AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse

Molecular Therapy

Volumn 3, Issue 2, 2001, Pages 241-248

  Liang, Fong Qi ^a   Dejneka, Nadine S ^a   Cohen, Daniel R ^a   Krasnoperova, Natalia V ^b   Lem, Janis ^b   Maguire, Albert M ^a   Dudus, Lorita ^c   Fisher, Krishna J ^c   Bennett, Jean ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NEW ENGLAND EYE CENTER   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AAV; Apoptosis; CNTF; Gene therapy; Neurotrophic factor; Photoreceptor; Retinal degeneration

Indexed keywords

BIOCHEMICAL MARKER; CILIARY NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEIN; RHODOPSIN; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL TYPE; CHICK EMBRYO; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NERVE CELL; NONHUMAN; PHOTORECEPTOR; PRESERVATION; RETINA DEGENERATION; RETINITIS PIGMENTOSA; SPINAL GANGLION; VISUAL IMPAIRMENT;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE; ANIMALIA;

EID: 0034980737     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0252     Document Type: Article

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