메뉴 건너뛰기




Volumn 28, Issue 6, 2011, Pages 1089-1098

Osmotic regulation of bile acid transport, apoptosis and proliferation in rat liver

Author keywords

CD95; EGFR; Fyn; Integrins; Src

Indexed keywords

BILE ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; FAS ANTIGEN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 83755225852     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000335845     Document Type: Review
Times cited : (19)

References (103)
  • 1
    • 0031160517 scopus 로고    scopus 로고
    • Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver
    • Keppler D, König J: Hepatic canalicular membrane 5: Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver. FASEB J 1997;11:509-516. (Pubitemid 27274424)
    • (1997) FASEB Journal , vol.11 , Issue.7 , pp. 509-516
    • Keppler, D.1    Konig, J.2
  • 2
    • 0028960244 scopus 로고
    • ATP-dependent transport systems in the canalicular membrane of the hepatocyte
    • Gatmaitan ZC, Arias IM: ATP-dependent transport systems in the canalicular membrane of the hepatocyte. Physiol Rev 1995;75:261-275.
    • (1995) Physiol Rev , vol.75 , pp. 261-275
    • Gatmaitan, Z.C.1    Arias, I.M.2
  • 3
    • 0030753125 scopus 로고    scopus 로고
    • Molecular aspects of hepatobiliary transport
    • Müller M, Jansen PL: Molecular aspects of hepatobiliary transport. Am J Physiol 1997;272:1285-1303.
    • (1997) Am J Physiol , vol.272 , pp. 1285-1303
    • Müller, M.1    Jansen, P.L.2
  • 4
    • 0029615982 scopus 로고
    • Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile
    • Meier PJ: Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile. Am J Physiol 1995;269:801-812.
    • (1995) Am J Physiol , vol.269 , pp. 801-812
    • Meier, P.J.1
  • 6
    • 0027159022 scopus 로고
    • Involvement of microtubules in the swelling-induced stimulation of transcellular taurocholate transport in perfused rat liver
    • Häussinger D, Saha N, Hallbrucker C, Lang F, Gerok W: Involvement of microtubules in the swelling-induced stimulation of transcellular taurocholate transport in perfused rat liver. Biochem J 1993;291:355-360. (Pubitemid 23127013)
    • (1993) Biochemical Journal , vol.291 , Issue.2 , pp. 355-360
    • Haussinger, D.1    Saha, N.2    Hallbrucker, C.3    Lang, F.4    Gerok, W.5
  • 7
    • 0030048284 scopus 로고    scopus 로고
    • The role of cellular hydration in the regulation of cell function
    • Häussinger D: The role of cellular hydration in the regulation of cell function. Biochem J 1996;313:697-710. (Pubitemid 26050797)
    • (1996) Biochemical Journal , vol.313 , Issue.3 , pp. 697-710
    • Haussinger, D.1
  • 9
    • 2542466068 scopus 로고    scopus 로고
    • Molecular aspects of medicine: From experimental to clinical hepatology
    • DOI 10.1016/j.mam.2004.02.001, PII S0098299704000020
    • Häussinger D, Kubitz R, Reinehr R, Bode JG, Schliess F: Molecular aspects of medicine: from experimental to clinical hepatology. Mol Aspects Med 2004;25:221-360. (Pubitemid 38684174)
    • (2004) Molecular Aspects of Medicine , vol.25 , Issue.3 , pp. 221-360
    • Haussinger, D.1    Kubitz, R.2    Reinehr, R.3    Bode, J.G.4    Schliess, F.5
  • 10
    • 0028156367 scopus 로고
    • Regulation of cell function by the cellular hydration state
    • Häussinger D, Lang F, Gerok W: Regulation of cell function by the cellular hydration state. Am J Physiol 1994;267:343-355.
    • (1994) Am J Physiol , vol.267 , pp. 343-355
    • Häussinger, D.1    Lang, F.2    Gerok, W.3
  • 11
    • 35748953443 scopus 로고    scopus 로고
    • Osmoregulation of bile formation
    • Kubitz R, Häussinger D: Osmoregulation of bile formation. Methods Enzymol 2007;428:313-24.
    • (2007) Methods Enzymol , vol.428 , pp. 313-324
    • Kubitz, R.1    Häussinger, D.2
  • 12
    • 0030731742 scopus 로고    scopus 로고
    • Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane
    • DOI 10.1053/gast.1997.v113.pm9352844
    • Kubitz R, D'urso D, Keppler D, Häussinger D: Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane. Gastroenterology 1997;113:1438-42. (Pubitemid 27461228)
    • (1997) Gastroenterology , vol.113 , Issue.5 , pp. 1438-1442
    • Kubitz, R.1    D'Urso, D.2    Keppler, D.3    Haussinger, D.4
  • 14
    • 0035124048 scopus 로고    scopus 로고
    • Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity
    • DOI 10.1053/jhep.2001.22648
    • Schmitt M, Kubitz R, Lizun S, Wettstein M, Häussinger D: Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity. Hepatology 2001;33:509-18. (Pubitemid 32185211)
    • (2001) Hepatology , vol.33 , Issue.3 , pp. 509-518
    • Schmitt, M.1    Kubitz, R.2    Lizun, S.3    Wettstein, M.4    Haussinger, D.5
  • 15
    • 0034657167 scopus 로고    scopus 로고
    • Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide
    • DOI 10.1042/0264-6021:3480183
    • Dombrowski F, Kubitz R, Chittattu A, Wettstein M, Saha N, Häussinger D: Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide. Biochem J 2000;15:348:183-8. (Pubitemid 30312147)
    • (2000) Biochemical Journal , vol.348 , Issue.1 , pp. 183-188
    • Dombrowski, F.1    Kubitz, R.2    Chittattu, A.3    Wettstein, M.4    Saha, N.5    Haussinger, D.6
  • 16
    • 0029134069 scopus 로고
    • Metabolism of cysteinyl leukotrienes in the perfused rat liver: The influence of endotoxin pretreatment and the cellular hydration state
    • Wettstein M, Noé B, Häussinger D: Metabolism of cysteinyl leukotrienes in the perfused rat liver: the influence of endotoxin pretreatment and the cellular hydration state. Hepatology 1995;22:235-40.
