-
1
-
-
0037029424
-
Multiple sclerosis
-
DOI 10.1016/S0140-6736(02)08220-X
-
Compston A, Coles A. Multiple sclerosis. Lancet 2002; 359 (9313): 1221-31 (Pubitemid 34304266)
-
(2002)
Lancet
, vol.359
, Issue.9313
, pp. 1221-1231
-
-
Compston, A.1
Coles, A.2
-
2
-
-
33746588738
-
The epidemiology of multiple sclerosis in Europe
-
DOI 10.1111/j.1468-1331.2006.01342.x
-
Pugliatti M, Rosati G, Carton H, et al. The epidemiology of multiple sclerosis in Europe. Eur J Neurol 2006; 13 (7): 700-22 (Pubitemid 44143944)
-
(2006)
European Journal of Neurology
, vol.13
, Issue.7
, pp. 700-722
-
-
Pugliatti, M.1
Rosati, G.2
Carton, H.3
Riise, T.4
Drulovic, J.5
Vecsei, L.6
Milanov, I.7
-
3
-
-
33644974688
-
Secondary progressive multiple sclerosis: Current knowledge and future challenges
-
Rovaris M, Confavreux C, Furlan R, et al. Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol 2006; 5 (4): 343-54
-
(2006)
Lancet Neurol
, vol.5
, Issue.4
, pp. 343-54
-
-
Rovaris, M.1
Confavreux, C.2
Furlan, R.3
-
4
-
-
34548633861
-
Primary-progressive multiple sclerosis
-
DOI 10.1016/S1474-4422(07)70243-0, PII S1474442207702430
-
Miller DH, Leary SM. Primary-progressive multiple sclerosis. Lancet Neurol 2007; 6 (10): 903-12 (Pubitemid 47405002)
-
(2007)
Lancet Neurology
, vol.6
, Issue.10
, pp. 903-912
-
-
Miller, D.H.1
Leary, S.M.2
-
5
-
-
61949261269
-
Management strategies for improving the tolerability of interferons in the treatment of multiple sclerosis
-
Girouard N, Theoret G. Management strategies for improving the tolerability of interferons in the treatment of multiple sclerosis. Can J Neurosci Nurs 2008; 30 (4): 18-25
-
(2008)
Can J Neurosci Nurs
, vol.30
, Issue.4
, pp. 18-25
-
-
Girouard, N.1
Theoret, G.2
-
6
-
-
0037435526
-
Interferon β-1a in primary progressive MS: An exploratory, randomized, controlled trial
-
Leary SM, Miller DH, Stevenson VL, et al. Interferon beta-1a in primary progressive MS: an exploratory, randomized, controlled trial. Neurology 2003; 60 (1): 44-51 (Pubitemid 36070642)
-
(2003)
Neurology
, vol.60
, Issue.1
, pp. 44-51
-
-
Leary, S.M.1
Miller, D.H.2
Stevenson, V.L.3
Brex, P.A.4
Chard, D.T.5
Thompson, A.J.6
-
7
-
-
3042555134
-
Overview of European pilot study of interferon beta-1b in primary progressive multiple sclerosis
-
discussion 62-4
-
Montalban X. Overview of European pilot study of interferon beta-1b in primary progressive multiple sclerosis. Mult Scler 2004; 10 Suppl. 1: S62; discussion 62-4
-
(2004)
Mult Scler
, vol.10
, Issue.SUPPL. 1
-
-
Montalban, X.1
-
8
-
-
70349781937
-
Glatiramer acetate treatment in PPMS: Why males appear to respond favorably
-
Wolinsky JS, Shochat T, Weiss S, et al. Glatiramer acetate treatment in PPMS: why males appear to respond favorably. J Neurol Sci 2009; 286 (1-2): 92-8
-
(2009)
J Neurol Sci
, vol.286
, Issue.1-2
, pp. 92-8
-
-
Wolinsky, J.S.1
Shochat, T.2
Weiss, S.3
-
9
-
-
3042601982
-
The PROMiSe trial: Baseline data review and progress report
-
discussion S71-2
-
Wolinsky JS. The PROMiSe trial: baseline data review and progress report. Mult Scler 2004; 10 Suppl. 1: S65-71; discussion S71-2
-
(2004)
Mult Scler
, vol.10
, Issue.SUPPL. 1
-
-
Wolinsky, J.S.1
-
10
-
-
0037056364
-
Benefit of interferon beta-1a on MSFC progression in secondary progressive MS
-
Cohen JA, Cutter GR, Fischer JS, et al. Benefit of interferon beta-1a on MSFC progression in secondary progressive MS. Neurology 2002; 59 (5): 679-87
-
(2002)
Neurology
, vol.59
, Issue.5
, pp. 679-87
-
-
Cohen, J.A.1
Cutter, G.R.2
Fischer, J.S.3
-
11
-
-
0035849496
-
Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results
-
Randomized controlled trial of interferon-beta-1a in secondary progressive MS: clinical results. Neurology 2001; 56 (11): 1496-504
-
(2001)
Neurology
, vol.56
, Issue.11
, pp. 1496-504
-
-
-
12
-
-
8844222623
-
Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study
-
Panitch H, Miller A, Paty D, et al. Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study. Neurology 2004; 63 (10): 1788-95 (Pubitemid 39532370)
-
(2004)
Neurology
, vol.63
, Issue.10
, pp. 1788-1795
-
-
Panitch, H.1
-
13
-
-
0001353603
-
European Study Group on interferon beta-1b in secondary progressive MS: Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis
-
European Study Group on interferon beta-1b in secondary progressive MS: placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. Lancet 1998; 352 (9139): 1491-7
-
(1998)
Lancet
, vol.352
, Issue.9139
, pp. 1491-7
-
-
-
14
-
-
52649102501
-
Antibody engineering principles and applications
-
Loo L, Robinson MK, Adams GP. Antibody engineering principles and applications. Cancer J 2008; 14 (3): 149-53
-
(2008)
Cancer J
, vol.14
, Issue.3
, pp. 149-53
-
-
Loo, L.1
Robinson, M.K.2
Adams, G.P.3
-
15
-
-
65949120204
-
Hypersensitivity reactions to last generation chimeric, humanized [correction of umanized] and human recombinant monoclonal antibodies for therapeutic use
-
Calogiuri G, Ventura MT, Mason L, et al. Hypersensitivity reactions to last generation chimeric, humanized [correction of umanized] and human recombinant monoclonal antibodies for therapeutic use. Curr Pharm Des 2008; 14 (27): 2883-91
-
(2008)
Curr Pharm des
, vol.14
, Issue.27
, pp. 2883-91
-
-
Calogiuri, G.1
Ventura, M.T.2
Mason, L.3
-
16
-
-
48949092246
-
Development and characterization of mouse hybridomas
-
Mechetner E. Development and characterization of mouse hybridomas. Methods Mol Biol 2007; 378: 1-13
-
(2007)
Methods Mol Biol
, vol.378
, pp. 1-13
-
-
Mechetner, E.1
-
17
-
-
33746778816
-
Drug insight: Using monoclonal antibodies to treat multiple sclerosis
-
Hohlfeld R, Wekerle H. Drug insight: using monoclonal antibodies to treat multiple sclerosis. Nat Clin Pract Neurol 2005; 1 (1): 34-44
-
(2005)
Nat Clin Pract Neurol
, vol.1
, Issue.1
, pp. 34-44
-
-
Hohlfeld, R.1
Wekerle, H.2
-
19
-
-
19744382139
-
Rituximab-responsive CIDP [letter]
-
Briani C, Zara G, Zambello R, et al. Rituximab-responsive CIDP [letter]. Eur J Neurol 2004; 11 (11): 788
-
(2004)
Eur J Neurol
, vol.11
, Issue.11
, pp. 788
-
-
Briani, C.1
Zara, G.2
Zambello, R.3
-
20
-
-
22344452892
-
Treatment of immune-mediated, dysimmune neuropathies
-
DOI 10.1111/j.1600-0404.2005.00448.x
-
Finsterer J. Treatment of immune-mediated, dysimmune neuropathies. Acta Neurol Scand 2005; 112 (2): 115-25 (Pubitemid 41003372)
-
(2005)
Acta Neurologica Scandinavica
, vol.112
, Issue.2
, pp. 115-125
-
-
Finsterer, J.1
-
21
-
-
33744921114
-
Rituximab therapy in monoclonal IgM-related neuropathies
-
DOI 10.1080/14786410500441664, PII G939300427167
-
Kilidireas C, Anagnostopoulos A, Karandreas N, et al. Rituximab therapy in monoclonal IgM-related neuropathies. Leuk Lymphoma 2006; 47 (5): 859-64 (Pubitemid 43840641)
-
(2006)
Leukemia and Lymphoma
, vol.47
, Issue.5
, pp. 859-864
-
-
Kilidireas, C.1
Anagnostopoulos, A.2
Karandreas, N.3
Mouselimi, L.4
Dimopoulos, M.-A.5
-
22
-
-
33846018016
-
Rituximab treatment in patients with IVIg-dependent immune polyneuropathy: A prospective pilot trial
-
DOI 10.1002/mus.20664
-
Gorson KC, Natarajan N, Ropper AH, et al. Rituximab treatment in patients with IVIg-dependent immune polyneuropathy: a prospective pilot trial. Muscle Nerve 2007; 35 (1): 66-9 (Pubitemid 46052650)
-
(2007)
Muscle and Nerve
, vol.35
, Issue.1
, pp. 66-69
-
-
Gorson, K.C.1
Natarajan, N.2
Ropper, A.H.3
Weinstein, R.4
-
23
-
-
16844364342
-
Immunologic and clinical responses to rituximab in a child with opsoclonus-myoclonus syndrome
-
DOI 10.1542/peds.2004-0845
-
Pranzatelli MR, Tate ED, Travelstead AL, et al. Immunologic and clinical responses to rituximab in a child with opsoclonus-myoclonus syndrome. Pediatrics 2005; 115 (1): e115-9 (Pubitemid 43046272)
-
(2005)
Pediatrics
, vol.115
, Issue.1
-
-
Pranzatelli, M.R.1
Tate, E.D.2
Travelstead, A.L.3
Longee, D.4
-
24
-
-
38549143161
-
Rituximab for treatment of Opsoclonus-myoclonus syndrome in neuroblastoma
-
DOI 10.1002/pbc.21009
-
Burke MJ, Cohn SL. Rituximab for treatment of opsoclonus-myoclonus syndrome in neuroblastoma. Pediatr Blood Cancer 2008; 50 (3): 679-80 (Pubitemid 351155858)
-
(2008)
Pediatric Blood and Cancer
, vol.50
, Issue.3
, pp. 679-680
-
-
Burke, M.J.1
Cohn, S.L.2
-
25
-
-
33749358285
-
Rituximab (anti-CD20) adjunctive therapy for Opsoclonus-Myoclonus syndrome
-
DOI 10.1097/01.mph.0000212991.64435.f0, PII 0004342620060900000008
-
Pranzatelli MR, Tate ED, Travelstead AL, et al. Rituximab (anti-CD20) adjunctive therapy for opsoclonusmyoclonus syndrome. J Pediatr Hematol Oncol 2006; 28 (9): 585-93 (Pubitemid 44496336)
-
(2006)
Journal of Pediatric Hematology/Oncology
, vol.28
, Issue.9
, pp. 585-593
-
-
Pranzatelli, M.R.1
Tate, E.D.2
Travelstead, A.L.3
Barbosa, J.4
Bergamini, R.A.5
Civitello, L.6
Franz, D.N.7
Greffe, B.S.8
Hanson, R.D.9
Hurwitz, C.A.10
Kalinyak, K.A.11
Kelfer, H.12
Khakoo, Y.13
Mantovani, J.F.14
Nicholson, S.H.15
Sanders, J.M.16
Wegner, S.17
-
26
-
-
38549108981
-
Treatment of neuroblastoma-related opsoclonus-myoclonus-ataxia syndrome with high-dose dexamethasone pulses
-
DOI 10.1002/pbc.21107
-
Ertle F, Behnisch W, Al Mulla NA, et al. Treatment of neuroblastoma-related opsoclonus-myoclonus-ataxia syndrome with high-dose dexamethasone pulses. Pediatr Blood Cancer 2008; 50 (3): 683-7 (Pubitemid 351155860)
-
(2008)
Pediatric Blood and Cancer
, vol.50
, Issue.3
, pp. 683-687
-
-
Ertle, F.1
Behnisch, W.2
Al Mulla, N.A.3
Bessisso, M.4
Rating, D.5
Mechtersheimer, G.6
Hero, B.7
Kulozik, A.E.8
-
27
-
-
49749087581
-
Rituximab and intravenous immunoglobulins for relapsing postinfectious opsoclonus-myoclonus syndrome
-
Leen WG, Weemaes CM, Verbeek MM, et al. Rituximab and intravenous immunoglobulins for relapsing postinfectious opsoclonus-myoclonus syndrome. Pediatr Neurol 2008; 39 (3): 213-7
-
(2008)
Pediatr Neurol
, vol.39
, Issue.3
, pp. 213-7
-
-
Leen, W.G.1
Weemaes, C.M.2
Verbeek, M.M.3
-
28
-
-
57449102205
-
Response to rituximab and prednisolone for opsoclonus-myoclonusataxia syndrome in a child with ganglioneuroblastoma
-
Corapcioglu F, Mutlu H, Kara B, et al. Response to rituximab and prednisolone for opsoclonus-myoclonusataxia syndrome in a child with ganglioneuroblastoma. Pediatr Hematol Oncol 2008; 25 (8): 756-61
-
(2008)
Pediatr Hematol Oncol
, vol.25
, Issue.8
, pp. 756-61
-
-
Corapcioglu, F.1
Mutlu, H.2
Kara, B.3
-
29
-
-
77249095007
-
Long-term cerebrospinal fluid and blood lymphocyte dynamics after rituximab for pediatric opsoclonus-myoclonus
-
Pranzatelli MR, Tate ED, Travelstead AL, et al. Long-term cerebrospinal fluid and blood lymphocyte dynamics after rituximab for pediatric opsoclonus-myoclonus. J Clin Immunol 2010; 30 (1): 106-13
-
(2010)
J Clin Immunol
, vol.30
, Issue.1
, pp. 106-13
-
-
Pranzatelli, M.R.1
Tate, E.D.2
Travelstead, A.L.3
-
30
-
-
77649134992
-
B cell depletion therapy for new-onset opsoclonus-myoclonus
-
Pranzatelli MR, Tate ED, Swan JA, et al. B cell depletion therapy for new-onset opsoclonus-myoclonus. Mov Disord 2010; 25 (2): 238-42
-
(2010)
Mov Disord
, vol.25
, Issue.2
, pp. 238-42
-
-
Pranzatelli, M.R.1
Tate, E.D.2
Swan, J.A.3
-
31
-
-
77955907835
-
Pediatric dosing of rituximab revisited: Serum concentrations in opsoclonus-myoclonus syndrome
-
Pranzatelli MR, Tate ED, Verhulst SJ, et al. Pediatric dosing of rituximab revisited: serum concentrations in opsoclonus-myoclonus syndrome. J Pediatr Hematol Oncol 2010; 32 (5): e167-72
-
(2010)
J Pediatr Hematol Oncol
, vol.32
, Issue.5
-
-
Pranzatelli, M.R.1
Tate, E.D.2
Verhulst, S.J.3
-
32
-
-
37549034676
-
Response to rituximab in a child with neuroblastoma and opsoclonus-myoclonus
-
Bell J, Moran C, Blatt J. Response to rituximab in a child with neuroblastoma and opsoclonus-myoclonus. Pediatr Blood Cancer 2008; 50 (2): 370-1
-
(2008)
Pediatr Blood Cancer
, vol.50
, Issue.2
, pp. 370-1
-
-
Bell, J.1
Moran, C.2
Blatt, J.3
-
33
-
-
34347264888
-
Complete remission induced by rituximab in refractory, seronegative, muscle-specific, kinase-positive myasthenia gravis [2]
-
DOI 10.1136/jnnp.2006.093567
-
Baek WS, BasheyA, SheeanGL. Complete remission induced by rituximab in refractory, seronegative, muscle-specific, kinase-positive myasthenia gravis [letter]. J Neurol Neurosurg Psychiatry 2007; 78 (7): 771 (Pubitemid 46998860)
-
(2007)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.78
, Issue.7
, pp. 771
-
-
Baek, W.S.1
Bashey, A.2
Sheean, G.L.3
-
34
-
-
77649159695
-
Rituximab in the management of refractory myasthenia gravis
-
Zebardast N, Patwa HS, Novella SP, et al. Rituximab in the management of refractory myasthenia gravis. Muscle Nerve 2010; 41 (3): 375-8
-
(2010)
Muscle Nerve
, vol.41
, Issue.3
, pp. 375-8
-
-
Zebardast, N.1
Patwa, H.S.2
Novella, S.P.3
-
35
-
-
77956418989
-
Rituximab for severe myasthenia gravis: Experience from five patients
-
Lindberg C, Bokarewa M. Rituximab for severe myasthenia gravis: experience from five patients. Acta Neurol Scand 2010; 122 (4): 225-8
-
(2010)
Acta Neurol Scand
, vol.122
, Issue.4
, pp. 225-8
-
-
Lindberg, C.1
Bokarewa, M.2
-
36
-
-
79955754602
-
The use of rituximab in myasthenia gravis and Lambert-Eaton myasthenic syndrome
-
Maddison P, McConville J, Farrugia ME, et al. The use of rituximab in myasthenia gravis and Lambert-Eaton myasthenic syndrome. J Neurol Neurosurg Psychiatry 2010; 82 (6): 671-3
-
(2010)
J Neurol Neurosurg Psychiatry
, vol.82
, Issue.6
, pp. 671-3
-
-
Maddison, P.1
McConville, J.2
Farrugia, M.E.3
-
37
-
-
33645328823
-
Successful treatment of MuSK antibody-positive myasthenia gravis with rituximab
-
Hain B, Jordan K, Deschauer M, et al. Successful treatment of MuSK antibody-positive myasthenia gravis with rituximab. Muscle Nerve 2006; 33 (4): 575-80
-
(2006)
Muscle Nerve
, vol.33
, Issue.4
, pp. 575-80
-
-
Hain, B.1
Jordan, K.2
Deschauer, M.3
-
38
-
-
16844366404
-
An open label study of the effects of rituximab in neuromyelitis optica
-
Cree BA, Lamb S, Morgan K, et al. An open label study of the effects of rituximab in neuromyelitis optica. Neurology 2005; 64 (7): 1270-2
-
(2005)
Neurology
, vol.64
, Issue.7
, pp. 1270-2
-
-
Cree, B.A.1
Lamb, S.2
Morgan, K.3
-
39
-
-
34547936733
-
Variable responses to rituximab treatment in neuromyelitis optica (Devic's disease)
-
DOI 10.1007/s10072-007-0823-z
-
Capobianco M, Malucchi S, di Sapio A, et al. Variable responses to rituximab treatment in neuromyelitis optica (Devic's disease). Neurol Sci 2007; 28 (4): 209-11 (Pubitemid 47263843)
-
(2007)
Neurological Sciences
, vol.28
, Issue.4
, pp. 209-211
-
-
Capobianco, M.1
Malucchi, S.2
Di Sapio, A.3
Gilli, F.4
Sala, A.5
Bottero, R.6
Marnetto, F.7
Doriguzzi Bozzo, C.8
Bertolotto, A.9
-
40
-
-
55949127730
-
Treatment of neuromyelitis optica with rituximab: Retrospective analysis of 25 patients
-
Jacob A, Weinshenker BG, Violich I, et al. Treatment of neuromyelitis optica with rituximab: retrospective analysis of 25 patients. Arch Neurol 2008; 65 (11): 1443-8
-
(2008)
Arch Neurol
, vol.65
, Issue.11
, pp. 1443-8
-
-
Jacob, A.1
Weinshenker, B.G.2
Violich, I.3
-
41
-
-
21344443453
-
Treatment of stiff person syndrome with rituximab
-
DOI 10.1136/jnnp.2004.051144
-
Baker MR, Das M, Isaacs J, et al. Treatment of stiff person syndrome with rituximab. J Neurol Neurosurg Psychiatry 2005; 76 (7): 999-1001 (Pubitemid 40909562)
-
(2005)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.76
, Issue.7
, pp. 999-1001
-
-
Baker, M.R.1
Das, M.2
Isaacs, J.3
Fawcett, P.R.W.4
Bates, D.5
-
42
-
-
69949186255
-
Monozygotic twins with stiff person syndrome and autoimmune thyroiditis: Rituximab inefficacy in a double-blind, randomised, placebo controlled crossover study
-
Venhoff N, Rizzi M, Salzer U, et al. Monozygotic twins with stiff person syndrome and autoimmune thyroiditis: rituximab inefficacy in a double-blind, randomised, placebo controlled crossover study. Ann Rheum Dis 2009; 68 (9): 1506-8
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.9
, pp. 1506-8
-
-
Venhoff, N.1
Rizzi, M.2
Salzer, U.3
-
43
-
-
75349086824
-
Rituximab treatment of stiff-person syndrome in a patient with thymoma, diabetes mellitus and autoimmune thyroiditis
-
Dupond JL, Essalmi L, Gil H, et al. Rituximab treatment of stiff-person syndrome in a patient with thymoma, diabetes mellitus and autoimmune thyroiditis. J Clin Neurosci 2010; 17 (3): 389-91
-
(2010)
J Clin Neurosci
, vol.17
, Issue.3
, pp. 389-91
-
-
Dupond, J.L.1
Essalmi, L.2
Gil, H.3
-
44
-
-
77749245795
-
Successful treatment with rituximab in a patient with stiff-person syndrome complicated by dysthyroid ophthalmopathy
-
Katoh N, Matsuda M, Ishii W, et al. Successful treatment with rituximab in a patient with stiff-person syndrome complicated by dysthyroid ophthalmopathy. Intern Med 2010; 49 (3): 237-41
-
(2010)
Intern Med
, vol.49
, Issue.3
, pp. 237-41
-
-
Katoh, N.1
Matsuda, M.2
Ishii, W.3
-
45
-
-
77955229461
-
Stiff-person syndrome: Persistent elevation of glutamic acid decarboxylase antibodies despite successful treatment with rituximab
-
Bacorro EA, Tehrani R. Stiff-person syndrome: persistent elevation of glutamic acid decarboxylase antibodies despite successful treatment with rituximab. J Clin Rheumatol 2010; 16 (5): 237-9
-
(2010)
J Clin Rheumatol
, vol.16
, Issue.5
, pp. 237-9
-
-
Bacorro, E.A.1
Tehrani, R.2
-
46
-
-
67649399221
-
Effect of alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis
-
Dalakas MC, Rakocevic G, Schmidt J, et al. Effect of alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis. Brain 2009; 132 (Pt 6): 1536-44
-
(2009)
Brain
, vol.132
, Issue.PART 6
, pp. 1536-44
-
-
Dalakas, M.C.1
Rakocevic, G.2
Schmidt, J.3
-
47
-
-
34250779802
-
Natalizumab for multiple sclerosis
-
DOI 10.1056/NEJMct071462
-
Ransohoff RM. Natalizumab for multiple sclerosis. NEngl J Med 2007; 356 (25): 2622-9 (Pubitemid 46961007)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.25
, pp. 2622-2629
-
-
Ransohoff, R.M.1
-
48
-
-
0027237424
-
α4β7 Integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
-
DOI 10.1016/0092-8674(93)90305-A
-
Berlin C, Berg EL, Briskin MJ, et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993; 74 (1): 185-95 (Pubitemid 23219889)
-
(1993)
Cell
, vol.74
, Issue.1
, pp. 185-195
-
-
Berlin, C.1
Berg, E.L.2
Briskin, M.J.3
Andrew, D.P.4
Kilshaw, P.J.5
Holzmann, B.6
Weissman, I.L.7
Hamann, A.8
Butcher, E.C.9
-
49
-
-
3042739652
-
4-integrin antagonist selective adhesion molecule inhibitors for MS
-
DOI 10.1586/14737175.4.4.571
-
Rudick RA, Sandrock A. Natalizumab: alpha 4-integrin antagonist selective adhesion molecule inhibitors for MS. Expert Rev Neurother 2004; 4 (4): 571-80 (Pubitemid 38890585)
-
(2004)
Expert Review of Neurotherapeutics
, vol.4
, Issue.4
, pp. 571-580
-
-
Rudick, R.A.1
Sandrock, A.2
-
50
-
-
61449227381
-
Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab
-
del PilarMM, Cravens PD, Winger R, et al. Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab. Arch Neurol 2008; 65 (12): 1596-603
-
(2008)
Arch Neurol
, vol.65
, Issue.12
, pp. 1596-603
-
-
Del Pilar, M.M.1
Cravens, P.D.2
Winger, R.3
-
51
-
-
20844454381
-
Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab
-
DOI 10.1038/nrd1752
-
Steinman L. Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab. Nat Rev Drug Discov 2005; 4 (6): 510-8 (Pubitemid 40861993)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.6
, pp. 510-518
-
-
Steinman, L.1
-
52
-
-
33646347357
-
Natalizumab effects on immune cell responses in multiple sclerosis
-
DOI 10.1002/ana.20859
-
Niino M, Bodner C, Simard ML, et al. Natalizumab effects on immune cell responses in multiple sclerosis. Ann Neurol 2006; 59 (5): 748-54 (Pubitemid 43673152)
-
(2006)
Annals of Neurology
, vol.59
, Issue.5
, pp. 748-754
-
-
Niino, M.1
Bodner, C.2
Simard, M.-L.3
Alatab, S.4
Gano, D.5
Kim, H.J.6
Trigueiro, M.7
Racicot, D.8
Guerette, C.9
Antel, J.P.10
Fournier, A.11
Grand'Maison, F.12
Bar-Or, A.13
-
53
-
-
0030694439
-
Anti-α4 integrin antibody induces apoptosis in murine thymocytes and staphylococcal enterotoxin B-activated lymph node T cells
-
Tchilian EZ, Owen JJ, Jenkinson EJ. Anti-alpha 4 integrin antibody induces apoptosis in murine thymocytes and staphylococcal enterotoxin B-activated lymph node T cells. Immunology 1997; 92 (3): 321-7 (Pubitemid 27488142)
-
(1997)
Immunology
, vol.92
, Issue.3
, pp. 321-327
-
-
Tchilian, E.Z.1
Owen, J.J.T.2
Jenkinson, E.J.3
-
54
-
-
39849089879
-
Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients
-
Lindberg RL, Achtnichts L, Hoffmann F, et al. Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients. J Neuroimmunol 2008; 194 (1-2): 153-64
-
(2008)
J Neuroimmunol
, vol.194
, Issue.1-2
, pp. 153-64
-
-
Lindberg, R.L.1
Achtnichts, L.2
Hoffmann, F.3
-
55
-
-
64149087952
-
Alpha4-Integrin antagonism with natalizumab: Effects and adverse effects
