Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

Current Opinion in Hematology

Volumn 9, Issue 1, 2002, Pages 11-17

  Lambeth, J D ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN DUOX; PROTEIN NOX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; BIOLOGY; CELL HYPOXIA; CELL RESPIRATION; ENZYME METABOLISM; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE FUNCTION; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MODIFICATION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANOXIA; EXTRACELLULAR MATRIX PROTEINS; FLAVOPROTEINS; NADPH OXIDASE; PHAGOCYTES; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 0036134932     PISSN: 10656251     EISSN: None     Source Type: Journal    
DOI: 10.1097/00062752-200201000-00003     Document Type: Review

References (51)

1. Oxidants from phagocytes: Agents of defense and destruction
2. Radicals r′ aging
3. 2) superoxide dismutases, and related matters
4. Novel gp91 phox homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
5. 2 for platelet-derived growth factor signal transduction
6. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide
7. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
8. Cell transformation by the superoxide-generating oxidase Mox1
9. Novel homologs of gp91phox
10. Regulation of the phagocyte respiratory burst oxidase by protein interactions
11. The NADPH oxidase of phagocytic leukocytes
12. Regulation of the neutrophil respiratory burst oxidase: Identification of an activation domain in p67phox
13. 558
14. Expression of phagocyte NADPH oxidase components in human endothelial cells
15. The expression of NADPH oxidase components in human glomerular mesangial cells: Detection of protein and mRNA for p47phox, p67phox, and p22phox
16. The functional expression of p47-phox and p67-phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts
17. Enzymic mechanisms of superoxide production
18. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
19. 2-generating NADH oxidase in human lung fibroblasts by transforming growth factor β1
20. Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumor necrosis factor-a
21. Production of oxygen radicals by fibroblasts and neutrophils from a patient with x-linked chronic granulomatous disease
22. Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1
23. Induction of cyclooxygenase-2 by the activated MEKK1->SEK1/MKK4->p38 mitogen-activated protein kinase pathway
24. Homologs of gp91phox: Cloning and tissue expression of Nox3, Nox4, and Nox5
25. Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91 phox
26. NADPH oxidase subunit, gp91phox homolog, preferentially expressed in human colon epithelial cells
27. Purification of a novel flavoprotein involved in the thyroid NADPH oxidase
28. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
29. A Ca2+-activated NADPH oxidase in testis, spleen and lymph nodes
30. A new superoxide-generating oxidase in murine osteoclasts
31. Identification of Renox, an NAD(P)H oxidase in kidney
32. A novel superoxide-producing NAD(P)H oxidase in kidney
33. Intramembrane bis-heme motif for transmembrane electron transport conserved in a yeast iron reductase and the human NADPH oxidase
34. 885
35. Characterization of the flavoprotein domain of gp91 phox which has NADPH diaphorase activity
36. Heme-ligating histidines in flavocytochrome b558: Identification of specific histidines in gp91 phox
37. Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (Thex1, LNOX, Duox) genes and proteins in human thyroid tissues
38. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with a H+ channel
39. Role of histidines identified by mutagenesis in the NADPH oxidase-associated H+ channel
40. The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps
41. A mammalian H+ channel generated • through alternative splicing of the NADPH oxidase homolog NOH-1
42. Production of large amounts of hydrogen peroxide by humor tumor cells
43. Reversible inactivation of protein tyrosine phosphatase 1 B in A431 cells stimulated with epidermal growth factor
44. Cyclophilin A is a secreted growth factor induced by oxidative stress
45. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
46. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
47. Hypoxia and the regulation of gene expression
48. Superoxide and bone resorption
49. Thyroid exidase (THOX2) gene expression in the rat thyroid cel line FRTL-5
50. Expression of NADPH oxidase flaveprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas