메뉴 건너뛰기




Volumn 204, Issue , 2005, Pages 43-54

The role of BAFF in immune function and implications for autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR INHIBITOR; B CELL ACTIVATING FACTOR RECEPTOR; B CELL MATURATION ANTIGEN; BELIMUMAB; CELL SURFACE PROTEIN; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; FC RECEPTOR; LIGAND; MONOCLONAL ANTIBODY; PROTEIN INHIBITOR; RITUXIMAB; TRANSMEMBRANE ACTIVATOR AND CALCIUM MODULATOR AND CYCLOPHILIN LIGAND INTERACTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 16244423682     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2005.00219.x     Document Type: Review
Times cited : (120)

References (80)
  • 2
    • 0038651237 scopus 로고    scopus 로고
    • Improvement in Sjogren's syndrome following therapy with rituximab for marginal zone lymphoma
    • Somer BG, Tsai DE, Downs L, Weinstein B, Schuster SJ. Improvement in Sjogren's syndrome following therapy with rituximab for marginal zone lymphoma. Arthritis Rheum 2003;49:394-398.
    • (2003) Arthritis Rheum , vol.49 , pp. 394-398
    • Somer, B.G.1    Tsai, D.E.2    Downs, L.3    Weinstein, B.4    Schuster, S.J.5
  • 3
    • 0037318014 scopus 로고    scopus 로고
    • BAFF: B cell survival factor and emerging therapeutic target for autoimmune disorders
    • Kalled SL, Ambrose C, Hsu YM, BAFF: B cell survival factor and emerging therapeutic target for autoimmune disorders. Expert Opin Ther Targets 2003;7:115-123.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 115-123
    • Kalled, S.L.1    Ambrose, C.2    Hsu, Y.M.3
  • 5
    • 85060839632 scopus 로고    scopus 로고
    • The biochemistry and biology of BAFF, APRIL and their receptors
    • in press
    • Kalled SL, Ambrose C, Hsu YM. The biochemistry and biology of BAFF, APRIL and their receptors. Curr Dir Autoimmun (in press).
    • Curr Dir Autoimmun
    • Kalled, S.L.1    Ambrose, C.2    Hsu, Y.M.3
  • 6
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells
    • Nardelli B, et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 2000;97:198-204.
    • (2000) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1
  • 7
    • 0037415599 scopus 로고    scopus 로고
    • G-CSF-stimulated neutrophils are a prominent source of functional BLyS
    • Scapini P, et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med 2003;197:297-302.
    • (2003) J Exp Med , vol.197 , pp. 297-302
    • Scapini, P.1
  • 8
    • 1542269691 scopus 로고    scopus 로고
    • BAFF production by antigen-presenting cells provides T cell co-stimulation
    • Huard B, et al. BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol 2004;16:467-475.
    • (2004) Int Immunol , vol.16 , pp. 467-475
    • Huard, B.1
  • 9
    • 12144286821 scopus 로고    scopus 로고
    • BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex
    • Hase H, et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood 2004;103:2257-2265.
    • (2004) Blood , vol.103 , pp. 2257-2265
    • Hase, H.1
  • 10
    • 0141672920 scopus 로고    scopus 로고
    • Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells
    • Gorelik L, Gilbride K, Dobles M, Kalled SL, Zandman D, Scott ML. Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells. J Exp Med 2003;198:937-945.
    • (2003) J Exp Med , vol.198 , pp. 937-945
    • Gorelik, L.1    Gilbride, K.2    Dobles, M.3    Kalled, S.L.4    Zandman, D.5    Scott, M.L.6
  • 11
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • Thompson JS, et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 2001;293:2108-2111.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1
  • 12
    • 3142671331 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    • Ng LG, et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004;173:807-817.
    • (2004) J Immunol , vol.173 , pp. 807-817
    • Ng, L.G.1
  • 13
    • 9144244817 scopus 로고    scopus 로고
    • Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function
    • Gorelik L, et al. Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function. J Immunol 2004;172:762-766.