-
Stuve O, Gold R, Chan A, et al. alpha4-Integrin antagonism with natalizumab: effects and adverse effects. J Neurol 2008; 255 Suppl. 6: 58-65
-
(2008)
J Neurol
, vol.255
, Issue.SUPPL. 6
, pp. 58-65
-
-
Stuve, O.1
Gold, R.2
Chan, A.3
-
56
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
Yednock TA, Cannon C, Fritz LC, et al. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992; 356 (6364): 63-6
-
(1992)
Nature
, vol.356
, Issue.6364
, pp. 63-6
-
-
Yednock, T.A.1
Cannon, C.2
Fritz, L.C.3
-
57
-
-
0033546663
-
The effect of anti-α4 integrin antibody on brain lesion activity in MS
-
Tubridy N, Behan PO, Capildeo R, et al. The effect of antialpha4 integrin antibody on brain lesion activity inMS: the UKAntegren StudyGroup.Neurology 1999; 53 (3): 466-72 (Pubitemid 29382036)
-
(1999)
Neurology
, vol.53
, Issue.3
, pp. 466-472
-
-
Tubridy, N.1
Behan, P.O.2
Capildeo, R.3
Chaudhuri, A.4
Forbes, R.5
Hawkins, C.P.6
Hughes, R.A.C.7
Palace, J.8
Sharrack, B.9
Swingler, R.10
Young, C.11
Moseley, I.F.12
MacManus, D.G.13
Donoghue, S.14
Miller, D.H.15
-
58
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa020696
-
Miller DH, Khan OA, Sheremata WA, et al. A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348 (1): 15-23 (Pubitemid 36026342)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.1
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.A.5
Libonati, M.A.6
Willmer-Hulme, A.J.7
Dalton, C.M.8
Miszkiel, K.A.9
O'Connor, P.W.10
-
59
-
-
62849118791
-
GLANCE: Results of a phase 2, randomized, double-blind, placebocontrolled study
-
Goodman AD, Rossman H, Bar-Or A, et al. GLANCE: results of a phase 2, randomized, double-blind, placebocontrolled study. Neurology 2009; 72 (9): 806-12
-
(2009)
Neurology
, vol.72
, Issue.9
, pp. 806-12
-
-
Goodman, A.D.1
Rossman, H.2
Bar-Or, A.3
-
60
-
-
33644608613
-
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis
-
Rudick RA, Stuart WH, Calabresi PA, et al. Natalizumab plus interferon beta-1a for relapsing multiple sclerosis. N Engl J Med 2006; 354 (9): 911-23
-
(2006)
N Engl J Med
, vol.354
, Issue.9
, pp. 911-23
-
-
Rudick, R.A.1
Stuart, W.H.2
Calabresi, P.A.3
-
61
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
Polman CH, O'Connor PW, Havrdova E, et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2006; 354 (9): 899-910
-
(2006)
N Engl J Med
, vol.354
, Issue.9
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
-
62
-
-
41849116363
-
Rituximab in relapsing-remitting multiple sclerosis: A 72-week, open-label, phase I trial
-
DOI 10.1002/ana.21363
-
Bar-Or A, Calabresi PA, Arnold D, et al. Rituximab in relapsing-remitting multiple sclerosis: a 72-week, openlabel, phase I trial. Ann Neurol 2008; 63 (3): 395-400 (Pubitemid 351499869)
-
(2008)
Annals of Neurology
, vol.63
, Issue.3
, pp. 395-400
-
-
Bar-Or, A.1
Calabresi, P.A.J.2
Arnlod, D.3
Markowitz, C.4
Shafer, S.5
Kasper, L.H.6
Waubant, E.7
Gazda, S.8
Fox, R.J.9
Panzara, M.10
Sarkar, N.11
Agarwal, S.12
Smith, C.H.13
-
63
-
-
39049142995
-
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
-
DOI 10.1056/NEJMoa0706383
-
Hauser SL, Waubant E, Arnold DL, et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 2008; 358 (7): 676-88 (Pubitemid 351240747)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.7
, pp. 676-688
-
-
Hauser, S.L.1
Waubant, E.2
Arnold, D.L.3
Vollmer, T.4
Antel, J.5
Fox, R.J.6
Bar-Or, A.7
Panzara, M.8
Sarkar, N.9
Agarwal, S.10
Langer-Gould, A.11
Smith, C.H.12
-
64
-
-
70449418132
-
Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial
-
Hawker K, O'Connor P, Freedman MS, et al. Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial. Ann Neurol 2009; 66 (4): 460-71
-
(2009)
Ann Neurol
, vol.66
, Issue.4
, pp. 460-71
-
-
Hawker, K.1
O'Connor, P.2
Freedman, M.S.3
-
65
-
-
77953335494
-
Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: A 52-week phase II trial
-
Naismith RT, Piccio L, Lyons JA, et al. Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial. Neurology 2010; 74 (23): 1860-7
-
(2010)
Neurology
, vol.74
, Issue.23
, pp. 1860-7
-
-
Naismith, R.T.1
Piccio, L.2
Lyons, J.A.3
-
66
-
-
81555202418
-
Ocrelizumab in relapsing-remitting multiple sclerosis: Results of a phase II randomized placebo-controlled multicenter trial
-
Epub Oct 31
-
Kappos L, Li D, Calabresi PA, et al. Ocrelizumab in relapsing-remitting multiple sclerosis: results of a phase II randomized placebo-controlled multicenter trial. Lancet. Epub 2011 Oct 31
-
(2011)
Lancet
-
-
Kappos, L.1
Li, D.2
Calabresi, P.A.3
-
67
-
-
79953222184
-
Magnetic resonance imaging (MRI) efficacy of ofatumumab in relapsing-remitting multiple sclerosis (RRMS): 24-week results of a phase II study
-
[abstract no. 136 plus oral presentation] Oct 13-16; Gothenburg
-
Soelberg Sorensen P, Drulovic J, Havrdova E, et al. Magnetic resonance imaging (MRI) efficacy of ofatumumab in relapsing-remitting multiple sclerosis (RRMS): 24-week results of a phase II study [abstract no. 136 plus oral presentation]. Presented at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS); 2010 Oct 13-16; Gothenburg
-
(2010)
26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
-
-
Soelberg Sorensen, P.1
Drulovic, J.2
Havrdova, E.3
-
68
-
-
54949143968
-
Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
-
Coles AJ, Compston DA, Selmaj KW, et al. Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N Engl J Med 2008; 359 (17): 1786-801
-
(2008)
N Engl J Med
, vol.359
, Issue.17
, pp. 1786-801
-
-
Coles, A.J.1
Compston, D.A.2
Selmaj, K.W.3
-
69
-
-
77949301468
-
Daclizumab in active relapsing multiple sclerosis (CHOICE study): A phase 2 randomised double-blind placebo-controlled add-on trial with interferon beta
-
Wynn D, Kaufman M, Montalban X, et al. Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta. Lancet Neurol 2010; 9 (4): 381-90
-
(2010)
Lancet Neurol
, vol.9
, Issue.4
, pp. 381-90
-
-
Wynn, D.1
Kaufman, M.2
Montalban, X.3
-
70
-
-
48849087125
-
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relap-sing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
-
Segal BM, Constantinescu CS, Raychaudhuri A, et al. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relap-sing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol 2008; 7 (9): 796-804
-
(2008)
Lancet Neurol
, vol.7
, Issue.9
, pp. 796-804
-
-
Segal, B.M.1
Constantinescu, C.S.2
Raychaudhuri, A.3
-
71
-
-
73949152043
-
Design of a four-arm, randomized, placebocontrolled phase II study of 36 weeks of atacicept monotherapy in relapsing multiple sclerosis [abstract]
-
Plitz T. Design of a four-arm, randomized, placebocontrolled phase II study of 36 weeks of atacicept monotherapy in relapsing multiple sclerosis [abstract]. Mult Scler 2008; 14 Suppl. 1: 173
-
(2008)
Mult Scler
, vol.14
, Issue.SUPPL. 1
, pp. 173
-
-
Plitz, T.1
-
72
-
-
73949150766
-
Atacicept: A new B lymphocyte-targeted therapy for multiple sclerosis
-
Hartung HP. Atacicept: a new B lymphocyte-targeted therapy for multiple sclerosis. Nervenarzt 2009; 80 (12): 1462-72
-
(2009)
Nervenarzt
, vol.80
, Issue.12
, pp. 1462-72
-
-
Hartung, H.P.1
-
73
-
-
83455216864
-
Design of an exploratory two-arm, randomized, placebo controlled phase II study of 36 weeks of atacicept treatment in patients with optic neuritis as clinically isolated syndrome [abstract]
-
Sergott R. Design of an exploratory two-arm, randomized, placebo controlled phase II study of 36 weeks of atacicept treatment in patients with optic neuritis as clinically isolated syndrome [abstract]. Mult Scler 2008; 14 Suppl. 1: 177
-
(2008)
Mult Scler
, Issue.14 SUPPL. 1
, pp. 177
-
-
Sergott, R.1
-
74
-
-
34247513840
-
MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS
-
DOI 10.1212/01.wnl.0000260064.77700.fd, PII 0000611420070424000012
-
Miller DH, Soon D, Fernando KT, et al. MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS. Neurology 2007; 68 (17): 1390-401 (Pubitemid 46659091)
-
(2007)
Neurology
, vol.68
, Issue.17
, pp. 1390-1401
-
-
Miller, D.H.1
Soon, D.2
Fernando, K.T.3
MacManus, D.G.4
Barker, G.J.5
Yousry, T.A.6
Fisher, E.7
O'Connor, P.W.8
Phillips, J.T.9
Polman, C.H.10
Kappos, L.11
Hutchinson, M.12
Havrdova, E.13
Lublin, F.D.14
Giovannoni, G.15
Wajgt, A.16
Rudick, R.17
Lynn, F.18
Panzara, M.A.19
Sandrock, A.W.20
more..
-
75
-
-
60049089535
-
Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: A retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study
-
Havrdova E, Galetta S, Hutchinson M, et al. Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study. Lancet Neurol 2009; 8 (3): 254-60
-
(2009)
Lancet Neurol
, vol.8
, Issue.3
, pp. 254-60
-
-
Havrdova, E.1
Galetta, S.2
Hutchinson, M.3
-
76
-
-
41649102740
-
The efficacy of natalizumab monotherapy over 3 years of treatment in patients with relapsing multiple sclerosis
-
[abstract no. P06.082] Apr 28-May 5; Boston (MA)
-
O'Connor P, Goodman A, Kappos L, et al. The efficacy of natalizumab monotherapy over 3 years of treatment in patients with relapsing multiple sclerosis [abstract no. P06.082]. Presented at the 59th Annual Meeting of the American Academy of Neurology; 2007 Apr 28-May 5; Boston (MA)
-
(2007)
59th Annual Meeting of the American Academy of Neurology
-
-
O'Connor, P.1
Goodman, A.2
Kappos, L.3
-
78
-
-
79958137883
-
Disease activity return during natalizumab treatment interruption in patients with multiple sclerosis
-
O'Connor PW, Goodman A, Kappos L, et al. Disease activity return during natalizumab treatment interruption in patients with multiple sclerosis. Neurology 2011; 76 (22): 1858-65
-
(2011)
Neurology
, vol.76
, Issue.22
, pp. 1858-65
-
-
O'Connor, P.W.1
Goodman, A.2
Kappos, L.3
-
79
-
-
34848816850
-
The incidence and significance of anti-natalizumab antibodies: Results from AFFIRM and SENTINEL
-
DOI 10.1212/01.wnl.0000277457.17420.b5
-
Calabresi PA, Giovannoni G, Confavreux C, et al. The incidence and significance of anti-natalizumab antibodies: results from AFFIRM and SENTINEL. Neurology 2007; 69 (14): 1391-403 (Pubitemid 47511460)
-
(2007)
Neurology
, vol.69
, Issue.14
, pp. 1391-1403
-
-
Calabresi, P.A.1
Giovannoni, G.2
Confavreux, C.3
Galetta, S.L.4
Havrdova, E.5
Hutchinson, M.6
Kappos, L.7
Miller, D.H.8
O'Connor, P.W.9
Phillips, J.T.10
Polman, C.H.11
Radue, E.-W.12
Rudick, R.A.13
Stuart, W.H.14
Lublin, F.D.15
Wajgt, A.16
Weinstock-Guttman, B.17
Wynn, D.R.18
Lynn, F.19
Panzara, M.A.20
more..
