Functional imaging of proteases: Recent advances in the design and application of substrate-based and activity-based probes

Current Opinion in Chemical Biology

Volumn 15, Issue 6, 2011, Pages 798-805

  Edgington, Laura E ^a   Verdoes, Martijn ^a   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CASPASE; CATHEPSIN; PROTEINASE; CYSTEINE PROTEINASE; FLUORESCENT DYE; HYDROLASE; PROTEIN; PROTEINASE INHIBITOR;

ENZYME ACTIVITY; HUMAN; MOLECULAR IMAGING; NONHUMAN; PROTEIN DEGRADATION; REVIEW; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; METABOLISM; METHODOLOGY; MOLECULAR LIBRARY; MOLECULAR PROBE; MOUSE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CYSTEINE PROTEASES; ENDOPEPTIDASES; FLUORESCENT DYES; HUMANS; HYDROLASES; MICE; MOLECULAR IMAGING; MOLECULAR PROBES; PROTEASE INHIBITORS; PROTEINS; PROTEOLYSIS; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 83055180536     PISSN: 13675931     EISSN: 18790402     Source Type: Journal    
DOI: 10.1016/j.cbpa.2011.10.012     Document Type: Review

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