Tandemization Endows Bovine Pancreatic Ribonuclease with Cytotoxic Activity

Journal of Molecular Biology

Volumn 358, Issue 5, 2006, Pages 1305-1313

  Leich, Franziska ^a   Köditz, Jens ^a   Ulbrich Hofman, Renate ^a   Arnold, Ulrich ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

cytotoxicity; enzyme stability; protein engineering; ribonuclease A; tandem enzyme

Indexed keywords

CYTOTOXIC AGENT; ENZYME INHIBITOR; MONOMER; PANCREATIC RIBONUCLEASE; PEPTIDE; RIBONUCLEASE A;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CYTOSOL; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG STABILITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; ENZYME STRUCTURE; GENE DUPLICATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MELTING POINT; PRIORITY JOURNAL; RNA DEGRADATION; STEREOSPECIFICITY; TEMPERATURE;

BOVINAE;

EID: 33646095781     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.03.007     Document Type: Article

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