-
80
-
-
22844439662
-
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
-
DOI 10.1056/NEJMoa051782
-
Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med 2005; 353 (4): 369-74 (Pubitemid 41132341)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.4
, pp. 369-374
-
-
Kleinschmidt-DeMasters, B.K.1
Tyler, K.L.2
-
81
-
-
22844445230
-
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
-
DOI 10.1056/NEJMoa051847
-
Langer-Gould A, Atlas SW, Green AJ, et al. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med 2005; 353 (4): 375-81 (Pubitemid 41132342)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.4
, pp. 375-381
-
-
Langer-Gould, A.1
Atlas, S.W.2
Green, A.J.3
Bollen, A.W.4
Pelletier, D.5
-
82
-
-
22844445587
-
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease
-
DOI 10.1056/NEJMoa051586
-
Van Assche G, Van Ranst M, Sciot R, et al. Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease.NEngl J Med 2005; 353 (4): 362-8 (Pubitemid 41132340)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.4
, pp. 362-368
-
-
Van Assche, G.1
Van Ranst, M.2
Sciot, R.3
Dubois, B.4
Vermeire, S.5
Noman, M.6
Verbeeck, J.7
Geboes, K.8
Robberecht, W.9
Rutgeerts, P.10
-
83
-
-
33644605483
-
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
-
Yousry TA, Major EO, Ryschkewitsch C, et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N Engl J Med 2006; 354 (9): 924-33
-
(2006)
N Engl J Med
, vol.354
, Issue.9
, pp. 924-33
-
-
Yousry, T.A.1
Major, E.O.2
Ryschkewitsch, C.3
-
85
-
-
41649109701
-
The safety of natalizumab in patients with relapsing multiple sclerosis: An update from TOUCH and TYGRIS
-
[abstract no. P06.082] April 28-May 5; Boston (MA)
-
Bozic C, Belcher G, Kroojimans M, et al. The safety of natalizumab in patients with relapsing multiple sclerosis: an update from TOUCH-and TYGRIS [abstract no. P06.082]. Presented at the 59th Annual Meeting of the American Academy of Neurology; 2007 April 28-May 5; Boston (MA)
-
(2007)
59th Annual Meeting of the American Academy of Neurology
-
-
Bozic, C.1
Belcher, G.2
Kroojimans, M.3
-
86
-
-
84920691066
-
-
[online] [Accessed 2011 Jun 30]
-
Biogen Idec.MedInfo [online]. Available fromURL: https://medinfo. biogenidec.com/medinfo/download?doc=Letter +Bodies%2Fnatalizumab+Safety+Update. pdf&type=pmldoc &Continue=Continue [Accessed 2011 Jun 30]
-
Biogen Idec.MedInfo
-
-
-
87
-
-
79960344014
-
Natalizumab treatment for multiple sclerosis: Updated recommendations for patient selection and monitoring
-
Kappos L, Bates D, Edan G, et al. Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring. Lancet Neurol 2011; 10 (8): 745-58
-
(2011)
Lancet Neurol
, vol.10
, Issue.8
, pp. 745-58
-
-
Kappos, L.1
Bates, D.2
Edan, G.3
-
88
-
-
77956361575
-
Assessment of JC virus DNA in blood and urine from natalizumabtreated patients
-
Rudick RA, O'Connor PW, Polman CH, et al. Assessment of JC virus DNA in blood and urine from natalizumabtreated patients. Ann Neurol 2010; 68 (3): 304-10
-
(2010)
Ann Neurol
, vol.68
, Issue.3
, pp. 304-10
-
-
Rudick, R.A.1
O'Connor, P.W.2
Polman, C.H.3
-
89
-
-
70149089482
-
Asymptomatic reactivation of JC virus in patients treated with natalizumab
-
Chen Y, Bord E, Tompkins T, et al. Asymptomatic reactivation of JC virus in patients treated with natalizumab. N Engl J Med 2009; 361 (11): 1067-74
-
(2009)
N Engl J Med
, vol.361
, Issue.11
, pp. 1067-74
-
-
Chen, Y.1
Bord, E.2
Tompkins, T.3
-
90
-
-
77954428012
-
JCV detection in multiple sclerosis patients treated with natalizumab
-
Sadiq SA, Puccio LM, Brydon EW. JCV detection in multiple sclerosis patients treated with natalizumab. J Neurol 2010; 257 (6): 954-8
-
(2010)
J Neurol
, vol.257
, Issue.6
, pp. 954-8
-
-
Sadiq, S.A.1
Puccio, L.M.2
Brydon, E.W.3
-
91
-
-
72449145273
-
Asymptomatic reactivation of JC virus in patients treated with natalizumab
-
Gorelik L, Goelz S, Sandrock AW. Asymptomatic reactivation of JC virus in patients treated with natalizumab. N Engl J Med 2009; 361 (25): 2487-8
-
(2009)
N Engl J Med
, vol.361
, Issue.25
, pp. 2487-8
-
-
Gorelik, L.1
Goelz, S.2
Sandrock, A.W.3
-
92
-
-
76449101519
-
Immune responses to JC virus in patients with multiple sclerosis treated with natalizumab: A cross-sectional and longitudinal study
-
Jilek S, Jaquiery E, Hirsch HH, et al. Immune responses to JC virus in patients with multiple sclerosis treated with natalizumab: a cross-sectional and longitudinal study. Lancet Neurol 2010; 9 (3): 264-72
-
(2010)
Lancet Neurol
, vol.9
, Issue.3
, pp. 264-72
-
-
Jilek, S.1
Jaquiery, E.2
Hirsch, H.H.3
-
93
-
-
77954170279
-
Prevalence and stability of antibodies to the BK and JC polyomaviruses: A long-term longitudinal study of Australians
-
Antonsson A, Green AC, Mallitt KA, et al. Prevalence and stability of antibodies to the BK and JC polyomaviruses: a long-term longitudinal study of Australians. J Gen Virol 2010; 91 (Pt 7): 1849-53
-
(2010)
J Gen Virol
, vol.91
, Issue.PART 7
, pp. 1849-53
-
-
Antonsson, A.1
Green, A.C.2
Mallitt, K.A.3
-
94
-
-
65649099693
-
Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors
-
Egli A, Infanti L, Dumoulin A, et al. Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors. J Infect Dis 2009; 199 (6): 837-46
-
(2009)
J Infect Dis
, vol.199
, Issue.6
, pp. 837-46
-
-
Egli, A.1
Infanti, L.2
Dumoulin, A.3
-
95
-
-
63449123993
-
Seroepidemiology of human polyomaviruses
-
Kean JM, Rao S, Wang M, et al. Seroepidemiology of human polyomaviruses. PLoS Pathog 2009; 5 (3): e1000363
-
(2009)
PLoS Pathog
, vol.5
, Issue.3
-
-
Kean, J.M.1
Rao, S.2
Wang, M.3
-
96
-
-
0141459365
-
Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40
-
DOI 10.1002/jmv.10450
-
Knowles WA, Pipkin P, Andrews W, et al. Populationbased study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol 2003; 71 (1): 115-23 (Pubitemid 37121921)
-
(2003)
Journal of Medical Virology
, vol.71
, Issue.1
, pp. 115-123
-
-
Knowles, W.A.1
Pipkin, P.2
Andrews, N.3
Vyse, A.4
Minor, P.5
Brown, D.W.G.6
Miller, E.7
-
97
-
-
0015611076
-
Prevalence of antibodies in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy
-
Padgett BL, Walker DL. Prevalence of antibodies in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy. J Infect Dis 1973; 127 (4): 467-70
-
(1973)
J Infect Dis
, vol.127
, Issue.4
, pp. 467-70
-
-
Padgett, B.L.1
Walker, D.L.2
-
98
-
-
0038654083
-
Seroepidemiology of the human polyomaviruses
-
DOI 10.1099/vir.0.18842-0
-
Stolt A, Sasnauskas K, Koskela P, et al. Seroepidemiology of the human polyomaviruses. J Gen Virol 2003; 84 (Pt 6): 1499-504 (Pubitemid 36675520)
-
(2003)
Journal of General Virology
, vol.84
, Issue.6
, pp. 1499-1504
-
-
Stolt, A.1
Sasnauskas, K.2
Koskela, P.3
Lehtinen, M.4
Dillner, J.5
-
99
-
-
77956387401
-
Anti-JC virus antibodies: Implications for PML risk stratification
-
Gorelik L, Lerner M, Bixler S, et al. Anti-JC virus antibodies: implications for PML risk stratification. Ann Neurol 2010; 68 (3): 295-303
-
(2010)
Ann Neurol
, vol.68
, Issue.3
, pp. 295-303
-
-
Gorelik, L.1
Lerner, M.2
Bixler, S.3
-
100
-
-
79952536982
-
Assay design and sample collection can affect anti-John Cunningham virus antibody detection
-
Goelz SE, Gorelik L, Subramanyam M. Assay design and sample collection can affect anti-John Cunningham virus antibody detection. Ann Neurol 2011; 69 (2): 429-30
-
(2011)
Ann Neurol
, vol.69
, Issue.2
, pp. 429-30
-
-
Goelz, S.E.1
Gorelik, L.2
Subramanyam, M.3
-
101
-
-
70349440918
-
Primary central nervous system lymphoma in a patient treated with natalizumab
-
Schweikert A, Kremer M, Ringel F, et al. Primary central nervous system lymphoma in a patient treated with natalizumab. Ann Neurol 2009; 66 (3): 403-6
-
(2009)
Ann Neurol
, vol.66
, Issue.3
, pp. 403-6
-
-
Schweikert, A.1
Kremer, M.2
Ringel, F.3
-
102
-
-
70350070224
-
Natalizumab and central nervous system lymphoma: No clear association
-
Bozic C, LaGuette J, Panzara MA, et al. Natalizumab and central nervous system lymphoma: no clear association. Ann Neurol 2009; 66 (3): 261-2
-
(2009)
Ann Neurol
, vol.66
, Issue.3
, pp. 261-2
-
-
Bozic, C.1
Laguette, J.2
Panzara, M.A.3
-
103
-
-
70350558559
-
Ocular toxoplasmosis during natalizumab treatment
-
Zecca C, Nessi F, Bernasconi E, et al. Ocular toxoplasmosis during natalizumab treatment. Neurology 2009; 73 (17): 1418-9
-
(2009)
Neurology
, vol.73
, Issue.17
, pp. 1418-9
-
-
Zecca, C.1
Nessi, F.2
Bernasconi, E.3
-
104
-
-
67649105707
-
Biology and treatment of primary central nervous system lymphoma
-
Algazi AP, Kadoch C, Rubenstein JL. Biology and treatment of primary central nervous system lymphoma. Neurotherapeutics 2009; 6 (3): 587-97
-
(2009)
Neurotherapeutics
, vol.6
, Issue.3
, pp. 587-97
-
-
Algazi, A.P.1
Kadoch, C.2
Rubenstein, J.L.3
-
105
-
-
73449085640
-
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)
-
De AB, Dotti G, Quintarelli C, et al. Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). Blood 2009; 114 (23): 4784-91
-
(2009)
Blood
, vol.114
, Issue.23
, pp. 4784-91
-
-
De Ab Dotti, G.1
Quintarelli, C.2
-
106
-
-
33846006249
-
Primary lymphoma of CNS, mycophenolate mofetil and lupus
-
DOI 10.1177/0961203306071431
-
Finelli PF, Naik K, DiGiuseppe JA, et al. Primary lymphoma of CNS, mycophenolate mofetil and lupus. Lupus 2006; 15 (12): 886-8 (Pubitemid 46044922)
-
(2006)
Lupus
, vol.15
, Issue.12
, pp. 886-888
-
-
Finelli, P.F.1
Naik, K.2
DiGiuseppe, J.A.3
Prasad, A.4
-
107
-
-
38949166754
-
Melanoma complicating treatment with natalizumab for multiple sclerosis [16]
-
Mullen JT, Vartanian TK, Atkins MB. Melanoma complicating treatment with natalizumab for multiple sclerosis. N Engl J Med 2008; 358 (6): 647-8 (Pubitemid 351214309)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.6
, pp. 647-648
-
-
Mullen, J.T.1
Vartanian, T.K.2
Atkins, M.B.3
-
108
-
-
46449083260
-
More on melanoma with transdifferentiation
-
Panzara MA, Bozic C, Sandrock AW. More on melanoma with transdifferentiation.NEngl JMed 2008; 359 (1): 99-100
-
(2008)
NEngl JMed
, vol.359
, Issue.1
, pp. 99-100
-
-
Panzara, M.A.1
Bozic, C.2
Sandrock, A.W.3
-
109
-
-
79955834140
-
Utilisation and safety of natalizumab in patients with relapsing multiple sclerosis
-
[abstract no. P893]
-
Bozic C, Christiano LM, Hyde R, et al. Utilisation and safety of natalizumab in patients with relapsing multiple sclerosis [abstract no. P893]. Mult Scler 2010; 16 Suppl. 10: S315
-
(2010)
Mult Scler
, vol.16
, Issue.SUPPL. 10
-
-
Bozic, C.1
Christiano, L.M.2
Hyde, R.3
-
110
-
-
33646362290
-
B-cell targeting in rheumatoid arthritis and other autoimmune diseases
-
Edwards JC, Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat Rev Immunol 2006; 6 (5): 394-403
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.5
, pp. 394-403
-
-
Edwards, J.C.1
Cambridge, G.2
-
111
-
-
0036179899
-
2 is sufficient for induction of apoptosis in B-cell lines
-
DOI 10.1007/s00262-001-0247-1
-
Cardarelli PM, Quinn M, Buckman D, et al. Binding to CD20 by anti-B1 antibody or F(ab')(2) is sufficient for induction of apoptosis in B-cell lines. Cancer Immunol Immunother 2002; 51 (1): 15-24 (Pubitemid 34158519)