    • (1995) Hepatology , vol.22 , pp. 235-240
    • Wettstein, M.1    Noé, B.2    Häussinger, D.3
  • 17
    • 0033564937 scopus 로고    scopus 로고
    • Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes
    • DOI 10.1042/0264-6021:3400585
    • Kubitz R, Warskulat U, Schmitt M, Häussinger D: Dexamethasone-and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes. Biochem J 1999;340:585-91. (Pubitemid 29312854)
    • (1999) Biochemical Journal , vol.340 , Issue.3 , pp. 585-591
    • Kubitz, R.1    Warskulat, U.2    Schmitt, M.3    Haussinger, D.4
  • 18
    • 0032738402 scopus 로고    scopus 로고
    • Regulation of bile salt export pump mRNA levels by dexamethasone and osmolarity in cultured rat hepatocytes
    • Warskulat U, Kubitz R, Wettstein M, Stieger B, Meier PJ, Häussinger D: Regulation of bile salt export pump mRNA levels by dexamethasone and osmolarity in cultured rat hepatocytes. Biol Chem 1999;380:1273-9.
    • (1999) Biol Chem , vol.380 , pp. 1273-1279
    • Warskulat, U.1    Kubitz, R.2    Wettstein, M.3    Stieger, B.4    Meier, P.J.5    Häussinger, D.6
  • 19
    • 3042594002 scopus 로고    scopus 로고
    • Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis
    • DOI 10.1016/S0016-5085(03)00274-9
    • Häussinger D, Kurz AK, Wettstein M, Graf D, vom Dahl S, Schliess F: Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis. Gastroenterology 2003;124:1476-1487. (Pubitemid 36531820)
    • (2003) Gastroenterology , vol.124 , Issue.5 , pp. 1476-1487
    • Haussinger, D.1    Kordelia Kurz, A.2    Wettstein, M.3    Graf, D.4    Vom Dahl, S.5    Schliess, F.6
  • 21
    • 2442674271 scopus 로고    scopus 로고
    • Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver
    • DOI 10.1074/jbc.M313901200
    • Schliess F, Reissmann R, Reinehr R, vom Dahl S, Häussinger D: Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver. J Biol Chem 2004;279:21294-21301. (Pubitemid 38656536)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.20 , pp. 21294-21301
    • Schliess, F.1    Reissmann, R.2    Reinehr, R.3    Vom Dahl, S.4    Haussinger, D.5
  • 22
    • 0031151945 scopus 로고    scopus 로고
    • Integrins, tensegrity, and mechanotransduction
    • Ingber DE: Integrins, tensegrity, and mechanotransduction. Gravit Space Biol Bull 1997;10:49-55.
    • (1997) Gravit Space Biol Bull , vol.10 , pp. 49-55
    • Ingber, D.E.1
  • 23
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • DOI 10.1016/S0092-8674(02)00971-6
    • Hynes RO: Integrins: bidirectional, allosteric signaling machines. Cell 2002;110:673-87. (Pubitemid 35283958)
    • (2002) Cell , vol.110 , Issue.6 , pp. 673-687
    • Hynes, R.O.1
  • 24
    • 0031745571 scopus 로고    scopus 로고
    • Signal transduction and signal modulation by cell adhesion receptors: The role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins
    • Aplin AE, Howe A, Alahari SK, Juliano RL: Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev 1998;50:197-263. (Pubitemid 28304026)
    • (1998) Pharmacological Reviews , vol.50 , Issue.2 , pp. 197-263
    • Aplin, A.E.1    Howe, A.2    Alahari, S.K.3    Juliano, R.L.4
  • 25
    • 0036222549 scopus 로고    scopus 로고
    • Sensing the environment: A historical perspective on integrin signal transduction
    • DOI 10.1038/ncb0402-e83
    • Miranti CK, Brugge JS: Sensing the environment: A historical perspective on integrin signal transduction. Nat Cell Biol. 2002;4:E83-90. (Pubitemid 34308848)
    • (2002) Nature Cell Biology , vol.4 , Issue.4
    • Miranti, C.K.1    Brugge, J.S.2
  • 26
    • 0034743453 scopus 로고    scopus 로고
    • The integrin, alpha61, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells
    • DOI 10.1053/jhep.2001.25224
    • Carloni V, Mazzocca A, Pantaleo P, Cordella C, Laffi G, Gentilini P: The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells. Hepatology 2001;34:42-9. (Pubitemid 32591481)
    • (2001) Hepatology , vol.34 , Issue.1 , pp. 42-49
    • Carloni, V.1    Mazzocca, A.2    Pantaleo, P.3    Cordella, C.4    Laffi, G.5    Gentilini, P.6
  • 27
    • 0035954232 scopus 로고    scopus 로고
    • Proteolysis of integrin alpha5 and beta1 subunits involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells
    • Hsu SL, Cheng CC, Shi YR, Chiang CW: Proteolysis of integrin alpha5 and beta1 subunits involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. Cancer Lett 2001;167:193-204.
