-
1
-
-
0030597194
-
Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains
-
Adler, K., Gerisch, G., von Hugo, U., Lupas, A. & Schweiger, A. 1996 Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains. FEBS Lett. 395, 286-292.
-
(1996)
FEBS Lett.
, vol.395
, pp. 286-292
-
-
Adler, K.1
Gerisch, G.2
Von Hugo, U.3
Lupas, A.4
Schweiger, A.5
-
2
-
-
0028931552
-
Neurotrophic factors and their receptors
-
Barbacid, M. 1995 Neurotrophic factors and their receptors. Curr. Opin. Cell Biol. 7, 148-155.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 148-155
-
-
Barbacid, M.1
-
3
-
-
0029940385
-
Identification of a binding site in c-Abl tyrosine kinase for the G-terminal repeated domain of RNA polymerase II
-
Baskaran, R., Chiang, G. C. & Wang, J. Y. J. 1996 Identification of a binding site in c-Abl tyrosine kinase for the G-terminal repeated domain of RNA polymerase II. Molec. Cell Biol. 16, 3361-3369.
-
(1996)
Molec. Cell Biol.
, vol.16
, pp. 3361-3369
-
-
Baskaran, R.1
Chiang, G.C.2
Wang, J.Y.J.3
-
4
-
-
0027361837
-
Tyrosine phosphorylation of mammalian RNA polymerase II carboxylterminal domain
-
Baskaran, R., Dahmus, M. F. & Wang, J. Y. J. 1993 Tyrosine phosphorylation of mammalian RNA polymerase II carboxylterminal domain. Proc. Natn. Acad. Sci. USA 90, 11167-11171.
-
(1993)
Proc. Natn. Acad. Sci. USA
, vol.90
, pp. 11167-11171
-
-
Baskaran, R.1
Dahmus, M.F.2
Wang, J.Y.J.3
-
5
-
-
0027957389
-
Prokaryotic expression cloning of a novel human tyrosine kinase
-
Beeler, J. F., LaRochelle, W. J., Chedid, M., Tronick, S. R. & Aaronson, S. A. 1994 Prokaryotic expression cloning of a novel human tyrosine kinase. Molec. Cell Biol. 14, 982-988.
-
(1994)
Molec. Cell Biol.
, vol.14
, pp. 982-988
-
-
Beeler, J.F.1
LaRochelle, W.J.2
Chedid, M.3
Tronick, S.R.4
Aaronson, S.A.5
-
6
-
-
0029759927
-
Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization
-
Bilwes, A. M., den Hertog, J., Hunter, T. & Noel, J. P. 1996 Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization. Nature 382, 555-559.
-
(1996)
Nature
, vol.382
, pp. 555-559
-
-
Bilwes, A.M.1
Den Hertog, J.2
Hunter, T.3
Noel, J.P.4
-
7
-
-
0030913232
-
Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein-tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions
-
Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein-tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions. EMBO J. 16, 2730-2744.
-
(1997)
EMBO J.
, vol.16
, pp. 2730-2744
-
-
Black, D.S.1
Bliska, J.B.2
-
8
-
-
0024742755
-
Structure and expression of STK, a src-related gene in the simple metazoan Hydra attenuata
-
Bosch, T. C. G., Unger, T. F., Fisher, D. A. & Steele, R. E. 1989 Structure and expression of STK, a src-related gene in the simple metazoan Hydra attenuata. Molec. Cell Biol. 9, 4141-4151.
-
(1989)
Molec. Cell Biol.
, vol.9
, pp. 4141-4151
-
-
Bosch, T.C.G.1
Unger, T.F.2
Fisher, D.A.3
Steele, R.E.4
-
9
-
-
0029067124
-
Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells
-
Bourette, R. P., Myles, G. M., Carlberg, K., Chen, A. R. & Rohrschneider, L. R. 1995 Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells. Cell Growth Diff. 6, 631-645.
-
(1995)
Cell Growth Diff.
, vol.6
, pp. 631-645
-
-
Bourette, R.P.1
Myles, G.M.2
Carlberg, K.3
Chen, A.R.4
Rohrschneider, L.R.5
-
10
-
-
0029149746
-
Receptor protein tyrosine phosphatase PTPμ associates with cadherins and catenins in vivo
-
Brady-Kalnay, S. M., Rimm, D. L. & Tonks, N. K. 1995 Receptor protein tyrosine phosphatase PTPμ associates with cadherins and catenins in vivo. J. Cell Biol. 130, 977-986.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 977-986
-
-
Brady-Kalnay, S.M.1
Rimm, D.L.2
Tonks, N.K.3
-
11
-
-
0028180234
-
4,5-Dianilinophthalimide: A protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity
-
Buchdunger, E., Trinks, U., Mett, H., Regenass, U., Muller, M., Meyer, T., McGlynn, E., Pinna, L. A., Traxler, P. & Lydon, N. B. 1994 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc. Natn. Acad. Sci. USA 91, 2334-2338.
-
(1994)
Proc. Natn. Acad. Sci. USA
, vol.91
, pp. 2334-2338
-
-
Buchdunger, E.1
Trinks, U.2
Mett, H.3
Regenass, U.4
Muller, M.5
Meyer, T.6
McGlynn, E.7
Pinna, L.A.8
Traxler, P.9
Lydon, N.B.10
-
12
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R. & Soltoff, S. 1991 Oncogenes and signal transduction. Cell 64, 281-302.
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
Soltoff, S.7
-
13
-
-
0031459864
-
P62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous Leukaemia progenitor cells
-
Carpino, N., Wisniewski, D., Strife, A., Marshak, D., Kobayashi, R., Stillman, B. & Clarkson, B. 1997 p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous Leukaemia progenitor cells. Cell 88, 197-204.
-
(1997)
Cell
, vol.88
, pp. 197-204
-
-
Carpino, N.1
Wisniewski, D.2
Strife, A.3
Marshak, D.4
Kobayashi, R.5
Stillman, B.6
Clarkson, B.7
-
14
-
-
0028349867
-
Identification of a gene encoding a novel protein-tyrosine kinase containing SH2 domains and ankyrin-like repeats
-
Chan, T. A., Chu, G. A., Rauen, K. A., Kroiher, M., Tatarewicz, S. M. & Steele, R. E. 1994a Identification of a gene encoding a novel protein-tyrosine kinase containing SH2 domains and ankyrin-like repeats. Oncogens 9, 1253-1259.