-
(2002)
Cancer Immunology, Immunotherapy
, vol.51
, Issue.1
, pp. 15-24
-
-
Cardarelli, P.M.1
Maire, Q.2
Dana, B.3
Yu, F.4
David, C.5
King, D.J.6
Christopher, B.7
Geoffrey, Y.8
-
112
-
-
0034076307
-
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
-
DOI 10.1038/74704
-
Clynes RA, Towers TL, Presta LG, et al. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 2000; 6 (4): 443-6 (Pubitemid 30208162)
-
(2000)
Nature Medicine
, vol.6
, Issue.4
, pp. 443-446
-
-
Clynes, R.A.1
Towers, T.L.2
Presta, L.G.3
Ravetch, J.V.4
-
113
-
-
0037082469
-
The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism
-
DOI 10.1182/blood.V99.4.1314
-
Pedersen IM, Buhl AM, Klausen P, et al. The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism. Blood 2002; 99 (4): 1314-9 (Pubitemid 34547086)
-
(2002)
Blood
, vol.99
, Issue.4
, pp. 1314-1319
-
-
Pedersen, I.M.1
Buhl, A.M.2
Klausen, P.3
Geisler, C.H.4
Jurlander, J.5
-
114
-
-
0028057250
-
Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
-
Reff ME, Carner K, Chambers KS, et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994; 83 (2): 435-45 (Pubitemid 24030569)
-
(1994)
Blood
, vol.83
, Issue.2
, pp. 435-445
-
-
Reff, M.E.1
Carner, K.2
Chambers, K.S.3
Chinn, P.C.4
Leonard, J.E.5
Raab, R.6
Newman, R.A.7
Hanna, N.8
Anderson, D.R.9
-
115
-
-
0019421518
-
Characterization of a human b cell-specific antigen (B2) distinct from B1
-
Nadler LM, Stashenko P, Hardy R, et al. Characterization of a human B cell-specific antigen (B2) distinct from B1. J Immunol 1981; 126 (5): 1941-7 (Pubitemid 11120986)
-
(1981)
Journal of Immunology
, vol.126
, Issue.5
, pp. 1941-1947
-
-
Nadler, L.M.1
Stashenko, P.2
Hardy, R.3
-
116
-
-
0025751627
-
Analysis of cis-acting elements present in the CD20/B1 antigen promoter
-
Rieckmann P, Wilson GL, Thevenin C, et al. Analysis of cis-acting elements present in the CD20/B1 antigen promoter. J Immunol 1991; 147 (11): 3994-9
-
(1991)
J Immunol
, vol.147
, Issue.11
, pp. 3994-9
-
-
Rieckmann, P.1
Wilson, G.L.2
Thevenin, C.3
-
117
-
-
33751085414
-
Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients
-
DOI 10.1016/j.jneuroim.2006.06.029, PII S0165572806002700
-
Cross AH, Stark JL, Lauber J, et al. Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients. J Neuroimmunol 2006; 180 (1-2): 63-70 (Pubitemid 44767709)
-
(2006)
Journal of Neuroimmunology
, vol.180
, Issue.1-2
, pp. 63-70
-
-
Cross, A.H.1
Stark, J.L.2
Lauber, J.3
Ramsbottom, M.J.4
Lyons, J.-A.5
-
118
-
-
26444598492
-
Clinical stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis
-
DOI 10.1001/archneur.62.10.1620
-
Stuve O, Cepok S, Elias B, et al. Clinical stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis. Arch Neurol 2005; 62 (10): 1620-3 (Pubitemid 41434570)
-
(2005)
Archives of Neurology
, vol.62
, Issue.10
, pp. 1620-1623
-
-
Stuve, O.1
Cepok, S.2
Elias, B.3
Saleh, A.4
Hartung, H.-P.5
Hemmer, B.6
Kieseier, B.C.7
-
119
-
-
77953341196
-
Changes in B-and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis
-
Piccio L, Naismith RT, Trinkaus K, et al. Changes in B-and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis. Arch Neurol 2010; 67 (6): 707-14
-
(2010)
Arch Neurol
, vol.67
, Issue.6
, pp. 707-14
-
-
Piccio, L.1
Naismith, R.T.2
Trinkaus, K.3
-
120
-
-
0034000056
-
Rituximab: Active treatment of central nervus system involvement by non- Hodgkin's lymphoma? [2]
-
DOI 10.1023/A:1008371602708
-
Ruhstaller TW, Amsler U, Cerny T. Rituximab: active treatment of central nervous system involvement by non-Hodgkin's lymphoma? Ann Oncol 2000; 11 (3): 374-5 (Pubitemid 30214681)
-
(2000)
Annals of Oncology
, vol.11
, Issue.3
, pp. 374-375
-
-
Ruhstaller, T.W.1
Amsler, U.2
Cerny, T.3
-
121
-
-
0037438494
-
Rituximab therapy for CNS lymphomas: Targeting the leptomeningeal compartment
-
DOI 10.1182/blood-2002-06-1636
-
Rubenstein JL, Combs D, Rosenberg J, et al. Rituximab therapy for CNS lymphomas: targeting the leptomeningeal compartment. Blood 2003; 101 (2): 466-8 (Pubitemid 36077565)
-
(2003)
Blood
, vol.101
, Issue.2
, pp. 466-468
-
-
Rubenstein, J.L.1
Combs, D.2
Rosenberg, J.3
Levy, A.4
McDermott, M.5
Damon, L.6
Ignoffo, R.7
Aldape, K.8
Shen, A.9
Lee, D.10
Grillo-Lopez, A.11
Shuman, M.A.12
-
122
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
DOI 10.1002/art.22025
-
Cohen SB, Emery P, Greenwald MW, et al. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum 2006; 54 (9): 2793-806 (Pubitemid 44497758)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.9
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
Dougados, M.4
Furie, R.A.5
Genovese, M.C.6
Keystone, E.C.7
Loveless, J.E.8
Burmester, G.-R.9
Cravets, M.W.10
Hessey, E.W.11
Shaw, T.12
Totoritis, M.C.13
-
123
-
-
33646894910
-
Rituximab: A review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
-
DOI 10.2165/00003495-200666060-00005
-
Cvetkovic RS, Perry CM. Rituximab: a review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia. Drugs 2006; 66 (6): 791-820 (Pubitemid 43778729)
-
(2006)
Drugs
, vol.66
, Issue.6
, pp. 791-820
-
-
Cvetkovic, R.S.1
Perry, C.M.2
-
124
-
-
2942537697
-
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
-
DOI 10.1056/NEJMoa032534
-
Edwards JC, Szczepanski L, Szechinski J, et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 2004; 350 (25): 2572-81 (Pubitemid 38758544)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.25
, pp. 2572-2581
-
-
Edwards, J.C.W.1
Szczepanski, L.2
Szechinski, J.3
Filipowicz-Sosnowska, A.4
Emery, P.5
Close, D.R.6
Stevens, R.M.7
Shaw, T.8
-
125
-
-
33645960424
-
Primary chronic cold agglutinin disease: A population based clinical study of 86 patients
-
Berentsen S, Ulvestad E, Langholm B, et al. Primary chronic cold agglutinin disease: a population based clinical study of 86 patients. Haematologica 2006; 91 (4): 460-6
-
(2006)
Haematologica
, vol.91
, Issue.4
, pp. 460-6
-
-
Berentsen, S.1
Ulvestad, E.2
Langholm, B.3
-
126
-
-
58149464696
-
A review of the current use of rituximab in autoimmune diseases
-
Gurcan HM, Keskin DB, Stern JN, et al. A review of the current use of rituximab in autoimmune diseases. Int Immunopharmacol 2009; 9 (1): 10-25
-
(2009)
Int Immunopharmacol
, vol.9
, Issue.1
, pp. 10-25
-
-
Gurcan, H.M.1
Keskin, D.B.2
Stern, J.N.3
-
127
-
-
33750592244
-
Successful treatment of cold agglutinin disease with anti-CD20 antibody (rituximab) in a patient with systemic lupus erythematosus
-
DOI 10.1177/0961203306070983
-
Kotani T, Takeuchi T, Kawasaki Y, et al. Successful treatment of cold agglutinin disease with anti-CD20 antibody (rituximab) in a patient with systemic lupus erythematosus. Lupus 2006; 15 (10): 683-5 (Pubitemid 44682831)
-
(2006)
Lupus
, vol.15
, Issue.10
, pp. 683-685
-
-
Kotani, T.1
Takeuchi, T.2
Kawasaki, Y.3
Hirano, S.4
Tabushi, Y.5
Kagitani, M.6
Makino, S.7
Hanafusa, T.8
-
128
-
-
25444437442
-
Rituximab treatment in patients with primary Sjögren's syndrome: An open-label phase II study
-
DOI 10.1002/art.21260
-
Pijpe J, van Imhoff GW, Spijkervet FK, et al. Rituximab treatment in patients with primary Sjogren's syndrome: an open-label phase II study. Arthritis Rheum 2005; 52 (9): 2740-50 (Pubitemid 41369102)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.9
, pp. 2740-2750
-
-
Pijpe, J.1
Van Imhoff, G.W.2
Spijkervet, F.K.L.3
Roodenburg, J.L.N.4
Wolbink, G.J.5
Mansour, K.6
Vissink, A.7
Kallenberg, C.G.M.8
Bootsma, H.9
-
129
-
-
0038603204
-
Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon α with an anti-CD20
-
DOI 10.1182/blood-2002-10-3162
-
Sansonno D, De Re V, Lauletta G, et al. Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon alpha with an anti-CD20. Blood 2003; 101 (10): 3818-26 (Pubitemid 36857852)
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 3818-3826
-
-
Sansonno, D.1
De Re, V.2
Lauletta, G.3
Tucci, F.A.4
Boiocchi, M.5
Dammacco, F.6
-
130
-
-
0242318191
-
Rituximab for immune cytopenia in adults: Idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and Evans syndrome
-
Shanafelt TD, Madueme HL, Wolf RC, et al. Rituximab for immune cytopenia in adults: idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and Evans syndrome. Mayo Clin Proc 2003; 78 (11): 1340-6 (Pubitemid 37337779)
-
(2003)
Mayo Clinic Proceedings
, vol.78
, Issue.11
, pp. 1340-1346
-
-
Shanafelt, T.D.1
Madueme, H.L.2
Wolf, R.C.3
Tefferi, A.4
-
131
-
-
34147193717
-
Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system
-
DOI 10.1136/ard.2006.057885
-
Tokunaga M, Saito K, Kawabata D, et al. Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system. Ann Rheum Dis 2007; 66 (4): 470-5 (Pubitemid 46580466)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.4
, pp. 470-475
-
-
Tokunaga, M.1
Saito, K.2
Kawabata, D.3
Imura, Y.4
Fujii, T.5
Nakayamada, S.6
Tsujimura, S.7
Nawata, M.8
Iwata, S.9
Azuma, T.10
Mimori, T.11
Tanaka, Y.12
-
132
-
-
34547185482
-
Treatment of refractory chronic GVHD with rituximab: A GITMO study
-
DOI 10.1038/sj.bmt.1705725, PII 1705725
-
Zaja F, Bacigalupo A, Patriarca F, et al. Treatment of refractory chronic GVHD with rituximab: a GITMO study. Bone Marrow Transplant 2007; 40 (3): 273-7 (Pubitemid 47108472)
-
(2007)
Bone Marrow Transplantation
, vol.40
, Issue.3
, pp. 273-277
-
-
Zaja, F.1
Bacigalupo, A.2
Patriarca, F.3
Stanzani, M.4
Van Lint, M.T.5
Fili, C.6
Scime, R.7
Milone, G.8
Falda, M.9
Vener, C.10
Laszlo, D.11
Alessandrino, P.E.12
Narni, F.13
Sica, S.14
Olivieri, A.15
Sperotto, A.16
Bosi, A.17
Bonifazi, F.18
Fanin, R.19
-
133
-
-
33947671405
-
Rituximab and its role as maintenance therapy in non-Hodgkin lymphoma
-
DOI 10.1586/14737140.7.3.257
-
Collins-Burow B, Santos ES. Rituximab and its role as maintenance therapy in non-Hodgkin lymphoma. Expert Rev Anticancer Ther 2007; 7 (3): 257-73 (Pubitemid 46499210)
-
(2007)
Expert Review of Anticancer Therapy
, vol.7
, Issue.3
, pp. 257-273
-
-
Collins-Burrow, B.1
Santos, E.S.2
-
134
-
-
29344460633
-
The therapeutic potential of anti-CD20: What do B-cells do?
-
DOI 10.1016/j.clim.2005.08.006, PII S1521661605002858
-
Eisenberg R, Looney RJ. The therapeutic potential of anti-CD20 'what do B-cells do?'. Clin Immunol 2005; 117 (3): 207-13 (Pubitemid 43005207)
-
(2005)
Clinical Immunology
, vol.117
, Issue.3
, pp. 207-213
-
-
Eisenberg, R.1
Looney, R.J.2
-
135
-
-
13444274684
-
Effect of rituximab on the peripheral blood and cerebrospinal fluid B cells in patients with primary progressive multiple sclerosis
-
DOI 10.1001/archneur.62.2.258
-
Monson NL, Cravens PD, Frohman EM, et al. Effect of rituximab on the peripheral blood and cerebrospinal fluid B cells in patients with primary progressive multiple sclerosis. Arch Neurol 2005; 62 (2): 258-64 (Pubitemid 40204747)
-
(2005)
Archives of Neurology
, vol.62
, Issue.2
, pp. 258-264
-
-
Monson, N.L.1
Cravens, P.D.2
Frohman, E.M.3
Hawker, K.4
Racke, M.K.5
-
136
-
-
77951757865
-
Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?
