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Volumn 117, Issue 3, 2005, Pages 207-213

The therapeutic potential of anti-CD20: What do B-cells do?

Author keywords

B cells; CD20; Rituximab

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; CD20 ANTIBODY; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; RITUXIMAB; STEROID;

EID: 29344460633     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2005.08.006     Document Type: Review
Times cited : (120)

References (101)
  • 1
    • 0037819344 scopus 로고    scopus 로고
    • An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab
    • J. Boye, T. Elter, and A. Engert An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab Ann. Oncol. 14 4 2003 520 535
    • (2003) Ann. Oncol. , vol.14 , Issue.4 , pp. 520-535
    • Boye, J.1    Elter, T.2    Engert, A.3
  • 2
    • 0042173008 scopus 로고    scopus 로고
    • SLE-Rituximab in lupus
    • R. Eisenberg SLE-Rituximab in lupus Arthritis Res. Ther. 5 4 2003 157 159
    • (2003) Arthritis Res. Ther. , vol.5 , Issue.4 , pp. 157-159
    • Eisenberg, R.1
  • 3
    • 0037638841 scopus 로고    scopus 로고
    • Rituximab therapy and autoimmune disorders: Prospects for anti-B cell therapy
    • G.J. Silverman, and S. Weisman Rituximab therapy and autoimmune disorders: prospects for anti-B cell therapy Arthritis Rheum. 48 6 2003 1484 1492
    • (2003) Arthritis Rheum. , vol.48 , Issue.6 , pp. 1484-1492
    • Silverman, G.J.1    Weisman, S.2
  • 4
    • 0036993543 scopus 로고    scopus 로고
    • Effective B cell depletion with rituximab in the treatment of autoimmune diseases
    • C. Kneitz, M. Wilhelm, and H.P. Tony Effective B cell depletion with rituximab in the treatment of autoimmune diseases Immunobiology 206 5 2002 519 527
    • (2002) Immunobiology , vol.206 , Issue.5 , pp. 519-527
    • Kneitz, C.1    Wilhelm, M.2    Tony, H.P.3
  • 5
    • 0036785369 scopus 로고    scopus 로고
    • Treating human autoimmune disease by depleting B cells
    • R.J. Looney Treating human autoimmune disease by depleting B cells Ann. Rheum. Dis. 61 10 2002 863 866 (comment)
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.10 , pp. 863-866
    • Looney, R.J.1
  • 6
    • 0042236333 scopus 로고    scopus 로고
    • Rituximab in B-cell chronic lymphocytic leukemia
    • T.S. Lin, M.S. Lucas, and J.C. Byrd Rituximab in B-cell chronic lymphocytic leukemia Semin. Oncol. 30 4 2003 483 492
    • (2003) Semin. Oncol. , vol.30 , Issue.4 , pp. 483-492
    • Lin, T.S.1    Lucas, M.S.2    Byrd, J.C.3
  • 7
    • 27744501244 scopus 로고    scopus 로고
    • B cells as a therapeutic target in autoimmune diseases other than rheumatoid arthritis
    • R.J. Looney B cells as a therapeutic target in autoimmune diseases other than rheumatoid arthritis Rheumatology (Oxford) 44 Suppl. 2 2005 ii13 ii17
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.SUPPL. 2
    • Looney, R.J.1
  • 8
    • 21644448329 scopus 로고    scopus 로고
    • B cell targeted therapies
    • E. Keystone B cell targeted therapies Arthritis Res. Ther. 7 Suppl. 3 2005 S13 S18
    • (2005) Arthritis Res. Ther. , vol.7 , Issue.SUPPL. 3
    • Keystone, E.1
  • 9
    • 16544389341 scopus 로고    scopus 로고
    • The biology of CD20 and its potential as a target for mAb therapy
    • M.S. Cragg The biology of CD20 and its potential as a target for mAb therapy Curr. Dir. Autoimmun 8 2005 140 174
    • (2005) Curr. Dir. Autoimmun , vol.8 , pp. 140-174
    • Cragg, M.S.1
  • 10
    • 15944368138 scopus 로고    scopus 로고
    • Anti-B cell therapy (rituximab) in the treatment of autoimmune diseases
    • S.A. Chambers, and D. Isenberg Anti-B cell therapy (rituximab) in the treatment of autoimmune diseases Lupus 14 3 2005 210 214
    • (2005) Lupus , vol.14 , Issue.3 , pp. 210-214
    • Chambers, S.A.1    Isenberg, D.2
  • 11
    • 0842348219 scopus 로고    scopus 로고
    • Role of anti-CD20 monoclonal antibody in association with immunomodulatory agents
    • A. Bosly Role of anti-CD20 monoclonal antibody in association with immunomodulatory agents Pathol. Biol. (Paris) 52 1 2004 39 42
    • (2004) Pathol. Biol. (Paris) , vol.52 , Issue.1 , pp. 39-42
    • Bosly, A.1
  • 12
    • 0037251878 scopus 로고    scopus 로고
    • Rituximab: A review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
    • G.L. Plosker, and D.P. Figgitt Rituximab: a review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia Drugs 63 8 2003 803 843
    • (2003) Drugs , vol.63 , Issue.8 , pp. 803-843
    • Plosker, G.L.1    Figgitt, D.P.2