-
(1994)
Oncogens
, vol.9
, pp. 1253-1259
-
-
Chan, T.A.1
Chu, G.A.2
Rauen, K.A.3
Kroiher, M.4
Tatarewicz, S.M.5
Steele, R.E.6
-
15
-
-
0028340167
-
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
-
Chan, A. C., Kadlecek, T. A., Elder, M. E., Filipovich, A. H., Kuo, W. L., Iwashima, M., Parslow, T. G. & Weiss, A. 1994b ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264, 599-601.
-
(1994)
Science
, vol.264
, pp. 599-601
-
-
Chan, A.C.1
Kadlecek, T.A.2
Elder, M.E.3
Filipovich, A.H.4
Kuo, W.L.5
Iwashima, M.6
Parslow, T.G.7
Weiss, A.8
-
16
-
-
0028987936
-
Integrins and signal transduction pathways: The road taken
-
Clark, E. A. & Brugge, J. S. 1995 Integrins and signal transduction pathways: the road taken. Science 268, 233-239.
-
(1995)
Science
, vol.268
, pp. 233-239
-
-
Clark, E.A.1
Brugge, J.S.2
-
18
-
-
0020357523
-
Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins
-
Cooper, J. A., Bowen-Pope, D., Raines, E., Ross, R. & Hunter, T. 1982 Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins. Cell 31, 263-273.
-
(1982)
Cell
, vol.31
, pp. 263-273
-
-
Cooper, J.A.1
Bowen-Pope, D.2
Raines, E.3
Ross, R.4
Hunter, T.5
-
20
-
-
0019434891
-
Changes in protein phosphorylation in Rous sarcoma virus transformed chicken embryo cells
-
Cooper, J. A. & Hunter, T. 1981 Changes in protein phosphorylation in Rous sarcoma virus transformed chicken embryo cells. Molec. Cell Biol. 1, 165-178.
-
(1981)
Molec. Cell Biol.
, vol.1
, pp. 165-178
-
-
Cooper, J.A.1
Hunter, T.2
-
22
-
-
0022081671
-
c-src kinase by middle T antigen binding or by dephosphorylation
-
c-src kinase by middle T antigen binding or by dephosphorylation. EMBO J. 4, 1471-1477.
-
(1985)
EMBO J.
, vol.4
, pp. 1471-1477
-
-
Courtneidge, S.1
-
23
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E., Kerr, I. M. & Stark, G. R. 1994 Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
24
-
-
15844417385
-
The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo
-
DeChiara, T. M. (and 14 others) 1996 The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell 85, 501-512.
-
(1996)
Cell
, vol.85
, pp. 501-512
-
-
Dechiara, T.M.1
-
25
-
-
0029949837
-
Tight association of GRB2 with receptor protein-tyrosine phosphatase a is mediated by the SH2 and C-terminal SH3 domains
-
den Hertog, J. & Hunter, T. 1996 Tight association of GRB2 with receptor protein-tyrosine phosphatase a is mediated by the SH2 and C-terminal SH3 domains. EMBO J. 15, 3016-3027.
-
(1996)
EMBO J.
, vol.15
, pp. 3016-3027
-
-
Den Hertog, J.1
Hunter, T.2
-
26
-
-
0028285788
-
Phosphorylation of receptor protein-tyrosine phosphatase a on tyrosine 789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo
-
den Hertog, J., Tracy, S. & Hunter, T. 1994 Phosphorylation of receptor protein-tyrosine phosphatase a on tyrosine 789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo. EMBO J. 13, 3020-3032.
-
(1994)
EMBO J.
, vol.13
, pp. 3020-3032
-
-
Den Hertog, J.1
Tracy, S.2
Hunter, T.3
-
27
-
-
0031051796
-
Tyrosine phosphorylation and axon guidance: Of mice and flies
-
Desai, C. J., Sun, Q. & Zinn, K. 1997 Tyrosine phosphorylation and axon guidance: of mice and flies. Curr. Opin. Neurobiol. 7, 70-74.
-
(1997)
Curr. Opin. Neurobiol.
, vol.7
, pp. 70-74
-
-
Desai, C.J.1
Sun, Q.2
Zinn, K.3
-
28
-
-
0028485768
-
PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation
-
Dikic, I., Schlessinger, J. & Lax, I. 1994 PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Curr. Biol. 4, 702-708.
-
(1994)
Curr. Biol.
, vol.4
, pp. 702-708
-
-
Dikic, I.1
Schlessinger, J.2
Lax, I.3
-
29
-
-
0030010590
-
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
-
Eck, M. J., Dhe-Paganon, S., Trub, T., Nolte, R. T. & Shoelson, S. E. 1996 Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor. Cell 85, 695-705.
-
(1996)
Cell
, vol.85
, pp. 695-705
-
-
Eck, M.J.1
Dhe-Paganon, S.2
Trub, T.3
Nolte, R.T.4
Shoelson, S.E.5
-
30
-
-
0018580807
-
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates
-
Eckhart, W., Hutchinson, M. A. & Hunter, T. 1979 An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates. Cell 18, 925-933.
-
(1979)
Cell
, vol.18
, pp. 925-933
-
-
Eckhart, W.1
Hutchinson, M.A.2
Hunter, T.3
-
31
-
-
0020034489
-
Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor
-
Ek, B., Westermark, B., Wasteson, A. & Heldin, C.-H. 1982 Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor. Nature 295, 419-420.
-
(1982)
Nature
, vol.295
, pp. 419-420
-
-
Ek, B.1
Westermark, B.2
Wasteson, A.3
Heldin, C.-H.4
-
32
-
-
0018945601
-
Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus transforming gene product
-
Erikson, E. & Erikson, R. L. 1980 Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus transforming gene product. Cell 21, 829-836.
-
(1980)
Cell
, vol.21
, pp. 829-836
-
-
Erikson, E.1
Erikson, R.L.2
-
33
-
-
0031150017
-
The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction
-
Frearson, J. A. & Alexander, D. R. 1997 The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction. Bioessays 19, 417-427.
-
(1997)
Bioessays
, vol.19
, pp. 417-427
-
-
Frearson, J.A.1
Alexander, D.R.2
-
34
-
-
0029943807
-
Eph receptor tyrosine kinases and their ligands in neural development
-
Friedman, G. C. & O'Leary, D. D. 1996 Eph receptor tyrosine kinases and their ligands in neural development. Curr. Opin. Neurobiol. 6, 127-133.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 127-133
-
-
Friedman, G.C.1
O'Leary, D.D.2
-
35
-
-
0028142387
-
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
-
Fry, D. W., Kraker, A. J., McMichael, A., Ambroso, L. A., Nelson, J. M., Leopold, W. R., Connors, R. W. & Bridges, A. J. 1994 A specific inhibitor of the epidermal growth factor receptor tyrosine kinase. Science 265, 1093-1095.