-
Bar-Or A, Fawaz L, Fan B, et al. Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS? Ann Neurol 2010; 67 (4): 452-61
-
(2010)
Ann Neurol
, vol.67
, Issue.4
, pp. 452-61
-
-
Bar-Or, A.1
Fawaz, L.2
Fan, B.3
-
137
-
-
67649660703
-
Rituximab and progressive multifocal leukoencephalopathy: The jury is deliberating
-
Carson KR, Bennett CL. Rituximab and progressive multifocal leukoencephalopathy: the jury is deliberating. Leuk Lymphoma 2009; 50 (3): 323-4
-
(2009)
Leuk Lymphoma
, vol.50
, Issue.3
, pp. 323-4
-
-
Carson, K.R.1
Bennett, C.L.2
-
138
-
-
67651158993
-
Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: A Review from the Research on Adverse Drug Events and Reports (RADAR) Project
-
Carson KR, Focosi D, Major EO, et al. Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project. Lancet Oncol 2009; 10 (8): 816-24
-
(2009)
Lancet Oncol
, vol.10
, Issue.8
, pp. 816-24
-
-
Carson, K.R.1
Focosi, D.2
Major, E.O.3
-
139
-
-
83455216865
-
Data on file
-
Data on file, Hoffmann-La Roche, 2010
-
(2010)
Hoffmann-La Roche
-
-
-
140
-
-
51849148443
-
Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, doseranging study
-
Genovese MC, Kaine JL, Lowenstein MB, et al. Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I/II randomized, blinded, placebo-controlled, doseranging study. Arthritis Rheum 2008; 58 (9): 2652-61
-
(2008)
Arthritis Rheum
, vol.58
, Issue.9
, pp. 2652-61
-
-
Genovese, M.C.1
Kaine, J.L.2
Lowenstein, M.B.3
-
141
-
-
78651376557
-
New anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoid malignancies
-
Robak T, Robak E. New anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoid malignancies. Biodrugs 2011; 25 (1): 13-25
-
(2011)
Biodrugs
, vol.25
, Issue.1
, pp. 13-25
-
-
Robak, T.1
Robak, E.2
-
142
-
-
0035794194
-
High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
-
Shields RL, Namenuk AK, Hong K, et al. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem 2001; 276 (9): 6591-604
-
(2001)
J Biol Chem
, vol.276
, Issue.9
, pp. 6591-604
-
-
Shields, R.L.1
Namenuk, A.K.2
Hong, K.3
-
144
-
-
80053539837
-
Serious infections with ocrelizumab in rheumatoid arthritis: Pooled results from double-blind periods of the ocrelizumab phase III RA program [abstract]
-
Emery P, Rigby W, Tak PP, et al. Serious infections with ocrelizumab in rheumatoid arthritis: pooled results from double-blind periods of the ocrelizumab phase III RA program [abstract]. Arthritis Rheum 2010; 62 Suppl. 10: 414
-
(2010)
Arthritis Rheum
, vol.62
, Issue.SUPPL. 10
, pp. 414
-
-
Emery, P.1
Rigby, W.2
Tak, P.P.3
-
145
-
-
78649813499
-
HuMab-7D8 a monoclonal antibody directed against the membraneproximal small loop epitope of CD20 can effectively eliminate CD20low expressing tumor cells that resist rituximab mediated lysis
-
van Meerten T, Rozemuller H, Hol S, et al. HuMab-7D8, a monoclonal antibody directed against the membraneproximal small loop epitope of CD20 can effectively eliminate CD20low expressing tumor cells that resist rituximab mediated lysis. Haematologica 2010; 95 (12): 2063-71
-
(2010)
Haematologica
, vol.95
, Issue.12
, pp. 2063-71
-
-
Van Meerten, T.1
Rozemuller, H.2
Hol, S.3
-
146
-
-
77950080700
-
Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC
-
Natsume A, Niwa R, Satoh M. Improving effector functions of antibodies for cancer treatment: enhancing ADCC and CDC. Drug Des Devel Ther 2009; 3: 7-16
-
(2009)
Drug des Devel Ther
, vol.3
, pp. 7-16
-
-
Natsume, A.1
Niwa, R.2
Satoh, M.3
-
147
-
-
77955300283
-
Ofatumumab, a novel anti-CD20 monoclonal antibody for the treatment of B-cell malignancies
-
Cheson BD. Ofatumumab, a novel anti-CD20 monoclonal antibody for the treatment of B-cell malignancies. J Clin Oncol 2010; 28 (21): 3525-30
-
(2010)
J Clin Oncol
, vol.28
, Issue.21
, pp. 3525-30
-
-
Cheson, B.D.1
-
148
-
-
77955386129
-
Ofatumumab a human anti-CD20 monoclonal antibody for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized double-blind placebo-controlled phase I/II study
-
Ostergaard M, Baslund B, Rigby W, et al. Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: results of a randomized, double-blind, placebo-controlled, phase I/II study. Arthritis Rheum 2010; 62 (8): 2227-38
-
(2010)
Arthritis Rheum
, vol.62
, Issue.8
, pp. 2227-38
-
-
Ostergaard, M.1
Baslund, B.2
Rigby, W.3
-
149
-
-
33845357270
-
First clinical results of HuMAx-CD20 fully human monoclonal IGG1 antibody treatment in rheumatoid arthritis
-
[abstract no. P0018]
-
Ostergaard M, Wiell C, Dawes P, et al. First clinical results of HuMAx-CD20 fully human monoclonal IGG1 antibody treatment in rheumatoid arthritis [abstract no. P0018]. Ann Rheum Dis 2006; 65 Suppl. 2: 58
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.SUPPL. 2
, pp. 58
-
-
Ostergaard, M.1
Wiell, C.2
Dawes, P.3
-
150
-
-
38949185742
-
Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: A phase 1-2 study
-
DOI 10.1182/blood-2007-09-111781
-
Coiffier B, Lepretre S, Pedersen LM, et al. Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: a phase 1-2 study. Blood 2008; 111 (3): 1094-100 (Pubitemid 351213387)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1094-1100
-
-
Coiffier, B.1
Lepretre, S.2
Pedersen, L.M.3
Gadeberg, O.4
Fredriksen, H.5
Van Oers, M.H.J.6
Wooldridge, J.7
Kloczko, J.8
Holowiecki, J.9
Hellmann, A.10
Walewski, J.11
Flensburg, M.12
Petersen, J.13
Robak, T.14
-
151
-
-
47049124865
-
First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: Results of a phase 1/2 trial
-
Hagenbeek A, Gadeberg O, Johnson P, et al. First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase 1/2 trial. Blood 2008; 111 (12): 5486-95
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5486-95
-
-
Hagenbeek, A.1
Gadeberg, O.2
Johnson, P.3
-
152
-
-
84855760055
-
-
Genmab US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL [Accessed 2008 Mar 18]
-
Genmab. A double-blind, randomized, placebo-controlled, multicenter, dose-finding trial of ofatumumab in RRMS patients [ClinicalTrials.gov identifier NCT00640328]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2008 Mar 18]
-
A Double-blind, Randomized, Placebo-controlled, Multicenter, Dose-finding Trial of Ofatumumab in RRMS Patients [ClinicalTrials.gov Identifier NCT00640328]
-
-
-
154
-
-
0027240401
-
Effect of CAMPATH-1H antibody on human hematopoietic progenitors in vitro
-
Gilleece MH, Dexter TM. Effect of Campath-1H antibody on human hematopoietic progenitors in vitro. Blood 1993; 82 (3): 807-12 (Pubitemid 23221659)
-
(1993)
Blood
, vol.82
, Issue.3
, pp. 807-812
-
-
Gilleece, M.H.1
Dexter, T.M.2
-
155
-
-
0023911111
-
Reshaping human antibodies for therapy
-
DOI 10.1038/332323a0
-
RiechmannL,ClarkM,WaldmannH, et al.Reshaping human antibodies for therapy. Nature 1988; 332 (6162): 323-7 (Pubitemid 18091075)
-
(1988)
Nature
, vol.332
, Issue.6162
, pp. 323-327
-
-
Riechmann, L.1
Clark, M.2
Waldmann, H.3
Winter, G.4
-
156
-
-
27944439639
-
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
-
DOI 10.1002/eji.200535075
-
Cox AL, Thompson SA, Jones JL, et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005; 35 (11): 3332-42 (Pubitemid 41672537)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.11
, pp. 3332-3342
-
-
Cox, A.L.1
Thompson, S.A.J.2
Jones, J.L.3
Robertson, V.H.4
Hale, G.5
Waldmann, H.6
Compston, D.A.S.7
Coles, A.J.8
-
157
-
-
0033552391
-
Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis
-
DOI 10.1016/S0140-6736(99)02429-0
-
Coles AJ, Wing M, Smith S, et al. Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Lancet 1999; 354 (9191): 1691-5 (Pubitemid 29533060)
-
(1999)
Lancet
, vol.354
, Issue.9191
, pp. 1691-1695
-
-
Coles, A.J.1
Wing, M.2
Smith, S.3
Coraddu, F.4
Greer, S.5
Taylor, C.6
Weetman, A.7
Hale, G.8
Chatterjee, V.K.9
Waldmann, H.10
Compston, A.11
-
158
-
-
31544467633
-
The window of therapeutic opportunity in multiple sclerosis: Evidence from monoclonal antibody therapy
-
DOI 10.1007/s00415-005-0934-5
-
Coles AJ, Cox A, Le PE, et al. The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol 2006; 253 (1): 98-108 (Pubitemid 43157395)
-
(2006)
Journal of Neurology
, vol.253
, Issue.1
, pp. 98-108
-
-
Coles, A.J.1
Cox, A.2
Le Page, E.3
Jones, J.4
Trip, S.A.5
Deans, J.6
Seaman, S.7
Miller, D.H.8
Hale, G.9
Waldmann, H.10
Compston, D.A.11
-
159
-
-
77249114139
-
B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis
-
Thompson SA, Jones JL, Cox AL, et al. B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis. J Clin Immunol 2010; 30 (1): 99-105
-
(2010)
J Clin Immunol
, vol.30
, Issue.1
, pp. 99-105
-
-
Thompson, S.A.1
Jones, J.L.2
Cox, A.L.3
-
160
-
-
0032882173
-
Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
-
DOI 10.1002/1531-8249(199909)46:3<296::AID-ANA4>3.0.CO;2-#
-
Coles AJ, Wing MG, Molyneux P, et al. Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis. Ann Neurol 1999; 46 (3): 296-304 (Pubitemid 29416266)
-
(1999)
Annals of Neurology
, vol.46
, Issue.3
, pp. 296-304
-
-
Coles, A.J.1
Wing, M.G.2
Molyneux, P.3
Paolillo, A.4
Davie, C.M.5
Hale, G.6
Miller, D.7
Waldmann, H.8
Compston, A.9
-
161
-
-
0028346432
-
Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis
-
DOI 10.1016/S0140-6736(94)91339-0
-
Moreau T, Thorpe J, Miller D, et al. Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis. Lancet 1994; 344 (8918): 298-301 (Pubitemid 24230297)
-
(1994)
Lancet
, vol.344
, Issue.8918
, pp. 298-301
-
-
Moreau, T.1
Thorpe, J.2
Miller, D.3
Moseley, I.4
Hale, G.5
Waldmann, H.6
Clayton, D.7
Wing, M.8
Scolding, N.9
Compston, A.10
-
162
-
-
80053207130
-
Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort
-
Cossburn M, Pace AA, Jones J, et al. Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort. Neurology 2011; 77 (6): 573-9
-
(2011)
Neurology
, vol.77
, Issue.6
, pp. 573-9
-
-
Cossburn, M.1
Pace, A.A.2
Jones, J.3
-
163
-
-
68849084141
-
IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)
-
Jones JL, Phuah CL, Cox AL, et al. IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J Clin Invest 2009; 119 (7): 2052-61
-
(2009)
J Clin Invest
, vol.119
, Issue.7
, pp. 2052-61
-
-
Jones, J.L.1
Phuah, C.L.2
Cox, A.L.3
-
164
-
-
70349382808
-
-
Genzyme [Clinical Trials.gov identifier NCT00530348] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL [Accessed 2011 Jun 30]
-
Genzyme. Comparison of Alemtuzumab and Rebif-Efficacy in Multiple Sclerosis, Study One (CARE-MS I). [Clinical Trials.gov identifier NCT00530348] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2011 Jun 30]
-
Comparison of Alemtuzumab and Rebif-Efficacy in Multiple Sclerosis, Study One (CARE-MS I)
-
-
-
165
-
-
77956154281
-
-
Genzyme [Clinical Trials.gov identifier NCT00548405] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL [Accessed 2011 Jun 30]
-
Genzyme. Comparison of Alemtuzumab and Rebif-Efficacy in Multiple Sclerosis, Study Two (CARE-MS II). [Clinical Trials.gov identifier NCT00548405] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2011 Jun 30]
-
Comparison of Alemtuzumab and Rebif-Efficacy in Multiple Sclerosis, Study Two (CARE-MS II)
-
-
-
166
-
-
0025967435
-
A randomized prospective trial of anti-Tac monoclonal anti-body in human renal transplantation
-
Kirkman RL, Shapiro ME, Carpenter CB, et al. A randomized prospective trial of anti-Tac monoclonal anti-body in human renal transplantation. Transplant Proc 1991; 23 (1 Pt 2): 1066-7
-
(1991)
Transplant Proc
, vol.23
, Issue.1 PART 2
, pp. 1066-7
-
-
Kirkman, R.L.1
Shapiro, M.E.2
Carpenter, C.B.3
-
167
-
-
37149023520
-
Humanized anti-CD25 antibody treatment with daclizumab in multiple sclerosis
-
DOI 10.1159/000109934
-
Martin R. Humanized anti-CD25 antibody treatment with daclizumab in multiple sclerosis. Neurodegener Dis 2008; 5 (1): 23-6 (Pubitemid 350261812)
-
(2008)
Neurodegenerative Diseases
, vol.5
, Issue.1
, pp. 23-26
-
-
Martin, R.1
-
168
-
-
0022365533
-
Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia
-
Waldmann TA, Longo DL, Leonard WJ, et al. Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia. Cancer Res 1985; 45 (9 Suppl.): 4559s-62s (Pubitemid 16223294)
-
(1985)
Cancer Research
, vol.45
, Issue.9 SUPPL.
