Retooling manganese(III) porphyrin-based peroxynitrite decomposition catalysts for selectivity and oral activity: A potential new strategy for treating chronic pain

Journal of Medicinal Chemistry

Volumn 54, Issue 24, 2011, Pages 8658-8669

  Rausaria, Smita ^a   Ghaffari, Mahsa M E ^a   Kamadulski, Andrew ^a   Rodgers, Kenny ^b   Bryant, Leesa ^c   Chen, Zhoumou ^c   Doyle, Tim ^c   Shaw, Michael J ^b   Salvemini, Daniela ^c   Neumann, William L ^a  

^a School of Pharmacy   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CARRAGEENAN; MANGANESE DERIVATIVE; MANGANESE TETRACYCLOHEXENYLPORPHYIN DERIVATIVE; PEROXYNITRITE; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TRANSPORT; HYPERALGESIA;

ADMINISTRATION, ORAL; ANALGESICS; ANIMALS; BORONIC ACIDS; CARRAGEENAN; CATALYSIS; CHRONIC PAIN; ELECTROCHEMISTRY; HYPERALGESIA; MANGANESE; METALLOPORPHYRINS; MICE; NEURALGIA; PEROXYNITROUS ACID; RATS; SCIATIC NERVE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE;

EID: 84055221776     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201233r     Document Type: Article

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