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Volumn 47, Issue 41, 2008, Pages 7896-7900

Amphiphilic/bipolar metallocorroles that catalyze the decomposition of reactive oxygen and nitrogen species, rescue lipoproteins from oxidative damage,and attenuate atherosclerosis in mice

Author keywords

Antioxidants; Atherosclerosis; Corroles; Iron; Manganese

Indexed keywords

CHEMICAL REACTIONS; LIPIDS; PROTEINS;

EID: 54749121956     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200801149     Document Type: Article
Times cited : (69)

References (48)
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    • Angew. Chem. Int. Ed. 2006, 45, 6544-6547;
    • (2006) Angew. Chem. Int. Ed , vol.45 , pp. 6544-6547
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    • Angew. Chem. Int. Ed. 2007, 46, 4320-4324.
    • (2007) Angew. Chem. Int. Ed , vol.46 , pp. 4320-4324
  • 26
    • 54749129590 scopus 로고    scopus 로고
    • Oxidation of small molecules: all reactions were performed with no additive or with 1-Fe or 1-Mn in a phosphate buffer solution (pH 7.4). a) Formaldehyde from DMSO (160 μM catalyst): DMSO (140 mM) was reacted with peroxynitrite (1.25 mM);
    • Oxidation of small molecules: all reactions were performed with no additive or with 1-Fe or 1-Mn in a phosphate buffer solution (pH 7.4). a) Formaldehyde from DMSO (160 μM catalyst): DMSO (140 mM) was reacted with peroxynitrite (1.25 mM);
  • 27
    • 54749157158 scopus 로고    scopus 로고
    • malondialdehyde from deoxyribose (1 μM catalyst): deoxyribose (10 mM) was reacted with peroxynitrite (390 μM);
    • b) malondialdehyde from deoxyribose (1 μM catalyst): deoxyribose (10 mM) was reacted with peroxynitrite (390 μM);
  • 28
    • 54749125522 scopus 로고    scopus 로고
    • nitration of fluorescein (5 μM catalyst): fluorescein (5 μM) was reacted with peroxynitrite (25 μM);
    • c) nitration of fluorescein (5 μM catalyst): fluorescein (5 μM) was reacted with peroxynitrite (25 μM);
  • 29
    • 54749111974 scopus 로고    scopus 로고
    • nitration of L-tyrosine (50 μM catalyst): L-tyrosine (80 μM) was reacted with peroxynitrite (220 μM);
    • d) nitration of L-tyrosine (50 μM catalyst): L-tyrosine (80 μM) was reacted with peroxynitrite (220 μM);
  • 30
    • 54749137466 scopus 로고    scopus 로고
    • 4 and phenanthroline (8 μM each) were added to DMSO (140 mM), followed by sodium ascorbate (500 μM) or glutathione (1 mM).
    • 4 and phenanthroline (8 μM each) were added to DMSO (140 mM), followed by sodium ascorbate (500 μM) or glutathione (1 mM).
  • 37
    • 54749100929 scopus 로고    scopus 로고
    • d of serum albumin-corrole conjugates (reference [10c]).
    • d of serum albumin-corrole conjugates (reference [10c]).
  • 39
    • 54749101651 scopus 로고    scopus 로고
    • 4 solution (5 μM) was added and the mixture was incubated at 378C. Oxidation was determined by measuring TBARS, conjugated dienes, and lipid peroxides by previously described methods (reference [23]).
    • 4 solution (5 μM) was added and the mixture was incubated at 378C. Oxidation was determined by measuring TBARS, conjugated dienes, and lipid peroxides by previously described methods (reference [23]).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.