Site-specific folate conjugation to a cytotoxic protein

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 17, 2011, Pages 5029-5032

  Smith, Bryan D ^a,b   Higgin, Joshua J ^a,c   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Deciphera Pharmaceuticals LLC   (United States)

^c RTI INTERNATIONAL   (United States)

Author keywords

Bioconjugation; Cancer; Cytotoxin; Folic acid; Ribonuclease; Ribonuclease inhibitor

Indexed keywords

CYTOTOXIC FACTOR; FOLATE RECEPTOR; FOLIC ACID; RIBONUCLEASE A; RIBONUCLEASE INHIBITOR;

ARTICLE; CANCER CELL; CATALYSIS; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; PROTEIN TARGETING; SYNTHESIS;

ACYLATION; ANIMALS; CATALYSIS; CATALYTIC DOMAIN; CATTLE; FOLIC ACID; INHIBITORY CONCENTRATION 50; MASS SPECTROMETRY; PLACENTAL HORMONES;

BOVINAE; MAMMALIA;

EID: 80051802022     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.081     Document Type: Article

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