Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 10, 2010, Pages 3173-3176

  Ghorai, Prasanta ^a   Kraus, Anja ^a   Birnkammer, Tobias ^a   Geyer, Roland ^a   Bernhardt, Günther ^a   Dove, Stefan ^a   Seifert, Roland ^b   Elz, Sigurd ^a   Buschauer, Armin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Acylguanidine; Chiral; Enantiomers; H2 receptor agonist; Histamine; Sf9 cells

Indexed keywords

2 AMINOTHIAZOLYLPROPYLGUANIDINE DERIVATIVE; 3 CYCLOHEXYLBUTANOIC ACID; 3 PHENYLBUTANOIC ACID; ARPROMIDINE; BENZENEBORONIC ACID; GUANOSINE TRIPHOSPHATASE; HISTAMINE H2 RECEPTOR AGONIST; IMIDAZOLYLPROPYLGUANIDINE DERIVATIVE; UNCLASSIFIED DRUG; GUANIDINE DERIVATIVE; HISTAMINE AGONIST; HISTAMINE H2 RECEPTOR; PROPYLGUANIDINE; RECOMBINANT PROTEIN;

ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ASSAY; GUINEA PIG; HEART RIGHT ATRIUM; STEREOCHEMISTRY; ANIMAL; CHEMISTRY; GENETICS; HUMAN; METABOLISM; STEREOISOMERISM; SYNTHESIS;

CAVIA;

ANIMALS; GUANIDINES; GUINEA PIGS; HISTAMINE AGONISTS; HUMANS; RECEPTORS, HISTAMINE H2; RECOMBINANT PROTEINS; STEREOISOMERISM;

EID: 77952100710     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.082     Document Type: Article

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