Antimony trichloride induces DNA damage and apoptosis in mammalian cells

Toxicology

Volumn 129, Issue 2-3, 1998, Pages 113-123

  Huang, H ^a   Shu, S C ^a   Shih, J H ^a   Kuo, C J ^a   Chiu, I D ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Antimony trichloride; Calcium accumulation; Delayed apoptosis; DNA damage

Indexed keywords

ANTIMONY; DNA FRAGMENT;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CARCINOGENESIS; CHO CELL; CONTROLLED STUDY; DNA DAMAGE; DRUG DETERMINATION; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE;

ANIMALS; ANTIMONY; APOPTOSIS; CALCIUM; CHLORIDES; CHO CELLS; CRICETINAE; DNA; DNA DAMAGE; DNA FRAGMENTATION; MICRONUCLEI, CHROMOSOME-DEFECTIVE;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA; RODENTIA;

EID: 0032555770     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(98)00073-0     Document Type: Article

References (42)

1. Arends M.J., Morris R.G., Wyllie A.H. Apoptosis. The role of the endonuclease. Am. J. Pathol. 136:1990;593-608.
2. Bortner C.D., Oldenburg N.B.E., Cidlowski J.A. The role of DNA fragmentation in apoptosis. Trends Cell Biol. 5:1995;21-26.
3. Carson, B.L., Ellis, H.V., McCann, J.L., 1986. Antimony. In: Toxicology and Biological Monitoring of Metals in Humans, Lewis, Chelsea, MI, pp. 21-26.
4. Cantoni O., Sestili P., Cattabeni F., Bellomo G., Pou S., Cohen M., Cerutti P. Calcium chelator Quin 2 prevents hydrogen peroxide-induced DNA breakage and cytotoxicity. Eur. J. Biochem. 182:1989;209-212.
5. Chelton C.F., Glowatz M., Mosovsky J.A. Chemical hazards in the semiconductor industry. IEEE Trans. Educ. 34(3):1991;269-288.
6. Christiansen N.O., Larsen C.S., Esmann V. A study on the role of protein kinase C and intracellular calcium in the activation of superoxide generation. Biochim. Biophys. Acta. 971:1988;317-324.
7. Darzynkiewicz Z., Bruno S., Del Bino G., Gorczyca W., Hotz M.A., Lassota P., Traganos F. Features of apoptotic cells measured by flow cytometry. Cytometry. 13:1992;795-808.
8. Duke R.C., Chervenak R., Cohen J.J. Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis. Proc. Natl. Acad. Sci. USA. 80:1983;6361-6365.
9. el Azzouzi B., Tsangaris G.T., Pellegrini O., Manuel Y., Benveniste J., Thomas Y. Cadmium induces apoptosis in a human T cell line. Toxicology. 88:1994;127-139.
10. Fenech M., Denham J., Francis W., Morley A. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int. J. Radiat. Biol. 57:1990;373-383.
11. Forrest V.J., Kang Y.-H., McClain D.E., Robinson D.H., Ramakrishnan N. Oxidative stress-induced apoptosis prevented by trolox. Free Radical Biol. Med. 16(6):1994;675-684.
12. Gebel T., Kevekordes S., Schaefer J., von Platen H., Dunkelberg H. Assessment of a possible genotoxic environmental risk in sheep bred on grounds with strongly elevated contents of mercy, arsenic and antimony. Mutat. Res. 368:1996;267-274.
13. Gebel T., Christensen S., Dunkelberg H. Comparative and environmental genotoxicity of antimony and arsenic. Anticancer Res. 17(4A):1997;2603-2607.
14. Groth D.H., Stettler L.E., Burg J.R., Busey W.E., Grant G.C., Wong L. Carcinogenic effects of antimony trioxide and antimony ore concentrate in rats. J. Toxicol. Environ. Health. 18:1986;607-626.
15. Hantson P., Leonard E.D., Crutzenfayt M.C., Leonard A., Vandercam B., Delaere B, Mahieu P. Cytogenetic observations after meglumine antimonate therapy for visceral Leishmaniasis. Pharmacotherapy. 16(5):1996;869-871.
16. Hockenbery D.M., Oltvai Z.N., Yin X.M., Milliman C.L., Korsmeyer S.J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 75:1993;241-251.
17. Jones R.D. Survey of antimony workers: mortality 1961-1992. Occup. Environ. Med. 51:1994;772-776.
18. Kastan M.B., Onyekwere O., Sidransky D., Vogelstein B., Craig R.W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311.