  • 13
    • 1542358942 scopus 로고    scopus 로고
    • Rituximab: Expanding role in therapy for lymphomas and autoimmune diseases
    • W. Rastetter, A. Molina, and C.A. White Rituximab: expanding role in therapy for lymphomas and autoimmune diseases Annu. Rev. Med. 55 2004 477 503
    • (2004) Annu. Rev. Med. , vol.55 , pp. 477-503
    • Rastetter, W.1    Molina, A.2    White, C.A.3
  • 14
    • 0023976470 scopus 로고
    • Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains
    • D.A. Einfeld Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains EMBO J. 7 3 1988 711 717
    • (1988) EMBO J. , vol.7 , Issue.3 , pp. 711-717
    • Einfeld, D.A.1
  • 15
    • 0023672444 scopus 로고
    • Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes
    • T.F. Tedder Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes Proc. Natl. Acad. Sci. U. S. A. 85 1 1988 208 212
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , Issue.1 , pp. 208-212
    • Tedder, T.F.1
  • 16
    • 0036566507 scopus 로고    scopus 로고
    • Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; Heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure
    • M.J. Polyak, and J.P. Deans Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure Blood 99 9 2002 3256 3262
    • (2002) Blood , vol.99 , Issue.9 , pp. 3256-3262
    • Polyak, M.J.1    Deans, J.P.2
  • 17
    • 0024410224 scopus 로고
    • Phosphorylation of the CD20 phosphoprotein in resting B lymphocytes. Regulation by protein kinase C
    • M.A. Valentine Phosphorylation of the CD20 phosphoprotein in resting B lymphocytes. Regulation by protein kinase C J. Biol. Chem. 264 19 1989 11282 11287
    • (1989) J. Biol. Chem. , vol.264 , Issue.19 , pp. 11282-11287
    • Valentine, M.A.1
  • 18
    • 0027168420 scopus 로고
    • Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes
    • J.K. Bubien Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes J. Cell Biol. 121 5 1993 1121 1132
    • (1993) J. Cell Biol. , vol.121 , Issue.5 , pp. 1121-1132
    • Bubien, J.K.1
  • 19
    • 0027184419 scopus 로고
    • Phosphorylation of CD20 in cells from a hairy cell leukemia cell line. Evidence for involvement of calcium/calmodulin-dependent protein kinase II
    • E.M. Genot Phosphorylation of CD20 in cells from a hairy cell leukemia cell line. Evidence for involvement of calcium/calmodulin-dependent protein kinase II J. Immunol. 151 1 1993 71 82
    • (1993) J. Immunol. , vol.151 , Issue.1 , pp. 71-82
    • Genot, E.M.1
  • 20
    • 0031918984 scopus 로고    scopus 로고
    • B cell maturation and selection at the marrow-periphery interface
    • M.P. Cancro B cell maturation and selection at the marrow-periphery interface Immunol. Res. 17 1-2 1998 3 11
    • (1998) Immunol. Res. , vol.17 , Issue.1-2 , pp. 3-11
    • Cancro, M.P.1
  • 21
    • 0027316197 scopus 로고
    • Phenotypic difference of normal plasma cells from mature myeloma cells
    • H. Harada Phenotypic difference of normal plasma cells from mature myeloma cells Blood 81 10 1993 2658 2663
    • (1993) Blood , vol.81 , Issue.10 , pp. 2658-2663
    • Harada, H.1
  • 22
    • 0036140240 scopus 로고    scopus 로고
    • CD20-directed serotherapy in patients with multiple myeloma: Biologic considerations and therapeutic applications
    • S.P. Treon CD20-directed serotherapy in patients with multiple myeloma: biologic considerations and therapeutic applications J. Immunother. 25 1 2002 72 81
    • (2002) J. Immunother. , vol.25 , Issue.1 , pp. 72-81
    • Treon, S.P.1
  • 23
    • 0024239150 scopus 로고
    • Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19
    • T.F. Tedder Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19 J. Immunol. 141 12 1988 4388 4394
    • (1988) J. Immunol. , vol.141 , Issue.12 , pp. 4388-4394
    • Tedder, T.F.1
  • 24
    • 0031813122 scopus 로고    scopus 로고
    • Mice carrying a CD20 gene disruption
    • T.L. O'Keefe Mice carrying a CD20 gene disruption Immunogenetics 48 2 1998 125 132
    • (1998) Immunogenetics , vol.48 , Issue.2 , pp. 125-132
    • O'Keefe, T.L.1
  • 25
    • 0031837813 scopus 로고    scopus 로고
    • Levels of expression of CD19 and CD20 in chronic B cell leukaemias
    • L. Ginaldi Levels of expression of CD19 and CD20 in chronic B cell leukaemias J. Clin. Pathol. 51 5 1998 364 369
    • (1998) J. Clin. Pathol. , vol.51 , Issue.5 , pp. 364-369
    • Ginaldi, L.1
  • 26
    • 19944427673 scopus 로고    scopus 로고
    • Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy
