Identification of novel small molecules that elevate Klotho expression

Biochemical Journal

Volumn 441, Issue 1, 2012, Pages 453-461

  King, Gwendalyn D ^a,d   Chen, CiDi ^a   Huang, Mickey M ^b   Zeldich, Ella ^a   Brazee, Patricia L ^a   Schuman, Eli R ^b   Robin, Maxime ^c   Cuny, Gregory D ^b   Glicksman, Marcie A ^b   Abraham, Carmela R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c AIX MARSEILLE UNIVERSITY   (France)

^d University of Alabama at Birmingham   (United States)

Author keywords

Choroid plexus; Fibroblast growth factor 23 (FGF23); High throughput screen; Kidney; Klotho; Longevity

Indexed keywords

FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CHOROID PLEXUS; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; INCUBATION TIME; KIDNEY; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RAT; SIGNAL TRANSDUCTION;

AGING; ANIMALS; CELL LINE; CLONING, MOLECULAR; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GLUCURONIDASE; KIDNEY; MICE; OPOSSUMS; RATS;

EID: 84055178054     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101909     Document Type: Article

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