    • (2004) J Immunol , vol.172 , pp. 762-766
    • Gorelik, L.1
  • 14
    • 0037097665 scopus 로고    scopus 로고
    • Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
    • Hsu BL, Harless SM, Lindsley RC, Hilbert DM, Cancro MP. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol 2002;168:5993-5996.
    • (2002) J Immunol , vol.168 , pp. 5993-5996
    • Hsu, B.L.1    Harless, S.M.2    Lindsley, R.C.3    Hilbert, D.M.4    Cancro, M.P.5
  • 15
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • Schiemann B, et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 2001;293:2111-2114.
    • (2001) Science , vol.293 , pp. 2111-2114
    • Schiemann, B.1
  • 16
    • 17944375043 scopus 로고    scopus 로고
    • TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: Impaired B cell maturation in mice lacking BLyS
    • Gross JA, et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS. Immunity 2001;15:289-302.
    • (2001) Immunity , vol.15 , pp. 289-302
    • Gross, J.A.1
  • 17
    • 4043146475 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
    • Shulga-Morskaya S, et al. B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol 2004;173:2331-2341.
    • (2004) J Immunol , vol.173 , pp. 2331-2341
    • Shulga-Morskaya, S.1
  • 18
    • 0029039606 scopus 로고
    • BCMAp: An integral membrane protein in the Golgi apparatus of human mature B lymphocytes
    • Gras MP, et al. BCMAp: an integral membrane protein in the Golgi apparatus of human mature B lymphocytes. Int Immunol 1995;7:1093-1106.
    • (1995) Int Immunol , vol.7 , pp. 1093-1106
    • Gras, M.P.1
  • 19
    • 85047690330 scopus 로고    scopus 로고
    • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
    • Avery DT, et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 2003;112:286-297.
    • (2003) J Clin Invest , vol.112 , pp. 286-297
    • Avery, D.T.1
  • 20
    • 0942298590 scopus 로고    scopus 로고
    • Expression of BCMA, TACI, and BAFF-R in multiple myeloma: A mechanism for growth and survival
    • Novak AJ, et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 2004;103:689-694.
    • (2004) Blood , vol.103 , pp. 689-694
    • Novak, A.J.1
  • 21
    • 0039792391 scopus 로고    scopus 로고
    • NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
    • von Bulow GU, Bram RJ. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. Science 1997;278:138-141.
    • (1997) Science , vol.278 , pp. 138-141
    • Von Bulow, G.U.1    Bram, R.J.2
  • 22
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral response by TACI
    • von Bulow GU, van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI. Immunity 2001;14:573-582.
    • (2001) Immunity , vol.14 , pp. 573-582
    • Von Bulow, G.U.1    Van Deursen, J.M.2    Bram, R.J.3
  • 23
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • Yan M, et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2001;2:638-643.
    • (2001) Nat Immunol , vol.2 , pp. 638-643
    • Yan, M.1
  • 24
    • 0037332043 scopus 로고    scopus 로고
    • Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
    • Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 2003;18:279-288.
    • (2003) Immunity , vol.18 , pp. 279-288
    • Seshasayee, D.1    Valdez, P.2    Yan, M.3    Dixit, V.M.4    Tumas, D.5    Grewal, I.S.6
  • 25
    • 0034729769 scopus 로고    scopus 로고
    • Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
    • Marsters SA, Yan M, Pitti RM, Haas PE, Dixit VM, Ashkenazi A. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr Biol 2000;10:785-788.
    • (2000) Curr Biol , vol.10 , pp. 785-788
    • Marsters, S.A.1    Yan, M.2    Pitti, R.M.3    Haas, P.E.4    Dixit, V.M.5    Ashkenazi, A.6
  • 26
    • 0034634625 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
    • Wu Y, et al. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J Biol Chem 2000;275:35478-35485.
    • (2000) J Biol Chem , vol.275 , pp. 35478-35485
    • Wu, Y.1
  • 27
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
    • Yan M, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 2001;11:1547-1552.