    • Q. Gong Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy J. Immunol. 174 2 2005 817 826
    • (2005) J. Immunol. , vol.174 , Issue.2 , pp. 817-826
    • Gong, Q.1
  • 27
    • 15444368773 scopus 로고    scopus 로고
    • The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice
    • Y. Hamaguchi The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice J. Immunol. 174 7 2005 4389 4399
    • (2005) J. Immunol. , vol.174 , Issue.7 , pp. 4389-4399
    • Hamaguchi, Y.1
  • 28
    • 0032740187 scopus 로고    scopus 로고
    • Overview of the clinical development of rituximab: First monoclonal antibody approved for the treatment of lymphoma
    • A.J. Grillo-Lopez Overview of the clinical development of rituximab: first monoclonal antibody approved for the treatment of lymphoma Semin. Oncol. 26 5 Suppl. 14 1999 66 73
    • (1999) Semin. Oncol. , vol.26 , Issue.5 SUPPL. 14 , pp. 66-73
    • Grillo-Lopez, A.J.1
  • 29
    • 0034468346 scopus 로고    scopus 로고
    • Rituximab: An insider's historical perspective
    • A.J. Grillo-Lopez Rituximab: an insider's historical perspective Semin. Oncol. 27 6 Suppl. 12 2000 9 16
    • (2000) Semin. Oncol. , vol.27 , Issue.6 SUPPL. 12 , pp. 9-16
    • Grillo-Lopez, A.J.1
  • 30
    • 0034467186 scopus 로고    scopus 로고
    • Chemotherapy sensitization by rituximab: Experimental and clinical evidence
    • W.H. Wilson Chemotherapy sensitization by rituximab: experimental and clinical evidence Semin. Oncol. 27 6 Suppl. 12 2000 30 36
    • (2000) Semin. Oncol. , vol.27 , Issue.6 SUPPL. 12 , pp. 30-36
    • Wilson, W.H.1
  • 31
    • 0034951864 scopus 로고    scopus 로고
    • Mechanism of action of rituximab
    • D.G. Maloney Mechanism of action of rituximab Anticancer Drugs 12 Suppl. 2 2001 S1 S4
    • (2001) Anticancer Drugs , vol.12 , Issue.SUPPL. 2
    • Maloney, D.G.1
  • 32
    • 0036877336 scopus 로고    scopus 로고
    • Mechanism of action of rituximab
    • T. Cerny Mechanism of action of rituximab Anticancer Drugs 13 Suppl. 2 2002 S3 S10
    • (2002) Anticancer Drugs , vol.13 , Issue.SUPPL. 2
    • Cerny, T.1
  • 33
    • 20944442617 scopus 로고    scopus 로고
    • Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis
    • Y. Vugmeyster Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis J. Immunother. 28 3 2005 212 219
    • (2005) J. Immunother. , vol.28 , Issue.3 , pp. 212-219
    • Vugmeyster, Y.1
  • 34
    • 18744405710 scopus 로고    scopus 로고
    • Humanized anti-CD20 monoclonal antibody in the treatment of severe resistant systemic lupus erythematosus in a patient with antibodies against rituximab
    • H. Tahir Humanized anti-CD20 monoclonal antibody in the treatment of severe resistant systemic lupus erythematosus in a patient with antibodies against rituximab Rheumatology (Oxford) 44 4 2005 561 562
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.4 , pp. 561-562
    • Tahir, H.1
  • 35
    • 0034796371 scopus 로고    scopus 로고
    • Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone
    • N. Di Gaetano Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone Br. J. Haematol. 114 4 2001 800 809
    • (2001) Br. J. Haematol. , vol.114 , Issue.4 , pp. 800-809
    • Di Gaetano, N.1
  • 36
    • 0035393595 scopus 로고    scopus 로고
    • Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs
    • S. Alas, and B. Bonavida Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs Cancer Res. 61 13 2001 5137 5144
    • (2001) Cancer Res. , vol.61 , Issue.13 , pp. 5137-5144
    • Alas, S.1    Bonavida, B.2
  • 37
    • 0034104375 scopus 로고    scopus 로고
    • Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
    • D. Shan, J.A. Ledbetter, and O.W. Press Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells Cancer Immunol. Immunother. 48 12 2000 673 683
    • (2000) Cancer Immunol. Immunother. , vol.48 , Issue.12 , pp. 673-683
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 38
    • 0033794618 scopus 로고    scopus 로고
    • Potentiation of fludarabine cytotoxicity on non-Hodgkin's lymphoma by pentoxifylline and rituximab
    • S. Alas, B. Bonavida, and C. Emmanouilides Potentiation of fludarabine cytotoxicity on non-Hodgkin's lymphoma by pentoxifylline and rituximab Anticancer Res. 20 5A 2000 2961 2966
    • (2000) Anticancer Res. , vol.20 , Issue.5 A , pp. 2961-2966
    • Alas, S.1    Bonavida, B.2    Emmanouilides, C.3
  • 39
    • 0034091481 scopus 로고    scopus 로고
    • Rituximab (anti-CD20) therapy of B-cell lymphomas: Direct complement killing is superior to cellular effector mechanisms
