A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

EMBO Molecular Medicine

Volumn 2, Issue 2, 2010, Pages 51-62

  Rauschenberger, Katharina ^a   Schöler, Katja ^a,b   Sass, Jörn Oliver ^c   Sauer, Sven ^a   Djuric, Zdenka ^a   Rumig, Cordula ^d   Wolf, Nicole I ^a,e   Okun, Jürgen G ^a   Kölker, Stefan ^a   Schwarz, Heinz ^f   Fischer, Christine ^a   Grziwa, Beate ^a   Runz, Heiko ^a   Astrid, Nümann ^a   Shafqat, Naeem ^b   Kavanagh, Kathryn L ^b   Hämmering, Günter ^d   Wanders, Ronald J A ^g   Shield, Julian P H ^h   Wendel, Udo ⁱ   Stern, David ^j   Nawroth, Peter ^a   Hoffmann, Georg F ^a   Bartram, Claus R ^a   Arnold, Bernd ^d   Bierhaus, Angelika ^a   Oppermann, Udo ^b   Steinbeisser, Herbert ^a   Zschocke, Johannes ^a,k   more..

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF FREIBURG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^g UNIVERSITY OF AMSTERDAM   (Netherlands)

^h Royal Hospital for Children   (United Kingdom)

ⁱ UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^j UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^k INNSBRUCK MEDICAL UNIVERSITY   (Austria)

more..

Author keywords

Apoptosis; Erab; Hsd10; Neurodegeneration; Organic aciduria

Indexed keywords

2 METHYL 3 HYDROXYBUTYRYL COA DEHYDROGENASE; MUTANT PROTEIN; OXIDOREDUCTASE; TESTOSTERONE 17BETA DEHYDROGENASE; TESTOSTERONE 17BETA DEHYDROGENASE TYPE 10; UNCLASSIFIED DRUG;

2 METHYL 3 HYDROXYBUTYRYL COA DEHYDROGENASE DEFICIENCY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; FEMALE; HUMAN; HUMAN CELL; INFANT; LOSS OF FUNCTION MUTATION; MALE; MITOCHONDRION; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SCHOOL CHILD; XENOPUS;

3-HYDROXYACYL COA DEHYDROGENASES; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; FIBROBLASTS; GENE DELETION; GENETIC COMPLEMENTATION TEST; HUMANS; HYDROXYSTEROID DEHYDROGENASES; INFANT; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MODELS, MOLECULAR; NEURONS; PROTEIN STRUCTURE, TERTIARY; XENOPUS;

EID: 77953669220     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.200900055     Document Type: Article

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