    • (2001) Cancer Lett , vol.167 , pp. 193-204
    • Hsu, S.L.1    Cheng, C.C.2    Shi, Y.R.3    Chiang, C.W.4
  • 29
    • 0030031467 scopus 로고    scopus 로고
    • Regulation of taurocholate excretion by a hypo-osmolarity-activated signal transduction pathway in rat liver
    • DOI 10.1053/gast.1996.v110.pm8608896
    • Noe B, Schliess F, Wettstein M, Heinrich S, Häussinger D: Regulation of taurocholate excretion by a hypoosmolarity-activated signal transduction pathway in rat liver. Gastroenterology 1996;110:858-865. (Pubitemid 26071853)
    • (1996) Gastroenterology , vol.110 , Issue.3 , pp. 858-865
    • Noe, B.1    Schliess, F.2    Wettstein, M.3    Heinrich, S.4    Haussinger, D.5
  • 30
    • 0034910937 scopus 로고    scopus 로고
    • MAPK activation and translocation of the bile salt export pump in rats
    • Kurz AK, Graf D, Schmitt M, vom Dahl S, Häussinger D: Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats. Gastroenterology 2001;121:407-19. (Pubitemid 32729388)
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 407-419
    • Kurz, A.K.1    Graf, D.2    Schmitt, M.3    Vom Dahl, S.4    HaUssinger, D.5
  • 31
    • 0029775681 scopus 로고    scopus 로고
    • RGD and other recognition sequences for integrins
    • DOI 10.1146/annurev.cellbio.12.1.697
    • Ruoslahti E: RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 1996;12:697-715. (Pubitemid 26422728)
    • (1996) Annual Review of Cell and Developmental Biology , vol.12 , pp. 697-715
    • Ruoslahti, E.1
  • 34
    • 33747357530 scopus 로고    scopus 로고
    • Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarityinduced hepatocyte apoptosis
    • Reinehr R, Becker S, Braun J, Eberle A, Grether-Beck S, Häussinger D: Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarityinduced hepatocyte apoptosis. J Biol Chem 2006;281:23150-23166.
    • (2006) J Biol Chem , vol.281 , pp. 23150-23166
    • Reinehr, R.1    Becker, S.2    Braun, J.3    Eberle, A.4    Grether-Beck, S.5    Häussinger, D.6
  • 35
    • 0027502926 scopus 로고
    • + channel activation, cell volume changes and eicosanoid formation
    • DOI 10.1111/j.1432-1033.1993.tb17570.x
    • Hallbrucker C, Ritter M, Lang F, Gerok W, Häussinger D: Hydroperoxide metabolism in rat liver: K+ channel activation, cell volume changes and eicosanoid formation. Eur J Biochem 1993;211:449-458. (Pubitemid 23050014)
    • (1993) European Journal of Biochemistry , vol.211 , Issue.3 , pp. 449-458
    • Hallbrucker, C.1    Ritter, M.2    Lang, F.3    Gerok, W.4    Haussinger, D.5
  • 37
    • 0037389392 scopus 로고    scopus 로고
    • Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation
    • Reinehr R, Schliess F, Häussinger D: Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation. FASEB J 2003;17:731-733.
