Treatment of refractory chronic GVHD with rituximab: A GITMO study

Bone Marrow Transplantation

Volumn 40, Issue 3, 2007, Pages 273-277

  Zaja, F ^a   Bacigalupo, A ^b   Patriarca, F ^a   Stanzani, M ^c   Van Lint, M T ^b   Fili C ^a   Scime R ^d   Milone, G ^e   Falda, M ^f   Vener, C ^g   Laszlo, D ^h   Alessandrino, P E ⁱ   Narni, F ^j   Sica, S ^k   Olivieri, A ^l   Sperotto, A ^a   Bosi, A ^m   Bonifazi, F ^c   Fanin, R ^a  

^a Azienda Ospedaliera Universitaria   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Ist Ematologia Oncol Medica L A   (Italy)

^d Divisione di Ematologia   (Italy)

^e Ospedale Ferrarotto   (Italy)

^f MAGGIORE HOSPITAL   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

^h EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

ⁱ FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^j UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^k CATHOLIC UNIVERSITY   (Italy)

^l Ospedale Regionale Torrette   (Italy)

^m Divisione di Ematologia   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; METHOXSALEN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RITUXIMAB; STEROID; TACROLIMUS;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTHROPATHY; ARTICLE; CANCER RELAPSE; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFICACY; DRUG RESPONSE; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; ENTEROPATHY; EYE DISEASE; FEMALE; FOLLOW UP; GRAM NEGATIVE SEPSIS; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INFECTION; INJECTION SITE REACTION; KIDNEY FAILURE; LIVER DISEASE; LUNG DISEASE; MALE; MOUTH DISEASE; MYASTHENIA GRAVIS; MYELOABLATIVE CONDITIONING; NONMYELOABLATIVE CONDITIONING; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PNEUMONIA; PRIORITY JOURNAL; PURE RED CELL ANEMIA; PUVA; RETROSPECTIVE STUDY; SKIN DISEASE; STEM CELL TRANSPLANTATION; SUDDEN DEATH; SURVIVAL RATE; THROMBOCYTOPENIA; TREMOR; VAGINA DISEASE;

ADULT; ANTIBODIES, MONOCLONAL; CHRONIC DISEASE; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HUMANS; IMMUNOLOGIC FACTORS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; SURVIVAL RATE;

EID: 34547185482     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705725     Document Type: Article

References (20)

1. Lee SJ, Vogelsang G, Gilman A, Weisdorf DJ, Pavletic S, Antin JH et al. A survey of diagnosis, management and grading of Chronic GVHD. Biol Blood Marrow Transplant 2002; 8: 32-39.
2. Goerner M, Gooley T, Flowers ME, Sullivan KM, Kiem HP, Sanders JE et al. Storb R. Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic aplastic or refractory anemias. Biol Blood Marrow Transplant 2002; 8: 47-56.
3. Koc S, Leisenring W, Flowers ME, Anasetti C, Deeg HJ, Nash RA et al. Therapy for chronic graft-versus-host disease: A randomized trial comparing cyclosporine plus prednisone versus prednisone alone. Blood 2002; 100: 48-51.
4. Cutler C, Miklos D, Kim HT, Treister N, Woo SB, Bienfang D. Rituximab for steroid-refractory chronic graft-vs.-host disease. Blood 2006; 108: 756-762.
5. Zaja F, Vianelli N, Sperotto A, De Vita S, Iacona I, Zaccaria A et al. B-cell compartment as the selective target for the treatment of immune thrombocytopenias. Haematologica 2003; 88: 538-546.
6. Zecca M, Nobili B, Ramenghi U, Perrotta S, Amendola G, Rosito P et al. Rituximab for the treatment of refractory autoimmune hemolytic anemia in children. Blood 2003; 101: 3857-3861.
7. Edwards JC, Szczepanski L, Szechinski J, Filipowicz-Sosnowska A, Emery P, Close DR et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 2004; 350: 2572-2581.
8. Zaja F, De Vita S, Mazzaro C, Sacco S, Damiani D, De Marchi D et al. Efficacy and safety of rituximab in type II mixed cryoglobulinemia. Blood 2003; 101: 3827-3834.
9. Anolik JH, Barnard J, Cappione A, Pugh-Bernard AE, Felgar RE, Looney RJ et al. Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis Rheum 2004; 50: 3580-3590.
10. Fakhouri F, Vernant JP, Veyradier A, Wolf M, Kaplanski G, Binaut R et al. Efficiency of curative and prophylactic treatment with rituximab in ADAMTS13-deficient thrombotic thrombocytopenic purpura: A study of 11 cases. Blood 2005; 106: 1932-1937.
11. Lee SJ, Vogelsang G, Flowers ME. Chronic graft-versus-host disease. Biol Blood Marrow Transplant 2003; 9: 215-233.
12. Zaja F, Russo D, Fuga G, Perella G, Baccarani M. Rituximab for myasthenia gravis developing after bone marrow transplant. Neurology 2000; 55: 1062-1063.
13. Abrahamsen IW, Somme S, Heldal D, Egeland T, Kvale D, Tjonnfjord GE. Immune reconstitution after allogeneic stem cell transplantation: The impact of stem cell source and graft-versus-host disease. Haematologica 2005; 90: 86-93.
14. Patriarca F, Skert C, Sperotto A, Zaja F, Falleti E, Mestroni R et al. The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-versus-host disease and immune recovery. Exp Hematol, 2006; 34: 389-396.
15. Ratanatharathorn V, Ayash L, Reynolds C, Silver S, Reddy P, Becker M et al. Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody. Biol Blood Marrow Transplant 2003; 9: 505-511.
16. Canninga-van Dijk MR, van der Straaten HM, Fijnheer R, Sanders CJ, van den Tweel JG, Verdonck LF. Anti-CD20 monoclonal antibody treatment in 6 patients with therapy-refractory chronic graft-versus-host disease. Blood 2004; 15: 2603-2606.
17. Okamoto M, Okano A, Akamatsu S, Ashihara E, Inaba T, Takenaka H et al. Rituximab is effective for steroid-refractory sclerodermatous chronic graft-versus-host disease. Leukemia 2006; 20: 172-173.
18. Sato S, Fujimoto M, Hasegawa M, Takehara K. Altered blood B lymphocyte homeostasis in systemic sclerosis. Expanded naive B cells and diminished but activated memory B cells. Arthritis Rheum 2004; 50: 1918-1927.
19. Famularo G, Giacomelli R, Alesse E, Cifone MG, Morrone S, Boirivant M et al. Polyclonal B lymphocyte activation in progressive systemic sclerosis. J Clin Lab Immunol 1989; 29: 59-63.
20. Hasegawa M, Hamaguchi Y, Yanaba K, Bouaziz JD, Uchida J, Fujimoto M et al. B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. Am J Pathol 2006; 169: 954-966.