-
(1994)
Science
, vol.265
, pp. 1093-1095
-
-
Fry, D.W.1
Kraker, A.J.2
McMichael, A.3
Ambroso, L.A.4
Nelson, J.M.5
Leopold, W.R.6
Connors, R.W.7
Bridges, A.J.8
-
36
-
-
0028821383
-
HIV-1 infection of non-dividing cells: C-terminal tyrosine phosphorylation of matrix protein is a key regulator
-
Gallay, P., Swingler, S., Aiken, C. & Trono, D. 1995 HIV-1 infection of non-dividing cells: C-terminal tyrosine phosphorylation of matrix protein is a key regulator. Cell 80, 379-388.
-
(1995)
Cell
, vol.80
, pp. 379-388
-
-
Gallay, P.1
Swingler, S.2
Aiken, C.3
Trono, D.4
-
37
-
-
15844380040
-
Agrin acts via a MuSK receptor complex
-
Glass, D. J. (and 13 others) 1996 Agrin acts via a MuSK receptor complex. Cell 85, 513-523.
-
(1996)
Cell
, vol.85
, pp. 513-523
-
-
Glass, D.J.1
-
38
-
-
0025760751
-
Regulation of phospholipase C-γl by profilin and tyrosine phosphorylation
-
Goldschmidt-Clermont, P. J., Kim, J. W., Machesky, L. M., Rhee, S. G. & Pollard, T. D. 1991 Regulation of phospholipase C-γl by profilin and tyrosine phosphorylation. Science 251, 1231-1233.
-
(1991)
Science
, vol.251
, pp. 1231-1233
-
-
Goldschmidt-Clermont, P.J.1
Kim, J.W.2
Machesky, L.M.3
Rhee, S.G.4
Pollard, T.D.5
-
39
-
-
0028224348
-
Fusion of PDGF receptor β to a novel ets-like. gene, tel, in chronic myelomonocytic leukaemia with t(5;12) chromosomal translocation
-
Golub, T. R., Barker, G. F., Lovett, M. & Gilliland, D. G. 1994 Fusion of PDGF receptor β to a novel ets-like. gene, tel, in chronic myelomonocytic leukaemia with t(5;12) chromosomal translocation. Cell 77, 307-316.
-
(1994)
Cell
, vol.77
, pp. 307-316
-
-
Golub, T.R.1
Barker, G.F.2
Lovett, M.3
Gilliland, D.G.4
-
40
-
-
0024959919
-
+ protein kinase regulates entry into mitosis
-
+ protein kinase regulates entry into mitosis. Nature 342, 39-45.
-
(1989)
Nature
, vol.342
, pp. 39-45
-
-
Gould, K.L.1
Nurse, P.2
-
41
-
-
0026600358
-
TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas
-
Greco, A., Pierotti, M. A., Bongarzone, I., Pagliardini, S., Lanzi, C. & Della Porta, G. 1992 TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas. Oncogene 7, 237-242.
-
(1992)
Oncogene
, vol.7
, pp. 237-242
-
-
Greco, A.1
Pierotti, M.A.2
Bongarzone, I.3
Pagliardini, S.4
Lanzi, C.5
Della Porta, G.6
-
42
-
-
0029020282
-
Protein kinases. 6. the eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
-
Hanks, S. K. & Hunter, T. 1995 Protein kinases. 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9, 576-596.
-
(1995)
FASEB J.
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
43
-
-
0031081425
-
Signaling through focal adhesion kinase
-
Hanks, S. K. & Polte, T. R. 1997 Signaling through focal adhesion kinase. Bioessqys 19, 137-145.
-
(1997)
Bioessqys
, vol.19
, pp. 137-145
-
-
Hanks, S.K.1
Polte, T.R.2
-
44
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
-
Hanks, S. K., Quinn, A. M. & Hunter, T. 1988 The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241, 42-52.
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
45
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin, C. H. 1995 Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223.
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
46
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill, C. S. & Treisman, R. 1995 Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80, 199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.S.1
Treisman, R.2
-
47
-
-
0030473947
-
Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain
-
Holmes, T. C., Fadool, D. A., Ren, R. & Levitan, I. B. 1996 Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain. Science 274, 2089-2091.
-
(1996)
Science
, vol.274
, pp. 2089-2091
-
-
Holmes, T.C.1
Fadool, D.A.2
Ren, R.3
Levitan, I.B.4
-
48
-
-
0024232854
-
Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation
-
Hopfield, J. F., Tank, D. W., Greengard, P. & Huganir, R. L. 1988 Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation. Nature 336, 677-680.
-
(1988)
Nature
, vol.336
, pp. 677-680
-
-
Hopfield, J.F.1
Tank, D.W.2
Greengard, P.3
Huganir, R.L.4
-
49
-
-
0027146670
-
Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled ml muscarinic acetylcholine receptor
-
Huang, X.-Y., Morielli, A. D. & Peralta, E. G. 1993 Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled ml muscarinic acetylcholine receptor. Cell 75, 1145-1156.
-
(1993)
Cell
, vol.75
, pp. 1145-1156
-
-
Huang, X.-Y.1
Morielli, A.D.2
Peralta, E.G.3
-
50
-
-
0028582185
-
Crystal structure of the tyrosine kinase domain of the human insulin receptor
-
Hubbard, S. R., Wei, L., Ellis, L. & Hendrickson, W. A. 1994 Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 372, 746-754.
-
(1994)
Nature
, vol.372
, pp. 746-754
-
-
Hubbard, S.R.1
Wei, L.2
Ellis, L.3
Hendrickson, W.A.4
-
51
-
-
0023649678
-
A tail of two src's: Mutatis mutandis
-
Hunter,T. 1987a A tail of two src's: mutatis mutandis. Cell 49, 1-4.
-
(1987)
Cell
, vol.49
, pp. 1-4
-
-
Hunter, T.1
-
52
-
-
0023651349
-
A thousand and one protein kinases
-
Hunter, T. 1987b A thousand and one protein kinases. Cell 50, 823-829.
-
(1987)
Cell
, vol.50
, pp. 823-829
-
-
Hunter, T.1
-
53
-
-
0019413616
-
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells
-
Hunter, T. & Cooper, J. A. 1981 Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell 24, 741-752.
-
(1981)
Cell
, vol.24
, pp. 741-752
-
-
Hunter, T.1
Cooper, J.A.2
-
54
-
-
0031026008
-
The protein kinases of yeast: Six score and more
-
Hunter, T. & Plowman, G. D. 1997 The protein kinases of yeast: six score and more. Trends Biochem. Sci. 22, 18-22.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 18-22
-
-
Hunter, T.1
Plowman, G.D.2
-
55
-
-
0000109995
-
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
-
Hunter, T. & Sefton, B. M. 1980 Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc. Natn. Acad. Sci. USA 77, 1311-1315.
