N., Krukenberg K.A., and Agard D.A. Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90. J. Biol. Chem. 283 (2008) 21170-21178
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21170-21178
-
-
Cunningham, C.N.1
Krukenberg, K.A.2
Agard, D.A.3
-
7
-
-
35848929277
-
Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase
-
Duval M., Le Boeuf F., Huot J., and Gratton J.P. Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase. Mol. Biol. Cell 18 (2007) 4659-4668
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4659-4668
-
-
Duval, M.1
Le Boeuf, F.2
Huot, J.3
Gratton, J.P.4
-
8
-
-
0028809690
-
Arrest at the G2/M transition of the cell cycle by protein-tyrosine phosphatase inhibition: studies on a neuronal and a glial cell line
-
Faure R., Vincent M., Dufour M., Shaver A., and Posner B.I. Arrest at the G2/M transition of the cell cycle by protein-tyrosine phosphatase inhibition: studies on a neuronal and a glial cell line. J. Cell. Biochem. 59 (1995) 389-401
-
(1995)
J. Cell. Biochem.
, vol.59
, pp. 389-401
-
-
Faure, R.1
Vincent, M.2
Dufour, M.3
Shaver, A.4
Posner, B.I.5
-
9
-
-
43249105354
-
p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity
-
Forafonov F., Toogun O.A., Grad I., Suslova E., Freeman B.C., and Picard D. p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Mol. Cell. Biol. 28 (2008) 3446-3456
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3446-3456
-
-
Forafonov, F.1
Toogun, O.A.2
Grad, I.3
Suslova, E.4
Freeman, B.C.5
Picard, D.6
-
10
-
-
0027073107
-
Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast
-
Garabedian M.J., and Yamamoto K.R. Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Mol. Biol. Cell 3 (1992) 1245-1257
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 1245-1257
-
-
Garabedian, M.J.1
Yamamoto, K.R.2
-
11
-
-
0035003608
-
Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1
-
Goes F.S., and Martin J. Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1. Eur. J. Biochem. 268 (2001) 2281-2289
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2281-2289
-
-
Goes, F.S.1
Martin, J.2
-
12
-
-
62049084010
-
Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine
-
Graf C., Stankiewicz M., Kramer G., and Mayer M.P. Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine. EMBO J. 28 (2009) 602-613
-
(2009)
EMBO J.
, vol.28
, pp. 602-613
-
-
Graf, C.1
Stankiewicz, M.2
Kramer, G.3
Mayer, M.P.4
-
13
-
-
0030863995
-
The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation
-
Grenert J.P., Sullivan W.P., Fadden P., Haystead T.A., Clark J., Mimnaugh E., Krutzsch H., Ochel H.J., Schulte T.W., Sausville E., et al. The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation. J. Biol. Chem. 272 (1997) 23843-23850
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23843-23850
-
-
Grenert, J.P.1
Sullivan, W.P.2
Fadden, P.3
Haystead, T.A.4
Clark, J.5
Mimnaugh, E.6
Krutzsch, H.7
Ochel, H.J.8
Schulte, T.W.9
Sausville, E.10
-
14
-
-
0037452658
-
Conservation of mechanisms controlling entry into mitosis: budding yeast wee1 delays entry into mitosis and is required for cell size control
-
Harvey S.L., and Kellogg D.R. Conservation of mechanisms controlling entry into mitosis: budding yeast wee1 delays entry into mitosis and is required for cell size control. Curr. Biol. 13 (2003) 264-275
-
(2003)
Curr. Biol.
, vol.13
, pp. 264-275
-
-
Harvey, S.L.1
Kellogg, D.R.2
-
15
-
-
0035110553
-
Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins
-
Hjorth-Sorensen B., Hoffmann E.R., Lissin N.M., Sewell A.K., and Jakobsen B.K. Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins. Mol. Microbiol. 39 (2001) 914-923
-
(2001)
Mol. Microbiol.
, vol.39
, pp. 914-923
-
-
Hjorth-Sorensen, B.1
Hoffmann, E.R.2
Lissin, N.M.3
Sewell, A.K.4
Jakobsen, B.K.5
-
16
-
-
40449089789
-
Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin
-
Holmes J.L., Sharp S.Y., Hobbs S., and Workman P. Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin. Cancer Res. 68 (2008) 1188-1197
-
(2008)
Cancer Res.