    • A. Harjunpaa, S. Junnikkala, and S. Meri Rituximab (anti-CD20) therapy of B-cell lymphomas: direct complement killing is superior to cellular effector mechanisms Scand. J. Immunol. 51 6 2000 634 641
    • (2000) Scand. J. Immunol. , vol.51 , Issue.6 , pp. 634-641
    • Harjunpaa, A.1    Junnikkala, S.2    Meri, S.3
  • 40
    • 0033855194 scopus 로고    scopus 로고
    • Clustered CD20 induced apoptosis: Src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis
    • J.K. Hofmeister, D. Cooney, and K.M. Coggeshall Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis Blood Cells Mol. Diseases 26 2 2000 133 143
    • (2000) Blood Cells Mol. Diseases , vol.26 , Issue.2 , pp. 133-143
    • Hofmeister, J.K.1    Cooney, D.2    Coggeshall, K.M.3
  • 41
    • 0037452616 scopus 로고    scopus 로고
    • Variation in gene expression patterns in follicular lymphoma and the response to rituximab
    • S.P. Bohen Variation in gene expression patterns in follicular lymphoma and the response to rituximab Proc. Natl. Acad. Sci. U. S. A. 100 4 2003 1926 1930
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.4 , pp. 1926-1930
    • Bohen, S.P.1
  • 42
    • 3042743884 scopus 로고    scopus 로고
    • Rituximab-dependent cytotoxicity by natural killer cells: Influence of FCGR3A polymorphism on the concentration-effect relationship
    • S. Dall'Ozzo Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship Cancer Res. 64 13 2004 4664 4669
    • (2004) Cancer Res. , vol.64 , Issue.13 , pp. 4664-4669
    • Dall'Ozzo, S.1
  • 43
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
    • G. Cartron Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene Blood 99 3 2002 754 758
    • (2002) Blood , vol.99 , Issue.3 , pp. 754-758
    • Cartron, G.1
  • 45
    • 0035469885 scopus 로고    scopus 로고
    • Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non-Hodgkin lymphoma
    • W.K. Weng, and R. Levy Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non-Hodgkin lymphoma Blood 98 5 2001 1352 1357
    • (2001) Blood , vol.98 , Issue.5 , pp. 1352-1357
    • Weng, W.K.1    Levy, R.2
  • 46
    • 0034999619 scopus 로고    scopus 로고
    • Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies
    • S.P. Treon Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies J. Immunother. 24 3 2001 263 271
    • (2001) J. Immunother. , vol.24 , Issue.3 , pp. 263-271
    • Treon, S.P.1
  • 47
    • 0034660092 scopus 로고    scopus 로고
    • Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis
    • J. Golay Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis Blood 95 12 2000 3900 3908
    • (2000) Blood , vol.95 , Issue.12 , pp. 3900-3908
    • Golay, J.1
  • 48
    • 0037306946 scopus 로고    scopus 로고
    • Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts
    • M.S. Cragg Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts Blood 101 3 2003 1045 1052
    • (2003) Blood , vol.101 , Issue.3 , pp. 1045-1052
    • Cragg, M.S.1
  • 49
    • 0036408912 scopus 로고    scopus 로고
    • CD20-mediated apoptosis: Signalling through lipid rafts
    • J.P. Deans, H. Li, and M.J. Polyak CD20-mediated apoptosis: signalling through lipid rafts Immunology 107 2 2002 176 182
    • (2002) Immunology , vol.107 , Issue.2 , pp. 176-182
    • Deans, J.P.1    Li, H.2    Polyak, M.J.3
  • 50
    • 3843139379 scopus 로고    scopus 로고
    • Rituximab antiproliferative effect in B-lymphoma cells is associated with acid-sphingomyelinase activation in raft microdomains
    • C. Bezombes Rituximab antiproliferative effect in B-lymphoma cells is associated with acid-sphingomyelinase activation in raft microdomains Blood 104 4 2004 1166 1173
    • (2004) Blood , vol.104 , Issue.4 , pp. 1166-1173
    • Bezombes, C.1
  • 51
    • 0034890639 scopus 로고    scopus 로고
    • Synergistic effects of the fenretinide (4-hpr) and anti-cd20 monoclonal antibodies on apoptosis induction of malignant human b cells
    • D. Shan, A.K. Gopal, and O.W. Press Synergistic effects of the fenretinide (4-hpr) and anti-cd20 monoclonal antibodies on apoptosis induction of malignant human b cells Clin. Cancer Res. 7 8 2001 2490 2495
    • (2001) Clin. Cancer Res. , vol.7 , Issue.8 , pp. 2490-2495
    • Shan, D.1    Gopal, A.K.2    Press, O.W.3
  • 52
    • 0034469621 scopus 로고    scopus 로고
    • Safety of fludarabine, mitoxantrone, and dexamethasone combined with rituximab in the treatment of stage IV indolent lymphoma
    • P. McLaughlin Safety of fludarabine, mitoxantrone, and dexamethasone combined with rituximab in the treatment of stage IV indolent lymphoma Semin. Oncol. 27 6 Suppl. 12 2000 37 41
