Protein deacetylation by sirtuins: Delineating a post-translational regulatory program responsive to nutrient and redox stressors

Cellular and Molecular Life Sciences

Volumn 67, Issue 18, 2010, Pages 3073-3087

  Bao, Jianjun ^a   Sack, Michael N ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Biological functions; Lysine acetylation deacetylation; NAD+; Post translational modifications; Sirtuins

Indexed keywords

RESVERATROL; SIRTUIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6; SIRTUIN 7; PROTEIN;

ALZHEIMER DISEASE; BIOLOGICAL ACTIVITY; CANCER THERAPY; CARCINOGENESIS; CELL FUNCTION; CIRCADIAN RHYTHM; DEACETYLATION; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; HEART FUNCTION; HUMAN; MOLECULAR PHYLOGENY; NONHUMAN; NUTRIENT CONCENTRATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REDOX STRESS; REVIEW; ACETYLATION; CLASSIFICATION; ENZYMOLOGY; METABOLISM; MITOCHONDRION; NEOPLASM; NERVE CELL; OXIDATION REDUCTION REACTION; PHYLOGENY;

ACETYLATION; HUMANS; MITOCHONDRIA; NEOPLASMS; NEURONS; OXIDATION-REDUCTION; PHYLOGENY; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SIRTUINS;

EID: 77956624414     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0402-y     Document Type: Review

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