19. Kuroda K., Endo G., Okamoto A., Yoo Y.S., Horiguchi S. Genotoxicity of beryllium, gallium and antimony in short-term assays. Mutat. Res. 264:1991;163-170.
20. Leonard A., Gerber G.B. Mutagenicity, carcinogenicity and teratogenicity of antimony compounds. Mutat. Res. 366:1996;1-8.
21. Liu Y.C., Huang H. Lowering extracellular calcium content protects cells from arsenite-induced killing and micronuclei formation. Mutagenesis. 11:1996;75-78.
22. Liu Y.C., Huang H. Involvement of calcium-dependent protein kinase C in arsenite induced genotoxicity in Chinese hamster ovary cells. J. Cell. Biochem. 64:1997;423-433.
23. 2+-dependent endonuclease in apoptosis. Biochem. Biophys. Res. Commun. 190:1993;1097-1103.
24. Manning F.C., Blankenship L.J., Wise J.P., Xu J., Bridgewater L.C., Patierno S.R. Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis. Environ. Health Perspect. 102:1994;159-167.
25. 2+ and the stimulation of a nonlysosomal proteolytic system. J. Biol. Chem. 261:1986;14628-14635.
26. 2+ pool in liver nuclei. Proc. Natl. Acad. Sci. USA. 86:1990;6858-6862.
27. Nicotera P., Bellomo G., Orrenius S. Calcium-mediated mechanisms in chemically induced cell death. Annu. Rev. Pharmacol. Toxicol. 32:1992;449-470.
28. Oberhammer F., Wilson J.W., Dive C. et al. Apoptotic death in epithelial cells: cleavage of DNA to 300 and or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12:1993;3679-3684.
29. Orren D.K., Petersen L.N., Bohr V.A. A UV-responsive G2 checkpoint in rodent cells. Mol. Cell. Biol. 15:1995;3722-3730.
30. Rasmussen H., Barrett P.Q., Smallwood J., Bollag W., Isales C. Calcium ion as intracellular messenger and cellular toxin. Environ. Health Perspect. 84:1990;17-25.
31. Ross C.A., Meldolesi J., Milner T.A., Satoh T., Supattapone S., Snyder S.H. Inositol 1,4,5-triphosphate receptors localized to endoplasmic reticulum in cerebellar Purkinje neurons. Nature. 339:1989;468-470.
32. 2+ homeostasis in the gerbil hippocampus following brief transient ischemia. Brain Res. 364:1986;372-376.
33. Skehan P., Storeng R., Scudiero D. et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 82:1990;1107-1112.
34. Stokinger, H.E., 1981. The metals: 2 antimony, Sb. In: Clayton, G.D., Clayton, F.E. (Eds.), Patty's Industrial Hygiene and Toxicology, 3rd ed., volume IIA, Toxicology. Wiley-Interscience, New York, pp. 1505-1517.
35. Tirmenstein M.A., Plews P.I., Walker C.V., Woolery M.D., Wey H.E., Toraason M.A. Antimony-induced oxidative stress and toxicity in cultured cardiac myocytes. Toxicol. Appl. Pharmacol. 130:1995;41-47.
36. Tirmenstein M.A., Mathias P.I., Snawder J.E., Wey H.E., Toraason M. Antimony-induced alterations in thiol homeostasis and adenine nucleotide status in cultured cardiac myocytes. Toxicology. 119:1997;203-211.
37. 2+ mobilization during excitation-contraction in cultured cardiac myocytes exposed to antimony. Toxicol. Appl. Pharmacol. 146:1997;104-115.
38. Wang T.S., Huang H. Active oxygen species are involved in the induction of micronuclei by arsenite in Xrs-5 cells. Mutagenesis. 9:1994;253-257.
39. Wang T.S., Kuo C.F., Jan K.Y., Huang H. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species. J. Cell. Physiol. 169:1996;256-268.
40. Wang T.S., Shu Y.F., Liu Y.C., Jan K.Y., Huang H. Glutathione peroxidase and catalase modulate the genotoxicity of arsenite. Toxicology. 121:1997;229-237.
41. Wey H.E., Richards D., Tirmenstein M.A., Mathias P.I., Toraason M. The role of intracellular calcium in antimony-induced toxicity in cultured cardiac myocytes. Toxicol. Appl. Pharmacol. 145:1997;202-210.
42. Winship K.A. Toxicity of antimony and its compounds. Adv. Drug React. Acute Poison. Rev. 2:1987;67-90.