Cellular uptake of ribonuclease a relies on anionic glycans

Biochemistry

Volumn 49, Issue 50, 2010, Pages 10666-10673

  Chao, Tzu Yuan ^a   Lavis, Luke D ^a,b   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE PANCREATIC RIBONUCLEASE; CANCER CHEMOTHERAPEUTIC AGENTS; CELL SURFACE RECEPTORS; CELL SURFACES; CELLULAR BINDING; CELLULAR UPTAKE; CHONDROITIN SULFATES; GLYCANS; GLYCOSAMINOGLYCANS; HEPARAN SULFATES; HUMAN CELLS; HUMAN TUMOR CELLS; IN-VITRO; ONCONASE; PROTEOGLYCANS; RIBONUCLEASE A; RNASE A; SIALIC ACIDS;

CARBOXYLIC ACIDS; GLYCOPROTEINS; MAMMALS;

ELECTROPHORETIC MOBILITY;

CHONDROITIN SULFATE; GLYCOPROTEIN; HEPARAN SULFATE; RANPIRNASE; RIBONUCLEASE A; SIALIC ACID;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ELECTROPHORETIC MOBILITY; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; TUMOR CELL; ZETA POTENTIAL;

ANIMALS; ANIONS; CATTLE; CELL LINE; CELL PROLIFERATION; CHO CELLS; CHONDROITIN SULFATES; CHROMATOGRAPHY, AFFINITY; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; GLYCOPROTEINS; GLYCOSAMINOGLYCANS; HEPARITIN SULFATE; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR WEIGHT; N-ACETYLNEURAMINIC ACID; POLYSACCHARIDES; PROTEIN BINDING; RIBONUCLEASE, PANCREATIC; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

AMPHIBIA; BOVINAE; MAMMALIA;

EID: 78650394311     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1013485     Document Type: Article

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