Activation of integrins by urea in perfused rat liver

Journal of Biological Chemistry

Volumn 285, Issue 38, 2010, Pages 29348-29356

  Reinehr, Roland ^a   Gohlke, Holger ^a   Sommerfeld, Annika ^a   Vom Dahl, Stephan ^a   Häussinger, Dieter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CHEMICAL ACTIVATION; ENZYME ACTIVITY; GLYCOPROTEINS; METABOLISM; MOLECULAR DYNAMICS; THIOUREAS; THREE DIMENSIONAL;

C-JUN N-TERMINAL KINASE; CHANNEL OPENING; CONFORMATIONAL CHANGE; DIRECT ACTIVATION; ECTODOMAIN; EXTRACELLULAR SIGNAL-REGULATED KINASE; FOCAL ADHESION KINASE; HEPATOCYTES; HIGH CONCENTRATION; IN-LINE; INTEGRINS; MOLECULAR DYNAMICS SIMULATIONS; P38 MAPK; PLASMA MEMBRANES; RAT LIVERS; REGULATORY VOLUME DECREASE; SINGLE DOMAINS; THREE-DIMENSIONAL MODEL; UNDERLYING MECHANISM;

UREA;

BETA1 INTEGRIN; FOCAL ADHESION KINASE; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; POTASSIUM ION; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; THIOUREA; UREA; VERY LATE ACTIVATION ANTIGEN 5; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SWELLING; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; LIVER CELL; LIVER METABOLISM; LIVER PERFUSION; MALE; MOLECULAR DYNAMICS; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CHEMICAL STRUCTURE; DRUG EFFECTS; GENETICS; IN VITRO STUDY; LIVER; METABOLISM; PERFUSION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; WESTERN BLOTTING; WISTAR RAT;

RATTUS;

ANIMALS; BLOTTING, WESTERN; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HEPATOCYTES; IN VITRO TECHNIQUES; INTEGRIN ALPHA5BETA1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MALE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERFUSION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; RATS; RATS, WISTAR; THIOUREA; UREA;

EID: 77956511866     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.155135     Document Type: Article

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