    • (2001) Curr Biol , vol.11 , pp. 1547-1552
    • Yan, M.1
  • 28
    • 0037386743 scopus 로고    scopus 로고
    • Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis
    • Tan SM, et al. Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 2003;48:982-992.
    • (2003) Arthritis Rheum , vol.48 , pp. 982-992
    • Tan, S.M.1
  • 29
    • 0037108490 scopus 로고    scopus 로고
    • BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases
    • Roschke V, et al. BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol 2002;169:4314-4321.
    • (2002) J Immunol , vol.169 , pp. 4314-4321
    • Roschke, V.1
  • 30
    • 2942750585 scopus 로고    scopus 로고
    • Inverse association between circulating APRIL levels and serologic and clinical disease activities in patients with systemic lupus erythematosus
    • Stohl W, et al. Inverse association between circulating APRIL levels and serologic and clinical disease activities in patients with systemic lupus erythematosus. Ann Rheum Dis 2004;63:1096-1103.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1096-1103
    • Stohl, W.1
  • 31
    • 0036081039 scopus 로고    scopus 로고
    • APRIL modulates B and T cell immunity
    • Stein JV, et al. APRIL modulates B and T cell immunity. J Clin Invest 2002;109:1587-1598.
    • (2002) J Clin Invest , vol.109 , pp. 1587-1598
    • Stein, J.V.1
  • 32
    • 1642332951 scopus 로고    scopus 로고
    • Impaired IgA class switching in APRIL-deficient mice
    • Castigli E, et al. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci USA 2004;101:3903-3908.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3903-3908
    • Castigli, E.1
  • 33
    • 9144244788 scopus 로고    scopus 로고
    • APRIL-deficient mice have normal immune system development
    • Varfolomeev E, et al. APRIL-deficient mice have normal immune system development. Mol Cell Biol 2004;24:997-1006.
    • (2004) Mol Cell Biol , vol.24 , pp. 997-1006
    • Varfolomeev, E.1
  • 34
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
    • Schneider P, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999;189:1747-1756.
    • (1999) J Exp Med , vol.189 , pp. 1747-1756
    • Schneider, P.1
  • 35
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F, et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999;190:1697-1710.
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • Mackay, F.1
  • 36
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
    • Gross JA, et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 2000;404:995-999.
    • (2000) Nature , vol.404 , pp. 995-999
    • Gross, J.A.1
  • 37
    • 12944249540 scopus 로고    scopus 로고
    • Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
    • Khare SD, et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci USA 2000;97:3370-3375.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3370-3375
    • Khare, S.D.1
  • 38
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
    • Groom J, et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J Clin Invest 2002;109:59-68.
    • (2002) J Clin Invest , vol.109 , pp. 59-68
    • Groom, J.1
  • 39
    • 0142188050 scopus 로고    scopus 로고
    • Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice
    • Rahman ZS, Rao SP, Kalled SL, Mauser T. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med 2003;198:1157-1169
    • (2003) J Exp Med , vol.198 , pp. 1157-1169
    • Rahman, Z.S.1    Rao, S.P.2    Kalled, S.L.3    Mauser, T.4
  • 40
    • 0038446862 scopus 로고    scopus 로고
    • Cutting edge: Germinal centers formed in the absence of B cell-activating factor belonging to die TNF family exhibit impaired maturation and function
    • Vora KA, et al. Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to die TNF family exhibit impaired maturation and function. J Immunol 2003;171:547-551.
    • (2003) J Immunol , vol.171 , pp. 547-551
    • Vora, K.A.1
  • 41
    • 0034694088 scopus 로고    scopus 로고
    • BAFF mediates survival of peripheral immature B lymphocytes
    • Batten M, et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 2000;192:1453-1466.
    • (2000) J Exp Med , vol.192 , pp. 1453-1466
    • Batten, M.1
  • 42
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster JG, Hartley SB, Goodnow CC. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 1994;371:389-395.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 43
    • 0026533967 scopus 로고
    • Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice
    • Mason DY, Jones M, Goodnow CC. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. Int Immunol 1992;4:163-170.