    • (2000) Semin. Oncol. , vol.27 , Issue.6 SUPPL. 12 , pp. 37-41
    • McLaughlin, P.1
  • 53
    • 0032719758 scopus 로고    scopus 로고
    • Rituximab in indolent lymphoma: The single-agent pivotal trial
    • P. McLaughlin, F.B. Hagemeister, and A.J. Grillo-Lopez Rituximab in indolent lymphoma: the single-agent pivotal trial Semin. Oncol. 26 5 Suppl. 14 1999 79 87
    • (1999) Semin. Oncol. , vol.26 , Issue.5 SUPPL. 14 , pp. 79-87
    • McLaughlin, P.1    Hagemeister, F.B.2    Grillo-Lopez, A.J.3
  • 54
    • 16544374958 scopus 로고    scopus 로고
    • B lymphocyte depletion in rheumatoid arthritis: Targeting of CD20
    • J.C. Edwards, M.J. Leandro, and G. Cambridge B lymphocyte depletion in rheumatoid arthritis: targeting of CD20 Curr. Dir. Autoimmun. 8 2005 175 192
    • (2005) Curr. Dir. Autoimmun. , vol.8 , pp. 175-192
    • Edwards, J.C.1    Leandro, M.J.2    Cambridge, G.3
  • 56
    • 14044279959 scopus 로고    scopus 로고
    • Prospects for B-cell-targeted therapy in autoimmune disease
    • J.C. Edwards, and G. Cambridge Prospects for B-cell-targeted therapy in autoimmune disease Rheumatology (Oxford) 44 2 2005 151 156
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.2 , pp. 151-156
    • Edwards, J.C.1    Cambridge, G.2
  • 57
    • 0032791210 scopus 로고    scopus 로고
    • Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma
    • L.D. Piro Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma Ann. Oncol. 10 6 1999 655 661
    • (1999) Ann. Oncol. , vol.10 , Issue.6 , pp. 655-661
    • Piro, L.D.1
  • 58
    • 0035406003 scopus 로고    scopus 로고
    • Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody
    • T. Maeda Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody Int. J. Hematol. 74 1 2001 70 75
    • (2001) Int. J. Hematol. , vol.74 , Issue.1 , pp. 70-75
    • Maeda, T.1
  • 59
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab
    • R.J. Looney B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab Arthritis Rheum. 50 8 2004 2580 2589
    • (2004) Arthritis Rheum. , vol.50 , Issue.8 , pp. 2580-2589
    • Looney, R.J.1
  • 60
    • 29344471967 scopus 로고    scopus 로고
    • A longitudinal analysis of SLE patients treated with rituximab: A comparison of B cell depleters to partial B cell depleters
    • J. Dunham A longitudinal analysis of SLE patients treated with rituximab: a comparison of B cell depleters to partial B cell depleters Arthritis Rheum. 52 9 Suppl. 2005 S740
    • (2005) Arthritis Rheum. , vol.52 , Issue.9 SUPPL. , pp. 740
    • Dunham, J.1
  • 61
    • 0037289807 scopus 로고    scopus 로고
    • The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus
    • J.H. Anolik The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus Arthritis Rheum. 48 2 2003 455 459
    • (2003) Arthritis Rheum. , vol.48 , Issue.2 , pp. 455-459
    • Anolik, J.H.1
  • 62
    • 10744224469 scopus 로고    scopus 로고
    • B-cell compartment as the selective target for the treatment of immune thrombocytopenias
    • F. Zaja B-cell compartment as the selective target for the treatment of immune thrombocytopenias Haematologica 88 5 2003 538 546
    • (2003) Haematologica , vol.88 , Issue.5 , pp. 538-546
    • Zaja, F.1
  • 63
    • 0038090630 scopus 로고    scopus 로고
    • Immune and cell therapy of hematologic malignancies
    • T.J. Kipps Immune and cell therapy of hematologic malignancies Int. J. Hematol. 76 Suppl. 1 2002 269 273
    • (2002) Int. J. Hematol. , vol.76 , Issue.SUPPL. 1 , pp. 269-273
    • Kipps, T.J.1
  • 64
    • 17844402696 scopus 로고    scopus 로고
    • Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: Depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody
    • I.P. Alwayn Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody Xenotransplantation 8 3 2001 157 171
    • (2001) Xenotransplantation , vol.8 , Issue.3 , pp. 157-171
    • Alwayn, I.P.1
  • 65
    • 0033490211 scopus 로고    scopus 로고
    • Lymphoid aggregates in bone marrow mimic residual lymphoma after rituximab therapy for non-Hodgkin lymphoma
    • V.K. Douglas Lymphoid aggregates in bone marrow mimic residual lymphoma after rituximab therapy for non-Hodgkin lymphoma Am. J. Clin. Pathol. 112 6 1999 844 853
    • (1999) Am. J. Clin. Pathol. , vol.112 , Issue.6 , pp. 844-853
    • Douglas, V.K.1
  • 66
    • 0033067232 scopus 로고    scopus 로고
    • Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: Results of a phase II trial of rituximab