    • (2003) FASEB J , vol.17 , pp. 731-733
    • Reinehr, R.1    Schliess, F.2    Häussinger, D.3
  • 38
    • 0033947842 scopus 로고    scopus 로고
    • Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-Butyl hydroperoxide and chloro-dinitrobenzene
    • Schmitt M, Kubitz R, Wettstein M, vom Dahl S, Häussinger D: Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tertbutyl hydroperoxide and chlorodinitrobenzene. Biol Chem 2000;381:487-95. (Pubitemid 30453827)
    • (2000) Biological Chemistry , vol.381 , Issue.5-6 , pp. 487-495
    • Schmitt, M.1    Kubitz, R.2    Wettstein, M.3    Vom Dahl, S.4    Haussinger, D.5
  • 39
    • 28844489800 scopus 로고    scopus 로고
    • Bile salt-induced apoptosis involves NADPH oxidase isoform activation
    • DOI 10.1053/j.gastro.2005.09.023, PII S0016508505018494
    • Reinehr R, Becker S, Keitel V, Eberle A, Grether-Beck S, Häussinger D: Bile saltinduced apoptosis involves NADPH oxidase isoform activation and hepatocyte shrinkage. Gastroenterology 2005;129:2009-2031. (Pubitemid 41772977)
    • (2005) Gastroenterology , vol.129 , Issue.6 , pp. 2009-2031
    • Reinehr, R.1    Becker, S.2    Keitel, V.3    Eberle, A.4    Grether-Beck, S.5    Haussinger, D.6
  • 41
    • 2642584894 scopus 로고    scopus 로고
    • The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95
    • DOI 10.1074/jbc.M401519200
    • Reinehr R, Becker S, Hängen A, Häussinger D: The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95. J Biol Chem 2004;279:23977-87. Epub 2004 Mar 23. Erratum in: J Biol Chem 2004;279:31990. (Pubitemid 38725256)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.23 , pp. 23977-23987
    • Reinehr, R.1    Becker, S.2    Hongen, A.3    Haussinger, D.4
  • 42
    • 83755203890 scopus 로고    scopus 로고
    • The Src-family kinase Fyn mediates hyperosmolarityinduced Mrp2-and Bsep-retrieval from the canalicular membrane
    • doi/10.1074/jbc.M111.292896
    • Cantore M, Reinehr R, Sommerfeld A, Becker M, Häussinger D: The Src-family kinase Fyn mediates hyperosmolarityinduced Mrp2-and Bsep-retrieval from the canalicular membrane. J Biol Chem 2011;doi/10.1074/jbc.M111.292896.
    • (2011) J Biol Chem
    • Cantore, M.1    Reinehr, R.2    Sommerfeld, A.3    Becker, M.4    Häussinger, D.5
  • 43
    • 0039180006 scopus 로고    scopus 로고
    • Cell shrinkage regulates Src kinases and induces tyrosine phosphorylation of cortactin, independent of the osmotic regulation of Na+/H+ exchangers
    • Kapus A, Szászi K, Sun J, Rizoli S, Rotstein OD: Cell shrinkage regulates Src kinases and induces tyrosine phosphorylation of cortactin, independent of the osmotic regulation of Na+/H+ exchangers. J Biol Chem 1999;274:8093-102.
    • (1999) J Biol Chem , vol.274 , pp. 8093-8102
    • Kapus, A.1    Szászi, K.2    Sun, J.3    Rizoli, S.4    Rotstein, O.D.5
  • 44
    • 0030971098 scopus 로고    scopus 로고
    • Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation
    • DOI 10.1074/jbc.272.21.13911
    • Huang C, Ni Y, Wang T, Gao Y, Haudenschild CC, Zhan X: Downregulation of the filamentous actin crosslinking activity of cortactin by Srcmediated tyrosine phosphorylation. J Biol Chem 1997;272:13911-5. (Pubitemid 27224834)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.21 , pp. 13911-13915
    • Huang, C.1    Ni, Y.2    Wang, T.3    Gao, Y.4    Haudenschild, C.C.5    Zhan, X.6
  • 45
    • 33749431556 scopus 로고    scopus 로고
    • Cortactin: The gray eminence of the cytoskeleton
    • DOI 10.1152/physiol.00012.2006
    • Cosen-Binker LI, Kapus A: Cortactin: the gray eminence of the cytoskeleton. Physiology (Bethesda) 2006;21:352-61. (Pubitemid 44511763)
    • (2006) Physiology , vol.21 , Issue.5 , pp. 352-361
    • Cosen-Binker, L.I.1    Kapus, A.2
  • 46
    • 0016379549 scopus 로고
    • An electronmicroscope study of cell deletion in the anuran tadpole tail during spontaneous metamorphosis with special reference to apoptosis of striated muscle fibers
    • Kerr JF, Harmon B, Searle J: An electronmicroscope study of cell deletion in the anuran tadpole tail during spontaneous metamorphosis with special reference to apoptosis of striated muscle fibers. J Cell Science 1974;14:571-585.
    • (1974) J Cell Science , vol.14 , pp. 571-585
    • Kerr, J.F.1    Harmon, B.2    Searle, J.3
  • 48
    • 33847036909 scopus 로고    scopus 로고
    • Flow cytometric analysis of cell shrinkage and monovalent ions during apoptosis
    • Bortner CD, Cidlowski JA: Flow cytometric analysis of cell shrinkage and monovalent ions during apoptosis. Methods Cell Biol 2001;66:49-67.