-
-
Waldmann, T.A.1
Longo, D.L.2
Leonard, W.J.3
-
169
-
-
0019421207
-
A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells
-
Uchiyama T, Broder S, Waldmann TA. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells: I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. J Immunol 1981; 126 (4): 1393-7 (Pubitemid 11149233)
-
(1981)
Journal of Immunology
, vol.126
, Issue.4
, pp. 1393-1397
-
-
Uchiyama, T.1
Broder, S.2
Waldmann, T.A.3
-
170
-
-
33645812129
-
Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis
-
Bielekova B, Catalfamo M, Reichert-Scrivner S, et al. Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. Proc Natl Acad Sci USA 2006; 103 (15): 5941-6
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.15
, pp. 5941-6
-
-
Bielekova, B.1
Catalfamo, M.2
Reichert-Scrivner, S.3
-
171
-
-
0031786786
-
The use of antibodies against the IL-2 receptor in transplantation
-
DOI 10.1016/S0952-7915(98)80215-X
-
Waldmann TA, O'Shea J. The use of antibodies against the IL-2 receptor in transplantation. Curr Opin Immunol 1998; 10 (5): 507-12 (Pubitemid 28479180)
-
(1998)
Current Opinion in Immunology
, vol.10
, Issue.5
, pp. 507-512
-
-
Waldmann, T.A.1
O'Shea, J.2
-
172
-
-
41949097030
-
The biology of interleukin-2
-
DOI 10.1146/annurev.immunol.26.021607.090357
-
Malek TR. The biology of interleukin-2. Annu Rev Immunol 2008; 26: 453-79 (Pubitemid 351600382)
-
(2008)
Annual Review of Immunology
, vol.26
, pp. 453-479
-
-
Malek, T.R.1
-
173
-
-
65249138318
-
Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis
-
Bielekova B, Howard T, Packer AN, et al. Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis. Arch Neurol 2009; 66 (4): 483-9
-
(2009)
Arch Neurol
, vol.66
, Issue.4
, pp. 483-9
-
-
Bielekova, B.1
Howard, T.2
Packer, A.N.3
-
174
-
-
28644435097
-
Use of IL-2 receptor antagonists to reduce delayed graft function following renal transplantation: A review
-
DOI 10.1111/j.1399-0012.2005.00417.x
-
Sandrini S. Use of IL-2 receptor antagonists to reduce delayed graft function following renal transplantation: a review. Clin Transplant 2005; 19 (5): 705-10 (Pubitemid 41748720)
-
(2005)
Clinical Transplantation
, vol.19
, Issue.6
, pp. 705-710
-
-
Sandrini, S.1
-
175
-
-
0031770389
-
Reduction in HTLV-I proviral load and spontaneous lymphoproliferation in HTLV-I-associated myelopathy/tropical spastic paraparesis patients treated with humanized anti-Tac
-
Lehky TJ, Levin MC, Kubota R, et al. Reduction in HTLV-I proviral load and spontaneous lymphoproliferation in HTLV-I-associated myelopathy/tropical spastic paraparesis patients treated with humanized anti-Tac. Ann Neurol 1998; 44 (6): 942-7 (Pubitemid 28558256)
-
(1998)
Annals of Neurology
, vol.44
, Issue.6
, pp. 942-947
-
-
Lehky, T.J.1
Levin, M.C.2
Kubota, R.3
Bamford, R.N.4
Flerlage, A.N.5
Soldan, S.S.6
Leist, T.P.7
Xavier, A.8
White, J.D.9
Brown, M.10
Fleisher, T.A.11
Top, L.E.12
Light, S.13
McFarland, H.F.14
Waldmann, T.A.15
Jacobson, S.16
-
176
-
-
13044311376
-
Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: A phase I/II clinical trial
-
DOI 10.1073/pnas.96.13.7462
-
Nussenblatt RB, Fortin E, Schiffman R, et al. Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial. Proc Natl Acad Sci USA 1999; 96 (13): 7462-6 (Pubitemid 29299684)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.13
, pp. 7462-7466
-
-
Nussenblatt, R.B.1
Fortin, E.2
Schiffman, R.3
Rizzo, L.4
Smith, J.5
Van Veldhuisen, P.6
Sran, P.7
Yaffe, A.8
Goldman, C.K.9
Waldmann, T.A.10
Whitcup, S.M.11
-
177
-
-
33846868833
-
Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: A 25-year personal odyssey
-
DOI 10.1007/s10875-006-9060-0
-
Waldmann TA. Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey. J Clin Immunol 2007; 27 (1): 1-18 (Pubitemid 46224930)
-
(2007)
Journal of Clinical Immunology
, vol.27
, Issue.1
, pp. 1-18
-
-
Waldmann, T.A.1
-
178
-
-
2942537826
-
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β
-
DOI 10.1073/pnas.0402653101
-
Bielekova B, Richert N, Howard T, et al. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc Natl Acad Sci USA 2004; 101 (23): 8705-8 (Pubitemid 38745835)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.23
, pp. 8705-8708
-
-
Bielekova, B.1
Richert, N.2
Howard, T.3
Blevins, G.4
Markovic-Plese, S.5
McCartin, J.6
Wurfel, J.7
Ohayon, J.8
Waldmann, T.A.9
McFarland, H.F.10
Martin, R.11
-
179
-
-
9644265478
-
Treatment of multiple sclerosis with an anti-interleukin-2 receptor monoclonal antibody
-
DOI 10.1002/ana.20287
-
Rose JW, Watt HE, White AT, et al. Treatment of multiple sclerosis with an anti-interleukin-2 receptor monoclonal antibody. Ann Neurol 2004; 56 (6): 864-7 (Pubitemid 39578450)
-
(2004)
Annals of Neurology
, vol.56
, Issue.6
, pp. 864-867
-
-
Rose, J.W.1
Watt, H.E.2
White, A.T.3
Carlson, N.G.4
-
180
-
-
34548142973
-
Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results
-
DOI 10.1212/01.wnl.0000267662.41734.1f, PII 0000611420070821000012
-
Rose JW, Burns JB, Bjorklund J, et al. Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results. Neurology 2007; 69 (8): 785-9 (Pubitemid 47300936)
-
(2007)
Neurology
, vol.69
, Issue.8
, pp. 785-789
-
-
Rose, J.W.1
Burns, J.B.2
Bjorklund, J.3
Klein, J.4
Watt, H.E.5
Carlson, N.G.6
-
182
-
-
59349117317
-
Daclizumab in treatment of multiple sclerosis patients
-
Ali EN, Healy BC, Stazzone LA, et al. Daclizumab in treatment of multiple sclerosis patients. Mult Scler 2009; 15 (2): 272-4
-
(2009)
Mult Scler
, vol.15
, Issue.2
, pp. 272-4
-
-
Ali, E.N.1
Healy, B.C.2
Stazzone, L.A.3
-
183
-
-
36348989105
-
Case records of the massachusetts general hospital. Case 36-2007: A 31-yearold woman with rash, fever, and hypotension
-
Sabatine MS, Poh KK, Mega JL, et al. Case records of the Massachusetts General Hospital. Case 36-2007: a 31-yearold woman with rash, fever, and hypotension. N Engl J Med 2007; 357 (21): 2167-78
-
(2007)
N Engl J Med
, vol.357
, Issue.21
, pp. 2167-78
-
-
Sabatine, M.S.1
Poh, K.K.2
Mega, J.L.3
-
184
-
-
0036884860
-
Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody
-
Brok HP, van Meurs M, Blezer E, et al. Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody. J Immunol 2002; 169 (11): 6554-63 (Pubitemid 36903508)
-
(2002)
Journal of Immunology
, vol.169
, Issue.11
, pp. 6554-6563
-
-
Brok, H.P.M.1
Van Meurs, M.2
Blezer, E.3
Schantz, A.4
Peritt, D.5
Treacy, G.6
Laman, J.D.7
Bauer, J.8
'T Hart, B.A.9
-
185
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
DOI 10.1038/nature01355
-
Cua DJ, Sherlock J, Chen Y, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003; 421 (6924): 744-8 (Pubitemid 36227625)
-
(2003)
Nature
, vol.421
, Issue.6924
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
186
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201 (2): 233-40 (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
187
-
-
33846593869
-
Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
-
DOI 10.1093/brain/awl273
-
Li Y, Chu N, Hu A, et al. Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. Brain 2007; 130 (Pt 2): 490-501 (Pubitemid 46181102)
-
(2007)
Brain
, vol.130
, Issue.2
, pp. 490-501
-
-
Li, Y.1
Chu, N.2
Hu, A.3
Gran, B.4
Rostami, A.5
Zhang, G.-X.6
-
188
-
-
33744936550
-
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
-
Vaknin-Dembinsky A, Balashov K, Weiner HL. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol 2006; 176 (12): 7768-74 (Pubitemid 43849078)
-
(2006)
Journal of Immunology
, vol.176
, Issue.12
, pp. 7768-7774
-
-
Vaknin-Dembinsky, A.1
Balashov, K.2
Weiner, H.L.3
-
189
-
-
0028809507
-
Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
-
Windhagen A, Newcombe J, Dangond F, et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med 1995; 182 (6): 1985-96
-
(1995)
J Exp Med
, vol.182
, Issue.6
, pp. 1985-96
-
-
Windhagen, A.1
Newcombe, J.2
Dangond, F.3
-
190
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13 (5): 715-25
-
(2000)
Immunity
, vol.13
, Issue.5
, pp. 715-25
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
-
191
-
-
0029557309
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions
-
DOI 10.1016/0923-2494(96)83011-2
-
Trinchieri G, Scott P. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions. Res Immunol 1995; 146 (7-8): 423-31 (Pubitemid 26054833)
-
(1995)
Research in Immunology
, vol.146
, Issue.7-8
, pp. 423-431
-
-
Trinchieri, G.1
Scott, P.2
-
192
-
-
33750282677
-
17 axis: Therapeutic targets for autoimmune inflammation
-
DOI 10.1016/j.coi.2006.09.008, PII S0952791506001932
-
Kikly K, Liu L, Na S, et al. The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation. Curr Opin Immunol 2006; 18 (6): 670-5 (Pubitemid 44635178)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.6
, pp. 670-675
-
-
Kikly, K.1
Liu, L.2
Na, S.3
Sedgwick, J.D.4
-
193
-
-
25444476685
-
Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody
-
't Hart BA, Brok HP, Remarque E, et al. Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody. J Immunol 2005; 175 (7): 4761-8 (Pubitemid 41362018)
-
(2005)
Journal of Immunology
, vol.175
, Issue.7
, pp. 4761-4768
-
-
'T Hart, B.A.1
Brok, H.P.M.2
Remarque, E.3
Benson, J.4
Treacy, G.5
Amor, S.6
Hintzen, R.Q.7
Laman, J.D.8
Bauer, J.9
Blezer, E.L.A.10
-
194
-
-
0032211092
-
Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis
-
Constantinescu CS, Wysocka M, Hilliard B, et al. Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis. J Immunol 1998; 161 (9): 5097-104 (Pubitemid 28492093)
-
(1998)
Journal of Immunology
, vol.161
, Issue.9
, pp. 5097-5104
-
-
Constantinescu, C.S.1
Wysocka, M.2
Hilliard, B.3
Ventura, E.S.4
Lavi, E.5
Trinchieri, G.6
Rostami, A.7
-
195
-
-
33749031866
-
A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis
-
DOI 10.1185/030079906X120931
-
Kasper LH, Everitt D, Leist TP, et al. A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis. Curr Med Res Opin 2006; 22 (9): 1671-8 (Pubitemid 44449223)
-
(2006)
Current Medical Research and Opinion
, vol.22
, Issue.9
, pp. 1671-1678
-
-
Kasper, L.H.1
Everitt, D.2
Leist, T.P.3
Ryan, K.A.4
Mascelli, M.A.5
Johnson, K.6
Raychaudhuri, A.7
Vollmer, T.8
-
196
-
-
66449113393
-
Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis?