-
(1980)
Proc. Natn. Acad. Sci. USA
, vol.77
, pp. 1311-1315
-
-
Hunter, T.1
Sefton, B.M.2
-
56
-
-
0028845212
-
Cytokine receptor signalling
-
Ihle, J. N. 1995 Cytokine receptor signalling. Nature 377, 591-594.
-
(1995)
Nature
, vol.377
, pp. 591-594
-
-
Ihle, J.N.1
-
57
-
-
0029975479
-
Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation
-
Jayaraman, T., Ondrias, K., Ondriasova, E. & Marks, A. R. 1996 Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation. Science 272, 1492-1494.
-
(1996)
Science
, vol.272
, pp. 1492-1494
-
-
Jayaraman, T.1
Ondrias, K.2
Ondriasova, E.3
Marks, A.R.4
-
59
-
-
0029328342
-
Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
-
Karin, M. & Hunter, T. 1995 Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr. Biol. 5, 747-757.
-
(1995)
Curr. Biol.
, vol.5
, pp. 747-757
-
-
Karin, M.1
Hunter, T.2
-
60
-
-
0020065416
-
Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor
-
Kasuga, M., Karlsson, F. A. & Kahn, C. R. 1981 Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor. Science 215, 185-187.
-
(1981)
Science
, vol.215
, pp. 185-187
-
-
Kasuga, M.1
Karlsson, F.A.2
Kahn, C.R.3
-
61
-
-
0030807903
-
SH2 signaling in a lower eukaryote: A STAT protein that regulates stalk cell differentiation in Dictyostelium
-
Kawata, T., Shevchenko, A., Fukuzawa, M., Jermyn, K. A., Totty, N. F., Zhukovskaya, N. V., Sterling, A. E., Mann, M. & Williams, J. G. 1997 SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in Dictyostelium. Cell 89, 909-916.
-
(1997)
Cell
, vol.89
, pp. 909-916
-
-
Kawata, T.1
Shevchenko, A.2
Fukuzawa, M.3
Jermyn, K.A.4
Totty, N.F.5
Zhukovskaya, N.V.6
Sterling, A.E.7
Mann, M.8
Williams, J.G.9
-
62
-
-
0025805394
-
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254
-
Kim, H. K., Kim, J. W., Zilberstein, A., Margolis, B., Kim, J. G., Schlessinger, J. & Rhee, S. G. 1991 PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254. Cell 65, 435-441.
-
(1991)
Cell
, vol.65
, pp. 435-441
-
-
Kim, H.K.1
Kim, J.W.2
Zilberstein, A.3
Margolis, B.4
Kim, J.G.5
Schlessinger, J.6
Rhee, S.G.7
-
63
-
-
0030706168
-
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
-
Kouhara, H., Hadari, Y. R., Spivak-Kroizman, T., Schilling, J., Bar-Sagi, D., Lax, I. & Schlessinger, J. 1997 A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89, 693-702.
-
(1997)
Cell
, vol.89
, pp. 693-702
-
-
Kouhara, H.1
Hadari, Y.R.2
Spivak-Kroizman, T.3
Schilling, J.4
Bar-Sagi, D.5
Lax, I.6
Schlessinger, J.7
-
64
-
-
0030467394
-
Regulation of STAT-dependent pathways by growth factors and cytokines
-
Leaman, D. W., Leung, S., Li, X. & Stark, G. R. 1996 Regulation of STAT-dependent pathways by growth factors and cytokines. FASEB J. 10, 1578-1588.
-
(1996)
FASEB J.
, vol.10
, pp. 1578-1588
-
-
Leaman, D.W.1
Leung, S.2
Li, X.3
Stark, G.R.4
-
65
-
-
0031006326
-
Regulatory recruitment of signalling molecules to the cell membrane by pleckstrin homology domains
-
Lemmon, M. A., Falasca, M., Ferguson, K. M. & Schlessinger, J. 1997 Regulatory recruitment of signalling molecules to the cell membrane by pleckstrin homology domains. Trends Cell Biol. 7, 237-242.
-
(1997)
Trends Cell Biol.
, vol.7
, pp. 237-242
-
-
Lemmon, M.A.1
Falasca, M.2
Ferguson, K.M.3
Schlessinger, J.4
-
66
-
-
0028252924
-
Steel factor and c-kit proto-oncogene: Genetic lessons in signal transduction
-
Lev, S., Blechman, J. M., Givol, D. & Yarden, Y. 1994 Steel factor and c-kit proto-oncogene: genetic lessons in signal transduction. Crit. Rev. Oncog. 5, 141-168.
-
(1994)
Crit. Rev. Oncog.
, vol.5
, pp. 141-168
-
-
Lev, S.1
Blechman, J.M.2
Givol, D.3
Yarden, Y.4
-
67
-
-
0029154733
-
2+-induced regulation of ion channel and MAP kinase functions (see comments)
-
2+-induced regulation of ion channel and MAP kinase functions (see comments). Nature 376, 737-745.
-
(1995)
Nature
, vol.376
, pp. 737-745
-
-
Lev, S.1
Moreno, H.2
Martinez, R.3
Canoll, P.4
Peles, E.5
Musacchio, J.M.6
Plowman, G.D.7
Rudy, B.8
Schlessinger, J.9
-
68
-
-
0029925701
-
Targeting signal transduction for disease therapy
-
Levitzki, A. 1996 Targeting signal transduction for disease therapy. Curr. Opin. Cell Biol. 8, 239-244.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 239-244
-
-
Levitzki, A.1
-
69
-
-
0028968949
-
Tyrosine kinase inhibition: An approach to drug development
-
Levitzki, A. & Gazit, A. 1995 Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782-1788.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
70
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li, J. (and 16 others) 1997 PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
-
71
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D. (and 11 others) 1997 Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16, 64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
-
72
-
-
10144243337
-
A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells
-
Lupher, M. L., Reedquist, K. A., Miyake, S., Langdon, W. Y. & Band, H. 1996 A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells. J. Biol. Chem. 271, 24063-24068.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24063-24068
-
-
Lupher, M.L.1
Reedquist, K.A.2
Miyake, S.3
Langdon, W.Y.4
Band, H.5
-
73
-
-
0024345772
-
EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling
-
Margolis, B., Rhee, S. G., Felder, S., Mervic, M., Lyall, R., Levitzki, A., Ullrich, A., Zilberstein, A. & Schlessinger, J. 1989 EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling. Cell 57, 1101-1107.
