Self-complementary AAV5 vector facilitates quicker transgene expression in photoreceptor and retinal pigment epithelial cells of normal mouse

Experimental Eye Research

Volumn 90, Issue 5, 2010, Pages 546-554

  Kong, Fansheng ^a   Li, Wensheng ^a   Li, Xia ^a   Zheng, Qinxiang ^a   Dai, Xufeng ^a   Zhou, Xiangtian ^a   Boye, Sanford L ^b   Hauswirth, William W ^b   Qu, Jia ^a   Pang, Ji jing ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

AAV5; Intravitreal injection; Photoreceptor; RPE; ScAAV5; Self complementary AAV; Subretinal injection; Transgene expression

Indexed keywords

GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; DISEASE MODEL; ENUCLEATION; FLUORESCENCE MICROSCOPY; FROZEN SECTION; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; MEDICAL RESEARCH; MOUSE; NONHUMAN; PHOTORECEPTOR CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DYSTROPHY; RETINITIS PIGMENTOSA; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE; ANIMAL; C57BL MOUSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; INJECTION; METABOLISM; PHYSIOLOGY; RETINA; VITREOUS BODY;

ANIMALS; DEPENDOVIRUS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; INJECTIONS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RETINAL PIGMENT EPITHELIUM; TRANSGENES; VITREOUS BODY;

EID: 77951235115     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2010.01.011     Document Type: Article

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