Post-injury delivery of rAAV2-CNTF combined with short-term pharmacotherapy is neuroprotective and promotes extensive axonal regeneration after optic nerve trauma

Journal of Neurotrauma

Volumn 28, Issue 12, 2011, Pages 2475-2483

  Hellström, Mats ^a   Pollett, Margaret A ^a   Harvey, Alan R ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

cAMP; ciliary neurotrophic factor; growth factors; neural injury; RGC; therapeutic approaches for the treatment of CNS injury; viral mediated transfection

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; ADENOVIRUS VECTOR; FLUOROGOLD; GREEN FLUORESCENT PROTEIN; PEPROTECH; RECOMBINANT CILIARY NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG POTENTIATION; FEMALE; GENE EXPRESSION; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE FIBER TRANSECTION; NERVE GRAFT; NONHUMAN; OPTIC NERVE INJURY; RAT; RETINA GANGLION CELL; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; AXONS; CILIARY NEUROTROPHIC FACTOR; CYCLIC AMP; DEPENDOVIRUS; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; NERVE REGENERATION; OPTIC NERVE INJURIES; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; TIME FACTORS;

EID: 83455213993     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.1928     Document Type: Article

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