Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons

Molecular and Cellular Neuroscience

Volumn 46, Issue 2, 2011, Pages 507-515

  Hellstrom M ^a   Muhling, J ^a   Ehlert, E M ^b   Verhaagen, J ^b,c   Pollett, M A ^a   Hu, Y ^a,d   Harvey, A R ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Adeno associated viral vectors; Axonal regeneration; Cytokines; Growth inhibition; Peripheral nerve graft; SOCS

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYCLIC AMP; CYTOKINE; MESSENGER RNA; RECOMBINANT CILIARY NEUROTROPHIC FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL REGENERATION; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE GRAFT; NONHUMAN; OPTIC NERVE; PKA; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; SUTURE; UPREGULATION; VITREOUS BODY;

ADENOVIRIDAE; ANIMALS; AXONS; CILIARY NEUROTROPHIC FACTOR; CYCLIC AMP; FEMALE; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; INTRAVITREAL INJECTIONS; MICROSCOPY, CONFOCAL; NERVE REGENERATION; NEUROPROTECTIVE AGENTS; OPTIC NERVE INJURIES; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; RETINAL GANGLION CELLS; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSDUCTION, GENETIC;

RATTUS;

EID: 78751701950     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2010.12.003     Document Type: Article

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