-
(1989)
Cell
, vol.57
, pp. 1101-1107
-
-
Margolis, B.1
Rhee, S.G.2
Felder, S.3
Mervic, M.4
Lyall, R.5
Levitzki, A.6
Ullrich, A.7
Zilberstein, A.8
Schlessinger, J.9
-
74
-
-
0028152333
-
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
-
Marshall, C. J. 1994 MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr. Opin. Gen. Dev. 4, 82-89.
-
(1994)
Curr. Opin. Gen. Dev.
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
75
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. 1995 Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
76
-
-
0022641294
-
A human oncogene formed by the fusion of truncated tropomyosin and protein-tyrosine kinase sequences
-
Martin-Zanca, D., Hughes, S. H. & Barbacid, M. 1986 A human oncogene formed by the fusion of truncated tropomyosin and protein-tyrosine kinase sequences. Nature 319, 743-748.
-
(1986)
Nature
, vol.319
, pp. 743-748
-
-
Martin-Zanca, D.1
Hughes, S.H.2
Barbacid, M.3
-
77
-
-
0030272507
-
X-linked agammaglobulinemia (XLA): A genetic tyrosine kinase (Btk) disease
-
Mattsson, P. T., Vihinen, M. & Smith, G. I. E. 1996 X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) disease. Bioessays 18, 825-834.
-
(1996)
Bioessays
, vol.18
, pp. 825-834
-
-
Mattsson, P.T.1
Vihinen, M.2
Smith, G.I.E.3
-
78
-
-
0024380391
-
Phospholipase C-γ is a substrate for the PDGFand EGF receptor protein-tyrosine kinases in viro and in vitro
-
Meisenhelder, J., Suh, P.-G., Rhee, S. G. & Hunter, T. 1989 Phospholipase C-γ is a substrate for the PDGFand EGF receptor protein-tyrosine kinases in viro and in vitro. Cell 57, 1109-1122.
-
(1989)
Cell
, vol.57
, pp. 1109-1122
-
-
Meisenhelder, J.1
Suh, P.-G.2
Rhee, S.G.3
Hunter, T.4
-
79
-
-
0027451706
-
The extracellular matrix as a cell survival factor
-
Meredith, J. E., Fazeli, B. & Schwartz, M. A. 1993 The extracellular matrix as a cell survival factor. Molec. Biol. Cell 4, 953-961.
-
(1993)
Molec. Biol. Cell
, vol.4
, pp. 953-961
-
-
Meredith, J.E.1
Fazeli, B.2
Schwartz, M.A.3
-
80
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan, N. (and 11 others) 1996 Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 379, 645-648.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
-
81
-
-
0030945871
-
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
-
Mohammadi, M., McMahon, G., Sun, L., Tang, C., Hirth, P., Yeh, B. K., Hubbard, S. R. & Schlessinger, J. 1997 Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276, 955-960.
-
(1997)
Science
, vol.276
, pp. 955-960
-
-
Mohammadi, M.1
McMahon, G.2
Sun, L.3
Tang, C.4
Hirth, P.5
Yeh, B.K.6
Hubbard, S.R.7
Schlessinger, J.8
-
82
-
-
0028931265
-
Principles of CDK regulation
-
Morgan, D. O. 1995 Principles of CDK regulation. Nature 374, 131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
83
-
-
0024390591
-
Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis
-
Morla, A. O., Draetta, G., Beach, D. & Wang, J. Y. J. 1989 Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis. Cell 58, 193-203.
-
(1989)
Cell
, vol.58
, pp. 193-203
-
-
Morla, A.O.1
Draetta, G.2
Beach, D.3
Wang, J.Y.J.4
-
84
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris, S. W., Kirstein, M. N., Valentine, M. B., Dittmer, K. G., Shapiro, D. N., Saltman, D. L. & Look, A. T. 1994 Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 263, 1281-1284.
-
(1994)
Science
, vol.263
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
Dittmer, K.G.4
Shapiro, D.N.5
Saltman, D.L.6
Look, A.T.7
-
85
-
-
0030072570
-
Vertebrate non-receptor protein-tyrosine kinase families
-
Neet, K. & Hunter, T. 1996 Vertebrate non-receptor protein-tyrosine kinase families. Genes Cells 1, 147-169.
-
(1996)
Genes Cells
, vol.1
, pp. 147-169
-
-
Neet, K.1
Hunter, T.2
-
86
-
-
0030452455
-
Molecular biology of axon guidance
-
Nieto, M. A. 1996 Molecular biology of axon guidance. Neuron 17, 1039-1048.
-
(1996)
Neuron
, vol.17
, pp. 1039-1048
-
-
Nieto, M.A.1
-
87
-
-
0025605968
-
Increase of the catalytic activity of phospholipase C-γl by tyrosine phosphorylation
-
Nishibe, S., Wahl, M. I., Hernandez-Sotomayor, S. M. T., Tonks, N. K., Rhee, S. G. & Carpenter, G. 1990 Increase of the catalytic activity of phospholipase C-γl by tyrosine phosphorylation. Science 250, 1253-1256.
-
(1990)
Science
, vol.250
, pp. 1253-1256
-
-
Nishibe, S.1
Wahl, M.I.2
Hernandez-Sotomayor, S.M.T.3
Tonks, N.K.4
Rhee, S.G.5
Carpenter, G.6
-
88
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka, T., van Deursen, J. M., Tripp, R. A., Thierfelder, W. E., Witthuhn, B. A., McMickle, A. P., Doherty, P. C., Grosveld, G. C. & Ihle, J. N. 1995 Defective lymphoid development in mice lacking Jak3. Science 270, 800-802.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
Van Deursen, J.M.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
Doherty, P.C.7
Grosveld, G.C.8
Ihle, J.N.9
-
89
-
-
0030472832
-
Requirement for Y706 of the murine (or Y708 of the human) CSF-1 receptor for STAT1 activation in response to CSF-1
-
Novak, U., Nice, E., Hamilton, J. A. & Paradiso, L. 1996 Requirement for Y706 of the murine (or Y708 of the human) CSF-1 receptor for STAT1 activation in response to CSF-1. Oncogene 13, 2607-2613.
-
(1996)
Oncogene
, vol.13
, pp. 2607-2613
-
-
Novak, U.1
Nice, E.2
Hamilton, J.A.3
Paradiso, L.4
-
90
-
-
0029851378
-
The Dictyostelium dual-specificity kinase splA is essential for spore differentiation
-
Nuckolls, G. H., Osherov, N., Loomis, W. F. & Spudich, J. A. 1996 The Dictyostelium dual-specificity kinase splA is essential for spore differentiation. Development 122, 3295-3305.