    • T.A. Davis Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: results of a phase II trial of rituximab J. Clin. Oncol. 17 6 1999 1851 1857
    • (1999) J. Clin. Oncol. , vol.17 , Issue.6 , pp. 1851-1857
    • Davis, T.A.1
  • 67
    • 11844258256 scopus 로고    scopus 로고
    • Rituximab inhibits the in vivo primary and secondary antibody response to a neoantigen, bacteriophage phiX174
    • C.M. Bearden Rituximab inhibits the in vivo primary and secondary antibody response to a neoantigen, bacteriophage phiX174 Am. J. Transp. 5 1 2005 50 57
    • (2005) Am. J. Transp. , vol.5 , Issue.1 , pp. 50-57
    • Bearden, C.M.1
  • 68
    • 0035122440 scopus 로고    scopus 로고
    • Hapten-induced primary and memory humoral responses are inhibited by the infusion of anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab)
    • G.V. Gonzalez-Stawinski Hapten-induced primary and memory humoral responses are inhibited by the infusion of anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) Clin. Immunol. 98 2 2001 175 179
    • (2001) Clin. Immunol. , vol.98 , Issue.2 , pp. 175-179
    • Gonzalez-Stawinski, G.V.1
  • 69
    • 0041571732 scopus 로고    scopus 로고
    • Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis
    • G. Cambridge Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis Arthritis Rheum. 48 8 2003 2146 2154
    • (2003) Arthritis Rheum. , vol.48 , Issue.8 , pp. 2146-2154
    • Cambridge, G.1
  • 70
    • 0033549067 scopus 로고    scopus 로고
    • IgM antibody-related polyneuropathies: B-cell depletion chemotherapy using rituximab
    • T.D. Levine, and A. Pestronk IgM antibody-related polyneuropathies: B-cell depletion chemotherapy using rituximab Neurology 52 8 1999 1701 1704
    • (1999) Neurology , vol.52 , Issue.8 , pp. 1701-1704
    • Levine, T.D.1    Pestronk, A.2
  • 71
    • 12344330217 scopus 로고    scopus 로고
    • Induction of remission by B lymphocyte depletion in eleven patients with refractory antineutrophil cytoplasmic antibody-associated vasculitis
    • K.A. Keogh Induction of remission by B lymphocyte depletion in eleven patients with refractory antineutrophil cytoplasmic antibody-associated vasculitis Arthritis Rheum. 52 1 2005 262 268
    • (2005) Arthritis Rheum. , vol.52 , Issue.1 , pp. 262-268
    • Keogh, K.A.1
  • 72
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
    • P.E. Lipsky Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity Nat. Immunol. 2 9 2001 764 766
    • (2001) Nat. Immunol. , vol.2 , Issue.9 , pp. 764-766
    • Lipsky, P.E.1
  • 73
    • 13444252282 scopus 로고    scopus 로고
    • Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: An open-label trial
    • P.P. Sfikakis Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial Arthritis Rheum. 52 2 2005 501 513
    • (2005) Arthritis Rheum. , vol.52 , Issue.2 , pp. 501-513
    • Sfikakis, P.P.1
  • 74
    • 0035888030 scopus 로고    scopus 로고
    • T cell activation in rheumatoid synovium is B cell dependent
    • S. Takemura T cell activation in rheumatoid synovium is B cell dependent J. Immunol. 167 8 2001 4710 4718
    • (2001) J. Immunol. , vol.167 , Issue.8 , pp. 4710-4718
    • Takemura, S.1
  • 75
    • 0033214207 scopus 로고    scopus 로고
    • Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8)
    • U. Winkler Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8) Blood 94 7 1999 2217 2224
    • (1999) Blood , vol.94 , Issue.7 , pp. 2217-2224
    • Winkler, U.1
  • 76
    • 0033506258 scopus 로고    scopus 로고
    • Infusion reactions associated with the therapeutic use of monoclonal antibodies in the treatment of malignancy
    • R.O. Dillman Infusion reactions associated with the therapeutic use of monoclonal antibodies in the treatment of malignancy Cancer Metastasis Rev. 18 4 1999 465 471
    • (1999) Cancer Metastasis Rev. , vol.18 , Issue.4 , pp. 465-471
    • Dillman, R.O.1
  • 77
    • 0034940417 scopus 로고    scopus 로고
    • Serum sickness secondary to treatment with the murine-human chimeric antibody IDEC-C2B8 (rituximab)
    • C.A. D'Arcy, and M. Mannik Serum sickness secondary to treatment with the murine-human chimeric antibody IDEC-C2B8 (rituximab) Arthritis Rheum. 44 7 2001 1717 1718
    • (2001) Arthritis Rheum. , vol.44 , Issue.7 , pp. 1717-1718
    • D'Arcy, C.A.1    Mannik, M.2
  • 78
    • 0038386557 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab, a B-cell targeted chimeric monoclonal antibody: A randomized, placebo-controlled trial in patients with rheumatoid arthritis
