Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 10, 2009, Pages 1444-1451

  Nahrendorf, Matthias ^a   Waterman, Peter ^a   Thurber, Greg ^a   Groves, Kevin ^b   Rajopadhye, Milind ^b   Panizzi, Peter ^a   Marinelli, Brett ^a   Aikawa, Elena ^a   Pittet, Mikael J ^a   Swirski, Filip K ^a   Weissleder, Ralph ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b VisEn Medical Inc   (United States)

Author keywords

Atherosclerosis; FMT CT; Inflammation; Molecular imaging; Protease activity

Indexed keywords

3 (2 ACETAMIDOETHYL)THIO 6 ETHYL 7 OXO 1 AZABICYCLO[3.2.0]HEPT 2 ENE 2 CARBOXYLIC ACID; ATORVASTATIN; CATHEPSIN B; FLUOROCHROME; NANOPARTICLE; PROTEINASE; PS 25; PS 40; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; DIAGNOSTIC AGENT; PEPTIDE HYDROLASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ATHEROSCLEROSIS; AORTA ROOT; ARTICLE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER MODEL; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MOLECULAR TOMOGRAPHY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MICROSCOPY; MOLECULAR IMAGING; MOUSE; NANOSENSOR; NONHUMAN; PLASMA HALF LIFE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOMOGRAPHY; ANIMAL; ATHEROSCLEROSIS; BIOLOGICAL MODEL; C57BL MOUSE; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETIC PROCEDURES; HALF LIFE TIME; METABOLISM; METHODOLOGY; PHYSIOLOGY;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BIOSENSING TECHNIQUES; FLOW CYTOMETRY; HALF-LIFE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NANOPARTICLES; PEPTIDE HYDROLASES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 70349565975     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.193086     Document Type: Article

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