    • (2001) Methods Cell Biol , vol.66 , pp. 49-67
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 49
    • 0036948067 scopus 로고    scopus 로고
    • Apoptotic volume decrease and the incredible shrinking cell
    • DOI 10.1038/sj.cdd.4401126
    • Bortner CD, Cidlowski JA: Apoptotic volume decrease and the incredible shrinking cell. Cell Death Diff 2002;9:1307-1310. (Pubitemid 36097700)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.12 , pp. 1307-1310
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 51
    • 0034130812 scopus 로고    scopus 로고
    • + -ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis
    • DOI 10.1023/A:1009684713784
    • Nobel CS, Aronson JK, van den Dobbelsteen DJ, Slater AF: Inhibition of Na+/K+-ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis. Apoptosis 2000;5:153-163. (Pubitemid 30399389)
    • (2000) Apoptosis , vol.5 , Issue.2 , pp. 153-163
    • Nobel, C.S.I.1    Aronson, J.K.2    Van Den Dobbelsteen, D.J.3    Slater, A.F.G.4
  • 52
    • 0032568602 scopus 로고    scopus 로고
    • Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes
    • Szabo I, Lepple-Wienhues A, Kaba KN, Zoratti M, Gulbins E, Lang F: Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes. Proc Natl Acad Sci USA 1998;95:6169-6174.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6169-6174
    • Szabo, I.1    Lepple-Wienhues, A.2    Kaba, K.N.3    Zoratti, M.4    Gulbins, E.5    Lang, F.6
  • 55
    • 0035310427 scopus 로고    scopus 로고
    • Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)
    • DOI 10.1111/j.1469-7793.2001.0003g.x
    • Okada Y, Maeno E, Shimizu T, Dezaki K, Wang J, Morishima S: Receptormediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol 2001;532:3-16. (Pubitemid 32303268)
    • (2001) Journal of Physiology , vol.532 , Issue.1 , pp. 3-16
    • Okada, Y.1    Maeno, E.2    Shimizu, T.3    Dezaki, K.4    Wang, J.5    Morishima, S.6
  • 56
    • 18344401788 scopus 로고    scopus 로고
    • + and cell shrinkage. A role for PKC upstream of caspases
    • DOI 10.1074/jbc.M909563199
    • Gomez-Angelats M, Bortner CD, Cidlowski JA: Protein kinase C (PKC) inhibits fas receptor-induced apoptosis through modulation of the loss of K+ and cell shrinkage. A role for PKC upstream of caspases. J Biol Chem 2000;275:19609-19619. (Pubitemid 30441555)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.26 , pp. 19609-19619
    • Gomez-Angelats, M.1    Bortner, C.D.2    Cidlowski, J.A.3
  • 57
    • 0035397708 scopus 로고    scopus 로고
    • + ] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release
    • DOI 10.1042/0264-6021:3570137
    • Thompson GJ, Langlais C, Cain K, Conley EC, Cohen GM: Elevated extracellular K+ inhibits death-receptorand chemical-mediated apoptosis prior to caspase activation and cytochrome c release. Biochem J 2001;357:137-145. (Pubitemid 32642911)
    • (2001) Biochemical Journal , vol.357 , Issue.1 , pp. 137-145
    • Thompson, G.J.1    Langlais, C.2    Cain, K.3    Conley, E.C.4    Cohen, G.M.5
  • 59
    • 0029823496 scopus 로고    scopus 로고
    • Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes
    • Bortner CD, Cidlowski JA: Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes. Am J Physiol 1996;40:C950-C961.
    • (1996) Am J Physiol , vol.40
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 60
    • 0037389392 scopus 로고    scopus 로고
    • Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation
    • Reinehr R, Schliess F, Häussinger D: Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation. FASEB J 2003;17:731-733.
    • (2003) FASEB J , vol.17 , pp. 731-733
    • Reinehr, R.1    Schliess, F.2    Häussinger, D.3
  • 61
    • 0036727296 scopus 로고    scopus 로고
    • Hyperosmolarity triggers CD95 membrane trafficking and sensitizes rat hepatocytes toward CD95L-induced apoptosis
    • DOI 10.1053/jhep.2002.35447
    • Reinehr R, Fischer R, Graf D, Schliess F, Häussinger D: Hyperosmolarity triggers CD95 membrane trafficking and sensitizes rat hepatocytes towards CD95 ligand-induced apoptosis. Hepatology 2002;36:602-614. (Pubitemid 34977170)
    • (2002) Hepatology , vol.36 , Issue.3 , pp. 602-614
    • Reinehr, R.1    Graf, D.2    Fischer, R.3    Schliess, F.4    Haussinger, D.5
  • 62
    • 0041322990 scopus 로고    scopus 로고
    • Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation
    • DOI 10.1016/S0016-5085(03)01055-2
    • Reinehr R, Graf D, Häussinger D: Bilesalt-induced apoptosis involves epidermal growth factor receptor-dependent tyrosine phosphorylation of CD95 in rat hepatocytes. Gastroenterology 2003;125:839-853. (Pubitemid 37070701)
    • (2003) Gastroenterology , vol.125 , Issue.3 , pp. 839-853
    • Reinehr, R.1    Graf, D.2    Haussinger, D.3