, vol.68
, pp. 1188-1197
-
-
Holmes, J.L.1
Sharp, S.Y.2
Hobbs, S.3
Workman, P.4
-
18
-
-
33846181647
-
Nucleotide-dependent interaction of Saccharomyces cerevisiae Hsp90 with the cochaperone proteins Sti1, Cpr6, and Sba1
-
Johnson J.L., Halas A., and Flom G. Nucleotide-dependent interaction of Saccharomyces cerevisiae Hsp90 with the cochaperone proteins Sti1, Cpr6, and Sba1. Mol. Cell. Biol. 27 (2007) 768-776
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 768-776
-
-
Johnson, J.L.1
Halas, A.2
Flom, G.3
-
19
-
-
0141484615
-
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal A., Thao L., Sensintaffar J., Zhang L., Boehm M.F., Fritz L.C., and Burrows F.J. A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 425 (2003) 407-410
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
Zhang, L.4
Boehm, M.F.5
Fritz, L.C.6
Burrows, F.J.7
-
20
-
-
50249168335
-
Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias
-
Kurokawa M., Zhao C., Reya T., and Kornbluth S. Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias. Mol. Cell. Biol. 28 (2008) 5494-5506
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5494-5506
-
-
Kurokawa, M.1
Zhao, C.2
Reya, T.3
Kornbluth, S.4
-
21
-
-
1642505452
-
Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase
-
Lee P., Shabbir A., Cardozo C., and Caplan A.J. Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase. Mol. Biol. Cell 15 (2004) 1785-1792
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1785-1792
-
-
Lee, P.1
Shabbir, A.2
Cardozo, C.3
Caplan, A.J.4
-
22
-
-
0024548919
-
Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II
-
Lees-Miller S.P., and Anderson C.W. Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II. J. Biol. Chem. 264 (1989) 2431-2437
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 2431-2437
-
-
Lees-Miller, S.P.1
Anderson, C.W.2
-
23
-
-
0344309014
-
The morphogenesis checkpoint: how yeast cells watch their figures
-
Lew D.J. The morphogenesis checkpoint: how yeast cells watch their figures. Curr. Opin. Cell Biol. 15 (2003) 648-653
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 648-653
-
-
Lew, D.J.1
-
24
-
-
33744779068
-
The function and regulation of budding yeast Swe1 in response to interrupted DNA synthesis
-
Liu H., and Wang Y. The function and regulation of budding yeast Swe1 in response to interrupted DNA synthesis. Mol. Biol. Cell 17 (2006) 2746-2756
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2746-2756
-
-
Liu, H.1
Wang, Y.2
-
25
-
-
0031795189
-
Hsp90 is required for pheromone signaling in yeast
-
Louvion J.F., Abbas-Terki T., and Picard D. Hsp90 is required for pheromone signaling in yeast. Mol. Biol. Cell 9 (1998) 3071-3083
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3071-3083
-
-
Louvion, J.F.1
Abbas-Terki, T.2
Picard, D.3
-
26
-
-
0027510249
-
Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15
-
McGowan C.H., and Russell P. Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15. EMBO J. 12 (1993) 75-85
-
(1993)
EMBO J.
, vol.12
, pp. 75-85
-
-
McGowan, C.H.1
Russell, P.2
-
27
-
-
31344474558
-
The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins
-
McLaughlin S.H., Sobott F., Yao Z.P., Zhang W., Nielsen P.R., Grossmann J.G., Laue E.D., Robinson C.V., and Jackson S.E. The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins. J. Mol. Biol. 356 (2006) 746-758
-
(2006)
J. Mol. Biol.
, vol.356
, pp. 746-758
-
-
McLaughlin, S.H.1
Sobott, F.2
Yao, Z.P.3
Zhang, W.4
Nielsen, P.R.5
Grossmann, J.G.6
Laue, E.D.7
Robinson, C.V.8
Jackson, S.E.9
-
28
-
-
0037352446
-
Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions
-
Meyer P., Prodromou C., Hu B., Vaughan C., Roe S.M., Panaretou B., Piper P.W., and Pearl L.H. Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions. Mol. Cell 11 (2003) 647-658
-
(2003)
Mol. Cell
, vol.11
, pp. 647-658
-
-
Meyer, P.1
Prodromou, C.2
Hu, B.3
Vaughan, C.4
Roe, S.M.5
Panaretou, B.6
Piper, P.W.7
Pearl, L.H.8
-
29
-
-
12744278245
-
Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach
-
Millson S.H., Truman A.W., Wolfram F., King V., Panaretou B., Prodromou C., Pearl L.H., and Piper P.W. Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach. Cell Stress Chaperones 9 (2004) 359-368
-
(2004)
Cell Stress Chaperones
, vol.9
, pp. 359-368
-
-
Millson, S.H.1
Truman, A.W.2
Wolfram, F.3
King, V.4
Panaretou, B.5
Prodromou, C.6
Pearl, L.H.7
Piper, P.W.8
-
30
-
-
34548131162
-
Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol
-
Millson S.H., Truman A.W., Racz A., Hu B., Panaretou B., Nuttall J., Mollapour M., Soti C., and Piper P.W. Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol. FEBS J. 274 (2007) 4453-4463
-
(2007)
FEBS J.