    • (1992) Int Immunol , vol.4 , pp. 163-170
    • Mason, D.Y.1    Jones, M.2    Goodnow, C.C.3
  • 44
    • 0029550111 scopus 로고
    • Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
    • Cyster JG, Goodnow CC. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity 1995;3:691-701.
    • (1995) Immunity , vol.3 , pp. 691-701
    • Cyster, J.G.1    Goodnow, C.C.2
  • 45
    • 1842581849 scopus 로고    scopus 로고
    • Requirements for follicular exclusion and Bulletcompetitive elimination of autoantigen-binding B cells
    • Ekland EH, Forster R, Lipp M, Cyster JG. Requirements for follicular exclusion and Bulletcompetitive elimination of autoantigen-binding B cells. J Immunol 2004;172:4700-4708.
    • (2004) J Immunol , vol.172 , pp. 4700-4708
    • Ekland, E.H.1    Forster, R.2    Lipp, M.3    Cyster, J.G.4
  • 46
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
    • Lesley R, et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 2004;20:441-453.
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1
  • 47
    • 0141959215 scopus 로고    scopus 로고
    • Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
    • Enders A, Bouillet P, Puthalakath H, Xu Y, Tarlinton DM, Strasser A. Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. J Exp Med 2003;198:1119-1126.
    • (2003) J Exp Med , vol.198 , pp. 1119-1126
    • Enders, A.1    Bouillet, P.2    Puthalakath, H.3    Xu, Y.4    Tarlinton, D.M.5    Strasser, A.6
  • 48
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien M, et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 2004;20:785-798.
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1
  • 49
    • 0025255536 scopus 로고
    • The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1
    • Kurtz CB, O'Toole E, Christensen SM, Weis JH. The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1. J Immunol 1990;144:3581-3591.
    • (1990) J Immunol , vol.144 , pp. 3581-3591
    • Kurtz, C.B.1    O'Toole, E.2    Christensen, S.M.3    Weis, J.H.4
  • 50
    • 0025147480 scopus 로고
    • A molecular and immunochemical characterization of mouse CR2. Evidence for a single gene model of mouse complement receptors 1 and 2
    • Molina H, Kinoshita T, Inoue K, Carel JC, Holers VM. A molecular and immunochemical characterization of mouse CR2. Evidence for a single gene model of mouse complement receptors 1 and 2. J Immunol 1990;145:2974-2983.
    • (1990) J Immunol , vol.145 , pp. 2974-2983
    • Molina, H.1    Kinoshita, T.2    Inoue, K.3    Carel, J.C.4    Holers, V.M.5
  • 51
    • 2442670537 scopus 로고    scopus 로고
    • The complement system in B cell regulation
    • Carroll MC. The complement system in B cell regulation. Mol Immunol 2004;41:141-146.
    • (2004) Mol Immunol , vol.41 , pp. 141-146
    • Carroll, M.C.1
  • 52
    • 0141963793 scopus 로고    scopus 로고
    • Role of complement in the development of autoimmunity
    • Boackle SA, Holers VM. Role of complement in the development of autoimmunity. Curr Dir Autoimmun 2003;6:154-168.
    • (2003) Curr Dir Autoimmun , vol.6 , pp. 154-168
    • Boackle, S.A.1    Holers, V.M.2
  • 53
    • 0031202759 scopus 로고    scopus 로고
    • Mouse complement receptors type 1 (CR1; CD35) and type 2 (CR2; CD21): Expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice
    • Takahashi K, et al. Mouse complement receptors type 1 (CR1; CD35) and type 2 (CR2; CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice. J Immunol 1997;159:1557-1569.
    • (1997) J Immunol , vol.159 , pp. 1557-1569
    • Takahashi, K.1
  • 54
    • 0026587743 scopus 로고
    • CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
    • Carter RH, Fearon DT. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 1992;256:105-107.