-
Longbrake EE, Racke MK. Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis? Expert Rev Neurother 2009; 9 (3): 319-21
-
(2009)
Expert Rev Neurother
, vol.9
, Issue.3
, pp. 319-21
-
-
Longbrake, E.E.1
Racke, M.K.2
-
197
-
-
0029788704
-
IL-12 unmasks latent autoimmune disease in resistant mice
-
Segal BM, Shevach EM. IL-12 unmasks latent autoimmune disease in resistant mice. J Exp Med 1996; 184 (2): 771-5 (Pubitemid 26324133)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.2
, pp. 771-775
-
-
Segal, B.M.1
Shevach, E.M.2
-
198
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
DOI 10.1038/35010115
-
Gross JA, Johnston J, Mudri S, et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 2000; 404 (6781): 995-9 (Pubitemid 30243593)
-
(2000)
Nature
, vol.404
, Issue.6781
, pp. 995-999
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
Enselman, R.4
Dillon, S.R.5
Madden, K.6
Xu, W.7
Parrish-Novak, J.8
Foster, D.9
Lofton-Day, C.10
Moore, M.11
Littau, A.12
Grossman, A.13
Haugen, H.14
Foley, K.15
Blumberg, H.16
Harrison, K.17
Kindsvogel, W.18
Clegg, C.H.19
-
199
-
-
17944375043
-
TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: Impaired B cell maturation in mice lacking BLyS
-
DOI 10.1016/S1074-7613(01)00183-2
-
Gross JA, Dillon SR, Mudri S, et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS. Immunity 2001; 15 (2): 289-302 (Pubitemid 32816877)
-
(2001)
Immunity
, vol.15
, Issue.2
, pp. 289-302
-
-
Gross, J.A.1
Dillon, S.R.2
Mudri, S.3
Johnston, J.4
Littau, A.5
Roque, R.6
Rixon, M.7
Schou, O.8
Foley, K.P.9
Haugen, H.10
McMillen, S.11
Waggie, K.12
Schreckhise, R.W.13
Shoemaker, K.14
Vu, T.15
Moore, M.16
Grossman, A.17
Clegg, C.H.18
-
200
-
-
0033532634
-
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
-
DOI 10.1084/jem.189.11.1747
-
Schneider P, Mackay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999; 189 (11): 1747-56 (Pubitemid 29272691)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.11
, pp. 1747-1756
-
-
Schneider, P.1
Mackay, F.2
Steiner, V.3
Hofmann, K.4
Bodmer, J.-L.5
Holler, N.6
Ambrose, C.7
Lawton, P.8
Bixler, S.9
Acha-Orbea, H.10
Valmori, D.11
Romero, P.12
Werner-Favre, C.13
Zubler, R.H.14
Browning, J.L.15
Tschopp, J.16
-
201
-
-
18844447818
-
The role of APRIL and BAFF in lymphocyte activation
-
DOI 10.1016/j.coi.2005.04.005, PII S095279150500049X, Lymphocyte Activation/Lymphocyte Effector Functions
-
Schneider P. The role of APRIL and BAFF in lymphocyte activation. Curr Opin Immunol 2005; 17 (3): 282-9 (Pubitemid 40692663)
-
(2005)
Current Opinion in Immunology
, vol.17
, Issue.3
, pp. 282-289
-
-
Schneider, P.1
-
202
-
-
20244384231
-
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
-
DOI 10.1084/jem.20041674
-
Krumbholz M, Theil D, Derfuss T, et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 2005; 201 (2): 195-200 (Pubitemid 40189428)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 195-200
-
-
Krumbholz, M.1
Theil, D.2
Derfuss, T.3
Rosenwald, A.4
Schrader, F.5
Monoranu, C.-M.6
Kalled, S.L.7
Hess, D.M.8
Serafini, B.9
Aloisi, F.10
Wekerle, H.11
Hohlfeld, R.12
Meinl, E.13
-
203
-
-
24144460022
-
Increased levels of APRIL (A Proliferation-Inducing Ligand) mRNA in multiple sclerosis
-
DOI 10.1016/j.jneuroim.2005.06.024, PII S0165572805002754
-
Thangarajh M, Masterman T, Rot U, et al. Increased levels of APRIL (a proliferation-inducing ligand) mRNA in multiple sclerosis. J Neuroimmunol 2005; 167 (1-2): 210-4 (Pubitemid 41242304)
-
(2005)
Journal of Neuroimmunology
, vol.167
, Issue.1-2
, pp. 210-214
-
-
Thangarajh, M.1
Masterman, T.2
Rot, U.3
Duvefelt, K.4
Brynedal, B.5
Karrenbauer, V.D.6
Hillert, J.7
-
204
-
-
0034729769
-
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
-
DOI 10.1016/S0960-9822(00)00566-2
-
Marsters SA, Yan M, Pitti RM, et al. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr Biol 2000; 10 (13): 785-8 (Pubitemid 30466942)
-
(2000)
Current Biology
, vol.10
, Issue.13
, pp. 785-788
-
-
Marsters, S.A.1
Yan, M.2
Pitti, R.M.3
Haas, P.E.4
Dixit, V.M.5
Ashkenazi, A.6
-
205
-
-
37149032474
-
Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial
-
DOI 10.1002/art.23047
-
Dall'Era M, Chakravarty E, Wallace D, et al. Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebocontrolled, dose-escalating trial. Arthritis Rheum 2007; 56 (12): 4142-50 (Pubitemid 350262342)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 4142-4150
-
-
Dall'Era, M.1
Chakravarty, E.2
Wallace, D.3
Genovese, M.4
Weisman, M.5
Kavanaugh, A.6
Kalunian, K.7
Dhar, P.8
Vincent, E.9
Pena-Rossi, C.10
Wofsy, D.11
Alum, N.12
Dubois, A.13
Kinnman, N.14
Picard, M.15
Bortolotti, A.16
O'Grady, L.17
Hill, J.18
Nestorov, I.19
Salmon, E.20
more..
-
206
-
-
16244423682
-
The role of BAFF in immune function and implications for autoimmunity
-
DOI 10.1111/j.0105-2896.2005.00219.x
-
Kalled SL. The role of BAFF in immune function and implications for autoimmunity. Immunol Rev 2005; 204: 43-54 (Pubitemid 40460492)
-
(2005)
Immunological Reviews
, vol.204
, pp. 43-54
-
-
Kalled, S.L.1
-
207
-
-
34250365790
-
Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers
-
DOI 10.1007/s00228-007-0311-7
-
Munafo A, Priestley A, Nestorov I, et al. Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers. Eur J Clin Pharmacol 2007; 63 (7): 647-56 (Pubitemid 46911347)
-
(2007)
European Journal of Clinical Pharmacology
, vol.63
, Issue.7
, pp. 647-656
-
-
Munafo, A.1
Priestley, A.2
Nestorov, I.3
Visich, J.4
Rogge, M.5
-
208
-
-
40749132997
-
Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritis
-
DOI 10.1177/0091270008315312
-
Nestorov I, Munafo A, Papasouliotis O, et al. Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritis. J Clin Pharmacol 2008; 48 (4): 406-17 (Pubitemid 351389119)
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.4
, pp. 406-417
-
-
Nestorov, I.1
Munafo, A.2
Papasouliotis, O.3
Visich, J.4
-
209
-
-
38149114077
-
Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, singleand repeated-dose study
-
Tak PP, ThurlingsRM, Rossier C, et al. Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, singleand repeated-dose study. Arthritis Rheum 2008; 58 (1): 61-72
-
(2008)
Arthritis Rheum
, vol.58
, Issue.1
, pp. 61-72
-
-
Tak, P.P.1
Thurlings, R.M.2
Rossier, C.3
-
210
-
-
65149106325
-
An exploratory dose-escalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus
-
Pena-Rossi C, Nasonov E, Stanislav M, et al. An exploratory dose-escalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus. Lupus 2009; 18 (6): 547-55
-
(2009)
Lupus
, vol.18
, Issue.6
, pp. 547-55
-
-
Pena-Rossi, C.1
Nasonov, E.2
Stanislav, M.3
-
211
-
-
84855763557
-
-
EMD Serono [Clinical Trials.gov identifier NCT00664521] US National Institutes of Health Clinical Trials.gov [online]. Available from URL [Accessed 2011 Jun 30]
-
EMD Serono. Atacicept in combination with rituximab in subjects with rheumatoid arthritis (August III). [Clinical Trials.gov identifier NCT00664521] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2011 Jun 30]
-
Atacicept in Combination with Rituximab in Subjects with Rheumatoid Arthritis (August III)
-
-
-
213
-
-
84892966562
-
-
Eli Lilly and Company [Clinical Trials.gov identifier NCT00882999] US National Institutes of Health Clinical Trials.gov [online]. Available from URL [Accessed 2011 Jun 30]
-
Eli Lilly and Company. A study of patients with relapsing remitting multiple sclerosis. [Clinical Trials.gov identifier NCT00882999] US National Institutes of Health, Clinical Trials.gov [online]. Available from URL: http://www.clini caltrials.gov [Accessed 2011 Jun 30]
-
A Study of Patients with Relapsing Remitting Multiple Sclerosis
-
-
-
214
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
-
Hueber W, Patel DD, Dryja T, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2010; 2 (52): 52ra72
-
(2010)
Sci Transl Med
, vol.2
, Issue.52
-
-
Hueber, W.1
Patel, D.D.2
Dryja, T.3
-
216
-
-
77953563408
-
The complex clinical picture of side effects to biologicals
-
xi-ii
-
Hausmann OV, Seitz M, Villiger PM, et al. The complex clinical picture of side effects to biologicals. Med Clin North Am 2010; 94 (4): 791-804, xi-ii
-
(2010)
Med Clin North Am
, vol.94
, Issue.4
, pp. 791-804
-
-
Hausmann, O.V.1
Seitz, M.2
Villiger, P.M.3
-
217
-
-
0033897315
-
Multiple sklerose. Aktuelle ubersicht zu fehlgeschlagenen und abgebrochenen therapiestudien
-
DOI 10.1007/s001150050636
-
Wiendl H, Neuhaus O, Kappos L, et al. Multiple sclerosis: current review of failed and discontinued clinical trials of drug treatment. Nervenarzt 2000; 71 (8): 597-610 (Pubitemid 30641338)
-
(2000)
Nervenarzt
, vol.71
, Issue.8
, pp. 597-610
-
-
Wiendl, H.1
Neuhaus, O.2
Kappos, L.3
Hohlfeld, R.4
-
218
-
-
0035092524
-
The ups and downs of multiple sclerosis therapeutics
-
DOI 10.1002/ana.61
-
Hohlfeld R, Wiendl H. The ups and downs of multiple sclerosis therapeutics. Ann Neurol 2001; 49 (3): 281-4 (Pubitemid 32202778)
-
(2001)
Annals of Neurology
, vol.49
, Issue.3
, pp. 281-284
-
-
Hohlfeld, R.1
Wiendl, H.2
-
219
-
-
0036022681
-
Therapeutic approaches in multiple sclerosis: Lessons from failed and interrupted treatment trials
-
Wiendl H, Hohlfeld R. Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials. Biodrugs 2002; 16 (3): 183-200 (Pubitemid 34852318)
-
(2002)
BioDrugs
, vol.16
, Issue.3
, pp. 183-200
-
-
Wiendl, H.1
Hohlfeld, R.2
-
220
-
-
76149093586
-
A placebocontrolled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos L, Radue EW, O'Connor P, et al. A placebocontrolled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 2010; 362 (5): 387-401
-
(2010)
N Engl J Med
, vol.362
, Issue.5
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'Connor, P.3
-
221
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010; 362 (5): 402-15
-
(2010)
N Engl J Med
, vol.362
, Issue.5
, pp. 402-15
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
-
222
-
-
45249107267
-
Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study
-
DOI 10.1016/S0140-6736(08)60918-6, PII S0140673608609186
-
Comi G, Pulizzi A, Rovaris M, et al. Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 2008; 371 (9630): 2085-92 (Pubitemid 351842581)
-
(2008)
The Lancet
, vol.371
, Issue.9630
, pp. 2085-2092
-
-
Comi, G.1
Pulizzi, A.2
Rovaris, M.3
Abramsky, O.4
Arbizu, T.5
Boiko, A.6
Gold, R.7
Havrdova, E.8
Komoly, S.9
Selmaj, K.10
Sharrack, B.11
Filippi, M.12
-
223
-
-
54149116366
-
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study
-
Kappos L, Gold R, Miller DH, et al. Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 2008; 372 (9648): 1463-72
-
(2008)
Lancet
, vol.372
, Issue.9648
, pp. 1463-72
-
-
Kappos, L.1
Gold, R.2
Miller, D.H.3
-
224
-
-
79952318554
-
Phase II trial of firategrast shows that oral anti-alpha4 therapy can suppress new MRI lesions in relapsing-remitting multiple sclerosis
-
[abstract no. 113 plus oral presentation] Oct 13-16; Gothenburg
-
Miller D, Weber T, Montalban X, et al. Phase II trial of firategrast shows that oral anti-alpha4 therapy can suppress new MRI lesions in relapsing-remitting multiple sclerosis [abstract no. 113 plus oral presentation]. Presented at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS); 2010 Oct 13-16; Gothenburg
-
(2010)
26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
-
-
Miller, D.1
Weber, T.2
Montalban, X.3
-
225
-
-
33645799680
-
A phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses
-
DOI 10.1212/01.wnl.0000203121.04509.31, PII 0000611420060328000022
-
O'Connor PW, Li D, Freedman MS, et al. A phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses. Neurology 2006; 66 (6): 894-900 (Pubitemid 43739766)
-
(2006)
Neurology
, vol.66
, Issue.6
, pp. 894-900
-
-
O'Connor, P.W.1
Li, D.2
Freedman, M.S.3
Bar-Or, A.4
Rice, G.P.A.5
Confavreux, C.6
Paty, D.W.7
Stewart, J.A.8
Scheyer, R.9
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