Synthesis and histamine H 3 and H 4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376

Archiv der Pharmazie

Volumn 344, Issue 12, 2011, Pages 775-785

  Geyer, Roland ^a   Buschauer, Armin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Conformational restriction; Cyanoguanidines; H 4 receptor; Histamine; UR PI376

Indexed keywords

2 CYANO 1 [3 (1H IMIDAZOL 4 YL)BENZYL] 3 (3 PHENYLPROPYL)GUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)BENZYL] 3 [2 (PHENYLTHIO)ETHYL]GUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)BENZYL] 3 ISOBUTYLGUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)BENZYL] 3 METHYLGUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)PHENYL] 3 (3 PHENYLPROPYL)GUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)PHENYL] 3 [2 (PHENYLTHIO)ETHYL]GUANIDINE; 2 CYANO 1 [3 (1H IMIDAZOL 4 YL)PHENYL] 3 ISOBUTYLGUANIDINE; 2 CYANO 1 [4 (1H IMIDAZOL 4 YL)CYCLOHEXYL] 3 [2 (PHENYLTHIO)ETHYL]GUANIDINE; 2 CYANO 1 [4 (1H IMIDAZOL 4 YL)CYCLOHEXYL] 3 METHYLGUANIDINE; 2 CYANO 1 [4 (1H IMIDAZOL 4 YL)PHENYL] 3 METHYLGUANIDINE; 2 CYANO 3 CYCLOPROPYL 1 [3 (1H IMIDAZOL 4 YL)BENZYL]GUANIDINE; 2 CYANO 3 CYCLOPROPYL 1 [3 (1H IMIDAZOL 4 YL)PHENYL]GUANIDINE; 2 CYANO 3 CYCLOPROPYL 1 [4 (1H IMIDAZOL 4 YL)PHENYL]GUANIDINE; HISTAMINE AGONIST; UNCLASSIFIED DRUG; UR PI 376; VUF 5801; VUF 5803; VUF 5804;

ANIMAL CELL; ARTICLE; BINDING ASSAY; CELL MEMBRANE; CIS ISOMER; CONFORMATIONAL TRANSITION; DIASTEREOISOMER; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TRANS ISOMER;

ANIMALS; GUANIDINES; HISTAMINE AGONISTS; HUMANS; MOLECULAR CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 82955228124     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100144     Document Type: Article

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