-
1
-
-
2342599742
-
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression
-
Takeshita K, Fujimori T, Kurotaki Y et al. Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation 2004; 109: 1776-1782.
-
(2004)
Circulation
, vol.109
, pp. 1776-1782
-
-
Takeshita, K.1
Fujimori, T.2
Kurotaki, Y.3
-
2
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997; 390: 45-51.
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-O, M.1
Matsumura, Y.2
Aizawa, H.3
-
3
-
-
34250803923
-
Alpha-Klotho as a regulator of calcium homeostasis
-
Imura A, Tsuji Y, Murata M et al. alpha-Klotho as a regulator of calcium homeostasis. Science 2007; 316: 1615-1618.
-
(2007)
Science
, vol.316
, pp. 1615-1618
-
-
Imura, A.1
Tsuji, Y.2
Murata, M.3
-
4
-
-
27144440831
-
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
-
Chang Q, Hoefs S, van der Kemp AW et al. The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005; 310: 490-493.
-
(2005)
Science
, vol.310
, pp. 490-493
-
-
Chang, Q.1
Hoefs, S.2
Van Der Kemp, A.W.3
-
5
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 2006; 281: 6120-6123.
-
(2006)
J Biol Chem
, vol.281
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
-
6
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for FGF23
-
Urakawa I, Yamazaki Y, Shimada T et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006; 444: 770-774.
-
(2006)
Nature
, vol.444
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
-
7
-
-
13544270218
-
An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia
-
Benet-Pages A, Orlik P, Strom TM et al. An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. Hum Mol Genet 2005; 14: 385-390.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 385-390
-
-
Benet-Pages, A.1
Orlik, P.2
Strom, T.M.3
-
8
-
-
14344279878
-
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
-
Shimada T, Mizutani S, Muto T et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci USA 2001; 98: 6500-6505.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6500-6505
-
-
Shimada, T.1
Mizutani, S.2
Muto, T.3
-
9
-
-
0035186837
-
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
-
White KE, Carn G, Lorenz-Depiereux B et al. Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23. Kidney Int 2001; 60: 2079-2086.
-
(2001)
Kidney Int
, vol.60
, pp. 2079-2086
-
-
White, K.E.1
Carn, G.2
Lorenz-Depiereux, B.3
-
10
-
-
35848947037
-
Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells
-
Krajisnik T, Bjorklund P, Marsell R et al. Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells. J Endocrinol 2007; 195: 125-131.
-
(2007)
J Endocrinol
, vol.195
, pp. 125-131
-
-
Krajisnik, T.1
Bjorklund, P.2
Marsell, R.3
-
11
-
-
36849017126
-
The parathyroid is a target organ for FGF23 in rats
-
Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; 117: 4003-4008.
-
(2007)
J Clin Invest
, vol.117
, pp. 4003-4008
-
-
Ben-Dov, I.Z.1
Galitzer, H.2
Lavi-Moshayoff, V.3
-
12
-
-
16844379940
-
Pathogenesis of parathyroid hyperplasia in renal failure
-
Cozzolino M, Brancaccio D, Gallieni M et al. Pathogenesis of parathyroid hyperplasia in renal failure. J Nephrol 2005; 18: 5-8.
-
(2005)
J Nephrol
, vol.18
, pp. 5-8
-
-
Cozzolino, M.1
Brancaccio, D.2
Gallieni, M.3
-
13
-
-
35848930014
-
Regulation of fibroblast growth factor-23 in chronic kidney disease
-
Westerberg PA, Linde T, Wikstrom B et al. Regulation of fibroblast growth factor-23 in chronic kidney disease. Nephrol Dial Transplant 2007; 22: 3202-3207.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3202-3207
-
-
Westerberg, P.A.1
Linde, T.2
Wikstrom, B.3
-
14
-
-
27744545673
-
Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
-
Gutierrez O, Isakova T, Rhee E et al. Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol 2005; 16: 2205-2215.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2205-2215
-
-
Gutierrez, O.1
Isakova, T.2
Rhee, E.3
-
15
-
-
0034810211
-
Severely reduced production of klotho in human chronic renal failure kidney
-
Koh N, Fujimori T, Nishiguchi S et al. Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 2001; 280: 1015-1020.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1015-1020
-
-
Koh, N.1
Fujimori, T.2
Nishiguchi, S.3
-
16
-
-
53749105717
-
Type i membrane klotho expression is decreased and inversely correlated to serum calcium in primary hyperparathyroidism
-
Bjorklund P, Krajisnik T, Akerstrom G et al. Type I membrane klotho expression is decreased and inversely correlated to serum calcium in primary hyperparathyroidism. J Clin Endocrinol Metab 2008; 93: 4152-4157.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4152-4157
-
-
Bjorklund, P.1
Krajisnik, T.2
Akerstrom, G.3
-
17
-
-
73649099139
-
Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidism
-
Kumata C, Mizobuchi M, Ogata H et al. Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidism. Am J Nephrol 2010; 31: 230-238.