, vol.274
, pp. 4453-4463
-
-
Millson, S.H.1
Truman, A.W.2
Racz, A.3
Hu, B.4
Panaretou, B.5
Nuttall, J.6
Mollapour, M.7
Soti, C.8
Piper, P.W.9
-
31
-
-
0028806464
-
Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase
-
Mimnaugh E.G., Worland P.J., Whitesell L., and Neckers L.M. Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase. J. Biol. Chem. 270 (1995) 28654-28659
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28654-28659
-
-
Mimnaugh, E.G.1
Worland, P.J.2
Whitesell, L.3
Neckers, L.M.4
-
32
-
-
0032535245
-
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto R.I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 12 (1998) 3788-3796
-
(1998)
Genes Dev.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
33
-
-
63549104682
-
Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer
-
10.1371/journal.pcbi.1000323
-
Morra G., Verkhivker G., and Colombo G. Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer. PLoS Comput. Biol. 5 (2009) e1000323 10.1371/journal.pcbi.1000323
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Morra, G.1
Verkhivker, G.2
Colombo, G.3
-
34
-
-
0029037110
-
Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase
-
Nathan D.F., and Lindquist S. Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase. Mol. Cell. Biol. 15 (1995) 3917-3925
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3917-3925
-
-
Nathan, D.F.1
Lindquist, S.2
-
35
-
-
34248187981
-
Heat shock protein 90: the cancer chaperone
-
Neckers L. Heat shock protein 90: the cancer chaperone. J. Biosci. 32 (2007) 517-530
-
(2007)
J. Biosci.
, vol.32
, pp. 517-530
-
-
Neckers, L.1
-
36
-
-
0032538995
-
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis
-
Obermann W.M., Sondermann H., Russo A.A., Pavletich N.P., and Hartl F.U. In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J. Cell Biol. 143 (1998) 901-910
-
(1998)
J. Cell Biol.
, vol.143
, pp. 901-910
-
-
Obermann, W.M.1
Sondermann, H.2
Russo, A.A.3
Pavletich, N.P.4
Hartl, F.U.5
-
37
-
-
33746891507
-
4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution
-
Palmer B.D., Thompson A.M., Booth R.J., Dobrusin E.M., Kraker A.J., Lee H.H., Lunney E.A., Mitchell L.H., Ortwine D.F., Smaill J.B., et al. 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution. J. Med. Chem. 49 (2006) 4896-4911
-
(2006)
J. Med. Chem.
, vol.49
, pp. 4896-4911
-
-
Palmer, B.D.1
Thompson, A.M.2
Booth, R.J.3
Dobrusin, E.M.4
Kraker, A.J.5
Lee, H.H.6
Lunney, E.A.7
Mitchell, L.H.8
Ortwine, D.F.9
Smaill, J.B.10
-
38
-
-
0029686970
-
Isolation of yeast plasma membranes
-
Panaretou B., and Piper P. Isolation of yeast plasma membranes. Methods Mol. Biol. 53 (1996) 117-121
-
(1996)
Methods Mol. Biol.
, vol.53
, pp. 117-121
-
-
Panaretou, B.1
Piper, P.2
-
39
-
-
0032541344
-
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo
-
Panaretou B., Prodromou C., Roe S.M., O'Brien R., Ladbury J.E., Piper P.W., and Pearl L.H. ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo. EMBO J. 17 (1998) 4829-4836
-
(1998)
EMBO J.