  • 63
    • 0347361545 scopus 로고    scopus 로고
    • Inhibition of Bile Salt-Induced Apoptosis by Cyclic AMP Involves Serine/Threonine Phosphorylation of CD95
    • DOI 10.1053/j.gastro.2003.09.044
    • Reinehr R, Häussinger D: Inhibition of apoptosis by cyclic AMP involves protein kinase A-dependent serine/threonine phosphorylation of CD95. Gastroenterology 2004;126:249-262. (Pubitemid 38040740)
    • (2004) Gastroenterology , vol.126 , Issue.SUPPL. 11 , pp. 249-262
    • Reinehr, R.1    Haussinger, D.2
  • 64
    • 12844269205 scopus 로고    scopus 로고
    • Fluorescence resonace energy transfer analysis of proapoptotic CD95-EGF receptor interactions in Huh7 cells
    • DOI 10.1002/hep.20564
    • Eberle A, Reinehr R, Becker S, Häussinger D: Fluorescence resonance energy transfer analysis of proapoptotic CD95-EGF receptor interactions in Huh7 cells. Hepatology 2005;41:315-326. (Pubitemid 40165375)
    • (2005) Hepatology , vol.41 , Issue.2 , pp. 315-326
    • Eberle, A.1    Reinehr, R.2    Becker, S.3    Haussinger, D.4
  • 65
    • 22844440003 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis
    • DOI 10.1074/jbc.M414361200
    • Reinehr R, Becker S, Eberle A, Grether-Beck S, Häussinger D: Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis. J Biol Chem 2005;280:27179-27194. (Pubitemid 41040757)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.29 , pp. 27179-27194
    • Reinehr, R.1    Becker, S.2    Eberle, A.3    Grether-Beck, S.4    Haussinger, D.5
  • 66
    • 33846595768 scopus 로고    scopus 로고
    • Hydrophobic bile salts trigger ceramide formation through endosomal acidification
    • DOI 10.1515/BC.2007.021
    • Becker S, Reinehr R, Grether-Beck S, Eberle A, Häussinger D: Hydrophobic bile salts trigger ceramide formation through endosomal acidification. Biol Chem 2006;388:185-196. (Pubitemid 46184148)
    • (2007) Biological Chemistry , vol.388 , Issue.2 , pp. 185-196
    • Becker, S.1    Reinehr, R.2    Grether-Beck, S.3    Eberle, A.4    Haussinger, D.5
  • 67
    • 0036253433 scopus 로고    scopus 로고
    • The cellular hydration state: A critical determinant for cell death and survival
    • DOI 10.1515/BC.2002.059
    • Schliess F, Häussinger D: The cellular hydration state: A critical determinant for cell death and survival. Biol Chem 2002;383:577-583. (Pubitemid 34506294)
    • (2002) Biological Chemistry , vol.383 , Issue.3-4 , pp. 577-583
    • Schliess, F.1    Haussinger, D.2
  • 68
    • 0036134932 scopus 로고    scopus 로고
    • Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases
    • DOI 10.1097/00062752-200201000-00003
    • Lambeth JD: Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases. Curr Opin Hematol 2002;9:11-17. (Pubitemid 34025306)
    • (2002) Current Opinion in Hematology , vol.9 , Issue.1 , pp. 11-17
    • Lambeth, J.D.1
  • 69
    • 0032211769 scopus 로고    scopus 로고
    • Signal transduction of stress via ceramide
    • Mathias S, Pena LA, Kolesnick RN: Signal transduction of stress via ceramide. Biochem J 1998;335:465-480. (Pubitemid 28515396)
    • (1998) Biochemical Journal , vol.335 , Issue.3 , pp. 465-480
    • Mathias, S.1    Pena, L.A.2    Kolesnick, R.N.3
  • 70
    • 0025355772 scopus 로고
    • Volume regulation in liver: Further characterization by inhibitors and ionic substitutions
    • Häussinger D, Stehle T, Lang F: Volume regulation in liver: further characterization by inhibitors and ionic substitutions. Hepatology 1990;11:243-254. (Pubitemid 20101472)
    • (1990) Hepatology , vol.11 , Issue.2 , pp. 243-254
    • Haussinger, D.1    Stehle, T.2    Lang, F.3
  • 72
    • 0029924518 scopus 로고    scopus 로고
    • Ion transport in hepatocytes: Mechanisms and correlations to cell volume, hormone actions and metabolism
    • Graf J, Häussinger D: Ion transport in hepatocytes: mechanisms and correlations to cell volume, hormone actions and metabolism. J. Hepatol 1996;24:53-77. (Pubitemid 26090188)
    • (1996) Journal of Hepatology, Supplement , vol.24 , Issue.1 , pp. 53-77
    • Graf, J.1    Haussinger, D.2
  • 73
    • 0019249610 scopus 로고
    • Evidence for direct coupling of proton and anion transport in chromaffin granules
    • Pazoles CJ, Creutz CE, Pollard HB: Evidence for direct coupling of proton and anion transport in chromaffin granules. Ann N Y Acad Sci 1980;358:354-355.
    • (1980) Ann N y Acad Sci , vol.358 , pp. 354-355
    • Pazoles, C.J.1    Creutz, C.E.2    Pollard, H.B.3
  • 74
    • 0023645189 scopus 로고
    • The purified ATPase from chromaffin granule membranes is an anion-dependent proton pump
    • Moriyama Y, Nelson N: The purified ATPase from chromaffin granule membranes is an anion-dependent proton pump. J Biol Chem 1987;262:9175-9180.