-
(2010)
Am J Nephrol
, vol.31
, pp. 230-238
-
-
Kumata, C.1
Mizobuchi, M.2
Ogata, H.3
-
18
-
-
74449086740
-
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
-
Komaba H, Goto S, Fujii H et al. Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients. Kidney Int 2010; 77: 232-238.
-
(2010)
Kidney Int
, vol.77
, pp. 232-238
-
-
Komaba, H.1
Goto, S.2
Fujii, H.3
-
19
-
-
74449094013
-
Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease
-
Galitzer H, Ben-Dov IZ, Silver J et al. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int 2010; 77: 211-218.
-
(2010)
Kidney Int
, vol.77
, pp. 211-218
-
-
Galitzer, H.1
Ben-Dov, I.Z.2
Silver, J.3
-
20
-
-
0034455926
-
Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism
-
Carling T, Rastad J, Szabo E et al. Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism. J Clin Endocrinol Metab 2000; 85: 2000-2003.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2000-2003
-
-
Carling, T.1
Rastad, J.2
Szabo, E.3
-
21
-
-
0031042732
-
Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism
-
Gogusev J, Duchambon P, Hory B et al. Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism. Kidney Int 1997; 51: 328-336.
-
(1997)
Kidney Int
, vol.51
, pp. 328-336
-
-
Gogusev, J.1
Duchambon, P.2
Hory, B.3
-
23
-
-
0035138842
-
Extracellular calcium sensing and extracellular calcium signaling
-
Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 2001; 81: 239-297.
-
(2001)
Physiol Rev
, vol.81
, pp. 239-297
-
-
Brown, E.M.1
MacLeod, R.J.2
-
24
-
-
0031892913
-
The nuclear vitamin D receptor: Biological and molecular regulatory properties revealed
-
Haussler MR, Whitfield GK, Haussler CA et al. The nuclear vitamin D receptor: biological and molecular regulatory properties revealed. J Bone Miner Res 1998; 13: 325-349.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 325-349
-
-
Haussler, M.R.1
Whitfield, G.K.2
Haussler, C.A.3
-
25
-
-
34548497123
-
Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study
-
Fliser D, Kollerits B, Neyer U et al. Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol 2007; 18: 2600-2608.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2600-2608
-
-
Fliser, D.1
Kollerits, B.2
Neyer, U.3
-
26
-
-
64949142537
-
Phosphate and the parathyroid
-
Silver J, Naveh-Many T. Phosphate and the parathyroid. Kidney Int 2009; 75: 898-905.
-
(2009)
Kidney Int
, vol.75
, pp. 898-905
-
-
Silver, J.1
Naveh-Many, T.2
-
27
-
-
0029887094
-
Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro
-
Slatopolsky E, Finch J, Denda M et al. Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro. J Clin Invest 1996; 97: 2534-2540.
-
(1996)
J Clin Invest
, vol.97
, pp. 2534-2540
-
-
Slatopolsky, E.1
Finch, J.2
Denda, M.3
-
28
-
-
0346849707
-
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
-
Tsujikawa H, Kurotaki Y, Fujimori T et al. Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol 2003; 17: 2393-2403.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2393-2403
-
-
Tsujikawa, H.1
Kurotaki, Y.2
Fujimori, T.3
-
29
-
-
33846922523
-
Potentiating effects of nonactive/active vitamin D analogues and ketoconazole in parathyroid cells
-
Segersten U, Bjorklund P, Hellman P et al. Potentiating effects of nonactive/active vitamin D analogues and ketoconazole in parathyroid cells. Clin Endocrinol (Oxf) 2007; 66: 399-404.
-
(2007)
Clin Endocrinol (Oxf)
, vol.66
, pp. 399-404
-
-
Segersten, U.1
Bjorklund, P.2
Hellman, P.3
-
30
-
-
18744371012
-
Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia
-
Yamazaki Y, Okazaki R, Shibata M et al. Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia. J Clin Endocrinol Metab 2002; 87: 4957-4960.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4957-4960
-
-
Yamazaki, Y.1
Okazaki, R.2
Shibata, M.3
-
31
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
32
-
-
33747120659
-
Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate
-
Levey AS, Coresh J, Greene T et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med 2006; 145: 247-254.
-
(2006)
Ann Intern Med
, vol.145
, pp. 247-254
-
-
Levey, A.S.1
Coresh, J.2
Greene, T.3
|