, vol.17
, pp. 4829-4836
-
-
Panaretou, B.1
Prodromou, C.2
Roe, S.M.3
O'Brien, R.4
Ladbury, J.E.5
Piper, P.W.6
Pearl, L.H.7
-
40
-
-
0036931438
-
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1
-
Panaretou B., Siligardi G., Meyer P., Maloney A., Sullivan J.K., Singh S., Millson S.H., Clarke P.A., Naaby-Hansen S., Stein R., et al. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol. Cell 10 (2002) 1307-1318
-
(2002)
Mol. Cell
, vol.10
, pp. 1307-1318
-
-
Panaretou, B.1
Siligardi, G.2
Meyer, P.3
Maloney, A.4
Sullivan, J.K.5
Singh, S.6
Millson, S.H.7
Clarke, P.A.8
Naaby-Hansen, S.9
Stein, R.10
-
41
-
-
33746364784
-
Structure and mechanism of the Hsp90 molecular chaperone machinery
-
Pearl L.H., and Prodromou C. Structure and mechanism of the Hsp90 molecular chaperone machinery. Annu. Rev. Biochem. 75 (2006) 271-294
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 271-294
-
-
Pearl, L.H.1
Prodromou, C.2
-
42
-
-
28344446376
-
Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90
-
Picard D. Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90. Exp. Cell Res. 312 (2006) 198-204
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 198-204
-
-
Picard, D.1
-
43
-
-
0037413714
-
Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors
-
Piper P.W., Panaretou B., Millson S.H., Trumana A., Mollapour M., Pearl L.H., and Prodromou C. Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene 302 (2003) 165-170
-
(2003)
Gene
, vol.302
, pp. 165-170
-
-
Piper, P.W.1
Panaretou, B.2
Millson, S.H.3
Trumana, A.4
Mollapour, M.5
Pearl, L.H.6
Prodromou, C.7
-
45
-
-
0031444238
-
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
-
Prodromou C., Roe S.M., O'Brien R., Ladbury J.E., Piper P.W., and Pearl L.H. Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell 90 (1997) 65-75
-
(1997)
Cell
, vol.90
, pp. 65-75
-
-
Prodromou, C.1
Roe, S.M.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
46
-
-
35348858091
-
Post-translational modification of heat shock protein 90: impact on chaperone function
-
Scroggins B.T., and Neckers L. Post-translational modification of heat shock protein 90: impact on chaperone function. Expert Opin. Drug Discov. 2 (2007) 1403-1414
-
(2007)
Expert Opin. Drug Discov.
, vol.2
, pp. 1403-1414
-
-
Scroggins, B.T.1
Neckers, L.2
-
47
-
-
56849131626
-
Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle
-
Southworth D.R., and Agard D.A. Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle. Mol. Cell 32 (2008) 631-640
-
(2008)
Mol. Cell
, vol.32
, pp. 631-640
-
-
Southworth, D.R.1
Agard, D.A.2
-
48
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
-
Stebbins C.E., Russo A.A., Schneider C., Rosen N., Hartl F.U., and Pavletich N.P. Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell 89 (1997) 239-250
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
49
-
-
52249108496
-
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37
-
Vaughan C.K., Mollapour M., Smith J.R., Truman A., Hu B., Good V.M., Panaretou B., Neckers L., Clarke P.A., Workman P., et al. Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Mol. Cell 31 (2008) 886-895
-
(2008)
Mol. Cell
, vol.31
, pp. 886-895
-
-
Vaughan, C.K.1
Mollapour, M.2
Smith, J.R.3
Truman, A.4
Hu, B.5
Good, V.M.6
Panaretou, B.7
Neckers, L.8
Clarke, P.A.9
Workman, P.10
-
52
-
-
36848998942
-
Putting the heat on cancer
-
Workman P., and de Billy E. Putting the heat on cancer. Nat. Med. 13 (2007) 1415-1417
-
(2007)
Nat. Med.
, vol.13
, pp. 1415-1417
-
-
Workman, P.1
de Billy, E.2
-
53
-
-
0035980061
-
Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein
-
Zhao Y.G., Gilmore R., Leone G., Coffey M.C., Weber B., and Lee P.W. Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein. J. Biol. Chem. 276 (2001) 32822-32827
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32822-32827
-
-
Zhao, Y.G.1
Gilmore, R.2
Leone, G.3
Coffey, M.C.4
Weber, B.5
Lee, P.W.6
-
54
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
-
Zou J., Guo Y., Guettouche T., Smith D.F., and Voellmy R. Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell 94 (1998) 471-480
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
|