    • (1987) J Biol Chem , vol.262 , pp. 9175-9180
    • Moriyama, Y.1    Nelson, N.2
  • 75
    • 0026643103 scopus 로고
    • Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes
    • Zeuzem S, Feick P, Zimmermann P, Haase W, Kahn RA, Schulz I: Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes. Proc Natl Acad Sci USA 1992;89:6619-23.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6619-6623
    • Zeuzem, S.1    Feick, P.2    Zimmermann, P.3    Haase, W.4    Kahn, R.A.5    Schulz, I.6
  • 77
    • 0037201939 scopus 로고    scopus 로고
    • Sphingomyelinases: Enzymology and membrane activity
    • DOI 10.1016/S0014-5793(02)03482-8, PII S0014579302034828
    • Goni FM, Alonso A: Sphingomyelinases: enzymology and membrane activity. FEBS Lett 2002;531:38-46. (Pubitemid 35232782)
    • (2002) FEBS Letters , vol.531 , Issue.1 , pp. 38-46
    • Goi, F.M.1    Alonso, A.2
  • 78
    • 0022367017 scopus 로고
    • Reduction of acid sphingomyelinase activity in human fibroblasts induced by AY-9944 and other cationic amphiphilic drugs
    • Yoshida Y, Arimoto K, Sato M, Sakuragawa N, Arima M, Satoyoshi E: Reduction of acid sphingomyelinase activity in human fibroblasts induced by AY-9944 and other cationic amphiphilic drugs. J Biochem 1985;98:1669-1679. (Pubitemid 16169203)
    • (1985) Journal of Biochemistry , vol.98 , Issue.6 , pp. 1669-1679
    • Yoshida, Y.1    Arimoto, K.2    Sato, M.3
  • 79
    • 2342570273 scopus 로고    scopus 로고
    • Acid and neutral sphingomyelinases: Roles and mechanisms of regulation
    • DOI 10.1139/o03-091
    • Marchesini N, Hannun YA: Acid and neutral sphingomyelinases: roles and mechanisms of regulation. Biochem Cell Biol 2004;82:27-44. (Pubitemid 38580872)
    • (2004) Biochemistry and Cell Biology , vol.82 , Issue.1 , pp. 27-44
    • Marchesini, N.1    Hannun, Y.A.2
  • 80
    • 0021055866 scopus 로고
    • The active site of lysosomal sphingomyelinase: Evidence for the involvement of hydrophobic and ionic groups
    • Callahan JW, Jones CS, Davidson DJ, Shankaran P: The active site of lysosomal sphingomyelinase: evidence for the involvement of hydrophobic and ionic groups. J Neurosci Res 1983;10:151-163. (Pubitemid 14231903)
    • (1983) Journal of Neuroscience Research , vol.10 , Issue.2 , pp. 151-163
    • Callahan, J.W.1    Jones, C.S.2    Davidson, D.J.3    Shankaran, P.4
  • 81
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily
    • Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Herwig Ponstinglll, Peter H, Krammer S: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. J Biol Chem 1992;267:10709-10715.
    • (1992) J Biol Chem , vol.267 , pp. 10709-10715
    • Oehm, A.1    Behrmann, I.2    Falk, W.3    Pawlita, M.4    Maier, G.5    Klas, C.6    Ponstinglll, H.7    Peter, H.8    Krammer, S.9
  • 82
    • 38349132722 scopus 로고    scopus 로고
    • Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes
    • Reinehr R, Sommerfeld A, Keitel V, Grether-Beck S, Häussinger D: Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes. J Biol Chem 2008;283:2211-2222.
    • (2008) J Biol Chem , vol.283 , pp. 2211-2222
    • Reinehr, R.1    Sommerfeld, A.2    Keitel, V.3    Grether-Beck, S.4    Häussinger, D.5
  • 83
    • 0031972578 scopus 로고    scopus 로고
    • Regulation of CD95 (APO-1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells
    • DOI 10.1002/hep.510270131
    • Müschen M, Warskulat U, Douillard P, Gilbert E, Häussinger D: Regulation of CD95 (APO-1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells. Hepatology 1998;27:200-208. (Pubitemid 28041555)
    • (1998) Hepatology , vol.27 , Issue.1 , pp. 200-208
    • Muschen, M.1    Warskulat, U.2    Douillard, P.3    Gilbert, E.4    Hussinger, D.5
  • 84
    • 0032971766 scopus 로고    scopus 로고
    • Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation
    • Müschen M, Warskulat U, Peters-Regehr T, Bode JG, Kubitz R, Häussinger D: Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation. Gastroenterology 1999;116:666-677. (Pubitemid 29106775)
    • (1999) Gastroenterology , vol.116 , Issue.3 , pp. 666-677
    • Muschen, M.1    Warskulat, U.2    Peters-Regehr, T.3    Bode, J.G.4    Kubitz, R.5    Haussinger, D.6
  • 85
    • 17344370605 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate-mediated protection against bile acid- induced apoptosis in cultured rat hepatocytes
    • DOI 10.1002/hep.510270519
    • Webster CR, Anwer MS: Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes. Hepatology 1998;27:1324-1331. (Pubitemid 28227860)
    • (1998) Hepatology , vol.27 , Issue.5 , pp. 1324-1331
    • Webster, C.R.L.1    Sawkat Anwer, M.2
  • 86
    • 1642409200 scopus 로고    scopus 로고
    • CD95-tyrosine Nitration Inhibits Hyperosmotic and CD95 Ligand-induced CD95 Activation in Rat Hepatocytes
    • DOI 10.1074/jbc.M311997200
    • Reinehr R, Gärg B, Hängen A, Häussinger D: CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes. J Biol Chem 2004;279:10364-10373. (Pubitemid 38372644)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.11 , pp. 10364-10373
    • Reinehr, R.1    Gorg, B.2    Hongen, A.3    Haussinger, D.4
  • 87
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • DOI 10.1038/ni1001-907
    • Bogdan C: Nitric oxide and the immune response. Nat Immunol 2001;2:907-916. (Pubitemid 32976162)
    • (2001) Nature Immunology , vol.2 , Issue.10 , pp. 907-916
    • Bogdan, C.1
  • 88
    • 77956213410 scopus 로고    scopus 로고
    • Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver
    • Reinehr R, Sommerfeld A, Häussinger D: Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver. J Biol Chem 2010;285:25904-25912.
