Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transfer

Molecular Therapy

Volumn 11, Issue 3, 2005, Pages 373-381

  Malik, J M I ^a   Shevtsova, Z ^a   Bahr M ^a   Kügler, Sebastian ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

AAV vectors; Axotomy; Bcl XL; Mitochondria; Neurodegeneration; Retinal ganglion cells

Indexed keywords

GREEN FLUORESCENT PROTEIN; NEUROTROPHIN; PARVOVIRUS VECTOR; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; IN VIVO STUDY; LONG TERM CARE; MITOCHONDRIAL MEMBRANE; NERVE CELL; NERVE DEGENERATION; NERVE FIBER TRANSECTION; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; RAT; RETINA GANGLION CELL; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; AXOTOMY; BCL-X PROTEIN; CENTRAL NERVOUS SYSTEM DISEASES; DEPENDOVIRUS; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; NEURODEGENERATIVE DISEASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RETINAL GANGLION CELLS; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS 2;

EID: 14044260099     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.11.014     Document Type: Article

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