    • (1992) Science , vol.256 , pp. 105-107
    • Carter, R.H.1    Fearon, D.T.2
  • 55
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow CC. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci USA 1996;93:2264-2271.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 56
    • 0029076561 scopus 로고
    • + T cells
    • + T cells. Nature 1995;376:181-184.
    • (1995) Nature , vol.376 , pp. 181-184
    • Rathmell, J.C.1
  • 57
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
    • Rathmell JC, Townsend SE, Xu JC, Flavell RA, Goodnow CC. Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 1996;87:319-329.
    • (1996) Cell , vol.87 , pp. 319-329
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.C.3    Flavell, R.A.4    Goodnow, C.C.5
  • 58
    • 0032562609 scopus 로고    scopus 로고
    • Dependence of germinal center B cells on expression of CD21/CD35 for survival
    • Fischer MB, et al. Dependence of germinal center B cells on expression of CD21/CD35 for survival. Science 1998;280:582-585.
    • (1998) Science , vol.280 , pp. 582-585
    • Fischer, M.B.1
  • 59
    • 0035652286 scopus 로고    scopus 로고
    • Cr2, a candidate gene in the murine Sle 1c lupus susceptibility locus, encodes a dysfunctional protein
    • Boackle SA, et al. Cr2, a candidate gene in the murine Sle 1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity 2001;15:775-785.
    • (2001) Immunity , vol.15 , pp. 775-785
    • Boackle, S.A.1
  • 60
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
    • Cheema GS, Roschke V, Hilbert DM, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 2001;44:1313-1319.
    • (2001) Arthritis Rheum , vol.44 , pp. 1313-1319
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3    Stohl, W.4
  • 61
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
    • Zhang J, et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001;166:6-10.
    • (2001) J Immunol , vol.166 , pp. 6-10
    • Zhang, J.1
  • 62
    • 10744224617 scopus 로고    scopus 로고
    • B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations
    • Stohl W, et al. B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum 2003;48:3475-3486.
    • (2003) Arthritis Rheum , vol.48 , pp. 3475-3486
    • Stohl, W.1
  • 63
    • 0037310430 scopus 로고    scopus 로고
    • The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome
    • Mariette X, et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome. Ann Rheum Dis 2003;62:168-171.
    • (2003) Ann Rheum Dis , vol.62 , pp. 168-171
    • Mariette, X.1
  • 64
    • 1842583827 scopus 로고    scopus 로고
    • Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
    • Lavie F, Miceli-Richard C, Quillard J, Roux S, Ledere P, Mariette X. Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. J Pathol 2004;202:496-502.
    • (2004) J Pathol , vol.202 , pp. 496-502
    • Lavie, F.1    Miceli-Richard, C.2    Quillard, J.3    Roux, S.4    Ledere, P.5    Mariette, X.6
  • 65
    • 0842269849 scopus 로고    scopus 로고
    • B-cell immunity in MS
    • Qin Y, Duquette P. B-cell immunity in MS. Int MS J 2003;10:110-120.
    • (2003) Int MS J , vol.10 , pp. 110-120
    • Qin, Y.1    Duquette, P.2
  • 66
    • 0032167731 scopus 로고    scopus 로고
    • Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis
    • Qin Y, Duquette P, Zhing Y, Talbot P, Poole R, Antel J. Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis. J Clin Invest 1998;102:1045-1050.
    • (1998) J Clin Invest , vol.102 , pp. 1045-1050
    • Qin, Y.1    Duquette, P.2    Zhing, Y.3    Talbot, P.4    Poole, R.5    Antel, J.6
  • 68
    • 0034163331 scopus 로고    scopus 로고
    • Accumulation of clonally related B lymphocytes in the cerebrospinal fluid of multiple sclerosis patients
    • Colombo M, et al. Accumulation of clonally related B lymphocytes in the cerebrospinal fluid of multiple sclerosis patients. J Immunol 2000;164:2782-2789.