    • (2010) J Biol Chem , vol.285 , pp. 25904-25912
    • Reinehr, R.1    Sommerfeld, A.2    Häussinger, D.3
  • 89
    • 0030077331 scopus 로고    scopus 로고
    • Regulation of signal transduction during liver regeneration
    • Diehl AM, Rai RM: Liver regeneration 3: Regulation of signal transduction during liver regeneration. FASEB J 1996;10:215-227. (Pubitemid 26079941)
    • (1996) FASEB Journal , vol.10 , Issue.2 , pp. 215-227
    • Diehl, A.M.1    Rai, R.M.2
  • 90
    • 0032577051 scopus 로고    scopus 로고
    • The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: Its role in cell growth and disease
    • DOI 10.1098/rstb.1998.0228
    • Hunter T: The phosphorylation of proteins on tyrosine: its role in cell growth and disease. Philos Trans R Soc Lond B Biol Sci 1998;353:583-605. (Pubitemid 28314105)
    • (1998) Philosophical Transactions of the Royal Society B: Biological Sciences , vol.353 , Issue.1368 , pp. 583-605
    • Hunter, T.1
  • 91
    • 0031919552 scopus 로고    scopus 로고
    • Insulin signal transduction through protein kinase cascades
    • DOI 10.1023/A:1006823109415
    • Avruch J: Insulin signal transduction through protein kinase cascades. Mol Cell Biochem 1998;182:31-48. (Pubitemid 28181646)
    • (1998) Molecular and Cellular Biochemistry , vol.182 , Issue.1-2 , pp. 31-48
    • Avruch, J.1
  • 92
    • 0032987220 scopus 로고    scopus 로고
    • Insulin signalling: Metabolic pathways and mechanisms for specificity
    • DOI 10.1016/S0898-6568(99)00025-X, PII S089865689900025X
    • Nystrom FH, Quon MJ: Insulin signalling: metabolic pathways and mechanisms for specificity. Cell Signal 1999;11:563-574. (Pubitemid 29255888)
    • (1999) Cellular Signalling , vol.11 , Issue.8 , pp. 563-574
    • Nystrom, F.H.1    Quon, M.2
  • 93
    • 0032898857 scopus 로고    scopus 로고
    • The insulin signaling pathway
    • DOI 10.1007/PL00005896
    • Taha C; Klip A: The insulin signaling pathway. J Membr Biol 1999;169:1-12. (Pubitemid 29211069)
    • (1999) Journal of Membrane Biology , vol.169 , Issue.1 , pp. 1-12
    • Taha, C.1    Klip, A.2
  • 94
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signalling system and the IRS proteins
    • White MF: The insulin signalling system and the IRS proteins. Diabetologia 1997;40;2-17.
    • (1997) Diabetologia , vol.40 , pp. 2-17
    • White, M.F.1
  • 95
    • 0042570843 scopus 로고    scopus 로고
    • Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
    • Virkamaki A, Ueki K, Kahn CR: Proteinprotein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 1999;103:931-943. (Pubitemid 29169600)
    • (1999) Journal of Clinical Investigation , vol.103 , Issue.7 , pp. 931-943
    • Virkamaki, A.1    Ueki, K.2    Kahn, C.R.3
  • 96
    • 0036183603 scopus 로고    scopus 로고
    • Coordinated action of protein tyrosine phosphatases in insulin signal transduction
    • DOI 10.1046/j.0014-2956.2002.02756.x
    • Cheng A, Dube N, Gu F, Tremblay ML: Coordinated action of protein tyrosine phosphatases in insulin signal transduction. Eur J Biochem 2002;269:1050-1059. (Pubitemid 34175362)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.4 , pp. 1050-1059
    • Cheng, A.1    Dube, N.2    Gu, F.3    Tremblay, M.L.4
  • 97
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • DOI 10.1038/nrm1837, PII NRM1837
    • Taniguchi CM, Emanuelli B, Kahn CR: Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 2006;7:85-96. (Pubitemid 43278292)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 98
    • 33750374137 scopus 로고    scopus 로고
    • The twentieth century struggle to decipher insulin signalling
    • DOI 10.1038/nrm2043, PII NRM2043
    • Cohen P: The twentieth century struggle to decipher insulin signalling. Nat Rev Mol Cell Biol 2006;7:867-873. (Pubitemid 44627480)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.11 , pp. 867-873
    • Cohen, P.1
  • 101
    • 0029557319 scopus 로고
    • Role of growth factors and cytokines in hepatic regeneration
    • Fausto N, Laird AD, Webber EM: Role of growth factors and cytokines in hepatic regeneration. FASEB J 1995;9:1527-1536.
    • (1995) FASEB J , vol.9 , pp. 1527-1536
    • Fausto, N.1    Laird, A.D.2    Webber, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.