Functional variant of KLOTHO: A breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin

Oncogene

Volumn 29, Issue 1, 2010, Pages 26-33

  Wolf, I ^a,b   Laitman, Y ^a   Rubinek, T ^a   Abramovitz, L ^a   Novikov, I ^c   Beeri, R ^d   Kuro O, M ^e   Koeffler, H P ^f   Catane, R ^a,b   Freedman, L S ^c   Levy Lahad, E ^d   Karlan, B Y ^f   Friedman, E ^a,b   Kaufman, B ^a  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^d SHAARE ZEDEK MEDICAL CENTER   (Israel)

^e UNIVERSITY OF TEXAS AT DALLAS   (United States)

^f CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

BRCA; Breast cancer; Insulin growth factor 1; Klotho; Ovarian cancer; Tumor suppressor

Indexed keywords

BRCA1 PROTEIN; KLOTHO PROTEIN;

ADULT; ALLELE; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CANCER RISK; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; PROTEIN SECRETION;

ADULT; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC VARIATION; GENOTYPE; GLUCURONIDASE; HAPLOTYPES; HETEROZYGOTE; HUMANS; JEWS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; MUTATION; OVARIAN NEOPLASMS;

EID: 73849140439     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.301     Document Type: Article

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