Endowing Human Pancreatic Ribonuclease with Toxicity for Cancer Cells

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43095-43102

  Leland, Peter A ^a   Staniszewski, Kristine E ^a   Kim, Byung Moon ^a,b   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMOTHERAPY; PROTEINS; TOXICITY; TUMORS;

CYTOTOXICITY;

BIOCHEMISTRY;

INHIBITOR PROTEIN; PANCREATIC RIBONUCLEASE; RANPIRNASE; RIBONUCLEASE INHIBITOR PROTEIN; UNCLASSIFIED DRUG; AMINO ACID; ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; CYSTEINE; DISULFIDE; RIBONUCLEASE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CYTOTOXICITY; ENZYME CONFORMATION; ENZYME STABILITY; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; PRIORITY JOURNAL; AGAR GEL ELECTROPHORESIS; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CELL CULTURE; CELL DIVISION; CELL STRAIN K 562; CHEMISTRY; DOSE RESPONSE; KINETICS; LEUKEMIA; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; SPECTROFLUOROMETRY; TEMPERATURE;

AMPHIBIA;

AMINO ACID SEQUENCE; AMINO ACIDS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CYSTEINE; DISULFIDES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; KINETICS; LEUKEMIA; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RIBONUCLEASE, PANCREATIC; RIBONUCLEASES; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; TUMOR CELLS, CULTURED;

EID: 0035900671     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106636200     Document Type: Article

References (63)