    • (2000) J Immunol , vol.164 , pp. 2782-2789
    • Colombo, M.1
  • 69
    • 3042569128 scopus 로고    scopus 로고
    • Expression of B-cell-activating factor of the TNF family (BAFF) and its receptors in multiple sclerosis
    • Thangarajh M, Gomes A, Masterman T, Hillert J, Hjelmstrom P. Expression of B-cell-activating factor of the TNF family (BAFF) and its receptors in multiple sclerosis. J Neuroimmunol 2004;152:183-190.
    • (2004) J Neuroimmunol , vol.152 , pp. 183-190
    • Thangarajh, M.1    Gomes, A.2    Masterman, T.3    Hillert, J.4    Hjelmstrom, P.5
  • 70
    • 18644369740 scopus 로고    scopus 로고
    • BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2
    • Kayagaki N, et al. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 2002;17:515-524.
    • (2002) Immunity , vol.17 , pp. 515-524
    • Kayagaki, N.1
  • 71
    • 1242340285 scopus 로고    scopus 로고
    • Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis
    • Magliozzi R, Columba-Cabezas S, Serafini B, Aloisi F. Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. J Neuroimmunol 2004;148:11-23.
    • (2004) J Neuroimmunol , vol.148 , pp. 11-23
    • Magliozzi, R.1    Columba-Cabezas, S.2    Serafini, B.3    Aloisi, F.4
  • 72
    • 0035803468 scopus 로고    scopus 로고
    • Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
    • Schneider P, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med 2001;194:1691-1697.
    • (2001) J Exp Med , vol.194 , pp. 1691-1697
    • Schneider, P.1
  • 73
    • 0034918211 scopus 로고    scopus 로고
    • TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice
    • Wang H, et al. TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice. Nat Immunol 2001;2:632-637.
    • (2001) Nat Immunol , vol.2 , pp. 632-637
    • Wang, H.1
  • 74
    • 2442433618 scopus 로고    scopus 로고
    • Pathogenic roles of B cells in human autoimmunity: Insights from the clinic
    • Martin F, Chan AC. Pathogenic roles of B cells in human autoimmunity: insights from the clinic. Immunity 2004;20:517-527.
    • (2004) Immunity , vol.20 , pp. 517-527
    • Martin, F.1    Chan, A.C.2
  • 75
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells
    • O'Connor BP, et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 2004;199:91-98.
    • (2004) J Exp Med , vol.199 , pp. 91-98
    • O'Connor, B.P.1
  • 76
    • 0030140063 scopus 로고    scopus 로고
    • Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain
    • Morel L, Yu Y, Blenman KR, Caldwell RA, Wakeland EK. Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain. Mamm Genome 1996;7:335-339.
    • (1996) Mamm Genome , vol.7 , pp. 335-339
    • Morel, L.1    Yu, Y.2    Blenman, K.R.3    Caldwell, R.A.4    Wakeland, E.K.5
  • 77
    • 0034814052 scopus 로고    scopus 로고
    • Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus
    • Rozzo SJ, et al. Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity 2001;15:435-443.
    • (2001) Immunity , vol.15 , pp. 435-443
    • Rozzo, S.J.1
  • 78
    • 0036046296 scopus 로고    scopus 로고
    • + T cells: Lessons from HIV-infected patients
    • + T cells: lessons from HIV-infected patients. Clin Immunol 2002;104:115-122.
    • (2002) Clin Immunol , vol.104 , pp. 115-122
    • Stohl, W.1
  • 79
    • 0041326858 scopus 로고    scopus 로고
    • Plasma levels of B-lymphocyte stimulator increase with HIV disease progression
    • Rodriguez B, Valdez H, Freimuth W, Butler T, Asaad R, Lederman MM. Plasma levels of B-lymphocyte stimulator increase with HIV disease progression. Aids 2003;17:1983-1985.
    • (2003) Aids , vol.17 , pp. 1983-1985
    • Rodriguez, B.1    Valdez, H.2    Freimuth, W.3    Butler, T.4    Asaad, R.5    Lederman, M.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.