-
(1996)
Development
, vol.122
, pp. 3295-3305
-
-
Nuckolls, G.H.1
Osherov, N.2
Loomis, W.F.3
Spudich, J.A.4
-
91
-
-
0026771267
-
Multiple src-related kinase genes, srk1-4, in the fresh water sponge Spongilla lacustris
-
Ottilie, S., Raulf, F., Barnekow, A., Hannig, G. & Schartl, M. 1992 Multiple src-related kinase genes, srk1-4, in the fresh water sponge Spongilla lacustris. Oncogene 7, 1625-1630.
-
(1992)
Oncogene
, vol.7
, pp. 1625-1630
-
-
Ottilie, S.1
Raulf, F.2
Barnekow, A.3
Hannig, G.4
Schartl, M.5
-
92
-
-
0028859279
-
Protein modules and signalling networks
-
Pawson, T. 1995 Protein modules and signalling networks. Nature 373, 573-580.
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
93
-
-
0029096048
-
The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin
-
Peles, E. (and 11 others) 1995 The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin. Cell 82, 251-260.
-
(1995)
Cell
, vol.82
, pp. 251-260
-
-
Peles, E.1
-
94
-
-
0030978909
-
The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions
-
Persson, C., Carballeira, N., Wolf-Watz, H. & Fallman, M. 1997 The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions. EMBO J. 16, 2307-2318.
-
(1997)
EMBO J.
, vol.16
, pp. 2307-2318
-
-
Persson, C.1
Carballeira, N.2
Wolf-Watz, H.3
Fallman, M.4
-
95
-
-
0027970838
-
Chromosomal translocations in human cancer
-
Rabbitts, T. H. 1994 Chromosomal translocations in human cancer. Nature 372, 143-149.
-
(1994)
Nature
, vol.372
, pp. 143-149
-
-
Rabbitts, T.H.1
-
96
-
-
0018959961
-
Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine
-
Radke, K., Gilmore, T. & Martin, G. S. 1980 Transformation by Rous sarcoma virus: a cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine. Cell 21, 821-828.
-
(1980)
Cell
, vol.21
, pp. 821-828
-
-
Radke, K.1
Gilmore, T.2
Martin, G.S.3
-
97
-
-
0026608462
-
Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: A model for SH2-mediated receptor-target interactions
-
Reedijk, M., Liu, X., van der Geer, P., Letwin, K., Waterfield, M. D., Hunter, T. & Pawson, T. 1992 Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J. 11, 1365-1372.
-
(1992)
EMBO J.
, vol.11
, pp. 1365-1372
-
-
Reedijk, M.1
Liu, X.2
Van Der Geer, P.3
Letwin, K.4
Waterfield, M.D.5
Hunter, T.6
Pawson, T.7
-
98
-
-
0019790941
-
Phosphotyrosine containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten
-
Ross, A. H., Baltimore, D. & Eisen, H. 1981 Phosphotyrosine containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten. Nature 294, 654-656.
-
(1981)
Nature
, vol.294
, pp. 654-656
-
-
Ross, A.H.1
Baltimore, D.2
Eisen, H.3
-
99
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell, S. M. (and 11 others) 1995 Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science 270, 797-800.
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russell, S.M.1
-
101
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg-Buchholz, K., Fujiwara, Y., Gendron-Maguire, M., Gridley, T., Wolburg, H., Risau, W. & Qin, Y. 1995 Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376, 70-74.
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maguire, M.6
Gridley, T.7
Wolburg, H.8
Risau, W.9
Qin, Y.10
-
102
-
-
0028417436
-
Molecular cloning of a tyrosine kinase gene from the marine sponge Geodia cydonium: A new member belonging to the receptor tyrosine kinase class II family
-
Schacke, H., Schroder, H. G., Gamulin, V., Rinkevich, B., Muller, I. M. & Muller, W. E. 1994 Molecular cloning of a tyrosine kinase gene from the marine sponge Geodia cydonium: a new member belonging to the receptor tyrosine kinase class II family. Molec. Membr. Biol. 11, 101-107.
-
(1994)
Molec. Membr. Biol.
, vol.11
, pp. 101-107
-
-
Schacke, H.1
Schroder, H.G.2
Gamulin, V.3
Rinkevich, B.4
Muller, I.M.5
Muller, W.E.6
-
103
-
-
0029834447
-
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
-
Schlaepfer, D. D. & Hunter, T. 1996 Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases. Molec. Cell Biol. 16, 5623-5633.
-
(1996)
Molec. Cell Biol.
, vol.16
, pp. 5623-5633
-
-
Schlaepfer, D.D.1
Hunter, T.2
-
104
-
-
0030926774
-
Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src
-
Schlaepfer, D. D. & Hunter, T. 1997 Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src. J. Biol. Chem. 272, 13189-13195.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13189-13195
-
-
Schlaepfer, D.D.1
Hunter, T.2
-
105
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer, D. D., Hanks, S. K., Hunter, T. & van der Geer, P. 1994 Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372, 786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
107
-
-
0023024754
-
Allosteric regulation of the epidermal growth factor receptor kinase
-
Schlessinger, J. 1986 Allosteric regulation of the epidermal growth factor receptor kinase. J. Cell Biol. 103, 2067-2072.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2067-2072
-
-
Schlessinger, J.1
-
109
-
-
0019468487
-
Vinculin: A cytoskeletal substrate of the transforming protein of Rous sarcoma virus
-
Sefton, B. M., Hunter, T., Ball, E. H. & Singer, S. J. 1981a Vinculin: a cytoskeletal substrate of the transforming protein of Rous sarcoma virus. Cell 24, 165-174.
-
(1981)
Cell
, vol.24
, pp. 165-174
-
-
Sefton, B.M.1
Hunter, T.2
Ball, E.H.3
Singer, S.J.4
-
110
-
-
0018851827
-
Phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus
-
Sefton, B. M., Hunter, T., Beemon, K. & Eckhart, W. 1980 Phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus. Cell 20, 807-816.
-
(1980)
Cell
, vol.20
, pp. 807-816
-
-
Sefton, B.M.1
Hunter, T.2
Beemon, K.3
Eckhart, W.4
-
111
-
-
0019428315
-
Evidence that the Abelson virus protein functions in vivo as a protein kinase which phosphorylates tyrosine
-
Sefton, B. M., Hunter, T. & Raschke, W. C. 1981b Evidence that the Abelson virus protein functions in vivo as a protein kinase which phosphorylates tyrosine. Proc. Natn. Acad. Sci. USA 78, 1552-1556.
-
(1981)
Proc. Natn. Acad. Sci. USA
, vol.78
, pp. 1552-1556
-
-
Sefton, B.M.1
Hunter, T.2
Raschke, W.C.3
-
112
-
-
0030831104
-
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
-
Shalaby, F., Ho, J., Stanford, W. L., Fischer, K. D., Schuh, A. C., Schwartz, L., Bernstein, A. & Rossant, J. 1997 A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.
