Rational design and evaluation of mammalian ribonuclease cytotoxins

Methods in Enzymology

Volumn 502, Issue , 2012, Pages 273-290

  Lomax, Jo E ^a   Eller, Chelcie H ^a   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cancer; Onconase; ptRNase; Ribonuclease inhibitor

Indexed keywords

CISPLATIN; CYTOTOXIN; DOCETAXEL; ERLOTINIB; MAMMALIAN PANCREATIC TYPE RIBONUCLEASE; PANCREATIC RIBONUCLEASE; RIBONUCLEASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASSAY; CANCER CELL; CANCER INHIBITION; CATALYSIS; CELL PROLIFERATION; CONJUGATION; CYTOTOXICITY; DNA SYNTHESIS; DRUG DESIGN; DRUG SCREENING; ENDOCYTOSIS; ENZYME ACTIVE SITE; ENZYME MODIFICATION; ERYTHROLEUKEMIA CELL; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HUMAN; INHIBITION KINETICS; INTERNALIZATION; LUNG NON SMALL CELL CANCER; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CARCINOMA; PROTEIN DEGRADATION; RNA CLEAVAGE; THERMOSTABILITY;

MAMMALIA;

EID: 84855407761     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-416039-2.00014-8     Document Type: Chapter

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