    • J.C.W. Edwards Efficacy and safety of rituximab, a B-cell targeted chimeric monoclonal antibody: a randomized, placebo-controlled trial in patients with rheumatoid arthritis Arthritis Rheum. 46 9 2002 S197 (abstract)
    • (2002) Arthritis Rheum. , vol.46 , Issue.9 , pp. 197
    • Edwards, J.C.W.1
  • 79
    • 2942537697 scopus 로고    scopus 로고
    • Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
    • J.C. Edwards Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis N. Engl. J. Med. 350 25 2004 2572 2581
    • (2004) N. Engl. J. Med. , vol.350 , Issue.25 , pp. 2572-2581
    • Edwards, J.C.1
  • 80
    • 0034889699 scopus 로고    scopus 로고
    • Lymphoma in a patient with rheumatoid arthritis receiving methotrexate treatment: Successful treatment with rituximab
    • M. Stewart Lymphoma in a patient with rheumatoid arthritis receiving methotrexate treatment: successful treatment with rituximab Ann. Rheum. Dis. 60 9 2001 892 893
    • (2001) Ann. Rheum. Dis. , vol.60 , Issue.9 , pp. 892-893
    • Stewart, M.1
  • 81
    • 0036785351 scopus 로고    scopus 로고
    • Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion
    • M.J. Leandro, J.C. Edwards, and G. Cambridge Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion Ann. Rheum. Dis. 61 10 2002 883 888
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.10 , pp. 883-888
    • Leandro, M.J.1    Edwards, J.C.2    Cambridge, G.3
  • 82
    • 0036676817 scopus 로고    scopus 로고
    • Efficacy of selective B cell blockade in the treatment of rheumatoid arthritis: Evidence for a pathogenetic role of B cells
    • S. De Vita Efficacy of selective B cell blockade in the treatment of rheumatoid arthritis: evidence for a pathogenetic role of B cells Arthritis Rheum. 46 8 2002 2029 2033
    • (2002) Arthritis Rheum. , vol.46 , Issue.8 , pp. 2029-2033
    • De Vita, S.1
  • 83
    • 0036796978 scopus 로고    scopus 로고
    • Long-term remission of an EBV-positive B cell lymphoproliferative disorder associated with rheumatoid arthritis under methotrexate with anti-CD20 monoclonal antibody (rituximab) monotherapy
    • C. Kelaidi Long-term remission of an EBV-positive B cell lymphoproliferative disorder associated with rheumatoid arthritis under methotrexate with anti-CD20 monoclonal antibody (rituximab) monotherapy Leukemia 16 10 2002 2173 2174
    • (2002) Leukemia , vol.16 , Issue.10 , pp. 2173-2174
    • Kelaidi, C.1
  • 84
    • 0034468410 scopus 로고    scopus 로고
    • A pilot study of the anti-CD20 monoclonal antibody rituximab in patients with refractory immune thrombocytopenia
    • M.N. Saleh A pilot study of the anti-CD20 monoclonal antibody rituximab in patients with refractory immune thrombocytopenia Semin. Oncol. 27 6 Suppl. 12 2000 99 103
    • (2000) Semin. Oncol. , vol.27 , Issue.6 SUPPL. 12 , pp. 99-103
    • Saleh, M.N.1
  • 85
    • 0034940321 scopus 로고    scopus 로고
    • Treatment of refractory autoimmune haemolytic anaemia with anti-CD20 (rituximab)
    • N. Ahrens Treatment of refractory autoimmune haemolytic anaemia with anti-CD20 (rituximab) Br. J. Haematol. 114 1 2001 244 245
    • (2001) Br. J. Haematol. , vol.114 , Issue.1 , pp. 244-245
    • Ahrens, N.1
  • 86
    • 0036822286 scopus 로고    scopus 로고
    • An open study of B lymphocyte depletion in systemic lupus erythematosus
    • M.J. Leandro An open study of B lymphocyte depletion in systemic lupus erythematosus Arthritis Rheum. 46 10 2002 2673 2677
    • (2002) Arthritis Rheum. , vol.46 , Issue.10 , pp. 2673-2677
    • Leandro, M.J.1
  • 87
    • 0034999927 scopus 로고    scopus 로고
    • CD20-directed antibody-mediated immunotherapy induces responses and facilitates hematologic recovery in patients with Waldenstrom's macroglobulinemia
    • S.P. Treon CD20-directed antibody-mediated immunotherapy induces responses and facilitates hematologic recovery in patients with Waldenstrom's macroglobulinemia J. Immunother. 24 3 2001 272 279
    • (2001) J. Immunother. , vol.24 , Issue.3 , pp. 272-279
    • Treon, S.P.1
  • 88
    • 13444278506 scopus 로고    scopus 로고
    • Rituximab in the treatment of dermatomyositis: An open-label pilot study
    • T.D. Levine Rituximab in the treatment of dermatomyositis: an open-label pilot study Arthritis Rheum. 52 2 2005 601 607
    • (2005) Arthritis Rheum. , vol.52 , Issue.2 , pp. 601-607
    • Levine, T.D.1
  • 89
    • 0035691927 scopus 로고    scopus 로고
    • Monotherapy with rituximab induces rapid remission of recurrent cold agglutinin-mediated hemolytic anemia in a patient with indolent lympho-plasmacytic lymphoma