-
(1997)
Cell
, vol.89
, pp. 981-990
-
-
Shalaby, F.1
Ho, J.2
Stanford, W.L.3
Fischer, K.D.4
Schuh, A.C.5
Schwartz, L.6
Bernstein, A.7
Rossant, J.8
-
113
-
-
0027197067
-
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
-
Shultz, L. D., Schweitzer, P. A., Rajan, T. V., Yi, T., Ihle, J. N., Matthews, R. J., Thomas, M. L. & Beier, D. R. 1993 Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73, 1445-1454.
-
(1993)
Cell
, vol.73
, pp. 1445-1454
-
-
Shultz, L.D.1
Schweitzer, P.A.2
Rajan, T.V.3
Yi, T.4
Ihle, J.N.5
Matthews, R.J.6
Thomas, M.L.7
Beier, D.R.8
-
114
-
-
0021860692
-
v-src abolishes kinase activity, transformation, and tumorigenicity
-
v-src abolishes kinase activity, transformation, and tumorigenicity. Molec. Cell Biol. 5, 1772-1779.
-
(1985)
Molec. Cell Biol.
, vol.5
, pp. 1772-1779
-
-
Snyder, M.A.1
Bishop, J.M.2
McGraith, J.P.3
Levinson, A.D.4
-
115
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang, Z. (and 16 others) 1993 SH2 domains recognize specific phosphopeptide sequences. Cell 72, 767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
-
116
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
-
Songyang, Z. (and 13 others) 1995 Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373, 536-539.
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Songyang, Z.1
-
117
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., Montgomery, C., Geske, R. & Bradley, A. 1991 Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64, 693-702.
-
(1991)
Cell
, vol.64
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
118
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMACl, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck, P. A. (and 14 others) 1997 Identification of a candidate tumour suppressor gene, MMACl, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15, 356-362.
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
-
119
-
-
0027970874
-
Protein-tyrosine phosphatases
-
Stone, R. L. & Dixon, J. E. 1994 Protein-tyrosine phosphatases. J. Biol. Chem. 269, 31323-31326.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31323-31326
-
-
Stone, R.L.1
Dixon, J.E.2
-
120
-
-
0030005705
-
Protein tyrosine phosphatases in signaling
-
Streuli, M. 1996 Protein tyrosine phosphatases in signaling. Curr. Opin. Cell Biol. 8, 182-188.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 182-188
-
-
Streuli, M.1
-
121
-
-
0029991867
-
The WW module competes with the SH3 domain?
-
Sudol, M. 1996 The WW module competes with the SH3 domain? Trends Biochem. Sci. 21, 161-163.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 161-163
-
-
Sudol, M.1
-
122
-
-
0028149381
-
The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
-
Sun, H. & Tonks, N. K. 1994 The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends Biochem. Sci. 19, 480-485.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 480-485
-
-
Sun, H.1
Tonks, N.K.2
-
123
-
-
0025351476
-
Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum
-
Tan, J. L. & Spudich, J. A. 1990 Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum. Molec. Cell Biol. 10, 3578-3583.
-
(1990)
Molec. Cell Biol.
, vol.10
, pp. 3578-3583
-
-
Tan, J.L.1
Spudich, J.A.2
-
124
-
-
0026656320
-
Lilly Lecture: Molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene
-
Taylor, S. I. 1992 Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene. Diabetes 41, 1473-1490.
-
(1992)
Diabetes
, vol.41
, pp. 1473-1490
-
-
Taylor, S.I.1
-
125
-
-
0030348110
-
Protein tyrosine phosphatases and the control of cellular signaling responses
-
Tonks, N. K. 1996 Protein tyrosine phosphatases and the control of cellular signaling responses. Adv. Pharmacol. 36, 91-119.
-
(1996)
Adv. Pharmacol.
, vol.36
, pp. 91-119
-
-
Tonks, N.K.1
-
126
-
-
0023924803
-
Purification of the major protein-tyrosine-phosphatases of human placenta
-
Tonks, N. K., Diltz, G. D. & Fischer, E. H. 1988 Purification of the major protein-tyrosine-phosphatases of human placenta. J. Biol. Chem. 263, 6722-6730.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6722-6730
-
-
Tonks, N.K.1
Diltz, G.D.2
Fischer, E.H.3
-
127
-
-
0028933161
-
The receptor-like protein-tyrosine phosphatase, RPTPα, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane
-
Tracy, S., van der Geer, P. & Hunter, T. 1995 The receptor-like protein-tyrosine phosphatase, RPTPα, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane. J. Biol. Chem. 270, 10587-10594.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10587-10594
-
-
Tracy, S.1
Van Der Geer, P.2
Hunter, T.3
-
128
-
-
0027195626
-
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
-
Tsui, H. W., Siminovitch, K. A., de Souza, L. & Tsui, F. W. 1993 Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nat. Genet. 4, 124-129.
-
(1993)
Nat. Genet.
, vol.4
, pp. 124-129
-
-
Tsui, H.W.1
Siminovitch, K.A.2
De Souza, L.3
Tsui, F.W.4
-
129
-
-
0027399081
-
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
-
Tsukada, S. (and 13 others) 1993 Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 72, 279-290.
-
(1993)
Cell
, vol.72
, pp. 279-290
-
-
Tsukada, S.1
-
130
-
-
0028985934
-
Biotherapy of B-cell precursor leukaemia by targeting genistein to CD19-associated tyrosine kinases
-
Uckun, F. M., Evans, W. E., Forsyth, C. J., Waddick, K. G., Ahlgren, L. T., Chelstrom, L. M., Burkhardt, A., Bolen, J. & Myers, D. E. 1995 Biotherapy of B-cell precursor leukaemia by targeting genistein to CD19-associated tyrosine kinases. Science 267, 886-891.
-
(1995)
Science
, vol.267
, pp. 886-891
-
-
Uckun, F.M.1
Evans, W.E.2
Forsyth, C.J.3
Waddick, K.G.4
Ahlgren, L.T.5
Chelstrom, L.M.6
Burkhardt, A.7
Bolen, J.8
Myers, D.E.9
-
131
-
-
0019332971
-
Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes
-
Ushiro, H. & Cohen, S. 1980 Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. J. Biol. Chem. 255, 8363-8365.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 8363-8365
-
-
Ushiro, H.1
Cohen, S.2
-
132
-
-
0027211693
-
Phospholipase C-γl and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
-
Valius, M. & Kazlauskas, A. 1993 Phospholipase C-γl and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73, 321-334.