1. Youle, R. J., and D'Alessio, G. (1997) in Ribonucleases: Structures and Functions (D'Alessio, G., and Riordan, J. F., eds) pp. 491-514, Academic Press, New York
2. Irie, M., Nitta, K., and Nonaka, T. (1998) Cell. Mol. Life Sci. 54, 775-784
3. Leland, P. A., and Raines, R. T. (2001) Chem. Biol. 8, 405-413
4. Mikulski, S. M., Grossman, A. M., Carter, P. W., Shogen, K., and Costanzi, J. J. (1993) Int. J. Oncol. 3, 57-64
5. Mikulski, S. M., Chun, H. G., Mittelman, A., Panella, T., Puccio, C. A., Shogen, K., and Costanzi, J. J. (1995) Int. J. Oncol. 6, 889-897
6. Wu, Y., Mikulski, S. M., Ardelt, W., Rybak, S. M., and Youle, R. J. (1993) J. Biol. Chem. 268, 10686-10693
7. Di Donato, A., Cafaro, V., and D'Alessio, G. (1994) J. Biol. Chem. 269, 17394-17396
8. Piccoli, R., Di Gaetano, S., De Lorenzo, C., Grauso, M., Monaco, C., Spalletti-Cernia, D., Laccetti, P., Cinátl, J., Matousek, J., and D'Alessio, G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7768-7773
9. Rybak, S. M., Saxena, S. K., Ackerman, E. J., and Youle, R. J. (1991) J. Biol. Chem. 266, 21202-21207
10. Newton, D. L., Ilercil, O., Laske, D. W., Oldfield, E., Rybak, S. M., and Youle, R. J. (1992) J. Biol. Chem. 267, 19572-19578
11. Psarras, K., Ueda, M., Yamamura, T., Ozawa, S., Kitajima, M., Aiso, S., Komatsu, S., and Seno, M. (1998) Protein Eng. 11, 1285-1292
12. Futami, J., Seno, M., Ueda, M., Tada, H., and Yamada, H. (1999) Protein Eng. 12, 1013-1019
13. Suwa, T., Ueda, M., Jinno, H., Ozawa, S., Kitagawa, Y., Ando, N., and Kitajima, M. (1999) Anticancer Res. 19, 4161-4165
14. Suzuki, M., Saxena, S. K., Boix, E., Prill, R. J., Vasandani, V. M., Ladner, J. E., Sung, C., and Youle, R. J. (1999) Nat. Biotechnal. 17, 265-270
15. Boix, E., Wu, Y., Vasandani, V. M., Saxena, S. K., Ardelt, W., Ladner, J., and Youle, R. J. (1996) J. Mol. Biol. 257, 992-1007
16. Gaur, D., Swaminathan, S., and Batra, J. K. (2001) J. Biol. Chem. 276, 24978-24984
17. Murthy, B. S., and Sirdeshmukh, R. (1992) Biochem. J. 281, 343-348
18. Kim, J.-S., Soucek, J., Matousek, J., and Raines, R. T. (1995) J. Biol. Chem. 270, 31097-31102
19. Hofsteenge, J. (1997) in Ribonucleases: Structures and Functions (D'Alessio, G., and Riordan, J. F., eds) pp. 621-658, Academic Press, New York
20. Leland, P. A., Schultz, L. W., Kim, B.-M., and Raines, R. T. (1998) Proc. Natl. Acad. Sci. U. S. A. 98, 10407-10412
21. Kelemen, B. R., Klink, T. A., Behlke, M. A., Eubanks, S. R., Leland, P. A., and Raines, R. T. (1999) Nucleic Acids Res. 27, 3696-3701
22. Wu, Y., Saxena, S. K., Ardelt, W., Gadina, M., Mikulski, S. M., De Lorenzo, V., D'Alessio, G., and Youle, R. J. (1995) J. Biol. Chem. 270, 17476-17481
23. Gill, S. C., and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326
24. Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., and Gray, T. (1995) Protein Sci. 4, 2411-2423
25. Klink, T. A., Woycechowsky, K. J., Taylor, K. M., and Raines, R. T. (2000) Eur. J. Biochem. 267, 566-572
26. Bretscher, L. E., Abel, R. L., and Raines, R. T. (2000) J. Biol. Chem. 275, 9893-9896
27. Klink, T. A., and Raines, R. T. (2000) J. Biol. Chem. 275, 17463-17467
28. Stone, S. R., and Hofsteenge, J. (1986) Biochemistry 25, 4622-4628
29. Kobe, B., and Deisenhofer, J. (1995) Nature 374, 183-186
30. Kobe, B., and Deisenhofer, J. (1996) J. Mol. Biol. 264, 1028-1043
31. Pous, J., Canals, A., Terzyan, S. S., Guasch, A., Benito, A., Ribó, M., Vilanova, M., and Coll, M. (2000) J. Mol. Biol. 303, 49-59
32. Pous, J., Mallorqui-Fernandez, G., Peracaula, R., Terzyan, S. S., Futami, J., Tada, H., Yamada, H., Seno, M., de Llorens, R., Gomis-Ruth, F. X., and Coll, M. (2001) Acta Crystallogr. Sect. D Biol. Crystallogr. 57, 498-505
33. Messmore, J. M., Fuchs, D. N., and Raines, R. T. (1995) J. Am. Chem. Soc. 117, 8057-8060
34. Trautwein, K., Holliger, P., Stackhouse, J., and Benner, S. A. (1991) FEBS Lett. 281, 275-277
35. Futami, J., Tada, H., Seno, M., Ishikami, S., and Yamada, H. (2000) J. Biochem. (Tokyo) 128, 245-250
36. Kim, J.-S., and Raines, R. T. (1993) Protein Sci. 2, 348-356
37. Bravo, J., Fernández, E., Ribó, M., de Llorens, R., and Cuchillo, C. M. (1994) Anal. Biochem. 219, 82-86
38. Canals, A., Ribó, M., Benito, A., Bosch, M., Mombelli, E., and Vilanova, M. (1999) Protein Express. Purif. 17, 169-181
39. Morrison, J. F., and Walsh, C. T. (1988) Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201-301
40. Sakakibara, F., Kawauchi, H., Takayanagi, G., and Ise, H. (1979) Cancer Res. 89, 1347-1352
41. Nitta, K., Takayanagi, G., Kawauchi, H., and Hakomori, S. (1987) Cancer Res. 47, 4877-4883
42. Okabe, Y., Katayama, N., Iwama, M., Watanabe, H., Ohgi, K., Irie, M., Nitta, K., Kawauchi, H., Takayanagi, Y., Oyama, F., Titani, K., Abe, Y., Okazaki, T., Inokuchi, N., and Koyama, T. (1991) J. Biochem. 109, 786-790
43. Saxena, S. K., Rybak, S. M., Winkler, G., Meade, H. M., McGray, P., Youle, R. J., and Ackerman, E. J. (1991) J. Biol. Chem. 266, 21208-21214
44. Teter, S. A., and Klionsky, D. J. (1999) Trends Cell Biol. 9, 428-431
45. Nitta, K., Oyama, F., Oyama, R., Sekiguchi, K., Kawauchi, H., Takayanagi, Y., Hakomori, S.-I., and Titani, K. (1993) Glycobiology 3, 37-45
46. Silver, P. A. (1991) Cell 64, 489-497
47. Moroianu, J., and Riordan, J. F. (1994) Biochem. Biophys. Res. Commun. 203, 1765-1772
48. Moroianu, J., and Riordan, J. F. (1994) Proc. Natl. Acad. Sci. U. S. A. 92, 1677-1681
49. Hu, G.-F., Xu, C., and Riordan, J. F. (2000) J. Cell. Biochem. 76, 452-462
50. Imperiali, B., and Hendrickson, T. L. (1995) Bioorg. Med. Chem. 3, 1565-1578
51. Ribó, M., Beintema, J. J., Osset, M., Fernández, E., Bravo, J., de Llorens, R., and Cuchillo, C. M. (1994) Biol. Chem. Hoppe-Seyler 375, 357-363
52. Parsell, D. A., and Sauer, R. T. (1989) J. Biol. Chem. 264, 7590-7595
53. Kowalski, J. M., Parekh, R. N., and Wittrup, K. D. (1998) Biochemistry 37, 1264-1273
54. Raines, R. T. (1999) in Enzymatic Mechanisms (Frey, P. A., and Northrop, D. B., eds) pp. 235-249, IOS Press, Washington, D. C.
55. Roth, J. S. (1967) Methods Cancer Res. 3, 153-242
56. Blackburn, P., and Moore, S. (1982) Enzymes 15, 317-433
57. Vasandani, V. M., Wu, Y.-N., Mikulski, S. M., Youle, R. J., and Sung, C. (1996) Cancer Res. 56, 4180-4186
58. Vasandani, V. M., Burris, J. A., and Sung, C. (1999) Cancer Chemother. Pharmacol. 44, 164-169
59. Mikulski, S. M., Viera, A., Ardelt, W., Menduke, H., and Shogen, K. (1990) Cell Tissue Kinet. 23, 237-246
60. Mikulski, S. M., Viera, A., and Shogen, K. (1992) Int. J. Oncol. 1, 779-785
61. Rybak, S. M., Pearson, J. W., Fogler, W. E., Volker, K., Spence, S. E., Newton, D. L., Mikulski, S. M., Ardelt, A., Riggs, C. W., Kung, H.-F., and Longo, D. L. (1996) J. Natl. Cancer Inst. 88, 747-753
62. Wlodawer, A., Anders, L. A., Sjölin, L., and Gilliland, G. L. (1988) Biochemistry 27, 2705-2717
63. Leland, P. A., Staniszewski, K. E., Kim, B.-M., and Raines, R. T. (2000) FEBS Lett. 477, 203-207