    • Y. Cohen Monotherapy with rituximab induces rapid remission of recurrent cold agglutinin-mediated hemolytic anemia in a patient with indolent lympho-plasmacytic lymphoma Leuk. Lymphoma 42 6 2001 1405 1408
    • (2001) Leuk. Lymphoma , vol.42 , Issue.6 , pp. 1405-1408
    • Cohen, Y.1
  • 90
    • 0034783228 scopus 로고    scopus 로고
    • Favourable response to therapy with the anti-CD20 monoclonal antibody rituximab in primary chronic cold agglutinin disease
    • S. Berentsen Favourable response to therapy with the anti-CD20 monoclonal antibody rituximab in primary chronic cold agglutinin disease Br. J. Haematol. 115 1 2001 79 83
    • (2001) Br. J. Haematol. , vol.115 , Issue.1 , pp. 79-83
    • Berentsen, S.1
  • 91
    • 0036180868 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody (Rituximab) for life-threatening autoimmune haemolytic anaemia in a patient with systemic lupus erythematosus
    • S. Perrotta Anti-CD20 monoclonal antibody (Rituximab) for life-threatening autoimmune haemolytic anaemia in a patient with systemic lupus erythematosus Br. J. Haematol. 116 2 2002 465 467
    • (2002) Br. J. Haematol. , vol.116 , Issue.2 , pp. 465-467
    • Perrotta, S.1
  • 92
    • 0035674612 scopus 로고    scopus 로고
    • Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy
    • U. Specks Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy Arthritis Rheum. 44 12 2001 2836 2840
    • (2001) Arthritis Rheum. , vol.44 , Issue.12 , pp. 2836-2840
    • Specks, U.1
  • 93
    • 0035877988 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody for the treatment of severe, immune-mediated, pure red cell aplasia and hemolytic anemia
    • M. Zecca Anti-CD20 monoclonal antibody for the treatment of severe, immune-mediated, pure red cell aplasia and hemolytic anemia Blood 97 12 2001 3995 3997
    • (2001) Blood , vol.97 , Issue.12 , pp. 3995-3997
    • Zecca, M.1
  • 94
    • 0037152082 scopus 로고    scopus 로고
    • Rituximab for idiopathic membranous nephropathy
    • G. Remuzzi Rituximab for idiopathic membranous nephropathy Lancet 360 9337 2002 923 924
    • (2002) Lancet , vol.360 , Issue.9337 , pp. 923-924
    • Remuzzi, G.1
  • 95
    • 0037824573 scopus 로고    scopus 로고
    • B-cell depletion with rituximab-A targeted therapy for Graves' disease and autoimmune thyroiditis
    • H.C. Hasselbalch B-cell depletion with rituximab-A targeted therapy for Graves' disease and autoimmune thyroiditis Immunol. Lett. 88 1 2003 85 86
    • (2003) Immunol. Lett. , vol.88 , Issue.1 , pp. 85-86
    • Hasselbalch, H.C.1
  • 96
    • 1842474927 scopus 로고    scopus 로고
    • Rituximab for primary chronic cold agglutinin disease: A prospective study of 37 courses of therapy in 27 patients
    • S. Berentsen Rituximab for primary chronic cold agglutinin disease: a prospective study of 37 courses of therapy in 27 patients Blood 103 8 2004 2925 2928
    • (2004) Blood , vol.103 , Issue.8 , pp. 2925-2928
    • Berentsen, S.1
  • 97
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
    • J.A. Gross TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease Nature 404 6781 2000 995 999
    • (2000) Nature , vol.404 , Issue.6781 , pp. 995-999
    • Gross, J.A.1
  • 98
    • 8444223507 scopus 로고    scopus 로고
    • Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus
    • J.H. Anolik Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus Arthritis Rheum. 50 11 2004 3580 3590
    • (2004) Arthritis Rheum. , vol.50 , Issue.11 , pp. 3580-3590
    • Anolik, J.H.1
  • 99
    • 0034669990 scopus 로고    scopus 로고
    • Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus
    • M. Odendahl Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus J. Immunol. 165 10 2000 5970 5979
    • (2000) J. Immunol. , vol.165 , Issue.10 , pp. 5970-5979
    • Odendahl, M.1
  • 100
    • 0033932756 scopus 로고    scopus 로고
    • CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus
    • M. Mihara CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus J. Clin. Invest. 106 1 2000 91 101
    • (2000) J. Clin. Invest. , vol.106 , Issue.1 , pp. 91-101
    • Mihara, M.1
  • 101
    • 0037868032 scopus 로고    scopus 로고
    • Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition
    • L. Schiffer Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition J. Immunol. 171 1 2003 489 497
    • (2003) J. Immunol. , vol.171 , Issue.1 , pp. 489-497
    • Schiffer, L.1


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