-
(1993)
Cell
, vol.73
, pp. 321-334
-
-
Valius, M.1
Kazlauskas, A.2
-
133
-
-
0030463433
-
Mitogenic signaling via G protein-coupled receptors
-
van Biesen, T., Luttrell, L. M., Hawes, B. E. & Lefkowitz, R. J. 1996 Mitogenic signaling via G protein-coupled receptors. Endocr. Rev. 17, 698-714.
-
(1996)
Endocr. Rev.
, vol.17
, pp. 698-714
-
-
Van Biesen, T.1
Luttrell, L.M.2
Hawes, B.E.3
Lefkowitz, R.J.4
-
134
-
-
0025289924
-
Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimuIated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line
-
van der Geer, P. & Hunter, T. 1990 Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimuIated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line. Molec. Cell Biol. 10, 2991-3002.
-
(1990)
Molec. Cell Biol.
, vol.10
, pp. 2991-3002
-
-
Van Der Geer, P.1
Hunter, T.2
-
135
-
-
0025778743
-
Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription
-
van der Geer, P. & Hunter, T. 1991 Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription. Molec. Cell Biol. 11, 4698-4709.
-
(1991)
Molec. Cell Biol.
, vol.11
, pp. 4698-4709
-
-
Van Der Geer, P.1
Hunter, T.2
-
136
-
-
0027375860
-
Mutation of Tyr697, a GRB2-binding site, and Tyr 721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts
-
van der Geer, P. & Hunter, T. 1993 Mutation of Tyr697, a GRB2-binding site, and Tyr 721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 12, 5161-5172.
-
(1993)
EMBO J.
, vol.12
, pp. 5161-5172
-
-
Van Der Geer, P.1
Hunter, T.2
-
137
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer, P., Hunter, T. & Lindberg, R. A. 1994 Receptor protein-tyrosine kinases and their signal transduction pathways. A. Rev. Cell Biol. 10, 251-337.
-
(1994)
A. Rev. Cell Biol.
, vol.10
, pp. 251-337
-
-
Van Der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
138
-
-
0028781009
-
One gene - Four syndromes
-
van Heyningen, V. 1994 One gene - four syndromes. Nature 367, 319-320.
-
(1994)
Nature
, vol.367
, pp. 319-320
-
-
Van Heyningen, V.1
-
139
-
-
0027441332
-
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
-
Vetrie, D. (and 11 others) 1993 The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature 361, 226-233.
-
(1993)
Nature
, vol.361
, pp. 226-233
-
-
Vetrie, D.1
-
140
-
-
0030460775
-
Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2
-
Vikkula, M. (and 11 others) 1996 Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 87, 1181-1190.
-
(1996)
Cell
, vol.87
, pp. 1181-1190
-
-
Vikkula, M.1
-
141
-
-
0027409064
-
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms
-
Waksman, G., Shoelson, S. E., Pant, N., Cowburn, D. & Kuriyan, J. 1993 Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell 72, 779-790.
-
(1993)
Cell
, vol.72
, pp. 779-790
-
-
Waksman, G.1
Shoelson, S.E.2
Pant, N.3
Cowburn, D.4
Kuriyan, J.5
-
142
-
-
0025998251
-
The receptor-like protein tyrosine phosphatase HPTPα has two active catalytic domains with distinct substrate specificities
-
Wang, Y. & Fallen, G. J. 1991 The receptor-like protein tyrosine phosphatase HPTPα has two active catalytic domains with distinct substrate specificities. EMBO J. 10, 3231-3237.
-
(1991)
EMBO J.
, vol.10
, pp. 3231-3237
-
-
Wang, Y.1
Fallen, G.J.2
-
143
-
-
0031005778
-
FGFR activation in skeletal disorders: Too much of a good thing
-
Webster, M. K. & Donoghue, D. J. 1997 FGFR activation in skeletal disorders: too much of a good thing. Trends Genet. 13, 178-182.
-
(1997)
Trends Genet.
, vol.13
, pp. 178-182
-
-
Webster, M.K.1
Donoghue, D.J.2
-
144
-
-
0029855280
-
Interaction between Gabi and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis
-
Weidner, K. M., Di Cesare, S., Sachs, M., Brinkmann, V., Behrens, J. & Birchmeier, W. 1996 Interaction between Gabi and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature 384, 173-176.
-
(1996)
Nature
, vol.384
, pp. 173-176
-
-
Weidner, K.M.1
Di Cesare, S.2
Sachs, M.3
Brinkmann, V.4
Behrens, J.5
Birchmeier, W.6
-
145
-
-
0028157728
-
The IRS-1 signaling system
-
White, M. F. 1994 The IRS-1 signaling system. Curr. Opin. Gen. Dev. 4, 47-54.
-
(1994)
Curr. Opin. Gen. Dev.
, vol.4
, pp. 47-54
-
-
White, M.F.1
-
146
-
-
0027715423
-
Mode-switching of a voltage-gated cation channel is mediated by a protein kinase A-regulated tyrosine phosphatase
-
Wilson, G. F. & Kaczmarek, L. K. 1993 Mode-switching of a voltage-gated cation channel is mediated by a protein kinase A-regulated tyrosine phosphatase. Nature 366, 433-438.
-
(1993)
Nature
, vol.366
, pp. 433-438
-
-
Wilson, G.F.1
Kaczmarek, L.K.2
-
147
-
-
0018905242
-
Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine
-
Witte, O. N., Dasgupta, A. & Baltimore, D. 1980 Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine. Nature 283, 826-831.
-
(1980)
Nature
, vol.283
, pp. 826-831
-
-
Witte, O.N.1
Dasgupta, A.2
Baltimore, D.3
-
148
-
-
0031025991
-
Three-dimensional structure of the tyrosine kinase c-Src
-
Xu, W., Harrison, S. C. & Eck, M. J. 1997 Three-dimensional structure of the tyrosine kinase c-Src. Nature 385, 595-602.
-
(1997)
Nature
, vol.385
, pp. 595-602
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
149
-
-
0031444245
-
Identification of the Abl- And rasGAP-associated 62 kDa protein as a docking protein, Dok
-
Yamanashi, Y. & Baltimore, D. 1997 Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell 88, 205-211.
-
(1997)
Cell
, vol.88
, pp. 205-211
-
-
Yamanashi, Y.1
Baltimore, D.2
-
150
-
-
0031053363
-
NMDA channel regulation by channel-associated protein tyrosine kinase Src
-
Yu, X. M., Askalan, R., Keil, G. J. & Salter, M. W. 1997 NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science 275, 674-678.
-
(1997)
Science
, vol.275
, pp. 674-678
-
-
Yu, X.M.1
Askalan, R.2
Keil, G.J.3
Salter, M.W.4
|